公开(公告)号：US09581588B2

公开(公告)日：2017-02-28

申请号：US14831734

申请日：2015-08-20

Applicant: Theranos, Inc.

Inventor： Tammy Burd ,  Ian Gibbons ,  Elizabeth A. Holmes ,  Gary Frenzel ,  Anthony Joseph Nugent

IPC: G01N33/00 ,  G01N33/53 ,  B01J19/00 ,  B01L3/00 ,  G01N35/02 ,  G01N1/38 ,  G01N33/569 ,  A61B5/15 ,  A61B5/151 ,  G01N35/10 ,  G01N33/68 ,  G01N33/94 ,  B01L7/00 ,  G01N33/543 ,  B01L3/02 ,  G01N35/00

CPC classification number: G01N33/5304 ,  A61B5/15 ,  A61B5/150755 ,  A61B5/151 ,  A61B10/0038 ,  A61B10/0045 ,  A61B10/0051 ,  A61B10/0058 ,  A61B10/007 ,  A61B10/02 ,  A61B2010/0074 ,  A61B2010/0077 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00292 ,  B01J2219/00315 ,  B01J2219/00369 ,  B01J2219/00371 ,  B01J2219/00385 ,  B01J2219/00466 ,  B01J2219/00495 ,  B01J2219/005 ,  B01J2219/00693 ,  B01J2219/00702 ,  B01L3/021 ,  B01L3/0262 ,  B01L3/5025 ,  B01L3/527 ,  B01L7/52 ,  B01L7/5255 ,  B01L9/543 ,  B01L2200/04 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2200/148 ,  B01L2300/0654 ,  B01L2300/0829 ,  B01L2300/1805 ,  B01L2400/043 ,  G01N1/38 ,  G01N33/5302 ,  G01N33/54326 ,  G01N33/54366 ,  G01N33/54386 ,  G01N33/56966 ,  G01N33/57484 ,  G01N33/6803 ,  G01N33/94 ,  G01N35/00732 ,  G01N35/00871 ,  G01N35/028 ,  G01N35/10 ,  G01N35/1065 ,  G01N35/1074 ,  G01N2035/00237 ,  G01N2035/00851 ,  G01N2035/00881 ,  G01N2035/0097 ,  G01N2035/1032 ,  G01N2035/1034 ,  G01N2035/1048 ,  G01N2333/4737 ,  G01N2333/475 ,  G01N2333/71 ,  G01N2333/912 ,  G01N2333/91205 ,  G01N2333/9129 ,  G01N2800/26 ,  G01N2800/60 ,  Y10T29/49826 ,  Y10T436/25375

Abstract: The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.

公开(公告)号：US20150368717A1

公开(公告)日：2015-12-24

申请号：US14789930

申请日：2015-07-01

Applicant: Theranos, Inc.

Inventor： Elizabeth A. Holmes ,  Sunny Balwani ,  Michael Chen ,  John K. Frankovich ,  Gary Frenzel ,  Surekha Gangakhedkar ,  Samartha Anekal ,  Adrit Lath ,  Alexander Loo ,  Chinmay Pangarkar ,  Paul Patel ,  Joy Roy ,  Timothy Smith ,  Daniel Young ,  Ian Gibbons

IPC: C12Q1/68 ,  B01L7/00 ,  C12Q1/70

CPC classification number: G01N35/0092 ,  B01L3/021 ,  B01L3/5082 ,  B01L3/50855 ,  B01L7/52 ,  B01L9/06 ,  B01L9/52 ,  B01L9/543 ,  B01L2300/1827 ,  B01L2300/1855 ,  C12Q1/42 ,  C12Q1/52 ,  C12Q1/6883 ,  C12Q1/70 ,  G01N15/1475 ,  G01N21/25 ,  G01N21/27 ,  G01N33/5005 ,  G01N33/54306 ,  G01N33/54313 ,  G01N33/54366 ,  G01N33/56983 ,  G01N33/62 ,  G01N33/6827 ,  G01N33/80 ,  G01N33/92 ,  G01N35/00 ,  G01N35/00029 ,  G01N35/00069 ,  G01N35/00623 ,  G01N35/00871 ,  G01N35/026 ,  G01N35/04 ,  G01N35/10 ,  G01N35/1009 ,  G01N35/1011 ,  G01N35/1065 ,  G01N35/1072 ,  G01N2015/0073 ,  G01N2015/008 ,  G01N2015/1006 ,  G01N2015/1486 ,  G01N2035/00138 ,  G01N2035/00148 ,  G01N2035/00237 ,  G01N2035/00306 ,  G01N2035/00326 ,  G01N2035/00356 ,  G01N2035/00366 ,  G01N2035/00425 ,  G01N2035/00435 ,  G01N2035/00495 ,  G01N2035/00633 ,  G01N2035/0449 ,  G01N2035/0474 ,  G01N2035/0486 ,  G01N2035/0491 ,  G01N2035/0493 ,  G01N2035/0494 ,  G01N2201/024 ,  G01N2201/04 ,  G01N2201/12 ,  Y10T436/111666 ,  Y10T436/113332

