公开(公告)号：US12084554B2

公开(公告)日：2024-09-10

申请号：US18464836

申请日：2023-09-11

Applicant: Simon Fraser University

Inventor： Steven Holdcroft ,  Thomas J. G. Skalski ,  Michael Adamski ,  Benjamin Britton ,  Timothy J. Peckham

IPC: C08J5/22 ,  B01D69/02 ,  B01D71/82 ,  C07C211/63 ,  C07C309/44 ,  C08G61/10 ,  H01M8/10 ,  H01M8/1023

CPC classification number: C08J5/2256 ,  B01D69/02 ,  B01D71/82 ,  C07C211/63 ,  C07C309/44 ,  C08G61/10 ,  H01M8/1023 ,  B01D2325/42 ,  C08G2261/11 ,  C08G2261/1452 ,  C08G2261/148 ,  C08G2261/228 ,  C08G2261/312 ,  C08J2365/02 ,  H01M2008/1095

Abstract: Described herein are anionic phenylene oligomers and polymers, and devices including these materials. The oligomers and polymers can be prepared in a convenient and well-controlled manner, and can be used in cation exchange membranes. Also described is the controlled synthesis of anionic phenylene monomers and their use in synthesizing anionic oligomers and polymers, with precise control of the position and number of anionic groups.

公开(公告)号：US20210020943A1

公开(公告)日：2021-01-21

申请号：US16968732

申请日：2019-02-13

Applicant: CMBLU PROJEKT AG

Inventor： Jan HARTWIG ,  Peter GEIGLE ,  Evgeny LARIONOV

IPC: H01M4/60 ,  H01M8/18 ,  H01M8/04186 ,  H01M4/36 ,  C07G1/00 ,  C07C309/14 ,  C07C39/24 ,  C07C309/42 ,  C07C215/50 ,  C07C309/44

Abstract: The present invention relates to novel combinations of redox active compounds for use as redox flow battery electrolytes. The invention further provides kits comprising these combinations, redox flow batteries, and method using the combinations, kits and redox flow batteries of the invention.

公开(公告)号：US10562837B2

公开(公告)日：2020-02-18

申请号：US16064287

申请日：2016-12-22

Applicant: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO

Inventor： Marc Crockatt ,  Jan Harm Urbanus ,  Paul Mathijs Könst

IPC: C07D307/00 ,  C07C67/31 ,  C07C37/50 ,  C07C309/42 ,  C07C309/58 ,  C07C51/09 ,  C07C309/32 ,  C07C303/22 ,  C07C309/44 ,  C07C309/75 ,  C07C309/77

Abstract: The invention relates to a method for preparing a compound comprising two phenyl groups by reacting a bisfuranic compound with a dienophile; and to such compounds.

公开(公告)号：US09553326B2

公开(公告)日：2017-01-24

申请号：US14843695

申请日：2015-09-02

Applicant: TORAY INDUSTRIES, INC.

Inventor： Daisuke Izuhara ,  Hiroaki Umeda ,  Emi Amano ,  Tomoyuki Kunita

IPC: C08G75/24 ,  C08G65/40 ,  C07C317/22 ,  H01B1/12 ,  C07C309/60 ,  H01M8/10 ,  C07C309/44 ,  H01B1/06 ,  H01M4/86 ,  H01M8/02

CPC classification number: H01M8/1032 ,  C07C309/44 ,  C07C309/60 ,  C07C317/22 ,  C08G65/40 ,  C08G65/4012 ,  C08G65/4056 ,  C08G2650/40 ,  H01B1/122 ,  H01M8/1025 ,  H01M8/1027 ,  H01M8/1039 ,  H01M2008/1095 ,  H01M2300/0082 ,  Y02E60/521

Abstract: Provided are an aromatic sulfonic acid derivative and a sulfonic acid group-containing polymer, each of which has excellent proton conductivity even under low humidification conditions, while having excellent mechanical strength and chemical stability, and enables a solid polymer fuel cell to achieve high output and excellent physical durability when used therein. This aromatic sulfonic acid derivative has a specific structure and is characterized in that a sulfonic acid group is introduced into more than 50% of all the phenyl groups. This sulfonic acid group-containing polymer is characterized by being obtained by polymerization using the aromatic sulfonic acid derivative, and is also characterized by having a specific structure.

