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公开(公告)号:US20130109080A1
公开(公告)日:2013-05-02
申请号:US13699763
申请日:2011-05-23
申请人: Joel R. Dufresne , David J. Franta , Theresa J. Gerten , Christopher R. Kokaisel , Kurt J. Halverson , William Bedingham , James E. Aysta , Barry W. Robole , Kenneth B. Wood
发明人: Joel R. Dufresne , David J. Franta , Theresa J. Gerten , Christopher R. Kokaisel , Kurt J. Halverson , William Bedingham , James E. Aysta , Barry W. Robole , Kenneth B. Wood
IPC分类号: B01L3/00
CPC分类号: B01L3/50273 , B01L3/5025 , B01L3/502707 , B01L3/502738 , B01L3/523 , B01L7/52 , B01L9/527 , B01L2200/0642 , B01L2200/0689 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887
摘要: Methods and devices for the thermal processing of samples are disclosed, including portable, integrated processing assemblies for occluding channels in a fluidic device.
摘要翻译: 公开了用于样品热处理的方法和装置,包括用于在流体装置中封闭通道的便携式集成处理组件。
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公开(公告)号:US20130122508A1
公开(公告)日:2013-05-16
申请号:US13699761
申请日:2011-05-23
申请人: William Bedingham , James E. Aysta , Barry W. Robole , Kenneth B. Wood , Theresa J. Gerten , Christopher R. Kokaisel , David J. Franta , Kurt J. Halverson , Joel R. Dufresne
发明人: William Bedingham , James E. Aysta , Barry W. Robole , Kenneth B. Wood , Theresa J. Gerten , Christopher R. Kokaisel , David J. Franta , Kurt J. Halverson , Joel R. Dufresne
CPC分类号: G01N1/28 , B01L3/5025 , B01L3/5027 , B01L3/502707 , B01L3/502738 , B01L3/523 , B01L7/52 , B01L9/527 , B01L2200/0642 , B01L2200/0689 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , G01N2035/00158 , Y10T436/25
摘要: Methods and devices for the thermal processing of samples are disclosed, including sample processing devices featuring an overflow region for retaining excess fluid, as well as portable sealing apparatuses for occluding channels in a sample processing device.
摘要翻译: 公开了用于样品的热处理的方法和装置,包括具有用于保留过量流体的溢流区域的样品处理装置,以及用于封闭样品处理装置中的通道的便携式密封装置。
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公开(公告)号:US20090162928A1
公开(公告)日:2009-06-25
申请号:US12396504
申请日:2009-03-03
IPC分类号: C12M1/00
CPC分类号: G01N21/0332 , B01L3/5025 , B01L3/502738 , B01L3/50851 , B01L7/52 , B01L2200/0642 , B01L2200/0689 , B01L2300/0829 , B01L2300/1805 , Y10T436/111666 , Y10T436/2575
摘要: Sample processing devices may include compression structures that provide for the transfer of force from a platen to a platform such as a thermal block on which the sample processing device is located during processing. The sample processing devices may include a fill reservoir structure with various features such as arcuate edges, radially aligned exit channels, support structures, and selectively variable heights with a corresponding variable volume distribution.
摘要翻译: 样品处理装置可以包括压缩结构,其提供将压力从压板传递到诸如加工过程中样品处理装置所处的热块的平台。 样品处理装置可以包括具有各种特征的填充储存器结构,例如弓形边缘,径向对准的出口通道,支撑结构以及具有相应的可变体积分布的选择性可变高度。
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公开(公告)号:US07507376B2
公开(公告)日:2009-03-24
申请号:US10325723
申请日:2002-12-19
IPC分类号: B01L3/00
CPC分类号: G01N21/0332 , B01L3/5025 , B01L3/502738 , B01L3/50851 , B01L7/52 , B01L2200/0642 , B01L2200/0689 , B01L2300/0829 , B01L2300/1805 , Y10T436/111666 , Y10T436/2575
摘要: Sample processing devices may include compression structures that provide for the transfer of force from a platen to a platform such as a thermal block on which the sample processing device is located during processing. The sample processing devices may include a fill reservoir structure with various features such as arcuate edges, radially aligned exit channels, support structures, and selectively variable heights with a corresponding variable volume distribution.