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

公开(公告)号：US20150338428A1

公开(公告)日：2015-11-26

申请号：US14789920

申请日：2015-07-01

Applicant: Theranos, Inc.

Inventor： Elizabeth A. Holmes ,  Sunny Balwani ,  Michael Chen ,  John K. Frankovich ,  Gary Frenzel ,  Surekha Gangakhedkar ,  Samartha Anekal ,  Adrit Lath ,  Alexander Loo ,  Chinmay Pangarkar ,  Paul Patel ,  Joy Roy ,  Timothy Smith ,  Daniel Young ,  Ian Gibbons

IPC: G01N35/02 ,  G01N35/10

CPC classification number: G01N35/0092 ,  B01L3/021 ,  B01L3/5082 ,  B01L3/50855 ,  B01L7/52 ,  B01L9/06 ,  B01L9/52 ,  B01L9/543 ,  B01L2300/1827 ,  B01L2300/1855 ,  C12Q1/42 ,  C12Q1/52 ,  C12Q1/6883 ,  C12Q1/70 ,  G01N15/1475 ,  G01N21/25 ,  G01N21/27 ,  G01N33/5005 ,  G01N33/54306 ,  G01N33/54313 ,  G01N33/54366 ,  G01N33/56983 ,  G01N33/62 ,  G01N33/6827 ,  G01N33/80 ,  G01N33/92 ,  G01N35/00 ,  G01N35/00029 ,  G01N35/00069 ,  G01N35/00623 ,  G01N35/00871 ,  G01N35/026 ,  G01N35/04 ,  G01N35/10 ,  G01N35/1009 ,  G01N35/1011 ,  G01N35/1065 ,  G01N35/1072 ,  G01N2015/0073 ,  G01N2015/008 ,  G01N2015/1006 ,  G01N2015/1486 ,  G01N2035/00138 ,  G01N2035/00148 ,  G01N2035/00237 ,  G01N2035/00306 ,  G01N2035/00326 ,  G01N2035/00356 ,  G01N2035/00366 ,  G01N2035/00425 ,  G01N2035/00435 ,  G01N2035/00495 ,  G01N2035/00633 ,  G01N2035/0449 ,  G01N2035/0474 ,  G01N2035/0486 ,  G01N2035/0491 ,  G01N2035/0493 ,  G01N2035/0494 ,  G01N2201/024 ,  G01N2201/04 ,  G01N2201/12 ,  Y10T436/111666 ,  Y10T436/113332

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

Abstract translation: 提供系统和方法用于样品处理。 可以提供能够接收样品并执行样品制备，样品测定和检测步骤中的一种或多种的装置。 该装置可能能够进行多个测定。 该装置可以包括一个或多个可以执行样品制备，样品测定和检测步骤中的一个或多个的模块。 该装置可以能够使用小体积的样品来执行步骤。

公开(公告)号：US09121851B2

公开(公告)日：2015-09-01

申请号：US13893258

申请日：2013-05-13

Applicant: Theranos, Inc.

Inventor： Tammy Burd ,  Ian Gibbons ,  Elizabeth A. Holmes ,  Gary Frenzel ,  Anthony Joseph Nugent

IPC: G01N33/00 ,  G01N33/569 ,  B01J19/00 ,  B01L3/00 ,  G01N35/02 ,  G01N33/543 ,  G01N33/53 ,  G01N1/38 ,  B01L7/00 ,  B01L3/02 ,  G01N35/00

