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    Sample holder for use in infrared spectroscopy
    1.
    发明授权
    Sample holder for use in infrared spectroscopy 有权

    公开(公告)号：US11022548B2

    公开(公告)日：2021-06-01

    申请号：US16607877

    申请日：2018-04-30

    Applicant: Ping Lin

    Inventor： Ping Lin ,  Xiaojun Liu

    IPC: G01N21/35 ,  G01N21/3577 ,  G01N21/03 ,  G01N21/3563

    Abstract: A device for holding samples to be analyzed using the infrared transmission spectroscopy comprised of three or more infrared transparent windows that creates unparalleled gaps while maintaining a consistent path length, which eliminates interference fringes and ensures that quantitative analysis can be achieved. The present invention allows the use of high refractive index material, silicon, as window material. The device using silicon windows can serve both purposes of sample storage and infrared measuring cell. All-purpose disposable sample holders are now possible. In one embodiment, a pre-assembled sample holder is most suitable for loading and analyzing flowable liquid samples. In another embodiment, a sample holder can be easily assembled after high-viscosity fluids and deformable solid samples are loaded. In an alternative embodiment, the device comprised of two or more infrared transparent windows and a reflective mirror can be used for quantitative analysis using transflection infrared spectroscopy.

    Plastic grain cutting and transporting mechanism
    3.
    发明申请
    Plastic grain cutting and transporting mechanism 审中-公开
    塑料切粒输送机构

    公开(公告)号：US20070102550A1

    公开(公告)日：2007-05-10

    申请号：US11267910

    申请日：2005-11-07

    Applicant: Ping Lin

    Inventor： Ping Lin

    IPC: B02C18/18

    CPC classification number: B02C18/086 ,  B02C18/22 ,  B02C21/00 ,  B29B17/0412 ,  B29B2017/0476 ,  B29B2017/0484 ,  B29B2017/0488 ,  Y02W30/521 ,  Y02W30/625

    Abstract: This mechanism employs an inlet support, which is located at the front side of the plastic grain-collector. A second plastic grain-collector is installed on the right side of the plastic grain-collector and the second plastic grain-collector is also a circular-tank-shaped container. The rotary cutter-holding base is located at the bottom of the collector, and there are three cutters held onto the rotary cutter-holding base. Three cutters for pulverization installed on the top of the cutter-holding base pulverize the plastic grains for the first time; the plastic grains are pulverized for the second time in the main plastic grain-collector. The cutting mechanism pulverizes the plastic grains with the help of the anti-gliding cutters at the inner wall of the plastic grain-collector, and by which it increases the performance of the pulverization. At last, by pushing the force induced from the rotation of the cutter-holding base, the plastic grains will move smoothly into the inlet. The main feature is that the raw materials processed initially in the second plastic grain-collector are pulverized thoroughly in the main plastic grain-collector. Since the performance of pulverization is improved, the better quality of the end product can be obtained.

    Abstract translation: 该机构采用位于塑料收集器前侧的入口支撑件。 第二塑料颗粒收集器安装在塑料颗粒收集器的右侧，第二塑料颗粒收集器也是圆形罐形容器。 旋转刀具保持座位于收集器的底部，并且有三个刀具保持在旋转刀具保持座上。 安装在刀架顶部的三台粉碎机首次粉碎塑料颗粒; 塑料颗粒在主要的塑料收集器中第二次粉碎。 切割机构借助于防滑刀在塑料颗粒收集器的内壁处粉碎塑料颗粒，从而提高粉碎性能。 最后，通过推动由刀具保持座旋转引起的力，塑料颗粒将顺利地进入入口。 其主要特征是将最初在第二塑料收集器中加工的原料在主要的塑料收集器中彻底粉碎。 由于粉碎性能得到改善，所以可以获得最终产品的质量。

    Method and apparatus for providing an interface for a messaging mailbox
    7.
    发明授权
    Method and apparatus for providing an interface for a messaging mailbox 有权
    用于为消息邮箱提供接口的方法和装置

