摘要:
The present invention relates to the use of strains of Parapoxvirus ovis as immunotherapeutic agents for immunodeficiencies of an infectious or non-infectious nature, and to the use of strains of Parapoxvirus ovis for treating tumor diseases and viral infections, and diseases which accompany them, and the use of strains of Parapoxvirus ovis for producing medicaments for use in humans and animals.
摘要:
The present invention relates to the use, in humans, of inactivated parapoxviruses for the prophylaxis and treatment of diseases which are accompanied by an increased deposition of collagen, with it being possible for both internal organs, such as the liver, and the skin and its appended structures, to be affected. The invention relates, in particular, to liver fibrosis and/or liver cirrhosis consequent upon virus hepatitis, or to ethanol-induced liver diseases and to cystic fibrosis.
摘要:
The present invention relates to the preparation and use of organ-specific, tissue-specific and/or cell-specific recombinant parapoxvirus ovis as a pathogen-specific and organ-specific, targeted immunotherapeutic agent for chronic viral infections and inflammatory, degenerative and proliferative diseases, in particular of the liver, and cancer.
摘要:
The invention relates to polynucleotides coding for the PPVO viral genome, to fragments of the polynucleotides coding for the PPVO genome and to polynucleotides coding for individual open reading frames (ORFs) of the PPVO viral genome. The invention also relates to recombinant proteins expressed from the above mentioned polynucleotides and to fragments of said recombinant proteins, and to the use of said recombinant proteins or fragments for the preparation of pharmaceutical compositions.
摘要:
A method of diagnosing a cooling subsystem of an engine system in response a parameter extracted from dynamic hydraulic pressure sensed in the cooling subsystem, and products and systems using same.
摘要:
A method includes sensing pressure within an engine cylinder, and estimating at least one other engine system parameter based on the sensed pressure. Another method includes designing an engine system, which includes one or more engine cylinder pressure sensors and one or more other engine system sensors. According to this method, the engine system is operated, and engine cylinder pressure is sensed using the engine cylinder pressure sensors, which are in communication with an engine cylinder of an engine of the engine system. Also, other engine system parameters are sensed to obtain at least one other engine system parameter using the other engine system sensors. The engine cylinder pressure is correlated to the at least one other engine system parameter, and engine cylinder pressure is used to replace or augment the at least one other engine system parameter that correlates to the engine cylinder pressure.
摘要:
The present invention relates to substituted chromanol derivatives, to processes for their preparation, to their use on their own or in combination for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders.
摘要:
A method of diagnosing a cooling subsystem of an engine system in response a parameter extracted from dynamic hydraulic pressure sensed in the cooling subsystem, and products and systems using same.
摘要:
The invention relates to a method for the production of a pharmaceutical composition for treating cancer by combining Parapoxvirus ovis with at least one anticancer agent. The invention furthermore relates to a method for treating a patient afflicted with cancer comprising the administration of Parapoxvirus ovis in combination with at least one anticancer agent.
摘要:
Another embodiment of the invention includes a method of controlling a turbocharger to achieve at least one of: produce air in excess of that required to operate a combustion engine at a specific power demand; control the flow of gas through the turbine; or control the turbine speed independent of boost pressure required to avoid specific speeds.