CPC classification number: G01N33/5304 ,  A61B5/15 ,  A61B5/150755 ,  A61B5/151 ,  A61B10/0038 ,  A61B10/0045 ,  A61B10/0051 ,  A61B10/0058 ,  A61B10/007 ,  A61B10/02 ,  A61B2010/0074 ,  A61B2010/0077 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00292 ,  B01J2219/00315 ,  B01J2219/00369 ,  B01J2219/00371 ,  B01J2219/00385 ,  B01J2219/00466 ,  B01J2219/00495 ,  B01J2219/005 ,  B01J2219/00693 ,  B01J2219/00702 ,  B01L3/021 ,  B01L3/0262 ,  B01L3/5025 ,  B01L3/527 ,  B01L7/52 ,  B01L7/5255 ,  B01L9/543 ,  B01L2200/04 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2200/148 ,  B01L2300/0654 ,  B01L2300/0829 ,  B01L2300/1805 ,  B01L2400/043 ,  G01N1/38 ,  G01N33/5302 ,  G01N33/54326 ,  G01N33/54366 ,  G01N33/54386 ,  G01N33/56966 ,  G01N33/57484 ,  G01N33/6803 ,  G01N33/94 ,  G01N35/00732 ,  G01N35/00871 ,  G01N35/028 ,  G01N35/10 ,  G01N35/1065 ,  G01N35/1074 ,  G01N2035/00237 ,  G01N2035/00851 ,  G01N2035/00881 ,  G01N2035/0097 ,  G01N2035/1032 ,  G01N2035/1034 ,  G01N2035/1048 ,  G01N2333/4737 ,  G01N2333/475 ,  G01N2333/71 ,  G01N2333/912 ,  G01N2333/91205 ,  G01N2333/9129 ,  G01N2800/26 ,  G01N2800/60 ,  Y10T29/49826 ,  Y10T436/25375

Abstract: The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.

公开(公告)号：US09588109B2

公开(公告)日：2017-03-07

申请号：US15007585

申请日：2016-01-27

Applicant: Theranos, Inc.

Inventor： Tammy Burd ,  Ian Gibbons ,  Elizabeth A. Holmes ,  Gary Frenzel ,  Anthony Joseph Nugent

IPC: G01N33/00 ,  G01N33/53 ,  B01J19/00 ,  B01L3/00 ,  G01N35/02 ,  G01N1/38 ,  G01N33/569 ,  A61B5/15 ,  A61B5/151 ,  G01N35/10 ,  G01N33/68 ,  G01N33/94 ,  B01L7/00 ,  G01N33/543 ,  B01L3/02 ,  G01N35/00

CPC classification number: G01N33/5304 ,  A61B5/15 ,  A61B5/150755 ,  A61B5/151 ,  A61B10/0038 ,  A61B10/0045 ,  A61B10/0051 ,  A61B10/0058 ,  A61B10/007 ,  A61B10/02 ,  A61B2010/0074 ,  A61B2010/0077 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00292 ,  B01J2219/00315 ,  B01J2219/00369 ,  B01J2219/00371 ,  B01J2219/00385 ,  B01J2219/00466 ,  B01J2219/00495 ,  B01J2219/005 ,  B01J2219/00693 ,  B01J2219/00702 ,  B01L3/021 ,  B01L3/0262 ,  B01L3/5025 ,  B01L3/527 ,  B01L7/52 ,  B01L7/5255 ,  B01L9/543 ,  B01L2200/04 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2200/148 ,  B01L2300/0654 ,  B01L2300/0829 ,  B01L2300/1805 ,  B01L2400/043 ,  G01N1/38 ,  G01N33/5302 ,  G01N33/54326 ,  G01N33/54366 ,  G01N33/54386 ,  G01N33/56966 ,  G01N33/57484 ,  G01N33/6803 ,  G01N33/94 ,  G01N35/00732 ,  G01N35/00871 ,  G01N35/028 ,  G01N35/10 ,  G01N35/1065 ,  G01N35/1074 ,  G01N2035/00237 ,  G01N2035/00851 ,  G01N2035/00881 ,  G01N2035/0097 ,  G01N2035/1032 ,  G01N2035/1034 ,  G01N2035/1048 ,  G01N2333/4737 ,  G01N2333/475 ,  G01N2333/71 ,  G01N2333/912 ,  G01N2333/91205 ,  G01N2333/9129 ,  G01N2800/26 ,  G01N2800/60 ,  Y10T29/49826 ,  Y10T436/25375

Abstract: The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.

Abstract translation: 本发明提供了在护理点使用的装置和系统。 本发明的方法装置旨在自动检测体液中的分析物。 该装置的组件是模块化的，以允许与所公开的各种医疗应用的方法的灵活性和鲁棒性。

公开(公告)号：US20150377914A1

公开(公告)日：2015-12-31

申请号：US14848032

申请日：2015-09-08

Applicant: Theranos, Inc.