摘要翻译: 样品处理装置可以包括压缩结构,其提供将压力从压板传递到诸如加工过程中样品处理装置所处的热块的平台。 样品处理装置可以包括具有各种特征的填充储存器结构,例如弓形边缘,径向对准的出口通道,支撑结构以及具有相应的可变体积分布的选择性可变高度。
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公开(公告)号:USD463570S1
公开(公告)日:2002-09-24
申请号:US29144255
申请日:2001-06-28
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公开(公告)号:US06627159B1
公开(公告)日:2003-09-30
申请号:US09710184
申请日:2000-11-10
申请人: William Bedingham , Joel R. Dufresne , Michael R. Harms , Richard R. Matner , Diane North , Kenneth B. Wood
发明人: William Bedingham , Joel R. Dufresne , Michael R. Harms , Richard R. Matner , Diane North , Kenneth B. Wood
IPC分类号: B01L300
CPC分类号: G01N35/00069 , B01L3/5025 , B01L3/50255 , B01L3/502707 , B01L3/502738 , B01L7/52 , B01L7/525 , B01L9/527 , B01L2200/0642 , B01L2200/0689 , B01L2200/142 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2400/0406 , B01L2400/0409 , B01L2400/0481 , B01L2400/0655 , B01L2400/0661 , F27B9/16 , F27D5/00 , Y10T436/25 , Y10T436/2575
摘要: The present invention provides methods and devices for distributing sample material to a plurality of process chambers in a sample processing device by rotating the device about an axis of rotation. The process chambers are located along conduits extending from a loading chamber and, together, the loading chamber, conduits, and process chambers form process arrays that are aligned along a length of the sample processing devices. The process arrays are unvented, i.e., access to the interior volume of the process arrays is available only through the loading chamber. Also disclosed are methods of centrifugally loading sample material into the process chambers, as well as an assembly including a sample processing device and a carrier.
摘要翻译: 本发明提供了通过围绕旋转轴旋转设备来将样品材料分配到样品处理装置中的多个处理室的方法和装置。 处理室沿着从加载室延伸的管道定位,并且一起,装载室,导管和处理室形成沿着样品处理装置的长度对准的工艺阵列。 过程阵列是不受影响的,即,只能通过装载室访问过程阵列的内部空间。 还公开了将样品材料离心加载到处理室中的方法,以及包括样品处理装置和载体的组件。
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公开(公告)号:US08865091B2
公开(公告)日:2014-10-21
申请号:US12749763
申请日:2010-03-30
CPC分类号: B01L3/502715 , B01L3/502707 , B01L2200/12 , B01L2300/0812 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2300/168 , G01N21/0303 , Y10S436/809 , Y10T156/1002 , Y10T156/1052 , Y10T156/1082
摘要: Sample processing devices that include transmissive layers and control layers to reduce or eliminate cross-talk between process chambers in the processing device are disclosed. The transmissive layers may transmit significant portions of signal light and/or interrogation light while the control layers block significant portions of signal light and/or interrogation light. Methods of manufacturing processing devices that include transmissive layers and control layers are also disclosed. The methods may involve continuous forming processes including co-extrusion of materials to form the transmissive layer and control layer in a processing device, followed by formation of the process chambers in the control layer. Alternatively, the methods may involve extrusion of materials for the control layer, followed by formation of process chambers in the control layer.
