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公开(公告)号：US20110117150A1
公开(公告)日：2011-05-19
申请号：US12590858
申请日：2009-11-13
申请人： Philip A. Eckhoff , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Dennis J. Rivet , Elizabeth A. Sweeney , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Philip A. Eckhoff , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Dennis J. Rivet , Elizabeth A. Sweeney , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61K31/192 , A61K9/00 , A61K31/195 , A61P29/00
CPC分类号： A61K31/192 , A61B5/1116 , A61B5/112 , A61B5/1126 , A61B5/4528 , A61K31/195 , A61M37/0015 , A61M2005/3022 , A61M2037/0007 , A61M2037/0023 , A61M2037/0061
摘要： A device, a system, or a method is described for treating a disease or condition of one or more joints of articulating bone in a mammalian subject. A device is described which includes one or more substrates configured to contact one or more body contours at one or more joints of articulating bone of a mammalian subject; and an applicator supported by the one or more substrates and configured to inject one or more medicaments to one or more joint tissues of the mammalian subject.
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2.发明申请公开(公告)号：US20110029038A1
公开(公告)日：2011-02-03
申请号：US12462123
申请日：2009-07-28
申请人： Roderick A. Hyde , Muriel Y. Ishikawa , Eric C. Leuthardt , Dennis J. Rivet , Elizabeth A. Sweeney , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Roderick A. Hyde , Muriel Y. Ishikawa , Eric C. Leuthardt , Dennis J. Rivet , Elizabeth A. Sweeney , Lowell L. Wood, JR. , Victoria Y.H. Wood
CPC分类号： A61B5/04001 , A61B5/4052 , A61B5/6846 , A61N1/3601 , A61N1/36014 , A61N1/36078 , A61N1/3611 , A61N1/36139 , A61N1/37211
摘要： Described embodiments include a system, an apparatus, and a method. A described system includes a sensor device configured to sense a property of a mammal without physically contacting the mammal. The system also includes a signal generator configured to generate a signal indicative of the sensed property of the mammal. The system further includes a treatment decision device configured to determine in response to the signal indicative of the sensed property of the mammal a neuromodulation treatment regimen for administration to a nervous system component of the mammal. The system also includes a computer-readable medium configured to maintain and to provide access to information corresponding to the determined neuromodulation treatment regimen.
摘要翻译： 所描述的实施例包括系统，装置和方法。 所描述的系统包括被配置为感测哺乳动物的性质而不与哺乳动物物理接触的传感器装置。 该系统还包括被配置为产生指示哺乳动物感测到的特性的信号的信号发生器。 该系统还包括治疗决定装置，其被配置为响应于指示哺乳动物感测到的属性的信号确定用于给予哺乳动物的神经系统组分的神经调节治疗方案。 该系统还包括计算机可读介质，其配置为维持并提供对与确定的神经调节治疗方案相对应的信息的访问。
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3.发明申请Systems, devices, and methods including infection-Fighting and monitoring shunts 失效系统，设备和方法，包括感染 - 战斗和监视分流公开(公告)号：US20100249692A1
公开(公告)日：2010-09-30
申请号：US12800791
申请日：2010-05-21
申请人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61M5/00
CPC分类号： A61N5/0601 , A61B5/0084 , A61B5/053 , A61B5/145 , A61B5/14503 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1459 , A61B5/1473 , A61B5/412 , A61B18/20 , A61L2/0011 , A61L2/08 , A61L2/14 , A61L2202/24 , A61M5/14276 , A61M27/006 , A61N1/205 , A61N1/37252 , A61N1/3785 , A61N1/3787 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/0624 , A61N5/10 , A61N7/00 , A61N2005/0651 , A61N2005/0652 , A61N2005/0661
摘要： Systems, devices, methods, and compositions are described for providing an actively controllable shunt configured to, for example, monitor, treat, or prevent an infection.
