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    Scan pattern and signal processing for optical coherence tomography
    151.
    发明授权
    Scan pattern and signal processing for optical coherence tomography 有权

    公开(公告)号：US11369266B2

    公开(公告)日：2022-06-28

    申请号：US17248870

    申请日：2021-02-11

    Applicant: ACUCELA INC.

    Inventor： Ryo Kubota ,  Stephan Wyder ,  Philip M. Buscemi ,  Matthias Pfister ,  Alexander Holzer

    IPC: A61B3/10 ,  G01B9/02 ,  A61B3/12 ,  G01B9/02004 ,  G01B9/02091

    Abstract: An OCT system for measuring a retina as part of an eye health monitoring and diagnosis system. The OCT system includes an OCT interferometer, where the interferometer comprises a light source or measurement beam and a scanner for moving the beam on the retina of a patient's eye, and a processor configured to execute instructions to cause the scanner to move the measurement beam on the retina in a scan pattern. The scan pattern is a continuous pattern that includes a plurality of lobes. The measurement beam may be caused to move on the retina by the motion of a mirror that intercepts and redirects the measurement beam. The mirror position may be altered by the application of a drive signal to one or more actuators that respond to the drive signal by rotating the mirror about an axis or axes.

    Electro-switchable spectacles for myopia treatment
    152.
    发明授权
    Electro-switchable spectacles for myopia treatment 有权

    公开(公告)号：US11320674B2

    公开(公告)日：2022-05-03

    申请号：US17302827

    申请日：2021-05-13

    Applicant: ACUCELA INC.

    Inventor： Ryo Kubota ,  Amitava Gupta

    IPC: G02C7/08 ,  G02F1/29

    Abstract: An apparatus to treat refractive error of an eye comprises an electroactive component configured to switch between a light scattering or optical power providing configuration to treat refractive error of the eye and a substantially transparent configuration to allow normal viewing. The electroactive component can be located on the lens away from a central axis of the lens to provide light to a peripheral region of the retina to decrease the progression of myopia. The electroactive component can be located on the lens away from the central axis of the lens in order for the wearer to view objects through an optical zone while the electroactive component scatters light. The electroactive component can be configured to switch to the substantially transparent configuration to allow light to pass through the electroactive component and to allow the lens to refract light to correct vision and allow normal viewing through the lens.

    Apparatus and methods for the treatment of refractive error using active stimulation
    153.
    发明授权
    Apparatus and methods for the treatment of refractive error using active stimulation 有权

    公开(公告)号：US11281022B2

    公开(公告)日：2022-03-22

    申请号：US17303889

    申请日：2021-06-09

    Applicant: ACUCELA INC.

    Inventor： Philip M. Buscemi ,  Ryo Kubota

    IPC: G02B27/01 ,  G02C7/04 ,  G02C7/14

    Abstract: Systems, devices, apparatuses and methods for an active projection system that may be incorporated into spectacles, contact lenses or provided as an add-on layer to existing spectacles or lenses. The active projection system operates to generate a stimulus or stimuli for viewing by a person's eye. The stimulus or stimuli creates an image that is defocused in front of the person's retina and can assist in slowing or stopping the progression of myopia or other refractive errors in the person.

    ARTIFICIAL INTELLIGENCE FOR EVALUATION OF OPTICAL COHERENCE TOMOGRAPHY IMAGES
    154.
    发明申请
    ARTIFICIAL INTELLIGENCE FOR EVALUATION OF OPTICAL COHERENCE TOMOGRAPHY IMAGES 有权

    公开(公告)号：US20220084197A1

    公开(公告)日：2022-03-17

    申请号：US17444806

    申请日：2021-08-10

    Applicant: ACUCELA INC.

    Inventor： Stephan WYDER ,  Matthias PFISTER ,  Cyril STOLLER ,  Philip M. BUSCEMI

    IPC: G06T7/00 ,  G06T7/11 ,  G06T3/00 ,  G06N3/08 ,  G16H30/40

    Abstract: A neural network is trained to segment interferogram images. A first plurality of interferograms are obtained, where each interferograms corresponds to data acquired by an OCT system using a first scan pattern, annotating each of the plurality of interferograms to indicate a tissue structure of a retina, training a neural network using the plurality of interferograms and the annotations, inputting a second plurality of interferograms corresponding to data acquired by an OCT system using a second scan pattern and obtaining an output of the trained neural network indicating the tissue structure of the retina that was scanned using the second scan pattern. The system and methods may instead receive a plurality of A-scans and output a segmented image corresponding to a plurality of locations along an OCT scan pattern.

    ELECTRO-SWITCHABLE SPECTACLES FOR MYOPIA TREATMENT
    155.
    发明申请
    ELECTRO-SWITCHABLE SPECTACLES FOR MYOPIA TREATMENT 有权

    公开(公告)号：US20210356767A1

    公开(公告)日：2021-11-18

    申请号：US17302827

    申请日：2021-05-13

    Applicant: ACUCELA INC.

    Inventor： Ryo KUBOTA ,  Amitava GUPTA

    IPC: G02C7/08 ,  G02F1/29

    Abstract: An apparatus to treat refractive error of an eye comprises an electroactive component configured to switch between a light scattering or optical power providing configuration to treat refractive error of the eye and a substantially transparent configuration to allow normal viewing. The electroactive component can be located on the lens away from a central axis of the lens to provide light to a peripheral region of the retina to decrease the progression of myopia. The electroactive component can be located on the lens away from the central axis of the lens in order for the wearer to view objects through an optical zone while the electroactive component scatters light. The electroactive component can be configured to switch to the substantially transparent configuration to allow light to pass through the electroactive component and to allow the lens to refract light to correct vision and allow normal viewing through the lens.

    DEVICE FOR PROJECTING IMAGES ON THE RETINA
    156.
    发明申请
    DEVICE FOR PROJECTING IMAGES ON THE RETINA 有权

    公开(公告)号：US20210031051A1

    公开(公告)日：2021-02-04

    申请号：US16947537

    申请日：2020-08-05

    Applicant: ACUCELA INC.

    Inventor： Ryo KUBOTA ,  Karim HAROUD ,  Beat WYSS ,  Hans BERNARD ,  Jean-Noël FEHR ,  Patrizia WEBER ,  Moritz HAEBERLI ,  Amitava GUPTA

    IPC: A61N5/06 ,  G02B27/30 ,  G02B27/01

    Abstract: A device to stimulate the retina comprises one or more light sources coupled to one or more optical elements. The one or more optical elements is configured to illuminate the retina with one or more images at a location away from a fovea of a wearer. In some embodiments, each of the one or more images comprises a depth of focus and a spatial resolution. The one or more images can be formed at a distance anterior to the retina, at a distance posterior to the retina or on the retina. In some embodiments, the depth of focus is less than the distance, and the spatial resolution greater than a spatial resolution of the retina at the location.

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