公开(公告)号：US20130267738A1

公开(公告)日：2013-10-10

申请号：US13702388

申请日：2011-06-08

Applicant: Peng Zhang ,  Yu Huang ,  Zhedong Yuan ,  Hanbin Shan ,  Xiong Yu

Inventor： Peng Zhang ,  Yu Huang ,  Zhedong Yuan ,  Hanbin Shan ,  Xiong Yu

IPC: C07C231/06 ,  C07C233/22

CPC classification number: C07C231/06 ,  C07C231/12 ,  C07C233/18 ,  C07C233/22 ,  C07C2602/10

Abstract: The present invention relates to the intermediate compounds for preparation of agomelatine, as well as the preparation methods thereof. The intermediate of the present invention for preparation of agomelatine is compound A as shown in the following formula. Also provided are two novel intermediate compounds. When we use these new intermediate compounds to prepare agomelatine, it is simple to manipulate, well-controlled and with high purity, without complicated operations such as rectification and column chromatography separation, and suitable for industrial production. Meanwhile, the preparation methods of the two new intermediates themselves is simple and high yield, only using the most commonly-used 7-methoxy-tetralone as original starting material and undergoing one step of reaction to obtain the intermediates, followed by one more step of converting the intermediate compounds to desired product agomelatine. Said reaction processes are greatly simplified, with the reaction yield being improved and the difficulty in purification of previous method being overcome, as compare with the previous technique for preparation of agomelatine. Typically, the yield of the present invention is over 70%.

Abstract translation: 本发明涉及用于制备agomelatine的中间体化合物及其制备方法。 本发明的用于制备agomelatine的中间体是下式所示的化合物A. 还提供两种新型中间体化合物。 当我们使用这些新的中间体化合物来制备agomelatine时，其操作简单，控制良好，纯度高，无需精馏和柱层析分离等复杂操作，适用于工业生产。 同时，两种新中间体本身的制备方法简单高产，仅使用最常用的7-甲氧基 - 四氢萘酮作为起始原料，经过一步反应得到中间体，再加入一步 将中间体化合物转化成所需的产物agomelatine。 所述反应过程被大大简化，与先前用于制备agMelatine的技术相比，反应产率提高并克服了先前方法的纯化困难。 通常，本发明的产率超过70％。

公开(公告)号：US08438438B2

公开(公告)日：2013-05-07

申请号：US12948460

申请日：2010-11-17

Applicant: Yu Huang ,  Wu-Tung Cheng ,  Nagesh Tamarapalli ,  Randy Klingenberg ,  Janusz Rajski

Inventor： Yu Huang ,  Wu-Tung Cheng ,  Nagesh Tamarapalli ,  Randy Klingenberg ,  Janusz Rajski

IPC: G01R31/28

CPC classification number: G01R31/3177 ,  G01R31/318569

Abstract: Chain or logic diagnosis resolution can be enhanced in the presence of limited failure cycles using embodiments of the various methods, systems, and apparatus described herein. For example, pattern sets can be ordered according to a diagnosis coverage figure, which can be used to measure chain or logic diagnosability of the pattern set. Per-pin based diagnosis techniques can also be used to analyze limited failure data.

公开(公告)号：US08394776B2

公开(公告)日：2013-03-12

申请号：US12523314

申请日：2008-01-16

Applicant: Bing Guang ,  Junjian Liu ,  Guangxin Dong ,  Xiangyang Peng ,  Xiaoxia Gong ,  Zhen Huang ,  Meirong Zhou ,  Wei Zhan ,  Jufang Yan ,  Yu Huang ,  Dongguang Qin ,  Jianxin Ji ,  Bogang Li

Inventor： Bing Guang ,  Junjian Liu ,  Guangxin Dong ,  Xiangyang Peng ,  Xiaoxia Gong ,  Zhen Huang ,  Meirong Zhou ,  Wei Zhan ,  Jufang Yan ,  Yu Huang ,  Dongguang Qin ,  Jianxin Ji ,  Bogang Li

IPC: A01N43/04 ,  A61K31/70

CPC classification number: A61K31/704

Abstract: The invention provides the use of ursolic acid saponin and oleanolic acid saponin of formula (I) in preparing medicaments for increasing leucocytes and/or platelets. The invention also provides a pharmaceutical composition containing the same compound. The invention utilizes the cheap and accessible ursolic acid and oleanolic acid which are widely present in natural plants as raw materials, introduces monosaccharyls or oligosaccharyls by structural modification. It is proved by pharmacological tests that the compound of formula (I) have an activity of obviously increasing leucocytes and/or platelets.

