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1263 条记录 (耗时 0.033 秒)

    Cationic antiseptic compositions and methods of use
    127.
    发明授权
    Cationic antiseptic compositions and methods of use 有权
    阳离子防腐剂组合物及使用方法

    公开(公告)号：US09028852B2

    公开(公告)日：2015-05-12

    申请号：US10936135

    申请日：2004-09-07

    申请人： Matthew T. Scholz

    发明人： Matthew T. Scholz

    IPC分类号： A61K31/14 ,  A61K33/38 ,  A61K8/72 ,  A61K8/00 ,  A61K45/06

    CPC分类号： A61K47/10 ,  A01N25/04 ,  A01N47/44 ,  A61J1/00 ,  A61K9/0014 ,  A61K9/06 ,  A61K31/085 ,  A61K31/14 ,  A61K31/155 ,  A61K31/185 ,  A61K31/191 ,  A61K31/194 ,  A61K31/685 ,  A61K31/785 ,  A61K33/38 ,  A61K45/06 ,  A61K47/183 ,  A61K47/186 ,  A61K47/34 ,  B65D21/086 ,  Y02A50/473

    摘要： Antimicrobial compositions, especially those useful when applied topically, particularly to mucosal tissues (i.e., mucous membranes), including a cationic antiseptic such as biguanides and bisbiguanides such as chlorhexidine and its various salts including but not limited to the digluconate, diacetate, dimethosulfate, and dilactate salts; polymeric quaternary ammonium compounds such as polyhexamethylenebiguanide; silver and various silver complexes; small molecule quaternary ammonium compounds such as benzalkoium chloride and alkyl substituted derivatives; di-long chain alkyl (C8-C18) quaternary ammonium compounds; cetylpyridinium halides and their derivatives; benzethonium chloride and its alkyl substituted derivatives; and octenidine. The compositions can also include an enhancer component, a surfactant, a hydrophobic component, and/or a hydrophilic component. Such compositions provide effective topical antimicrobial activity and are accordingly useful in the treatment and/or prevention of conditions that are caused, or aggravated by, microorganisms (including viruses).

    摘要翻译： 抗微生物组合物，特别是当局部施用时特别是粘膜组织（即粘膜）上有用的组合物，包括阳离子防腐剂例如双胍类和双胍类如氯己定及其各种盐，包括但不限于二葡萄糖酸盐，二乙酸盐，二硫代硫酸盐和 稀释盐 聚合季铵化合物如聚六亚甲基双胍; 银和各种银配合物; 小分子季铵化合物如氯化苯甲酰氯和烷基取代衍生物; 二长链烷基（C8-C18）季铵化合物; 十六烷基吡啶鎓卤化物及其衍生物; 苄索氯铵及其烷基取代衍生物; 和辛烯尼碱。 组合物还可以包括增强剂组分，表面活性剂，疏水组分和/或亲水组分。 这样的组合物提供有效的局部抗微生物活性，因此可用于治疗和/或预防由微生物（包括病毒）引起或加剧的病症。

    ANTI-MICROBIAL DRESSING, AN ANTI-MICROBIAL COMPOSITION AND USE THEREOF
    128.
    发明申请
    ANTI-MICROBIAL DRESSING, AN ANTI-MICROBIAL COMPOSITION AND USE THEREOF 审中-公开
    抗微生物粘合剂，抗微生物组合物及其用途

    公开(公告)号：US20150057617A1

    公开(公告)日：2015-02-26

    申请号：US14389981

    申请日：2013-04-04

    申请人： EMODIAL S.r.l.

    发明人： Gianni Pecorari

    IPC分类号： A61L15/44 ,  A61M25/02 ,  A61L15/18 ,  A61K33/38 ,  A61L15/20 ,  A61F13/00 ,  A61K31/155

    CPC分类号： A61L15/44 ,  A61F13/00063 ,  A61F13/00068 ,  A61K31/155 ,  A61K33/38 ,  A61L15/18 ,  A61L15/20 ,  A61L15/42 ,  A61L15/46 ,  A61L26/0061 ,  A61L26/0066 ,  A61L26/0076 ,  A61L2300/104 ,  A61L2300/206 ,  A61L2300/404 ,  A61L2300/45 ,  A61L2300/624 ,  A61L2400/12 ,  A61M25/02 ,  A61M2025/0213 ,  A61M2025/0273