Inventor： Tammy Burd ,  Ian Gibbons ,  Elizabeth A. Holmes ,  Gary Frenzel ,  Anthony Joseph Nugent

IPC: G01N35/02 ,  G01N35/10 ,  G01N33/53

CPC classification number: G01N33/5304 ,  A61B5/15 ,  A61B5/150755 ,  A61B5/151 ,  A61B10/0038 ,  A61B10/0045 ,  A61B10/0051 ,  A61B10/0058 ,  A61B10/007 ,  A61B10/02 ,  A61B2010/0074 ,  A61B2010/0077 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00292 ,  B01J2219/00315 ,  B01J2219/00369 ,  B01J2219/00371 ,  B01J2219/00385 ,  B01J2219/00466 ,  B01J2219/00495 ,  B01J2219/005 ,  B01J2219/00693 ,  B01J2219/00702 ,  B01L3/021 ,  B01L3/0262 ,  B01L3/5025 ,  B01L3/527 ,  B01L7/52 ,  B01L7/5255 ,  B01L9/543 ,  B01L2200/04 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2200/148 ,  B01L2300/0654 ,  B01L2300/0829 ,  B01L2300/1805 ,  B01L2400/043 ,  G01N1/38 ,  G01N33/5302 ,  G01N33/54326 ,  G01N33/54366 ,  G01N33/54386 ,  G01N33/56966 ,  G01N33/57484 ,  G01N33/6803 ,  G01N33/94 ,  G01N35/00732 ,  G01N35/00871 ,  G01N35/028 ,  G01N35/10 ,  G01N35/1065 ,  G01N35/1074 ,  G01N2035/00237 ,  G01N2035/00851 ,  G01N2035/00881 ,  G01N2035/0097 ,  G01N2035/1032 ,  G01N2035/1034 ,  G01N2035/1048 ,  G01N2333/4737 ,  G01N2333/475 ,  G01N2333/71 ,  G01N2333/912 ,  G01N2333/91205 ,  G01N2333/9129 ,  G01N2800/26 ,  G01N2800/60 ,  G16H10/40 ,  Y10T29/49826 ,  Y10T436/25375

Abstract: The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.

公开(公告)号：US09012163B2

公开(公告)日：2015-04-21

申请号：US14339946

申请日：2014-07-24

Applicant: Theranos, Inc.

Inventor： Tammy Burd ,  Ian Gibbons ,  Elizabeth A. Holmes ,  Gary Frenzel ,  Anthony Joseph Nugent

IPC: G01N33/00 ,  G01N33/569 ,  B01J19/00 ,  B01L3/00 ,  G01N35/02 ,  G01N33/543 ,  G01N33/53 ,  G01N1/38 ,  B01L3/02 ,  G01N35/00

CPC classification number: G01N33/5304 ,  A61B5/15 ,  A61B5/150755 ,  A61B5/151 ,  A61B10/0038 ,  A61B10/0045 ,  A61B10/0051 ,  A61B10/0058 ,  A61B10/007 ,  A61B10/02 ,  A61B2010/0074 ,  A61B2010/0077 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00292 ,  B01J2219/00315 ,  B01J2219/00369 ,  B01J2219/00371 ,  B01J2219/00385 ,  B01J2219/00466 ,  B01J2219/00495 ,  B01J2219/005 ,  B01J2219/00693 ,  B01J2219/00702 ,  B01L3/021 ,  B01L3/0262 ,  B01L3/5025 ,  B01L3/527 ,  B01L7/52 ,  B01L7/5255 ,  B01L9/543 ,  B01L2200/04 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2200/148 ,  B01L2300/0654 ,  B01L2300/0829 ,  B01L2300/1805 ,  B01L2400/043 ,  G01N1/38 ,  G01N33/5302 ,  G01N33/54326 ,  G01N33/54366 ,  G01N33/54386 ,  G01N33/56966 ,  G01N33/57484 ,  G01N33/6803 ,  G01N33/94 ,  G01N35/00732 ,  G01N35/00871 ,  G01N35/028 ,  G01N35/10 ,  G01N35/1065 ,  G01N35/1074 ,  G01N2035/00237 ,  G01N2035/00851 ,  G01N2035/00881 ,  G01N2035/0097 ,  G01N2035/1032 ,  G01N2035/1034 ,  G01N2035/1048 ,  G01N2333/4737 ,  G01N2333/475 ,  G01N2333/71 ,  G01N2333/912 ,  G01N2333/91205 ,  G01N2333/9129 ,  G01N2800/26 ,  G01N2800/60 ,  Y10T29/49826 ,  Y10T436/25375

Abstract: The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.

