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10 条记录 (耗时 0.026 秒)

    Conjugated biological molecules and their preparation
    1.
    发明授权
    Conjugated biological molecules and their preparation 有权
    共轭生物分子及其制备

    公开(公告)号：US07595292B2

    公开(公告)日：2009-09-29

    申请号：US10564340

    申请日：2004-07-12

    申请人： Stephen James Brocchini ,  Antony Robert Godwin ,  Elisa Pedone ,  Jin-Won Choi ,  Sunil Shaunak

    发明人： Stephen James Brocchini ,  Antony Robert Godwin ,  Elisa Pedone ,  Jin-Won Choi ,  Sunil Shaunak

    IPC分类号： A61K38/16 ,  A61K39/00

    CPC分类号： A61K47/48215 ,  A61K47/60

    摘要： Novel biologically active compounds of the general formula (I) in which one of X and X′ represents a polymer, and the other represents a hydrogen atom; each Q independently represents a linking group; W represents an electron-withdrawing moiety or a moiety preparable by reduction of an electron-withdrawing moiety; or, if X′ represents a polymer, X-Q-W- together may represent an electron withdrawing group; and in addition, if X represents a polymer, X′ and electron withdrawing group W together with the interjacent atoms may form a ring; each of Z1 and Z2 independently represents a group derived from a biological molecule, each of which is linked to A and B via a nucleophilic moiety; or Z1 and Z2 together represent a single group derived from a biological molecule which is linked to A and B via two nucleophilic moieties; A is a C1-5 alkylene or alkenylene chain; and B is a bond or a C1-4 alkylene or alkenylene chain; are formed by conjugating a suitable polymer to a suitable biologically active molecule via nucleophilic groups in said molecule, preferably via a disulphide bridge.

    摘要翻译： 通式（I）的新型生物活性化合物，其中X和X'之一表示聚合物，另一个表示氢原子; 每个Q独立地表示连接基团; W表示吸电子部分或可通过还原吸电子部分制备的部分; 或者如果X'代表聚合物，则X-Q-W一起可以代表吸电子基团; 此外，如果X表示聚合物，则X'和吸电子基团W与中间原子一起可以形成环; Z 1和Z 2各自独立地表示衍生自生物分子的基团，其各自经由亲核部分与A和B连接; 或Z 1和Z 2一起表示衍生自经由两个亲核部分与A和B连接的生物分子的单一基团; A是C 1-5亚烷基或亚烯基链; 和B是键或C 1-4亚烷基或亚烯基链; 通过将所述分子中的亲核基团，优选通过二硫桥将合适的聚合物与合适的生物活性分子缀合而形成。

    Conjugated biological molecules and their preparation
    2.
    发明申请
    Conjugated biological molecules and their preparation 有权
    共轭生物分子及其制备

    公开(公告)号：US20060210526A1

    公开(公告)日：2006-09-21

    申请号：US10564340

    申请日：2004-07-12

    申请人： Stephen Brocchini ,  Antony Godwin ,  Elisa Pedone ,  Jin-Won Choi ,  Sunil Shaunak

    发明人： Stephen Brocchini ,  Antony Godwin ,  Elisa Pedone ,  Jin-Won Choi ,  Sunil Shaunak

    IPC分类号： A61K38/16 ,  A61K31/785 ,  C08G63/91 ,  C08G63/48

    CPC分类号： A61K47/48215 ,  A61K47/60

    摘要： Novel biologically active compounds of the general formula (I) in which one of X and X′ represents a polymer, and the other represents a hydrogen atom; each Q independently represents a linking group; W represents an electron-withdrawing moiety or a moiety preparable by reduction of an electron-withdrawing moiety; or, if X′ represents a polymer, X-Q-W- together may represent an electron withdrawing group; and in addition, if X represents a polymer, X′ and electron withdrawing group W together with the interjacent atoms may form a ring; each of Z1 and Z2 independently represents a group derived from a biological molecule, each of which is linked to A and B via a nucleophilic moiety; or Z1 and Z2 together represent a single group derived from a biological molecule which is linked to A and B via two nucleophilic moieties; A is a C1-5 alkylene or alkenylene chain; and B is a bond or a C1-4 alkylene or alkenylene chain; are formed by conjugating a suitable polymer to a suitable biologically active molecule via nucleophilic groups in said molecule, preferably via a disulphide bridge.