    公开(公告)号：US07711856B1

    公开(公告)日：2010-05-04

    申请号：US10955197

    申请日：2004-09-30

    Applicant: Lin Lin ,  Ping Lin

    Inventor： Lin Lin ,  Ping Lin

    IPC: G06F15/16 ,  G06F13/00

    CPC classification number: H04M3/533 ,  H04M7/006

    Abstract: A method and apparatus for accessing messages from a message server. Messages are stored on the message server in their current format without transcoding. When a client opens a session with the message server, a data transfer rate is determined for the client. In response to a message retrieve request, the bit rate of the message is compared to the data transfer rate, and if less than the data transfer rate, the message is downloaded to the user terminal without transcoding. If the bit rate is greater than the data transfer rate, then the message is transcoded to a lower bit rate according to a codec supported by the user. The codec may be selected from a set of codecs supported by the user terminal. The user is provided with the capability to override the system selected codec, for example, to pick a codec for secure encoding or encryption.

    Abstract translation: 一种用于从消息服务器访问消息的方法和装置。 消息以当前格式存储在消息服务器上，无需转码。 当客户端与消息服务器打开会话时，为客户端确定数据传输速率。 响应于消息检索请求，将消息的比特率与数据传输速率进行比较，如果小于数据传输速率，则将消息下载到用户终端而不进行转码。 如果比特率大于数据传输速率，则根据用户支持的编解码器将消息转码为较低的比特率。 可以从用户终端支持的一组编解码器中选择编解码器。 为用户提供覆盖系统选择的编解码器的能力，例如选择用于安全编码或加密的编解码器。

    Methods and systems for incorporating a third user into an instant message session
    8.
    发明授权
    Methods and systems for incorporating a third user into an instant message session 有权
    将第三用户并入即时消息会话的方法和系统

    公开(公告)号：US08909718B2

    公开(公告)日：2014-12-09

    申请号：US13172098

    申请日：2011-06-29

    Applicant: Lin Lin ,  Ping Lin

    Inventor： Lin Lin ,  Ping Lin

    IPC: G06F15/16 ,  H04L12/64

    CPC classification number: H04L12/6418

    Abstract: A method and apparatus for incorporating a third user into an instant message (IM) session. In one embodiment, an IM server receives a first IM from a first user directed toward a second user. The IM server makes a determination that the second user is not available to respond to the first IM. In response to the determination, the IM server identifies a third user to whom the first IM is to be forwarded, and automatically forwards the first IM to the third user. In another embodiment, the IM server receives a transfer request from the second user to transfer the IM session from the second user to the third user. The IM server automatically determines a subset portion of a plurality of IMs communicated between the first user and the second user, and provides the transfer request and the subset portion to the third user.

    Abstract translation: 一种用于将第三用户并入即时消息（IM）会话的方法和装置。 在一个实施例中，IM服务器从第一用户接收指向第二用户的第一IM。 IM服务器确定第二用户无法响应第一个IM。 响应于该确定，IM服务器识别要向其转发第一IM的第三用户，并自动将第一IM转发给第三用户。 在另一个实施例中，IM服务器从第二用户接收传送请求，以将IM会话从第二用户传送到第三用户。 IM服务器自动确定在第一用户和第二用户之间传送的多个IM的子集部分，并且向第三用户提供传送请求和子集部分。

    Method and file structures for managing data on a flash disk
    9.
    发明授权
    Method and file structures for managing data on a flash disk 有权
    用于管理闪存盘上数据的方法和文件结构

    公开(公告)号：US07363420B2

    公开(公告)日：2008-04-22

    申请号：US10734280

    申请日：2003-12-15

    Applicant: Lin Lin ,  Ping Lin

    Inventor： Lin Lin ,  Ping Lin

    IPC: G06F12/00

    CPC classification number: G06F3/064 ,  G06F3/0614 ,  G06F3/0679 ,  G06F12/0246

    Abstract: A method, apparatus and data structure for managing data in a memory device. The memory device is divided into two volumes. The first volume is intended for storing relatively static data, i.e. data which does not change or is not rewritten frequently. The second volume is intended for storing dynamic data, i.e. data which is changed or rewritten frequently. Each of the volumes is divided into a number of blocks, for example erase blocks, with each block being divided into sectors. In the dynamic volume, each of the erase blocks has one sector allocated for storing metadata, and the remaining sectors in the erase block are available for storing data, other than metadata. In the static volume, each of erase blocks can store more than one sector of metadata, in addition to data other than metadata. The metadata may be stored in consecutive sectors in the erase blocks. According to another aspect, the data structure is suitable for flash disk memory devices and flash disk memory devices used for multimedia applications.