Abstract translation: 本发明提供了在护理点使用的装置和系统。 本发明的方法装置旨在自动检测体液中的分析物。 该装置的组件是模块化的，以允许与所公开的各种医疗应用的方法的灵活性和鲁棒性。

公开(公告)号：US20140335506A1

公开(公告)日：2014-11-13

申请号：US14339946

申请日：2014-07-24

Applicant: Theranos, Inc.

Inventor： Tammy Burd ,  Ian Gibbons ,  Elizabeth A. Holmes ,  Gary Frenzel ,  Anthony Joseph Nugent

IPC: G01N33/569

CPC classification number: G01N33/5304 ,  A61B5/15 ,  A61B5/150755 ,  A61B5/151 ,  A61B10/0038 ,  A61B10/0045 ,  A61B10/0051 ,  A61B10/0058 ,  A61B10/007 ,  A61B10/02 ,  A61B2010/0074 ,  A61B2010/0077 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00292 ,  B01J2219/00315 ,  B01J2219/00369 ,  B01J2219/00371 ,  B01J2219/00385 ,  B01J2219/00466 ,  B01J2219/00495 ,  B01J2219/005 ,  B01J2219/00693 ,  B01J2219/00702 ,  B01L3/021 ,  B01L3/0262 ,  B01L3/5025 ,  B01L3/527 ,  B01L7/52 ,  B01L7/5255 ,  B01L9/543 ,  B01L2200/04 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2200/148 ,  B01L2300/0654 ,  B01L2300/0829 ,  B01L2300/1805 ,  B01L2400/043 ,  G01N1/38 ,  G01N33/5302 ,  G01N33/54326 ,  G01N33/54366 ,  G01N33/54386 ,  G01N33/56966 ,  G01N33/57484 ,  G01N33/6803 ,  G01N33/94 ,  G01N35/00732 ,  G01N35/00871 ,  G01N35/028 ,  G01N35/10 ,  G01N35/1065 ,  G01N35/1074 ,  G01N2035/00237 ,  G01N2035/00851 ,  G01N2035/00881 ,  G01N2035/0097 ,  G01N2035/1032 ,  G01N2035/1034 ,  G01N2035/1048 ,  G01N2333/4737 ,  G01N2333/475 ,  G01N2333/71 ,  G01N2333/912 ,  G01N2333/91205 ,  G01N2333/9129 ,  G01N2800/26 ,  G01N2800/60 ,  Y10T29/49826 ,  Y10T436/25375

Abstract: The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.

Abstract translation: 本发明提供了在护理点使用的装置和系统。 本发明的方法装置旨在自动检测体液中的分析物。 该装置的组件是模块化的，以允许与所公开的各种医疗应用的方法的灵活性和鲁棒性。

公开(公告)号：US20140308661A1

公开(公告)日：2014-10-16

申请号：US14183503

申请日：2014-02-18

Applicant: Theranos, Inc.

Inventor： Elizabeth A. Holmes ,  Sunny Balwani ,  Michael Chen ,  John K. Frankovich ,  Gary Frenzel ,  Surekha Gangakhedkar ,  Samartha Anekal ,  Adrit Lath ,  Alexander Loo ,  Chinmay Pangarkar ,  Paul Patel ,  Joy Roy ,  Timothy Smith ,  Daniel Young ,  Ian Gibbons

IPC: G01N21/64

CPC classification number: G01N35/0092 ,  G01N21/25 ,  G01N21/6428 ,  G01N35/00 ,  G01N35/00732 ,  G01N2015/1006 ,  G01N2035/00326 ,  G01N2035/00495 ,  G01N2035/00811 ,  G01N2035/0094

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

公开(公告)号：US09623411B1

公开(公告)日：2017-04-18

申请号：US14309877

申请日：2014-06-19

Applicant: Theranos, Inc.

Inventor： Gary Frenzel ,  Samartha Anekal ,  Daniel Young

IPC: B01L3/00

CPC classification number: B01L3/527 ,  B01F11/0065 ,  B01F11/0074 ,  B01L2200/026 ,  B01L2200/0684 ,  B01L2300/0858 ,  B01L2300/123 ,  B01L2400/0406

Abstract: In one embodiment described herein, a cartridge is provided comprising a cartridge frame; a plurality of diluents each in an expandable container; a plurality of reagents each in an expandable container; and a plurality of mixing vessels comprising empty expandable containers.