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    Multi-layer structure having a predetermined layer pattern including an agent
    1.
    发明申请
    Multi-layer structure having a predetermined layer pattern including an agent 审中-公开
    具有包括试剂的预定层图案的多层结构

    公开(公告)号：US20060269475A1

    公开(公告)日：2006-11-30

    申请号：US11402651

    申请日：2006-04-11

    申请人： WonHyoung Ryu ,  Rainer Fasching ,  Friedrich Prinz ,  Ralph Greco

    发明人： WonHyoung Ryu ,  Rainer Fasching ,  Friedrich Prinz ,  Ralph Greco

    IPC分类号： A61K51/00 ,  A61K9/14

    CPC分类号： A61K9/0097 ,  A61K9/0004 ,  A61K9/0024 ,  A61K9/0051 ,  A61K9/2072 ,  A61K51/1282

    摘要： Improved controlled therapy is provided with a polymer multi-layer structure having a predetermined micro-fabricated spatial pattern (e.g., reservoirs and channels). More specifically, all geometrical details of the spatial pattern are substantially predetermined. The increased control of pattern geometry provided by the invention allows for improved control of therapy. In preferred embodiments, the polymer multi-layer structure of the invention is biodegradable, but has an in vivo lifetime that is greater than the duration of the therapy being provided. Thus, the geometrical pattern of the polymer structure that controls delivery of the therapy persists without significant change during therapy, and the structure degrades after completion of therapy. In this manner, possible interference of degradation by-products with therapy is minimized, and delivery of therapy does not depend on details of how degradation proceeds.

    摘要翻译： 提供了具有预定的微制造空间图案（例如储存器和通道）的聚合物多层结构的改进的对照治疗。 更具体地，空间图案的所有几何细节基本上是预先确定的。 由本发明提供的图案几何形状的增加的控制允许改善治疗的控制。 在优选的实施方案中，本发明的聚合物多层结构是可生物降解的，但是具有比所提供的治疗持续时间更长的体内寿命。 因此，控制治疗递送的聚合物结构的几何图案在治疗期间持续而没有显着变化，并且结构在治疗完成后降解。 以这种方式，降解副产物与治疗的可能干扰被最小化，并且治疗的递送不依赖于如何降解进行的细节。

    Wound Closure Devices, Methods of Use, and Kits
    5.
    发明申请
    Wound Closure Devices, Methods of Use, and Kits 审中-公开
    伤口闭合装置，使用方法和试剂盒

    公开(公告)号：US20090227938A1

    公开(公告)日：2009-09-10

    申请号：US12247003

    申请日：2008-10-07

    申请人： Rainer Fasching ,  WonHyoung Ryu ,  Darius Moshfeghi

    发明人： Rainer Fasching ,  WonHyoung Ryu ,  Darius Moshfeghi

    IPC分类号： A61F9/007

    CPC分类号： A61B17/0057 ,  A61B17/068 ,  A61B2017/00654 ,  A61B2017/0647 ,  A61F9/0017 ,  A61F9/00736

    摘要： Provided herein is a wound closure device comprising a plug adaptable to be inserted into an opening formed in two or more tissue layers, one tissue layer transposable relative to a second layer, the plug comprising a material having a first configuration and a second configuration, wherein the plug is adaptable to be inserted into the opening in the first configuration and further adaptable to transition from the first configuration to the second configuration after being inserted into the opening. The wound closure device can be used in cases where ocular surgery has been preformed.

    摘要翻译： 本文提供了一种伤口闭合装置，其包括适于插入形成在两个或更多个组织层中的开口的插塞，相对于第二层可转座的一个组织层，所述插塞包括具有第一构型和第二构型的材料，其中 插头适于在第一构造中插入到开口中，并且在插入到开口中之后还可适应于从第一构型转变到第二构造。 伤口闭合装置可用于进行眼外科手术的情况。

    Membrane electrode assembly in solid oxide fuel cells
    6.
    发明申请
    Membrane electrode assembly in solid oxide fuel cells 审中-公开
    固体氧化物燃料电池中的膜电极组件

    公开(公告)号：US20070184322A1

    公开(公告)日：2007-08-09

    申请号：US11655460

    申请日：2007-01-18

    申请人： Hong Huang ,  Pei-Chen Su ,  Friedrich Prinz ,  Masafumi Nakamura ,  Timothy Holme ,  Rainer Fasching ,  Yuji Saito