Abstract translation: 提供了即使在低加湿条件下也具有优异的质子传导性的芳香族磺​​酸衍生物和含磺酸基的聚合物，同时具有优异的机械强度和化学稳定性，并且能够使固体高分子型燃料电池实现高输出， 使用时具有良好的物理耐久性。 该芳香族磺酸衍生物具有特定的结构，其特征在于，在全部苯基的50％以上引入磺酸基。 该含磺酸基的聚合物的特征在于通过使用芳香族磺酸衍生物的聚合得到，特征在于具有特定的结构。

公开(公告)号：US20160333033A1

公开(公告)日：2016-11-17

申请号：US15218738

申请日：2016-07-25

Applicant: Sun Yat-Sen University

Inventor： Xianzhang Bu ,  Cuige Zhu ,  Xin Yue ,  Yinglin Zuo ,  Yu Chen ,  Gesi Wen

IPC: C07F9/12 ,  C07C225/22 ,  C07C221/00 ,  C07C49/84 ,  C07C45/45 ,  C07C303/22 ,  C07C255/56 ,  C07C253/30 ,  C07D207/08 ,  C07C65/38 ,  C07C51/347 ,  C07C309/44 ,  C07F5/02 ,  C07C49/835

CPC classification number: C07F9/12 ,  C07C45/45 ,  C07C45/63 ,  C07C49/248 ,  C07C49/255 ,  C07C49/835 ,  C07C49/84 ,  C07C51/347 ,  C07C51/373 ,  C07C65/38 ,  C07C221/00 ,  C07C225/22 ,  C07C253/30 ,  C07C255/56 ,  C07C303/22 ,  C07C309/44 ,  C07D207/08 ,  C07D295/112 ,  C07D295/12 ,  C07F5/025 ,  C07C49/813

Abstract: Disclosed are an o-phenyl chalcone compounds and preparation methods and uses thereof. The o-phenyl chalcone compounds are capable of inhibiting the aggregation of microtubules in tumor cells and influencing the mitosis of the cells, and have a high antitumor activity. The compounds also have inhibitory activity against proliferation on various tumor cells, such as a human ovary cancer cell A2780, a human colon cancer cell HCT8, a human breast cancer cell MCF7, a human lung cancer cell A549, a human colon cancer cell SW480, a human nasopharyngeal carcinoma cell CNE2, a human liver cancer cell HepG2 and the like at nanomole concentrations.

Abstract translation: 公开了邻苯基查耳酮化合物及其制备方法和用途。 邻苯基查耳酮化合物能够抑制肿瘤细胞中微管的聚集并影响细胞的有丝分裂，并且具有高的抗肿瘤活性。 该化合物还具有抑制各种肿瘤细胞增殖的作用，例如人卵巢癌细胞A2780，人结肠癌细胞HCT8，人乳腺癌细胞MCF7，人肺癌细胞A549，人结肠癌细胞SW480， 人鼻咽癌细胞CNE2，人肝癌细胞HepG2等纳米摩尔浓度。

公开(公告)号：US20150380759A1

公开(公告)日：2015-12-31

申请号：US14843695

申请日：2015-09-02

Applicant: TORAY INDUSTRIES, INC.