摘要翻译： 描述了用于提供被配置为例如监视，治疗或预防感染的主动控制分路的系统，装置，方法和组合物。
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公开(公告)号：US20100241054A1
公开(公告)日：2010-09-23
申请号：US12800792
申请日：2010-05-21
申请人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61M1/00
CPC分类号： A61N5/0601 , A61B5/0084 , A61B5/053 , A61B5/145 , A61B5/14503 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1459 , A61B5/1473 , A61B5/412 , A61B18/20 , A61L2/0011 , A61L2/08 , A61L2/14 , A61L2202/24 , A61M5/14276 , A61M27/006 , A61N1/205 , A61N1/37252 , A61N1/3785 , A61N1/3787 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/0624 , A61N5/10 , A61N7/00 , A61N2005/0651 , A61N2005/0652 , A61N2005/0661
摘要： Systems, devices, methods, and compositions are described for providing an actively controllable shunt configured to, for example, monitor, treat, or prevent an infection.
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5.发明申请Systems, devices and methods including infection-fighting and monitoring shunts 审中-公开系统，设备和方法，包括感染和监测分流公开(公告)号：US20100234793A1
公开(公告)日：2010-09-16
申请号：US12800780
申请日：2010-05-21
申请人： Ralph Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Lowell L. Wood, JR. , Victoria Y.H. Wood , Clarence T. Tegreene
发明人： Ralph Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Lowell L. Wood, JR. , Victoria Y.H. Wood , Clarence T. Tegreene
IPC分类号： A61M27/00
CPC分类号： A61N5/0601 , A61B5/0084 , A61B5/053 , A61B5/145 , A61B5/14503 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1459 , A61B5/1473 , A61B5/412 , A61B18/20 , A61L2/0011 , A61L2/08 , A61L2/14 , A61L2202/24 , A61M5/14276 , A61M27/006 , A61N1/205 , A61N1/37252 , A61N1/3785 , A61N1/3787 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/0624 , A61N5/10 , A61N7/00 , A61N2005/0651 , A61N2005/0652 , A61N2005/0661
摘要： Systems, devices, methods, and compositions are described for providing an actively controllable shunt configured to, for example, monitor, treat, or prevent an infection.
摘要翻译： 描述了用于提供被配置为例如监测，治疗或预防感染的主动控制分路的系统，装置，方法和组合物。
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6.发明申请System, devices, and methods including actively-controllable sterilizing excitation delivery implants 有权系统，装置和方法，包括主动控制的消毒激励输送植入物公开(公告)号：US20100174346A1
公开(公告)日：2010-07-08
申请号：US12592976
申请日：2009-12-03
申请人： Edward S. Boyden , Ralph G. Dacey, JR. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Edward S. Boyden , Ralph G. Dacey, JR. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61F7/00
CPC分类号： A61F2/02 , A61F2/30 , A61F2002/009 , A61F2002/30087 , A61F2002/3067 , A61F2002/30677 , A61F2002/3068 , A61F2002/3084 , A61F2002/30932 , A61F2002/481 , A61F2002/482 , A61F2250/0002 , A61F2250/0068 , A61F2310/00616 , A61L2/0011 , A61L2/0023 , A61L2/0029 , A61L2/0088 , A61L2/025 , A61L2/03 , A61N1/205 , A61N1/36 , A61N1/37252 , A61N1/3785 , A61N1/3787
摘要： Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
摘要翻译： 描述了用于提供主动控制的消毒可植入装置的系统，装置，方法和组合物，其被配置为例如治疗或预防生物学对象中的感染。
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公开(公告)号：US20100052898A1
公开(公告)日：2010-03-04
申请号：US12231061
申请日：2008-08-27
申请人： Paul G. Allen , Edward S. Boyden , Mahalaxmi Gita Bangera , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Eric C. Leuthardt , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Paul G. Allen , Edward S. Boyden , Mahalaxmi Gita Bangera , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Eric C. Leuthardt , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： G08B1/08
CPC分类号： A61B5/6833 , A61B5/01 , A61B5/02007 , A61B5/04 , A61B5/0816 , A61B5/1112 , A61B5/202 , A61B5/411 , A61B5/4875 , A61B5/6804 , A61B5/681 , A61B5/6831
摘要： Systems and methods are described for configuring and using displays, speakers, or other output devices positioned by an article of clothing or other such structure wearable by a healthcare recipient, for example, in a clinic or residential care facility.
