摘要:
Disclosed in one aspect is a method for performing a complete blood count (CBC) on a sample of whole blood by metering a predetermined amount of the whole blood and mixing it with a predetermined amount of diluent and stain and transferring a portion thereof to an imaging chamber of fixed dimensions and utilizing an automated microscope with digital camera and cell counting and recognition software to count every white blood cell and red blood corpuscle and platelet in the sample diluent/stain mixture to determine the number of red cells, white cells, and platelets per unit volume, and analyzing the white cells with cell recognition software to classify them.
摘要:
This disclosure describes single-use test cartridges, cell analyzer apparatus, and methods for automatically performing microscopic cell analysis tasks, such as counting blood cells in biological samples. A small unmeasured quantity of a biological sample such as whole blood is placed in the disposable test cartridge which is then inserted into the cell analyzer. The analyzer isolates a precise volume of the biological sample, mixes it with self-contained reagents and transfers the entire volume to an imaging chamber. The geometry of the imaging chamber is chosen to maintain the uniformity of the mixture, and to prevent cells from crowding or clumping, when it is transferred into the imaging chamber. Images of essentially all of the cellular components within the imaging chamber are analyzed to obtain counts per unit volume. The devices, apparatus and methods described may be used to analyze a small quantity of whole blood to obtain counts per unit volume of red blood cells, white blood cells, including sub-groups of white cells, platelets and measurements related to these bodies.
摘要:
A system and method for determining bone characteristic data is provided. The system combines a biochemical bone measuring unit with a densitometric bone measuring unit to determine the bone characteristic data. Once the bone characteristic data is ascertained, a determination of whether bone formation or bone resorption is occurring is made and future bone characteristics can be projected.
摘要:
The invention provides an improved rotating seal apparatus including a plurality of concentrically spaced annular rotating seals. The invention also provides a rotating seal apparatus including a pressurized annular chamber surrounding an annular rotating seal.
摘要:
A method and apparatus for selectively expressing one ore more selected fluid materials out of a fluid container, including a centrifuge rotor having a round centrifuge chamber of selected volume, a round expandable enclosure disposed within the centrifuge chamber having a rotation axis coincident with the central rotation axis and a flexible wall, a pump for controllably pumping a selected volume of expressor fluid into and out of the expandable enclosure wherein the fluid container is receivable within the centrifuge chamber, and a retaining mechanism for holding the fluid container within the centrifuge chamber in a coaxial position. The flexible wall of the fluid container is in contact with the flexible wall of the expandable enclosure.
摘要:
A device is provided for distributing a fluids from different sources to different destinations. The device receives fluids from a plurality of different sources and distributes the fluids out of a port to a destination. The device also receives fluid from the destination and transfers the fluid to another port out to another destination.
摘要:
A method of calibrating an ultrasound bone analysis apparatus having a pair of transducer assemblies. Each transducer assembly has a transducer and a coupling pad, and is movable relative to the other so that a face of each pad can be moved to a position in which they mutually contact and to a position where the faces contact body parts. The method according to the present application includes transmitting an ultrasound signal from one transducer and receiving a signal corresponding to the transmitted ultrasound signal through the other transducer when the transducer assemblies are in the first position and the second position. A time for the ultrasound signal to pass through the body part is determined, and a width of the body part based on positions of the transducers is determined. Then, using the time and width values a speed of sound of the ultrasound signal passing through the body part with squish compensation is calculated.
摘要:
A method of calibrating an ultrasound bone analysis apparatus having a pair of transducer assemblies. Each transducer assembly has a transducer and a coupling pad, and is movable relative to the other so that a face of each pad can be moved to a position in which they mutually contact and to a position where the faces contact body parts. The method according to the present application includes transmitting an ultrasound signal from one transducer and receiving a signal corresponding to the transmitted ultrasound signal through the other transducer when the transducer assemblies are in the first position and the second position. A time for the ultrasound signal to pass through the body part is determined, and a width of the body part based on positions of the transducers is determined. Then, using the time and width values a speed of sound of the ultrasound signal passing through the body part with squish compensation is calculated.
摘要:
An optical sensor is disclosed for use in an interactive cell processing system that includes a plurality of sensors arranged for monitoring and providing sensor data to a control module that directs processing of biological cells. The sensors including an optical sensor for characterizing a fluid transferred in a sterile manner during the processing. The optical sensor includes a light source, a light detector, a cuvette and a control circuit. The light source is connected to a control circuit and is constructed and arranged to emit light of at least one selected wavelength directed toward the fluid. The cuvette is constructed as a part of a fluid distribution manifold that includes several conduits for transferring the sterile fluid during the processing, wherein the cuvette is constructed and arranged to convey the fluid. The light detector is connected to the control circuit and is constructed and arranged to detect light that was emitted from the source and has interacted with the fluid flowing inside the cuvette. The control circuit is constructed and arranged to characterize the fluid in the cuvette based on the detected light.
摘要:
An ultrasonic bone testing apparatus has a foot well assembly and a shin guide assembly which are mechanically coupled to secure a foot and lower leg of patient. The shin guide assembly includes a molded form lined with contoured foam lining. An instep support guide having sliding blocks is mounted on the molded form. The sliding blocks attach the shin guide assembly to the foot well assembly. The apparatus further includes a transducer drive mechanism for positioning a pair of transducer assemblies. A controller automatically modifies the positioning of the transducer assemblies until ultrasonic coupling is achieved and a receiving transducer receives a signal of a predetermined quality. The distance between the transducers is continuously measured by a position encoder. The controller uses temperature readings from a temperature sensor to improve the accuracy of the position encoder measurements and correct for temperature dependent inaccuracy in the ultrasound measurement. A coupling pad and acoustical delay line of the transducer assembly provide a waveguide function to collimate an acoustical beam. The elastomer coupling pad has an angled surface which expels air bubbles from a contact area when pressure is applied to the pad.