    发明人： Hong Huang ,  Pei-Chen Su ,  Friedrich Prinz ,  Masafumi Nakamura ,  Timothy Holme ,  Rainer Fasching ,  Yuji Saito

    IPC分类号： H01M8/12 ,  H01M8/02 ,  B05D5/12

    CPC分类号： H01M8/1213 ,  H01M4/8642 ,  H01M4/8657 ,  H01M4/8885 ,  H01M8/122 ,  H01M8/1226 ,  H01M8/1246 ,  H01M8/1286 ,  H01M8/2425 ,  H01M2008/1293 ,  H01M2300/0094 ,  Y02E60/525 ,  Y02P70/56

    摘要： A membrane-electrode assembly for a solid oxide fuel cell is provided. The membrane-electrode assembly has a substantially constant-thickness electrolyte layer. The electrolyte layer distinguishes first and second electrolyte layer surfaces arranged in a three-dimensional pattern with opposite first and second planar pattern surfaces. The three-dimensional pattern has a first set of features extending inward from the first planar pattern surface. It has a second set of features extending inward from the second planar pattern surface opposite to the first planar pattern surface. A first electrode layer is adjacent and conforming to the first electrolyte layer surface. At least one mechanical support structure exists within some or all of the second set of features. A second electrode layer is adjacent and conforming to the second electrolyte layer surface and to at least one mechanical support structure. The membrane-electrode assembly is deposited on a substrate with at least one through hole.

    摘要翻译： 提供了一种用于固体氧化物燃料电池的膜 - 电极组件。 膜 - 电极组件具有基本恒定的电解质层。 电解质层将以三维图案排列的第一和第二电解质层表面与相对的第一和第二平面图案表面区分开。 三维图案具有从第一平面图案表面向内延伸的第一组特征。 它具有从与第一平面图案表面相对的第二平面图形表面向内延伸的第二组特征。 第一电极层相邻并且与第一电解质层表面一致。 在第二组特征的一些或全部内存在至少一个机械支撑结构。 第二电极层与第二电解质层表面相邻并且与至少一个机械支撑结构相符。 膜 - 电极组件被沉积在具有至少一个通孔的基底上。

    INTERCONNECTING ELECTROCHEMICALLY ACTIVE MATERIAL NANOSTRUCTURES
    9.
    发明申请
    INTERCONNECTING ELECTROCHEMICALLY ACTIVE MATERIAL NANOSTRUCTURES 审中-公开
    互连电化学活性材料纳米结构

    公开(公告)号：US20110229761A1

    公开(公告)日：2011-09-22

    申请号：US13069212

    申请日：2011-03-22

    申请人： Yi Cui ,  Song Han ,  Ghyrn E. Loveness ,  Rainer Fasching ,  William S. DelHagen ,  Eugene M. Berdichevsky

    发明人： Yi Cui ,  Song Han ,  Ghyrn E. Loveness ,  Rainer Fasching ,  William S. DelHagen ,  Eugene M. Berdichevsky

    IPC分类号： H01M4/58 ,  B05D5/12

    CPC分类号： H01M4/386 ,  H01M4/134 ,  H01M4/1395 ,  H01M4/366 ,  H01M4/38 ,  H01M4/387 ,  H01M4/626

    摘要： Provided are various examples of lithium electrode subassemblies, lithium ion cells using such subassemblies, and methods of fabricating such subassemblies. Methods generally include receiving nanostructures containing electrochemically active materials and interconnecting at least a portion of these nanostructures. Interconnecting may involve depositing one or more interconnecting materials, such as amorphous silicon and/or metal containing materials. Interconnecting may additionally or alternatively involve treating a layer containing the nanostructures using various techniques, such as compressing the layer, heating the layer, and/or passing an electrical current through the layer. These methods may be used to interconnect nanostructures containing one or more high capacity materials, such as silicon, germanium, and tin, and having various shapes or forms, such as nanowires, nanoparticles, and nano-flakes.

    摘要翻译： 提供了锂电极子组件的各种示例，使用这种组件的锂离子电池以及制造这种组件的方法。 方法通常包括接收含有电化学活性材料的纳米结构并互连这些纳米结构的至少一部分。 互连可以涉及沉积一种或多种互连材料，例如非晶硅和/或含金属的材料。 互连可以另外或替代地涉及使用各种技术处理包含纳米结构的层，例如压缩层，加热层和/或使电流通过层。 这些方法可以用于连接含有一种或多种高容量材料（例如硅，锗和锡）的纳米结构，并且具有各种形状或形式，例如纳米线，纳米颗粒和纳米薄片。