    Abstract translation: 一种用于管理存储器件中的数据的方法，装置和数据结构。 存储器件分为两卷。 第一卷用于存储相对静态的数据，即不改变或不被重写的数据。 第二卷用于存储动态数据，即经常改变或重写的数据。 每个卷被分成多个块，例如擦除块，每个块被划分成扇区。 在动态卷中，每个擦除块具有分配用于存储元数据的一个扇区，并且擦除块中的其余扇区可用于存储除了元数据之外的数据。 在静态卷中，除了元数据之外的数据之外，每个擦除块可以存储多于一个元数据扇区。 元数据可以存储在擦除块中的连续扇区中。 根据另一方面，数据结构适用于用于多媒体应用的闪存盘设备和闪存盘存储设备。

    METHODS AND COMPOSITIONS FOR DETECTING RARE CELLS FROM A BIOLOGICAL SAMPLE
    10.
    发明申请
    METHODS AND COMPOSITIONS FOR DETECTING RARE CELLS FROM A BIOLOGICAL SAMPLE 审中-公开

    公开(公告)号：US20080057505A1

    公开(公告)日：2008-03-06

    申请号：US11777962

    申请日：2007-07-13

    Applicant: Ping Lin ,  Andrea Ghetti ,  Wenge Shi ,  Mengjia Tang ,  Gioulnar Harvie ,  Huimin Tao ,  Guoliang Tao ,  Lei Wu ,  David Cerny ,  Jia Xu

    Inventor： Ping Lin ,  Andrea Ghetti ,  Wenge Shi ,  Mengjia Tang ,  Gioulnar Harvie ,  Huimin Tao ,  Guoliang Tao ,  Lei Wu ,  David Cerny ,  Jia Xu

    IPC: G01N33/574 ,  C12Q1/02 ,  C12Q1/68 ,  G01N33/00

    CPC classification number: C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/16 ,  G01N33/54346 ,  G01N33/56966 ,  G01N33/574 ,  G01N2333/70525 ,  G01N2333/70589 ,  G01N2800/52

    Abstract: The present invention provides methods and compositions for isolating and detecting rare cells from a biological sample containing other types of cells. In particular, the present invention includes a debulking step that uses a microfabricated filters for filtering fluid samples and the enriched rare cells can be used in a downstream process such as identifies, characterizes or even grown in culture or used in other ways. The invention also include a method of determining the aggressiveness of the tumor or of the number or proportion of cancer cells in the enriched sample by detecting the presence or amount of telomerase activity or telomerase nucleic acid or telomerase expression after enrichment of rare cells. This invention further provides an efficient and rapid method to specifically remove red blood cells as well as white blood cells from a biological sample containing at least one of each of red blood cells and white blood cells, resulting in the enrichment of rare target cells including circulating tumor cells (CTC), stromal cells, mesenchymal cells, endothelial cells, fetal cells, stem cells, non-hematopoietic cells etc from a blood sample. The method is based upon combination of immuno-microparticles (antibody coated microparticles) and density-based separation. The final enriched target cells can be subjected to a variety of analysis and manipulations, such as flowcytometry, PCR, immunofluorescence, immunocytochemistry, image analysis, enzymatic assays, gene expression profiling analysis, efficacy tests of therapeutics, culturing of enriched rare cells, and therapeutic use of enriched rare cells. In addition, depleted plasma protein and white blood cells can be optionally recovered, and subjected to other analysis such as inflammation studies, gene expression profiling, etc.

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