Abstract translation: 本发明提供式（I）的熊果酸皂苷和齐墩果酸皂苷在制备用于增加白细胞和/或血小板的药物中的用途。 本发明还提供含有相同化合物的药物组合物。 本发明利用广泛存在于天然植物中的廉价可及的熊果酸和齐墩果酸作为原料，通过结构改性引入单糖基或寡糖基。 通过药理学实验证明，式（I）化合物具有明显增加白细胞和/或血小板的活性。

公开(公告)号：US20130008380A1

公开(公告)日：2013-01-10

申请号：US13610798

申请日：2012-09-11

Applicant: Chia-Chih CHUANG ,  Yu Huang

Inventor： Chia-Chih CHUANG ,  Yu Huang

IPC: H01L21/203

CPC classification number: H01L21/02568 ,  C23C14/0623 ,  C23C14/228 ,  C23C14/24 ,  H01L21/02614

Abstract: An apparatus for fabricating IB-IIIA-VIA2 compound semiconductor thin films is provided, including a reaction chamber, a pressure control unit connected with the reaction chamber, a pedestal disposed in the reaction chamber wherein the at least one substrate includes elements of group IB and group IIIA, a first group VIA element supply unit connecting with the reaction chamber for providing vaporized first group VIA elements into the reaction chamber, and a plasma unit disposed in the reaction chamber. In one embodiment, during a reaction in the reaction chamber, the vaporized first group VIA elements flow through the high density plasma region and transform into ionized first group VIA elements, and the ionized first group VIA elements diffuse into the at least one substrate comprising elements of group IB and group IIIA to form a IB-IIIA-VIA2 compound semiconductor thin film thereover.

Abstract translation: 提供一种用于制造IB-IIIA-VIA2化合物半导体薄膜的装置，包括反应室，与反应室连接的压力控制单元，设置在反应室中的基座，其中至少一个基板包括组1B和 组IIIA，与反应室连接的用于将蒸发的第一组VIA元件提供到反应室中的第一组VIA元件供应单元和设置在反应室中的等离子体单元。 在一个实施方案中，在反应室中的反应期间，蒸发的第一组VIA元素流过高密度等离子体区域并转化成电离的第一组VIA元素，并且离子化的第一组VIA元素扩散到至少一个包含元素 的IB和IIIA族以形成IB-IIIA-VIA2化合物半导体薄膜。

公开(公告)号：US08301414B2

公开(公告)日：2012-10-30

申请号：US11772648

申请日：2007-07-02

Applicant: Wu-Tung Cheng ,  Kun-Han Tsai ,  Yu Huang ,  Nagesh Tamarapalli ,  Janusz Rajski

Inventor： Wu-Tung Cheng ,  Kun-Han Tsai ,  Yu Huang ,  Nagesh Tamarapalli ,  Janusz Rajski

IPC: G06F11/30 ,  G01R31/28

CPC classification number: G01R31/318547 ,  G06F11/267

Abstract: Methods, apparatus, and systems for performing fault diagnosis are disclosed herein. In certain disclosed embodiments, methods for diagnosing faults from compressed test responses are provided. For example, in one exemplary embodiment, a circuit description of an at least partially scan-based circuit-under-test and a compactor for compacting test responses captured in the circuit-under-test is received. A transformation function performed by the compactor to the test responses captured in the circuit-under-test is determined. A diagnostic procedure for evaluating uncompressed test responses is modified into a modified diagnostic procedure that incorporates the transformation function therein. Computer-readable media comprising computer-executable instructions for causing a computer to perform any of the disclosed methods are also provided. Likewise, computer-readable media comprising lists of fault candidates identified by any of the disclosed methods or circuit descriptions created or modified by the disclosed methods are provided.

Abstract translation: 本文公开了用于执行故障诊断的方法，装置和系统。 在某些公开的实施例中，提供了用于从压缩测试响应诊断故障的方法。 例如，在一个示例性实施例中，接收至少部分基于扫描的测试电路和压实器的电路描述，用于压缩在待测电路中捕获的测试响应。 确定由压实机对被测电路中捕获的测试响应执行的变换功能。 用于评估未压缩测试响应的诊断程序被修改为并入其中的变换功能的修改的诊断过程。 还提供了包括用于使计算机执行任何所公开的方法的计算机可执行指令的计算机可读介质。 同样地，提供了包括通过由所公开的方法创建或修改的任何公开的方法或电路描述所识别的故障候选列表的计算机可读介质。

