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公开(公告)号:US20050160824A1
公开(公告)日:2005-07-28
申请号:US11025793
申请日:2004-12-28
申请人: Mark Zdeblick , Benedict Costello
发明人: Mark Zdeblick , Benedict Costello
IPC分类号: A61B20060101 , A61B5/0215 , A61N1/362 , A61N1/365 , G01L9/00 , G01L9/04 , G01L9/06 , H01L21/44 , H01L21/48
CPC分类号: A61B5/0215 , A61B5/412 , A61B2562/02 , A61N1/3627 , A61N1/36564 , G01L9/0042 , G01L9/0055 , G01L9/045 , G01L9/065
摘要: Implantable pressure sensors and methods for making and using the same are provided. A feature of embodiments of the subject pressure sensors is that they are low-drift sensors. The subject sensors find use in a variety of applications.
摘要翻译: 提供了可植入压力传感器及其制造和使用方法。 目标压力传感器的实施例的特征在于它们是低漂移传感器。 主题传感器可用于各种应用。
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公开(公告)号:US06562404B1
公开(公告)日:2003-05-13
申请号:US09645826
申请日:2000-08-25
申请人: James A. Folta , Mark Zdeblick
发明人: James A. Folta , Mark Zdeblick
IPC分类号: C23C1634
CPC分类号: C23C16/045 , C23C16/345
摘要: A process for coating the inside surfaces of silicon microflow devices, such as electrophoresis microchannels, with a low-stress, conformal (uniform) silicon nitride film which has the ability to uniformly coat deeply-recessed cavities with, for example, aspect ratios of up to 40:1 or higher. The silicon nitride coating allows extended exposure to caustic solutions. The coating enables a microflow device fabricated in silicon to be resistant to all classes of chemicals: acids, bases, and solvents. The process involves low-pressure (vacuum) chemical vapor deposition. The ultra-low-stress silicon nitride deposition process allows 1-2 &mgr;m thick films without cracks, and so enables extended chemical protection of a silicon microflow device against caustics for up to 1 year. Tests have demonstrated the resistance of the films to caustic solutions at both ambient and elevated temperatures to 65° C.
摘要翻译: 用低应力,共形(均匀)氮化硅膜涂覆诸如电泳微通道的硅微流装置的内表面的方法,其具有均匀地涂覆深凹陷空腔的能力,例如具有例如上升的纵横比 至40:1或更高。 氮化硅涂层允许延长暴露于苛性碱溶液。 该涂层使得在硅中制造的微流量装置能够抵抗所有类别的化学品:酸,碱和溶剂。 该方法涉及低压(真空)化学气相沉积。 超低应力氮化硅沉积工艺允许1-2毫米厚的薄膜没有裂缝,因此可以延长硅微流量装置的化学保护,防止焦烧液长达1年。 测试已经证明了膜在环境温度和高温至65℃时对苛性碱溶液的耐受性。
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公开(公告)号:US6129331A
公开(公告)日:2000-10-10
申请号:US82423
申请日:1998-05-20
申请人: Albert Karl Henning , Mark Zdeblick , John Stuart Fitch , Dean Allyn Hopkins, Jr. , Leslie Joe Lilly
发明人: Albert Karl Henning , Mark Zdeblick , John Stuart Fitch , Dean Allyn Hopkins, Jr. , Leslie Joe Lilly
IPC分类号: B81B3/00 , B81C1/00 , F15C5/00 , F16K31/00 , F16K31/02 , F16K31/126 , F16K99/00 , F25B41/04 , F25B41/06
CPC分类号: F16K99/0001 , F15C5/00 , F16K31/002 , F16K31/126 , F16K99/0015 , F16K99/0044 , F16K99/0061 , F25B41/062 , F16K2099/0098 , F25B2341/0651 , F25B2400/15 , Y02B30/72 , Y10T137/6606
摘要: A thernopneumatic valve comprises a fluid channel plate defining a fluid port. A diaphragm plate is attached to the fluid channel plate. The diaphragm plate includes a displaceable diaphragm to selectively obstruct the fluid port of the fluid channel plate. A thermal isolating heater is connected to the diaphragm plate. The thermal isolating heater includes a thermal isolating heater body with a heating surface, a perimeter wall defining an extended axial cavity to confine a thermopneumatic working fluid that is used to control the position of the displaceable diaphragm, and a diaphragm obstruction structure to limit the motion of the displaceable diaphragm into the extended axial cavity.