    摘要翻译： 通式（I）的新型生物活性化合物，其中X和X'之一表示聚合物，另一个表示氢原子; 每个Q独立地表示连接基团; W表示吸电子部分或可通过还原吸电子部分制备的部分; 或者如果X'代表聚合物，则X-Q-W一起可以代表吸电子基团; 此外，如果X表示聚合物，则X'和吸电子基团W与中间原子一起可以形成环; Z 1和Z 2各自独立地表示衍生自生物分子的基团，其各自通过亲核部分连接到A和B; 或Z 1和Z 2一起代表衍生自经由两个亲核部分与A和B连接的生物分子的单一基团; A是C 1-5亚烷基或亚烯基链; 和B是键或C 1-4亚烷基或亚烯基链; 通过将所述分子中的亲核基团，优选通过二硫桥将合适的聚合物与合适的生物活性分子缀合而形成。

    Function execution method and apparatus thereof
    6.
    发明授权
    Function execution method and apparatus thereof 有权
    功能执行方法及其装置

    公开(公告)号：US09292199B2

    公开(公告)日：2016-03-22

    申请号：US12557322

    申请日：2009-09-10

    申请人： Jin-Won Choi

    发明人： Jin-Won Choi

    IPC分类号： G06F3/0488

    CPC分类号： G06F3/04886 ,  G06F3/0488 ,  G06F3/04883

    摘要： A function execution method and apparatus thereof for displaying one or more sub-functions included in a function selected by a first touch on a trace according to a second touch input based upon the first and the second touches inputted with a timing difference, and executing the relevant sub-function selected among the displayed one or more sub-functions. For this purpose, a function execution method according to the present invention is performed by comprising: detecting a first touch input touched on a display unit; detecting a drag created by a second touch inputted while maintaining the first touch; and displaying one or more sub-functions included in a function selected by the first touch along a trace of the detected drag on the display unit.

    摘要翻译： 一种功能执行方法及其装置，用于根据基于以定时差输入的第一触摸和第二触摸，根据第二触摸输入，在轨迹上由第一次触摸选择的功能中包含的一个或多个子功能，以及执行 在显示的一个或多个子功能中选择相关子功能。 为此，根据本发明的功能执行方法包括：检测在显示单元上触摸的第一触摸输入; 检测在保持第一次触摸的同时输入的第二触摸产生的拖动; 以及在所述显示单元上沿着所述检测到的拖动的迹线，显示包括在由所述第一触摸选择的功能中的一个或多个子功能。

    Printed circuit board for a package and manufacturing method thereof
    10.
    发明申请
    Printed circuit board for a package and manufacturing method thereof 审中-公开
    一种封装用印刷电路板及其制造方法

    公开(公告)号：US20090205854A1

    公开(公告)日：2009-08-20

    申请号：US12219140

    申请日：2008-07-16

    申请人： Dong-Gyu Lee ,  Jin-Won Choi ,  Ki-Young Yoo ,  Tae-Joon Chung

    发明人： Dong-Gyu Lee ,  Jin-Won Choi ,  Ki-Young Yoo ,  Tae-Joon Chung

    IPC分类号： H05K1/09 ,  H05K3/00

    CPC分类号： H05K3/243 ,  H01L2224/16 ,  H01L2924/01046 ,  H01L2924/01078 ,  H01L2924/01079 ,  H01L2924/01327 ,  H05K1/0269 ,  H05K3/0035 ,  H05K3/244 ,  H05K3/282 ,  H05K3/3452 ,  H05K3/3473 ,  H05K2201/0391 ,  H05K2201/09918 ,  H05K2203/054 ,  Y10T29/49149 ,  H01L2924/00

    摘要： A printed circuit board for use in a package and to a method of manufacturing the printed circuit board. The method of manufacturing the printed circuit board can include: providing a substrate, on one side of which at least one solder pad and at least one guide pad are formed; forming a solder resist layer over the one side of the substrate; uncovering at least one portion of the solder resist layer such that the guide pad is exposed; applying a surface treatment on the exposed guide pad; uncovering at least one portion of the solder resist layer such that the solder pad is exposed; and forming a solder bump on the exposed solder pad. With this method, the amount of surface treatment applied can be minimized, for reduced costs, and the occurrence of undiffused layers can be avoided, for improved reliability in the final product.

    摘要翻译： 一种用于封装的印刷电路板和制造印刷电路板的方法。 制造印刷电路板的方法可以包括：提供衬底，在衬底的一侧上形成至少一个焊盘和至少一个引导垫; 在衬底的一侧上形成阻焊层; 露出阻焊层的至少一部分，使得引导垫暴露; 在暴露的导向垫上进行表面处理; 露出阻焊层的至少一部分，使焊料焊盘露出; 并在暴露的焊盘上形成焊料凸块。 通过这种方法，可以最小化施加的表面处理量，从而降低成本，并且可以避免出现未扩散的层，从而提高最终产品的可靠性。