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公开(公告)号：US10087471B2
公开(公告)日：2018-10-02
申请号：US15092829
申请日：2016-04-07
Applicant: Korea Institute of Science and Technology
Inventor： Youngsoon Um , Yunje Kim , Kyung Min Lee , Han Min Woo , Gyeongtaek Gong , Ki Yeon Kim
Abstract: The present disclosure relates to a hydrolysate of a mixture of lignocellulosic biomass and seaweed biomass. By mixing seaweed biomass with lignocellulosic biomass and then preparing a hydrolysate, lignocellulosic biomass-derived acetic acid is consumed together with seaweed biomass-derived mannitol. As a result, high sugar productivity can be maintained while reducing fermentation inhibitors. Because the present disclosure can solve the problem of lignocellulosic biomass of decreased fermentation efficiency due to lignocellulose-derived fermentation inhibitors and the problem of seaweed biomass of very low productivity in spite of long fermentation time, the hydrolysate according to the present disclosure may be used to produce biofuels and biochemicals economically.
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公开(公告)号：US20200149071A1
公开(公告)日：2020-05-14
申请号：US16551335
申请日：2019-08-26
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Sun Mi Lee , Phuong Nguyen Hoang Tran , Youngsoon Um , Gyeongtaek Gong , Ja Kyong Ko , Yeonjung Lee
IPC: C12N15/90 , C12N9/92 , C12N9/12 , C12N9/10 , C12P7/06 , C12N15/81 , C12N1/16 , C12N15/11 , C12N9/22 , C12N9/04 , C12N9/02
Abstract: The present specification relates to a transformed yeast strain capable of simultaneously utilizing xylose and glucose as carbon sources, a preparation method thereof and a biofuel production method using the same. The transformed yeast strain transforms a wild-type yeast strain incapable of using xylose as a carbon source and simultaneously convert glucose and xylose, thereby enabling high yield production of a biofuel. The economics and sustainability of the biofuel and biomaterial production processes can be highly enhanced by providing a strain which can easily be converted to a strain capable of producing a biofuel/material in a high yield through an additional modification.
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公开(公告)号：US09719095B2
公开(公告)日：2017-08-01
申请号：US14950425
申请日：2015-11-24
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Han Min Woo , Eun Mi Kim , Youngsoon Um , Gyeongtaek Gong , Sun Mi Lee , Yunje Kim
IPC: C12N15/52 , C12N15/72 , C12N15/71 , C12N9/10 , C12N9/88 , C12N9/04 , C12N9/12 , C12N9/90 , C12N15/70
CPC classification number: C12N15/52 , C12N9/0006 , C12N9/1029 , C12N9/1085 , C12N9/1205 , C12N9/1229 , C12N9/88 , C12N9/90 , C12N15/70 , C12N15/71 , C12N15/72 , C12Y101/01034 , C12Y203/01026 , C12Y205/01 , C12Y207/01036 , C12Y207/04002 , C12Y401/01033 , C12Y401/03 , C12Y503/03002
Abstract: Disclosed herein are an expression vector capable of expressing myrcene, an Escherichia coli strain transformed with the vector and having improved capability of producing myrcene and a method for producing myrcene and a method for recycling glycerol using the same. In an aspect, the transformed Escherichia coli strain of the present disclosure can produce myrcene with high purity on a large scale using glycerol or glucose as a carbon source. Also, the Escherichia coli strain of the present disclosure is economical and environment-friendly because it can produce high value-added myrcene using waste glycerol as a carbon source. In addition, the strongly volatile myrcene can be produced and isolated at the same time.
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公开(公告)号：US11285492B2
公开(公告)日：2022-03-29
申请号：US16393967
申请日：2019-04-25
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Sun Mi Lee , Yong-Sang Ryu , Eui-Sang Yu , Jiwon Kim , Ja Kyong Ko , Gyeongtaek Gong , Chulki Kim , Jae Hun Kim
Abstract: Disclosed herein are a screening method of high-efficiency biofuel-producing strains by a dielectrophoretic method using vertical nano-gap electrodes and a producing method of biofuel from the screened strains.
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公开(公告)号：US10435426B2
公开(公告)日：2019-10-08
申请号：US16198017
申请日：2018-11-21
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Youngsoon Um , Kyung Min Lee , Sun-Mi Lee , Hong Gon Kim , Gyeongtaek Gong
Abstract: The present disclosure relates to a method for separating sugars and acids with reduced energy consumption, including a step of diffusively dialyzing a first acid hydrolysate obtained by saccharifying biomass with an acid solution, thereby preparing a second acid hydrolysate wherein the concentration of the acid solution contained in the acid hydrolysate is decreased; and a step of electrolyzing the second acid hydrolysate, thereby separating sugars from the acid solution, which is advantageous in that less energy is consumed, the separated acid solution can be recycled directly without further treatment due to high concentration and loss of sugars can be minimized.