摘要翻译： 描述了用于配置和使用由衣物制品定位的显示器，扬声器或其他输出设备的系统和方法，例如在诊所或安老院设置中，医疗保健接收者可佩戴其他此类结构。
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公开(公告)号：US20100035855A1
公开(公告)日：2010-02-11
申请号：US12584046
申请日：2009-08-28
申请人： Roderick A. Hyde , Muriel Y. Ishikawa , Eric C. Leuthardt , Dennis J. Rivet , Elizabeth A. Sweeney , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Roderick A. Hyde , Muriel Y. Ishikawa , Eric C. Leuthardt , Dennis J. Rivet , Elizabeth A. Sweeney , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61K31/56
CPC分类号： A61K31/00 , A61K31/415 , A61K31/423 , A61K45/06 , A61K2300/00
摘要： A method for treating cardiovascular disease in a mammalian subject includes providing to the subject at least one treatment regimen including at least one estrogen receptor modulator, wherein the at least one treatment regimen is determined based on the APOE allelic profile in the subject, and based on the steroid hormone levels prior to disease diagnosis and on current steroid hormone levels in the subject.
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9.发明申请Systems, devices, and methods including catheters having components that are actively controllable between two or more wettability states 有权系统，装置和方法，包括具有可在两个或多个润湿性状态之间主动控制的组分的导管公开(公告)号：US20110152789A1
公开(公告)日：2011-06-23
申请号：US12927284
申请日：2010-11-10
申请人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
CPC分类号： A61F2/30 , A61F2/32 , A61F2002/30031 , A61F2002/30087 , A61F2002/30668 , A61F2002/3067 , A61F2002/30677 , A61F2002/48 , A61F2002/481 , A61F2002/482 , A61F2250/0001 , A61F2250/0002 , A61F2250/0056 , A61F2310/0097 , A61L2/0011 , A61L2/08 , A61L2/14 , A61L2202/14 , A61L2202/24 , A61N1/205 , A61N1/37252 , A61N1/3785 , A61N1/3787
摘要： Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
摘要翻译： 描述了用于提供主动控制的消毒可植入装置的系统，装置，方法和组合物，其被配置为例如治疗或预防生物学对象中的感染。
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10.发明申请Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject 有权用于向哺乳动物受试者靶向递送抗炎药物的装置，系统和方法公开(公告)号：US20110118697A1
公开(公告)日：2011-05-19
申请号：US12660111
申请日：2010-02-19
申请人： Philip A. Eckhoff , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Dennis J. Rivet , Elizabeth A. Sweeney , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Philip A. Eckhoff , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Dennis J. Rivet , Elizabeth A. Sweeney , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61M31/00
CPC分类号： A61K31/192 , A61B5/1116 , A61B5/112 , A61B5/1126 , A61B5/4528 , A61K31/195 , A61M37/0015 , A61M2005/3022 , A61M2037/0007 , A61M2037/0023 , A61M2037/0061
摘要： A device, a system, or a method is described for treating a disease or a condition of one or more joints of articulating bone in a mammalian subject. The device provides one or more medicaments to one or more joints of the mammalian subject. A device is described that includes one or more substrates configured to contact one or more body contours in proximity to one or more joints of articulating bone of a mammalian subject; one or more sensors configured to detect one or more physiological conditions of the one or more joints; and one or more microjet applicators supported by the one or more substrates and configured to respond to the one or more sensors by injecting one or more medicaments to the one or more joint tissues of the mammalian subject.
摘要翻译： 描述了用于治疗哺乳动物受试者中关节骨的一个或多个关节的疾病或病症的装置，系统或方法。 该装置向哺乳动物受试者的一个或多个关节提供一种或多种药物。 描述了一种装置，其包括被配置为接触靠近哺乳动物受试者的关节骨的一个或多个关节的一个或多个身体轮廓的一个或多个基底; 一个或多个传感器被配置为检测所述一个或多个关节的一个或多个生理状况; 以及一个或多个由一个或多个基底支撑并且经配置以通过将一种或多种药物注射到哺乳动物受试者的一个或多个关节组织来响应于一个或多个传感器的微喷射施加器。
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