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    Method and separating module for the separation of particles from a dispersion, in particular of blood corpuscles from blood
    8.
    发明授权
    Method and separating module for the separation of particles from a dispersion, in particular of blood corpuscles from blood 有权
    用于从分散体，特别是血液中分离颗粒的方法和分离模块

    公开(公告)号：US07527740B2

    公开(公告)日：2009-05-05

    申请号：US10492256

    申请日：2002-09-14

    申请人： Carlo Effenhauser ,  Gregor Ocvirk ,  Wolfgang Fiedler

    发明人： Carlo Effenhauser ,  Gregor Ocvirk ,  Wolfgang Fiedler

    IPC分类号： B01D37/00 ,  B01D11/00

    CPC分类号： G01N15/05 ,  A61M1/3693 ,  B01L3/502753 ,  B01L2200/0647 ,  B01L2300/0816 ,  G01N33/491 ,  G01N2015/055 ,  G01N2015/1486 ,  Y10T436/25 ,  Y10T436/25375

    摘要： A method for separating particles from a fluid dispersion, particularly for separating corpuscular components from biological samples, above all from blood. A separating module suitable for performing the method has a substrate with flow channels, comprising a feed channel for supplying the dispersion to a junction, a first drain channel for draining fluid having a reduced particle concentration away from the junction, and a second drain channel for draining fluid having an increased particle concentration away from the junction. The fluid flows so much faster in the second drain channel than in the first drain channel that due to the different flow speeds the dispersed particles preferentially flow at the junction further in the second drain channel.

    摘要翻译： 一种用于从流体分散体中分离颗粒的方法，特别是用于从生物样品中分离出红细胞成分，尤其是血液。 适于执行该方法的分离模块具有带有流动通道的基底，包括用于将分散体供应到结点的进料通道，用于排出离开结点的具有降低的粒子浓度的流体的第一排出通道和用于 具有离开结点的具有增加的颗粒浓度的排出流体。 在第二排水通道中流体流动比在第一排水通道中要快得多，由于不同的流速，分散的颗粒优先在第二排水通道中的结点处流动。

    Microfluidic element for analyzing a liquid sample
    10.
    发明授权
    Microfluidic element for analyzing a liquid sample 有权
    用于分析液体样品的微流体元件

    公开(公告)号：US08911684B2

    公开(公告)日：2014-12-16

    申请号：US13487707

    申请日：2012-06-04

    申请人： Manfred Augstein ,  Christoph Boehm ,  Carlo Effenhauser ,  Rijk Edwin Oosterbroek ,  Susanne Wuerl

    发明人： Manfred Augstein ,  Christoph Boehm ,  Carlo Effenhauser ,  Rijk Edwin Oosterbroek ,  Susanne Wuerl

    IPC分类号： B01L99/00 ,  B01F11/00 ,  B01F1/00 ,  B01F13/00 ,  B01L3/00 ,  B01F15/02 ,  B01F9/00

    CPC分类号： B01F1/0027 ,  B01F9/0014 ,  B01F11/0002 ,  B01F13/0059 ,  B01F15/0203 ,  B01F15/0233 ,  B01L3/502746 ,  B01L2200/16 ,  B01L2400/0409 ,  B01L2400/086

    摘要： A microfluidic element for analyzing a bodily fluid sample for an analyte contained therein is provided, the element having a substrate, a channel structure that is enclosed by the substrate, and a cover layer, and is rotatable around a rotational axis. The channel structure of the microfluidic element includes a feed channel having a feed opening, a ventilation channel having a ventilation opening, and at least two reagent chambers. The reagent chambers are connected to one another via two connection channels in such a manner that a fluid exchange is possible between the reagent chambers, one of the reagent chambers having an inlet opening, which has a fluid connection to the feed channel, so that a liquid sample can flow into the rotational-axis-distal reagent chamber. At least one of the reagent chambers contains a reagent, which reacts with the liquid sample.

    摘要翻译： 提供了用于分析其中​​包含的分析物的体液样品的微流体元件，所述元件具有衬底，由衬底包围的沟道结构和覆盖层，并且可围绕旋转轴线旋转。 微流体元件的通道结构包括具有进料口的进料通道，具有通风口的通风通道和至少两个试剂室。 试剂室通过两个连接通道彼此连接，使得可以在试剂室之间进行流体交换，其中一个试剂室具有与进料通道的流体连接的入口，从而使得 液体样品可以流入旋转轴远端试剂室。 至少一个试剂室含有与液体样品反应的试剂。