摘要翻译: 公开了包括透射层和控制层以减少或消除处理装置中的处理室之间的串扰的样品处理装置。 透射层可以传输信号光和/或询问光的大部分,同时控制层阻挡信号光和/或询问光的重要部分。 还公开了制造包括透射层和控制层的处理装置的方法。 所述方法可以包括连续的成形方法,包括共挤出材料以在处理装置中形成透射层和控制层,随后在控制层中形成处理室。 或者,所述方法可以包括挤出用于对照层的材料,随后在对照层中形成处理室。
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公开(公告)号:US20100183479A1
公开(公告)日:2010-07-22
申请号:US12749763
申请日:2010-03-30
CPC分类号: B01L3/502715 , B01L3/502707 , B01L2200/12 , B01L2300/0812 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2300/168 , G01N21/0303 , Y10S436/809 , Y10T156/1002 , Y10T156/1052 , Y10T156/1082
摘要: Sample processing devices that include transmissive layers and control layers to reduce or eliminate cross-talk between process chambers in the processing device are disclosed. The transmissive layers may transmit significant portions of signal light and/or interrogation light while the control layers block significant portions of signal light and/or interrogation light. Methods of manufacturing processing devices that include transmissive layers and control layers are also disclosed. The methods may involve continuous forming processes including co-extrusion of materials to form the transmissive layer and control layer in a processing device, followed by formation of the process chambers in the control layer. Alternatively, the methods may involve extrusion of materials for the control layer, followed by formation of process chambers in the control layer.
摘要翻译: 公开了包括透射层和控制层以减少或消除处理装置中的处理室之间的串扰的样品处理装置。 透射层可以传输信号光和/或询问光的大部分,同时控制层阻挡信号光和/或询问光的重要部分。 还公开了制造包括透射层和控制层的处理装置的方法。 所述方法可以包括连续的成形方法,包括共挤出材料以在处理装置中形成透射层和控制层,随后在控制层中形成处理室。 或者,所述方法可以包括挤出用于对照层的材料,随后在对照层中形成处理室。
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公开(公告)号:US07718133B2
公开(公告)日:2010-05-18
申请号:US10682597
申请日:2003-10-09
IPC分类号: B01L3/00
CPC分类号: B01L3/502715 , B01L3/502707 , B01L2200/12 , B01L2300/0812 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2300/168 , G01N21/0303 , Y10S436/809 , Y10T156/1002 , Y10T156/1052 , Y10T156/1082
摘要: Sample processing devices that include transmissive layers and control layers to reduce or eliminate cross-talk between process chambers in the processing device are disclosed. The transmissive layers may transmit significant portions of signal light and/or interrogation light while the control layers block significant portions of signal light and/or interrogation light. Methods of manufacturing processing devices that include transmissive layers and control layers are also disclosed. The methods may involve continuous forming processes including co-extrusion of materials to form the transmissive layer and control layer in a processing device, followed by formation of the process chambers in the control layer. Alternatively, the methods may involve extrusion of materials for the control layer, followed by formation of process chambers in the control layer.
摘要翻译: 公开了包括透射层和控制层以减少或消除处理装置中的处理室之间的串扰的样品处理装置。 透射层可以传输信号光和/或询问光的大部分,同时控制层阻挡信号光和/或询问光的重要部分。 还公开了制造包括透射层和控制层的处理装置的方法。 所述方法可以包括连续的成形方法,包括共挤出材料以在处理装置中形成透射层和控制层,随后在控制层中形成处理室。 或者,所述方法可以包括挤出用于对照层的材料,随后在对照层中形成处理室。
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公开(公告)号:US5333609A
公开(公告)日:1994-08-02
申请号:US885713
申请日:1992-05-19
IPC分类号: A61B5/145 , A61B5/00 , A61B5/03 , A61B5/1459 , A61M25/00
CPC分类号: A61B5/1459 , A61B5/032
摘要: An assembly for insertion into the cardiovascular system of a patient comprising a catheter having first and second lumens and a distal port. The first lumen opens at the distal port. A probe is received in the second lumen. The probe includes a sensor responsive to a constituent of blood for providing a signal which is related to the constituent. The catheter has a window for allowing the constituent of blood to pass from outside the catheter to the sensor while substantially preventing other constituents of blood from passing from the outside of the catheter to the sensor.
摘要翻译: 一种用于插入患者的心血管系统的组件,包括具有第一和第二腔和远端口的导管。 第一个管腔在远端口开口。 在第二管腔中接收探针。 探针包括响应于血液成分的传感器,用于提供与成分相关的信号。 导管具有用于允许血液成分从导管外部传递到传感器的窗口,同时基本上防止血液的其它成分从导管的外部通过到传感器。
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