公开(公告)号：US20120137727A1

公开(公告)日：2012-06-07

申请号：US13370062

申请日：2012-02-09

Applicant: Yu Huang ,  Richard W. Baker ,  Benjamin McCool ,  Rong Dong

Inventor： Yu Huang ,  Richard W. Baker ,  Benjamin McCool ,  Rong Dong

IPC: F25J3/08

CPC classification number: B01D53/228 ,  B01D3/145 ,  B01D61/362 ,  B01D71/32 ,  B01D71/44 ,  B01D2311/2669 ,  C07C29/76 ,  C07C31/08

Abstract: Disclosed herein are processes for removing water from organic solvents, such as ethanol. The processes include distillation in two columns operated at sequentially higher pressure, followed by treatment of the overhead vapor by one or two membrane separation steps.

Abstract translation: 本文公开了从有机溶剂如乙醇中除去水的方法。 这些方法包括在连续较高压力下运行的两个塔中进行蒸馏，然后通过一个或两个膜分离步骤处理塔顶蒸气。

公开(公告)号：US20120123780A1

公开(公告)日：2012-05-17

申请号：US13297142

申请日：2011-11-15

Applicant: Jizhou Gao ,  Yu Huang ,  Hong Heather Yu

Inventor： Jizhou Gao ,  Yu Huang ,  Hong Heather Yu

IPC: G06K9/62 ,  G10L15/06

CPC classification number: G10L15/02 ,  G06K9/00744 ,  G06K9/00751 ,  G06K9/00765 ,  G10L15/08 ,  H04N21/4358 ,  H04N21/44008 ,  H04N21/44016 ,  H04N21/44029 ,  H04N21/8549

Abstract: A video summary method comprises dividing a video into a plurality of video shots, analyzing each frame in a video shot from the plurality of video shots, determining a saliency of each frame of the video shot, determining a key frame of the video shot based on the saliency of each frame of the video shot, extracting visual features from the key frame and performing shot clustering of the plurality of video shots to determine concept patterns based on the visual features. The method further comprises fusing different concept patterns using a saliency tuning method and generating a summary of the video based upon a global optimization method.

Abstract translation: 视频摘要方法包括将视频分成多个视频镜头，分析来自多个视频镜头的视频镜头中的每个帧，确定视频镜头的每个帧的显着性，基于 视频拍摄的每帧的显着性，从关键帧提取视觉特征并执行多个视频镜头的拍摄聚类，以基于视觉特征来确定概念模式。 该方法还包括使用显着性调整方法来融合不同的概念模式，并且基于全局优化方法生成视频的摘要。

公开(公告)号：US20120102154A1

公开(公告)日：2012-04-26

申请号：US13277067

申请日：2011-10-19

Applicant: Yu Huang ,  Xutao Lv ,  Yue Chen ,  Hong Heather Yu

Inventor： Yu Huang ,  Xutao Lv ,  Yue Chen ,  Hong Heather Yu

IPC: G06F15/16

CPC classification number: H04L67/06 ,  H04L65/4084 ,  H04L65/605

Abstract: Methods and systems for transcoding in a cloud computing platform are disclosed. According to an embodiment, a receiver receives an uploading file by one data block at a time, and stores the received data blocks in various storage modules. Small segment files are then generated when the size of the received data blocks is larger than a threshold. A transcoder transcodes the small segment files from one format such as a bit rate or a frame size to another while the receiver is still receiving a new data block. The transcoded small segment files may be stitched together to form a stitched file, which may be stored in a storage module to be downloaded through a content distribution network (CDN). The transcoded small segment files may be passed to streaming servers for streaming over a network while the receiver is still receiving a new data block of the uploading file.

Abstract translation: 公开了用于云计算平台中的代码转换的方法和系统。 根据实施例，接收机一次由一个数据块接收上传文件，并将接收到的数据块存储在各种存储模块中。 然后当接收的数据块的大小大于阈值时，生成小段文件。 当接收器仍然接收到新的数据块时，代码转换器将小段文件从诸如比特率或帧大小的格式转码为另一种格式。 代码转换的小段文件可以被缝合在一起以形成缝合文件，其可以存储在存储模块中以通过内容分发网络（CDN）下载。 代码转换的小段文件可以被传递到流服务器，用于通过网络进行流传输，同时接收器仍然接收上传文件的新数据块。