    摘要： The invention relates to an antimicrobial dressing, an anti-microbial composition and use thereof. The dressing comprises: chlorhexidine and/or a pharmaceutically acceptable salt thereof in a solid state in a quantity, calculated as an equivalent weight of chlorhexidine digluconate/surface of dressing, comprised between 0.013 and 2 g/m2; and silver and/or a pharmaceutically-acceptable salt in the solid state in a quantity, calculated as an equivalent weight of metallic silver/surface of dressing of greater than or equal to 0.1 g/m2. The composition comprises: chlorhexidine and/or a pharmaceutically acceptable salt thereof in a solid state in a relative weight/weight percentage, calculated as an equivalent weight of chlorhexidine digluconate/total weight of the composition, comprised between 0.01% and 0.09%; and silver and/or a pharmaceutically acceptable salt thereof in the solid state in a relative percentage weight/weight comprised between 0.00008% and 0.08%, calculated as an equivalent weight of metallic silver/total weight of the composition; and at least a pharmaceutically-acceptable excipient.

    摘要翻译： 本发明涉及抗微生物敷料，抗微生物组合物及其用途。 该敷料包括：固体状态的洗必太和/或其药学上可接受的盐，其量为以氯己定二葡萄糖酸盐/洗涤剂表面的当量计算，含量在0.013至2g / m 2之间; 和银和/或固体状态的药学上可接受的盐，其量以金属银/敷料表面的当量计算为大于或等于0.1g / m 2。 组合物包含：固体状态的氯己定和/或其药学上可接受的盐，其相对重量/重量百分比以组合物的洗必泰/当量重量计，为0.01％至0.09％; 和银和/或其药学上可接受的盐，其相对重量/重量在0.00008％和0.08％之间，以金属银的当量计算/组合物的总重量计算为固体状态; 和至少一种药学上可接受的赋形剂。

    ANTIMICROBIAL SANITIZER SYSTEMS AND METHODS OF KILLING OR INHIBITING PATHOGENS
    130.
    发明申请
    ANTIMICROBIAL SANITIZER SYSTEMS AND METHODS OF KILLING OR INHIBITING PATHOGENS 审中-公开
    抗生素杀虫剂系统和杀死或抑制病原体的方法

    公开(公告)号：US20140377318A1

    公开(公告)日：2014-12-25

    申请号：US14482254

    申请日：2014-09-10

    申请人： S. Douglas Cornell

    发明人： S. Douglas Cornell

    IPC分类号： A61L31/08 ,  A61L31/16 ,  A61K33/38 ,  A61K33/34 ,  A61K33/24 ,  A61K33/30

    CPC分类号： A61L31/088 ,  A61K33/24 ,  A61K33/30 ,  A61K33/34 ,  A61K33/38 ,  A61L31/16 ,  A61L2420/04 ,  A61M31/00 ,  A61M35/00 ,  A61M2210/04 ,  A61M2210/0618 ,  A61M2210/1067 ,  A61M2210/1475

    摘要： Methods and systems for killing or inhibiting pathogens present in treatments area including but not limited to the nasal cavity, the vaginal area, and the anal area. The methods feature introducing a substrate with an antimicrobial metal into the treatment area. The substrate may be coated, lined, plated, or clad with the antimicrobial metal, either partially or entirely. Or, the substrate itself may be an antimicrobial metal. Antimicrobial metals include but are not limited to copper, zinc, silver, gold, and certain metal alloys. The step of directly contacting the substrate with antimicrobial metal to the treatment area kills or inhibits present pathogens. The antimicrobial metal may leave a trace amount of residue, which may continue to kill or inhibit pathogens after the system has been removed from the treatment area or penetrate into deeper layers of the treatment area.

    摘要翻译： 用于杀死或抑制存在于治疗区域中的病原体的方法和系统包括但不限于鼻腔，阴道区域和肛门区域。 该方法特征是将具有抗微生物金属的底物引入治疗区域。 基底可以部分或全部地用抗微生物金属涂覆，衬里，电镀或包覆。 或者，衬底本身可以是抗微生物金属。 抗微生物金属包括但不限于铜，锌，银，金和某些金属合金。 将底物与抗微生物金属直接接触的处理区域的步骤杀死或抑制本病原体。 抗微生物金属可能留下微量的残留物，这可能在系统从处理区域中移出或渗入处理区域的较深层之后继续杀死或抑制病原体。