摘要翻译: 气动阀包括限定流体端口的流体通道板。 隔膜板连接到流体通道板。 隔膜板包括可移动隔膜以选择性地阻塞流体通道板的流体端口。 隔热加热器连接到隔膜板。 热隔离加热器包括具有加热表面的隔热加热器主体,限定扩展轴向空腔的周边壁,以限制用于控制可移动隔膜位置的热气动工作流体,以及限制运动的隔膜阻塞结构 的可移动隔膜进入延伸的轴向腔。
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公开(公告)号:US5017266A
公开(公告)日:1991-05-21
申请号:US463056
申请日:1990-01-10
申请人: Mark Zdeblick , Thomas R. Albrecht
发明人: Mark Zdeblick , Thomas R. Albrecht
IPC分类号: G01B7/34 , B44C1/22 , G01N23/00 , G01N23/225 , G01N27/00 , G01N37/00 , G01Q10/06 , G01Q20/04 , G01Q30/04 , G01Q60/10 , G01Q60/16 , G01Q70/16 , G01Q80/00 , G11B9/00 , G11B9/04 , G11B9/14 , G11C13/00 , G11C13/04 , H01J37/20 , H01J37/28 , H01L41/09 , H01L41/22 , H02N2/00
CPC分类号: H01L41/0966 , B82Y35/00 , G01Q10/045 , G01Q60/16 , G11B9/14 , G11B9/1418 , G11B9/1436 , G11B9/1472 , H01J37/20 , H01L41/316 , B82Y10/00 , G01Q80/00 , Y10S977/837 , Y10S977/861 , Y10S977/872 , Y10S977/873 , Y10S977/943 , Y10S977/947 , Y10T29/42
摘要: There is disclosed herein an integrated scanning tunneling microscope and an integrated piezoelectric transducer and methods for making both. The device consists of one or two arm piezoelectric bimorph cantilevers formed by micromachining using standard integrated circuit processing steps. These cantilevers are attached to the substrate at one area and are free to move under the influence of piezoelectric forces which are caused by the application of appropriate voltages generated by control circuitry and applied to pairs of electrodes formed as an integral part of the bimorph cantilever structure. The electric fields caused by the control voltages cause the piezoelectric bimorphs to move in any desired fashion within ranges determined by the design. The bimorph cantilevers have tips with very sharp points formed thereon which are moved by the action of the control circuit and the piezoelectric bimorphs so to stay within a very small distance of a conducting surface. The movements of the tip can be tracked to yield an image of the surface at atomic resolution.
摘要翻译: 这里公开了一种集成的扫描隧道显微镜和集成的压电换能器以及用于制造两者的方法。 该器件由使用标准集成电路处理步骤的微加工形成的一个或两个臂压电双压电晶片悬臂组成。 这些悬臂在一个区域附接到基板,并且在由施加由控制电路产生的适当电压引起的压电力的影响下自由移动并施加到形成为双压电晶片悬臂结构的组成部分的电极对 。 由控制电压引起的电场导致压电双晶片以任何期望的方式在由设计确定的范围内移动。 双压电晶片悬臂具有形成在其上的非常锋利点的尖端,其通过控制电路和压电双压电晶片的作用移动以保持在导电表面的非常小的距离内。 可以跟踪尖端的运动以在原子分辨率下产生表面的图像。
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公开(公告)号:US4906840A
公开(公告)日:1990-03-06
申请号:US149236
申请日:1988-01-27
申请人: Mark Zdeblick , Thomas R. Albrecht
发明人: Mark Zdeblick , Thomas R. Albrecht
IPC分类号: G01B7/34 , B44C1/22 , G01N23/00 , G01N23/225 , G01N27/00 , G01N37/00 , G01Q10/06 , G01Q20/04 , G01Q30/04 , G01Q60/10 , G01Q60/16 , G01Q70/16 , G01Q80/00 , G11B9/00 , G11B9/04 , G11B9/14 , G11C13/00 , G11C13/04 , H01J37/20 , H01J37/28 , H01L41/09 , H01L41/22 , H02N2/00
CPC分类号: H01L41/0966 , B82Y35/00 , G01Q10/045 , G01Q60/16 , G11B9/14 , G11B9/1418 , G11B9/1436 , G11B9/1472 , H01J37/20 , H01L41/316 , B82Y10/00 , G01Q80/00 , Y10S977/837 , Y10S977/861 , Y10S977/872 , Y10S977/873 , Y10S977/943 , Y10S977/947 , Y10T29/42
摘要: There is disclosed herein an integrated scanning tunneling microscope and an integrated piezoelectric transducer and methods for making both. The device consists of one or two arm piezoelectric bimorph cantilevers formed by micromachining using standard integrated circuit processing steps. These cantilevers are attached to the substrate at one area and are free to move under the influence of piezoelectric forces which are caused by the application of appropriate voltages generated by control circuitry and applied to pairs of electrodes formed as an integral part of the bimorph cantilever structure. The electric fields caused by the control voltages cause the piezoelectric bimorphs to move in any desired fashion within ranges determined by the design. The bimorph cantilevers have tips with very sharp points formed thereon which are moved by the action of the control circuit and the piezoelectric bimorphs so to stay within a very small distance of a conducting surface. The movements of the tip can be tracked to yield an image of the surface at atomic resolution.