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Patent Agency Ranking
公开(公告)号：US20240352401A1
公开(公告)日：2024-10-24
申请号：US18521797
申请日：2023-11-28
Applicant: Korea Institute of Science and Technology
Inventor： Sun Mi LEE , Jiwon Kim , Hyeoncheol Son , Ja Kyong Ko , Gyeongtaek Gong , Jung Ho Ahn , Youngsoon Um
CPC classification number: C12N1/165 , C12N9/0008 , C12N15/815 , C12R2001/645 , C12Y102/01003
Abstract: The present disclosure discloses a strain having resistance by neutralizing furfural, an inhibitor derived from lignocellulosic biomass, based on a technique using aldehyde dehydrogenase and a method of using the same. According to the present disclosure, furfural, an inhibitor derived from lignocellulosic biomass, is neutralized based on a technique using aldehyde dehydrogenase, so that a resistant strain overexpresses aldehyde dehydrogenase (EcAldH) in Yarrowia lipolytica, which has the ability to produce yeast oil, and has resistance to furfural, a biomass-derived inhibitor. Accordingly, even in the medium containing furfural, it can provide excellent strain growth and yeast oil production ability.
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公开(公告)号：US10975448B2
公开(公告)日：2021-04-13
申请号：US16253581
申请日：2019-01-22
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Youngsoon Um , Joongsuk Kim , Sun-Mi Lee , Gyeongtaek Gong
Abstract: The present disclosure relates to a Clostridium sp. JS66 strain producing metabolites having 4 to 6 carbon atoms in a high yield. The strain produces metabolites having 6 carbon atoms in a significantly high yield while reducing the production of acetic acid and ethanol as by-products.
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8.发明授权Paenibacillus sp. CAA11 capable of saccharification and fermentation of cellulose and transformed strain thereof 有权Paenibacillus sp。 能够糖化和发酵纤维素及其转化菌株的CAA11公开(公告)号：US09574214B2
公开(公告)日：2017-02-21
申请号：US15088935
申请日：2016-04-01
Applicant: Korea Institute Of Science And Technology
Inventor： Youngsoon Um , Han Min Woo , Gyeongtaek Gong , Eun Sook Kim , Sukhyeong Cho
IPC: C12P7/06 , C12N9/24 , C12P7/56 , C12R1/01 , C12N1/20 , C12N1/22 , C12P7/54 , C12P7/40 , C12P7/10 , C12N9/42
CPC classification number: C12P7/56 , C12N1/20 , C12N1/22 , C12N9/2437 , C12P7/065 , C12P7/10 , C12P7/40 , C12P7/54 , C12P19/02 , C12P19/12 , C12R1/01 , C12Y302/01004 , Y02E50/16 , Y02E50/17
Abstract: The present disclosure relates to a novel strain capable of saccharifying and fermenting biomass-derived cellulose and a recombinant strain thereof with improved biomass saccharification capability. The present disclosure also relates to a method for producing a material useful as a bioenergy source material such as ethanol, acetic acid, formic acid, etc. using the strain or the recombinant strain. The strain or the recombinant strain may be usefully used in bioenergy industry.
Abstract translation: 本公开涉及能够糖化和发酵生物质衍生的纤维素的新菌株及其具有改善的生物质糖化能力的重组菌株。 本公开还涉及使用该菌株或重组菌株生产可用作生物能源材料如乙醇，乙酸，甲酸等的材料的方法。 菌株或重组菌株可用于生物能源工业。
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公开(公告)号：US11932895B2
公开(公告)日：2024-03-19
申请号：US17849571
申请日：2022-06-24
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Hyun Ju Oh , Youngsoon Um , Sun Mi Lee , Gyeongtaek Gong , Ja Kyong Ko
CPC classification number: C12P7/06 , C12P7/16 , C12R2001/145
Abstract: The present disclosure relates to a composition for preparing hexanol or butanol and a method for preparing hexanol or butanol using ethanol and synthesis gas, wherein the composition according to an aspect of the present disclosure is a medium composition containing ethanol as an active ingredient, and by culturing a strain producing hexanol or butanol after inoculating with a medium containing the composition and supplying synthesis gas, hexanol or butanol can be prepared economically using inexpensive synthesis gas, and hexanol or butanol can be prepared with high efficiency by focusing the flow of a carbon source consumed in a fermentation process to the production of hexanol or butanol.
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公开(公告)号：US11319556B2
公开(公告)日：2022-05-03
申请号：US16551335
申请日：2019-08-26
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Sun Mi Lee , Phuong Nguyen Hoang Tran , Youngsoon Um , Gyeongtaek Gong , Ja Kyong Ko , Yeonjung Lee
IPC: C12N15/90 , C12N1/16 , C12N15/81 , C12P7/06 , C12P7/16 , C12N9/04 , C12N9/02 , C12N9/10 , C12N9/12 , C12N9/92 , C12N15/11 , C12N9/22
Abstract: The present specification relates to a transformed yeast strain capable of simultaneously utilizing xylose and glucose as carbon sources, a preparation method thereof and a biofuel production method using the same. The transformed yeast strain transforms a wild-type yeast strain incapable of using xylose as a carbon source and simultaneously convert glucose and xylose, thereby enabling high yield production of a biofuel. The economics and sustainability of the biofuel and biomaterial production processes can be highly enhanced by providing a strain which can easily be converted to a strain capable of producing a biofuel/material in a high yield through an additional modification.
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