公开(公告)号：US08153470B2

公开(公告)日：2012-04-10

申请号：US11543337

申请日：2006-10-04

Applicant: Charles M. Lieber ,  Yi Cui ,  Xiangfeng Duan ,  Yu Huang

Inventor： Charles M. Lieber ,  Yi Cui ,  Xiangfeng Duan ,  Yu Huang

IPC: H01L51/40

CPC classification number: H01L29/0665 ,  B01J23/50 ,  B01J23/52 ,  B01J23/72 ,  B01J35/0013 ,  B01J37/349 ,  B81C1/0019 ,  B81C1/00206 ,  B82Y10/00 ,  B82Y15/00 ,  B82Y30/00 ,  B82Y40/00 ,  C30B11/00 ,  C30B25/005 ,  C30B29/605 ,  G01N27/4146 ,  G01N33/54373 ,  G11C13/0014 ,  G11C13/0019 ,  G11C13/025 ,  G11C13/04 ,  G11C2213/77 ,  G11C2213/81 ,  H01L21/02521 ,  H01L21/02532 ,  H01L21/0254 ,  H01L21/02543 ,  H01L21/02557 ,  H01L21/0256 ,  H01L21/02573 ,  H01L21/02581 ,  H01L21/02603 ,  H01L21/02606 ,  H01L21/0262 ,  H01L21/02628 ,  H01L21/02631 ,  H01L21/02636 ,  H01L21/02639 ,  H01L21/02645 ,  H01L21/02653 ,  H01L23/53276 ,  H01L29/045 ,  H01L29/0673 ,  H01L29/068 ,  H01L29/16 ,  H01L29/1602 ,  H01L29/18 ,  H01L29/20 ,  H01L29/207 ,  H01L29/22 ,  H01L29/24 ,  H01L29/26 ,  H01L29/267 ,  H01L33/06 ,  H01L33/18 ,  H01L33/20 ,  H01L51/002 ,  H01L51/0048 ,  H01L2924/0002 ,  Y02E10/549 ,  Y02P70/521 ,  Y10S438/962 ,  Y10S977/762 ,  Y10S977/847 ,  Y10S977/858 ,  Y10S977/882 ,  Y10S977/883 ,  Y10S977/892 ,  Y10S977/936 ,  Y10T428/24 ,  H01L2924/00

Abstract: A method for selectively aligning and positioning semiconductor nanowires on a substrate by providing a substrate; patterning electrodes on a surface of the substrate; conditioning the surface of the substrate to attach semiconductor nanowires to the surface by functionalizing the surface with a first functional group having an affinity for the semiconductor nanowires; providing an environment in contact with the electrodes, the environment having suspended therein the semiconductor nanowires; and providing an electric field between the electrodes, thereby causing the nanowires in the environment to align between and electrically connect the electrodes to thereby form a semiconducting channel between the electrodes.

Abstract translation: 一种用于通过提供衬底在衬底上选择性地对准和定位半导体纳米线的方法; 在基板的表面上构图电极; 通过用对半导体纳米线具有亲和性的第一官能团官能化表面来调节衬底的表面以将半导体纳米线附着到表面上; 提供与电极接触的环境，其中悬浮有半导体纳米线的环境; 并且在电极之间提供电场，从而使环境中的纳米线在电极之间对齐并电连接，从而在电极之间形成半导体通道。

公开(公告)号：US08123943B2

公开(公告)日：2012-02-28

申请号：US12794445

申请日：2010-06-04

Applicant: Nicholas P Wynn ,  Yu Huang ,  Tiem Aldajani ,  Donald A Fulton

Inventor： Nicholas P Wynn ,  Yu Huang ,  Tiem Aldajani ,  Donald A Fulton

IPC: B01D15/00 ,  C02F1/44

CPC classification number: B01D61/362 ,  B01D1/22 ,  B01D1/26 ,  B01D3/001 ,  B01D3/145 ,  B01D63/12 ,  B01D2311/08 ,  B01D2311/12 ,  B01D2313/38 ,  B01D2319/022

Abstract: The invention is a pervaporation process and pervaporation equipment, using a series of membrane modules, and including inter-module reheating of the feed solution under treatment. The inter-module heating is achieved within the tube or vessel in which the modules are housed, thereby avoiding the need to repeatedly extract the feed solution from the membrane module train.

Abstract translation: 本发明是一种渗透蒸发过程和渗透蒸发设备，使用一系列膜模块，并且包括处理进料溶液的模块间再加热。 模块内加热是在容纳模块的管或容器中实现的，从而避免了从膜模块列反复提取进料溶液的需要。