摘要翻译: 这里公开了一种集成的扫描隧道显微镜和集成的压电换能器以及用于制造两者的方法。 该器件由使用标准集成电路处理步骤的微加工形成的一个或两个臂压电双压电晶片悬臂组成。 这些悬臂在一个区域附接到基板,并且在由施加由控制电路产生的适当电压引起的压电力的影响下自由移动并施加到形成为双压电晶片悬臂结构的组成部分的电极对 。 由控制电压引起的电场导致压电双晶片以任何期望的方式在由设计确定的范围内移动。 双压电晶片悬臂具有形成在其上的非常锋利点的尖端,其通过控制电路和压电双压电晶片的作用移动以保持在导电表面的非常小的距离内。 可以跟踪尖端的运动以在原子分辨率下产生表面的图像。
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公开(公告)号:US09270025B2
公开(公告)日:2016-02-23
申请号:US12530431
申请日:2008-03-07
申请人: Timothy Robertson , Mark Zdeblick
发明人: Timothy Robertson , Mark Zdeblick
CPC分类号: H01Q7/00 , A61B5/0031 , A61B5/0205 , A61B5/073 , A61B5/1104 , A61B2562/08 , H01Q1/08 , H01Q21/20
摘要: Deployable antennas for in-body devices, such as implantable and ingestible devices, are provided. Aspects of the in-body deployable antennas of the invention include antennas configured to go from a first configuration to a second configuration following placement in a living body, e.g., via ingestion or implantation. Embodiments of the in-body devices are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.
摘要翻译: 提供用于体内器件的可部署天线,例如可植入和可摄取的设备。 本发明的体内可展开天线的方面包括配置成在放置在生物体中(例如通过摄取或植入)之后从第一配置转到第二配置的天线。 身体内装置的实施例被配置为在与目标生理部位接触时发出可检测信号。 还提供了制造和使用本发明的装置的方法。
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公开(公告)号:US09198608B2
公开(公告)日:2015-12-01
申请号:US13304274
申请日:2011-11-23
申请人: Hooman Hafezi , David O'Reilly , Patricia Johnson , Zahedeh Hatamkhany , Timothy Robertson , Mark Zdeblick
发明人: Hooman Hafezi , David O'Reilly , Patricia Johnson , Zahedeh Hatamkhany , Timothy Robertson , Mark Zdeblick
IPC分类号: G08B13/14 , A61B5/145 , A61B5/07 , A61J3/00 , H01Q1/27 , A61B5/01 , A61B5/03 , A61B5/1473 , A61B5/00 , H04B1/3888 , H04B1/38
CPC分类号: G08B21/18 , A61B5/01 , A61B5/036 , A61B5/073 , A61B5/14539 , A61B5/1473 , A61B5/4839 , A61B2562/0214 , A61J3/007 , B65D41/02 , H01Q1/273 , H04B1/3888 , H04B2001/3894
摘要: The system of the present invention includes a container and an electronic component with a partial power source in the form of dissimilar materials. The container includes a liquid. Upon contact with the liquid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature.
