EVALUATING ASSAYS WHICH OPTICAL INHOMOGENEITIES
    9.
    发明申请
    EVALUATING ASSAYS WHICH OPTICAL INHOMOGENEITIES 审中-公开
    评估光学不均匀性的测定

    公开(公告)号:US20140051187A1

    公开(公告)日:2014-02-20

    申请号:US14113964

    申请日:2012-04-23

    IPC分类号: G01N21/00

    摘要: The invention relates to a method and a sensor device (100) for evaluating an assay with a sample. During the assay, optical measurements are made at a sensing surface (112), and at least one “homogeneity-image” of the sensing surface (112) is generated. From this image, an “homogeneity-indicator” is determined for at least one region of interest, and the optical measurements are then evaluated in dependence on said indicator. The homogeneity-indicator may for example be a binary value which indicates if an inhomogeneity was detected or not. If an inhomogeneity was detected, all optical measurements may be rejected, only measurements for the involved region of interest may be rejected, or measurements for a selected sub-area of the involved region of interest(ROI) may be rejected.

    摘要翻译: 本发明涉及用于评价样品的测定方法和传感器装置(100)。 在测定期间,在感测表面(112)处进行光学测量,并且产生感测表面(112)的至少一个“均匀性图像”。 从该图像中,对于至少一个感兴趣的区域确定“均匀度指标”,然后根据所述指标来评估光学测量。 均匀度指示符可以例如是二进制值,其指示是否检测到不均匀性。 如果检测到不均匀性,则所有光学测量可能被拒绝,只有感兴趣区域的测量可能被拒绝,或者所涉及的感兴趣区域(ROI)的选定子区域的测量可能被拒绝。

    SYSTEM FOR SELECTIVELY PROCEEDING A SAMPLE
    10.
    发明申请
    SYSTEM FOR SELECTIVELY PROCEEDING A SAMPLE 审中-公开
    选择一个样品的系统

    公开(公告)号:US20130109106A1

    公开(公告)日:2013-05-02

    申请号:US13808522

    申请日:2011-07-04

    IPC分类号: G01N1/10

    摘要: The invention relates to a method and a system (100) for selectively processing a sample (130) according to one of a plurality of different assays, for example for detecting a certain target component in the sample. The system comprises a plurality of “specific reagent reservoirs” (120) that contain different sets of reagents, wherein each set is required for one of the assays. Moreover, the system (100) comprises a “universal reagent reservoir” in which reagents for several assays are provided, preferably reagents for all assays. The universal reagent reservoir may preferably be a cartridge (110) in which the processing of a sample (130) can take place and which comprises a plurality of binding sites that are selective for different target components. Depending on the assay to be performed with a sample (130) at hand, the appropriate specific reagent reservoir (121b) is chosen and processed in the universal cartridge (110). This can particularly be done by a manipulator (140) in a high-throughput automated laboratory system.

    摘要翻译: 本发明涉及用于根据多种不同测定中的一种选择性处理样品(130)的方法和系统(100),例如用于检测样品中某一目标成分。 该系统包括多个含有不同试剂组的“特异性试剂储存器”(120),其中每种试剂均需要每组。 此外,系统(100)包括“通用试剂储库”,其中提供用于几种测定的试剂,优选用于所有测定的试剂。 通用试剂储存器可以优选地是其中样品(130)的处理可以发生并且包括对不同目标组分具有选择性的多个结合位点的盒(110)。 根据将要用手的样品(130)进行的测定,在通用盒(110)中选择并处理适当的特定试剂储存器(121b)。 这可以通过高通量自动化实验室系统中的机械手(140)来进行。