Inventor： Daisuke IZUHARA ,  Hiroaki UMEDA ,  Emi AMANO ,  Tomoyuki KUNITA

IPC: H01M8/10 ,  C07C317/22 ,  C07C309/44

CPC classification number: H01M8/1032 ,  C07C309/44 ,  C07C309/60 ,  C07C317/22 ,  C08G65/40 ,  C08G65/4012 ,  C08G65/4056 ,  C08G2650/40 ,  H01B1/122 ,  H01M8/1025 ,  H01M8/1027 ,  H01M8/1039 ,  H01M2008/1095 ,  H01M2300/0082 ,  Y02E60/521

Abstract: Provided are an aromatic sulfonic acid derivative and a sulfonic acid group-containing polymer, each of which has excellent proton conductivity even under low humidification conditions, while having excellent mechanical strength and chemical stability, and enables a solid polymer fuel cell to achieve high output and excellent physical durability when used therein. This aromatic sulfonic acid derivative has a specific structure and is characterized in that a sulfonic acid group is introduced into more than 50% of all the phenyl groups. This sulfonic acid group-containing polymer is characterized by being obtained by polymerization using the aromatic sulfonic acid derivative, and is also characterized by having a specific structure.

Abstract translation: 提供了即使在低加湿条件下也具有优异的质子传导性的芳香族磺​​酸衍生物和含磺酸基的聚合物，同时具有优异的机械强度和化学稳定性，并且能够使固体高分子型燃料电池实现高输出， 使用时具有良好的物理耐久性。 该芳香族磺酸衍生物具有特定的结构，其特征在于，在全部苯基的50％以上引入磺酸基。 该含磺酸基的聚合物的特征在于通过使用芳香族磺酸衍生物的聚合得到，特征在于具有特定的结构。

公开(公告)号：US09120725B2

公开(公告)日：2015-09-01

申请号：US13812894

申请日：2011-07-06

Applicant: Milan Fedurco

Inventor： Milan Fedurco

IPC: C07C309/44 ,  C07C49/825 ,  C07C49/813 ,  C07C49/83 ,  H01M8/10 ,  C08G65/40 ,  C08L71/00 ,  B01D71/66 ,  C07C49/80 ,  C08G75/02

CPC classification number: C07C309/44 ,  B01D71/66 ,  C07C49/80 ,  C07C49/813 ,  C07C49/825 ,  C07C49/83 ,  C08G65/4025 ,  C08G75/02 ,  C08G2650/40 ,  C08L71/00 ,  H01M8/1025 ,  H01M8/1039 ,  H01M8/1088 ,  Y02E60/521 ,  Y02P70/56

Abstract: An aromatic perfluoroalkane monomer is provided that can be used for the manufacture of a polymer membrane for a PEM-type fuel cell. The perfluoroalkane monomer has a structure corresponding to a formula (I): Z1—Ar3—C(O)—Ar1—(CF2)n—Ar2—C(O)—Ar4—Z2  (I) in which: n is in a range from 1 to 20; Ar1, Ar2, Ar3, Ar4 which are identical or different, represent a substituted or unsubstituted phenylene group; and Z1 and Z2, which are identical or different, represent an electrophilic or nucleophilic polymerizable functional group.

Abstract translation: 提供了可用于制造用于PEM型燃料电池的聚合物膜的芳族全氟烷烃单体。 全氟烷基单体具有对应于式（I）的结构：Z1-Ar3-C（O）-Ar1-（CF2）n-Ar2-C（O）-Ar4-Z2（Ⅰ），其中n为 范围从1到20; 相同或不同的Ar 1，Ar 2，Ar 3，Ar 4表示取代或未取代的亚苯基; 和相同或不同的Z 1和Z 2表示亲电或亲核可聚合官能团。

公开(公告)号：US20150004699A1

公开(公告)日：2015-01-01

申请号：US14483080

申请日：2014-09-10

Applicant: Baylor College of Medicine

Inventor： Changyi Chen ,  Jian-Ming Lu ,  Qizhi Yao

IPC: C07C47/54 ,  C07C313/04 ,  C07C309/44 ,  C07C205/44 ,  C07C255/56

CPC classification number: A61K31/11 ,  A61K9/0053 ,  A61K31/185 ,  A61K31/277 ,  A61K31/519 ,  A61K45/06 ,  C07C47/54 ,  C07C47/544 ,  C07C47/565 ,  C07C205/44 ,  C07C255/56 ,  C07C255/57 ,  C07C309/44 ,  C07C313/04 ,  C07C317/22

Abstract: Small molecule xanthine oxidase inhibitors are provided, as well as methods for their use in treating gout or hyperuricemia.