摘要翻译: 本发明的系统包括容器和具有不同材料形式的部分动力源的电子部件。 容器包括液体。 当与液体接触时,产生电压电位并且电源完成,这激活了系统。 电子部件控制不同材料之间的电导,以产生独特的当前签名。
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公开(公告)号:US08847766B2
公开(公告)日:2014-09-30
申请号:US11912475
申请日:2006-04-28
CPC分类号: A61B5/073 , A61B5/0028 , A61B5/0031 , A61B5/07 , A61B5/076 , A61B5/1473 , A61B5/4833 , A61B5/4839 , A61B5/681 , A61B5/6861 , A61B5/7282 , A61B2560/0214 , A61B2560/0462 , A61B2562/08 , A61B2562/162 , A61J3/007 , G06F19/00 , G06K7/10168 , H01Q1/273 , Y10T29/49117
摘要: Compositions, systems and methods that allow for the detection of the actual physical delivery of a pharmaceutical agent to a body are provided. Embodiments of the compositions include an identifier and an active agent. The invention finds use in a variety of different applications, including but not limited to, monitoring of therapeutic regimen compliance, tracking the history of pharmaceutical agents, etc.
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公开(公告)号:US20140203950A1
公开(公告)日:2014-07-24
申请号:US14234069
申请日:2012-07-17
IPC分类号: G08C17/02
CPC分类号: G08C17/02 , A61B5/073 , A61B5/4833 , A61B5/6803 , A61B5/6898 , G06F19/321 , G06F19/3418 , G06F19/3456 , G16H20/10 , G16H30/20 , G16H40/67
摘要: A mobile device for detecting an electrical signal generated by an ingestible event marker is disclosed. The mobile device includes a detection subsystem to receive an electrical signal generated by an ingestible event marker from a detection arrangement. A processing subsystem is coupled to the detection subsystem to decode the electrical signal. A radio subsystem is configured to transmit the decoded electrical signal to a wireless node. A system includes the mobile device and the detection arrangement. A method includes receiving the electrical signal generated by the ingestible event marker at the mobile device, decoding the electrical signal to extract information associated with the ingestible event marker, and transmitting the information to a wireless node.
摘要翻译: 公开了一种用于检测由可摄入事件标记产生的电信号的移动设备。 移动设备包括检测子系统,用于从检测装置接收由可摄取事件标记产生的电信号。 处理子系统耦合到检测子系统以解码电信号。 无线电子系统被配置为将解码的电信号发送到无线节点。 一种系统包括移动设备和检测装置。 一种方法包括:在移动设备处接收由可摄取事件标记产生的电信号,解码电信号以提取与可摄取事件标记相关联的信息,以及将信息发送到无线节点。
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100.
公开(公告)号:US08712549B2
公开(公告)日:2014-04-29
申请号:US10734490
申请日:2003-12-11
申请人: Mark Zdeblick , George M. Savage
发明人: Mark Zdeblick , George M. Savage
IPC分类号: A61N1/00
CPC分类号: A61B5/036 , A61B5/0422 , A61B18/1492 , A61B18/22 , A61B2562/02 , A61N1/0529 , A61N1/0551 , A61N1/0553 , A61N1/056
摘要: A multiplexed medical carrier provides for sensing one or more patient parameters and/or delivering energy via separately identifiable effectors. The carrier includes a body and at least two electrical conductors coupled with at least two effectors. Effectors may be any combination of sensors, actuators or both. Sensors may measure such parameters as pressure, oxygen content, volume, conductivity, fluid flow rate, or any other chemical or physical parameters. Actuators may be used, for example, to pace a heart, stimulate muscle or neural tissue, broadcast ultrasonic energy, emit light, heat or other forms of radiation, or deliver any form of energy or substance. A method for collecting medical data from a patient includes interrogating a network of multiplexed sensors residing on parallel conductors in the patient, including addressing a first addressable sensor in the network to obtain data and addressing a second addressable sensor in the network to obtain data.
摘要翻译: 复用的医疗载体提供用于感测一个或多个患者参数和/或通过单独识别的效应器递送能量。 载体包括主体和与至少两个效应器耦合的至少两个电导体。 效应器可以是传感器,致动器或两者的任何组合。 传感器可以测量诸如压力,氧含量,体积,电导率,流体流速或任何其它化学或物理参数的参数。 例如,可以使用致动器来调节心脏,刺激肌肉或神经组织,广播超声能量,发射光,热或其他形式的辐射,或递送任何形式的能量或物质。 一种用于从患者收集医学数据的方法包括询问驻留在患者的并行导体上的复用传感器的网络,包括寻址网络中的第一可寻址传感器以获得数据并寻址网络中的第二可寻址传感器以获得数据。
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