Abstract translation: 提供了小分子黄嘌呤氧化酶抑制剂，以及它们用于治疗痛风或高尿酸血症的方法。

公开(公告)号：US20140336258A1

公开(公告)日：2014-11-13

申请号：US14445713

申请日：2014-07-29

Applicant: Case Western Reserve University

Inventor： Menachem Shoham

IPC: C07C49/83 ,  A61K31/12 ,  A61K31/192 ,  C07C309/44 ,  A61K31/185 ,  C07C65/24 ,  C07C49/84 ,  A61K45/06

CPC classification number: C07C49/83 ,  A61K31/12 ,  A61K31/166 ,  A61K31/185 ,  A61K31/192 ,  A61K31/36 ,  A61K31/404 ,  A61K45/06 ,  C07C49/84 ,  C07C65/24 ,  C07C309/44 ,  C07C2601/16 ,  C12N1/36

Abstract: A method of reducing the virulence of a bacterium that expresses accessory gene regulator A (AgrA) includes administering to the bacterium an amount of AgrA antagonist effective to inhibit the synthesis of one or more virulence factors by the bacterium.

Abstract translation: 降低表达附属基因调节剂A（AgrA）的细菌的毒力的方法包括向细菌施用一定量的有效抑制细菌合成一种或多种毒力因子的AgrA拮抗剂。

公开(公告)号：US08853441B2

公开(公告)日：2014-10-07

申请号：US13557893

申请日：2012-07-25

Applicant: Jung Hoon Oh ,  Dae Kyung Yoon ,  Seung Duk Cho ,  So Jeong Park

Inventor： Jung Hoon Oh ,  Dae Kyung Yoon ,  Seung Duk Cho ,  So Jeong Park

IPC: C07C69/013 ,  C07C69/017 ,  C07C309/02 ,  C07C309/39 ,  C07C309/44 ,  C07C381/12 ,  G03F7/00 ,  C07C309/12 ,  G03F7/004 ,  C07D333/46 ,  C07C309/06 ,  C07D307/64 ,  G03C1/00 ,  G03F7/039

CPC classification number: C07C309/06 ,  C07C309/02 ,  C07C309/12 ,  C07C381/12 ,  C07C2602/42 ,  C07C2603/74 ,  C07D307/64 ,  C07D333/46 ,  G03F7/00 ,  G03F7/004 ,  G03F7/0045 ,  G03F7/0046 ,  G03F7/0395 ,  G03F7/0397

Abstract: A sulfonium compound represented by the following formula (1), a photoacid generator containing the sulfonium compound, and a resist composition containing the photoacid generator are provided: wherein X represents an electron donor group; R1 and R2 each independently represent an alkyl group or the like; R4 to R6 each independently represent an alkyl group, or the like; R3 represents a cyclic alkenediyl group or the like; and −A represents an anion. The sulfonium compound has a photon yield that is controllable by introducing different absorbers to the cation region in one molecule, can address the inconvenience of using a mixture of different photoacid generators when the sulfonium compound is applied as a photoacid generator, has excellent miscibility in a resist, and has enhanced resolution and line edge roughness.

Abstract translation: 提供由下式（1）表示的锍化合物，含有锍化合物的光酸产生剂和含有光酸产生剂的抗蚀剂组合物，其中X表示电子给体基团; R1和R2各自独立地表示烷基等; R4至R6各自独立地表示烷基等; R3表示环状亚烯基等; -A表示阴离子。 锍化合物具有通过在一个分子中向阳离子区域引入不同吸收剂可控制的光子产率，可以解决当将锍化合物用作光致酸发生剂时使用不同光酸产生剂的混合物的不便之处，在 抗蚀，并具有增强的分辨率和线边缘粗糙度。