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    Device for the ablation of tissue
    181.
    发明授权
    Device for the ablation of tissue 失效
    用于消融组织的装置

    公开(公告)号：US06911027B1

    公开(公告)日：2005-06-28

    申请号：US09302055

    申请日：1999-04-29

    Applicant: Stuart D. Edwards ,  James A. Filice ,  Benjamin T. Nordell ,  Brian O. Armijo

    Inventor： Stuart D. Edwards ,  James A. Filice ,  Benjamin T. Nordell ,  Brian O. Armijo

    IPC: A61B17/24 ,  A61B18/12 ,  A61B18/14 ,  A61B18/18

    CPC classification number: A61B18/1477 ,  A61B2018/00755 ,  A61B2018/00821 ,  A61B2018/00875 ,  A61B2018/1253 ,  A61B2018/1475

    Abstract: A device for the ablation of tissue for use with the fingers of a human hand and a radio frequency power supply and controller providing a source of radio frequency energy and controls for controlling the application of radio frequency energy to the device comprising a handle sized so that is adapted to be grasped and supported by the human hand and having proximal and distal extremities. A single conductive needle formed of a conducting material is disposed in the distal extremity of the handle. An edge card is mounted in the handle and has edge mounted contacts with circuitry connected thereto. An edge mount board connector is mounted in the handle and is removably secured to the edge mounted contacts of the edge card. A cable is connected to the edge mount connector and extends from the proximal extremity of the handle and is adapted to be coupled to the radiofrequency power supply and controller. A second printed circuit board is mounted in the handle in a spaced-apart position from the edge card. A flex cable having conductive leads carried thereby extends between the edge card and the printed circuit board and is physically and electrically connected to the edge card. The proximal extremity of the needle is secured to the printed circuit board and makes electrical connections therewith.

    Abstract translation: 用于消除用于人类手指的组织的装置以及提供射频能量源的控制器和控制器，所述控制器控制射频能量对装置的应用，所述手柄的尺寸使得 适于被人的手抓住并支撑，具有近端和远端。 由导电材料形成的单个导电针设置在手柄的远端。 边缘卡安装在手柄中，并且具有与其连接的电路的边缘安装的触点。 边缘安装板连接器安装在手柄中，并可拆卸地固定到边缘卡的边缘安装的触点上。 电缆连接到边缘安装连接器并从手柄的近端延伸并适于耦合到射频电源和控制器。 第二印刷电路板以与边缘卡片隔开的位置安装在手柄中。 由此承载的具有导电引线的柔性电缆在边缘卡和印刷电路板之间延伸并且物理地和电连接到边缘卡。 针的近端被固定到印刷电路板并与其电连接。

    Treatment of urinary incontinence and other disorders by application of energy and drugs
    182.
    发明授权
    Treatment of urinary incontinence and other disorders by application of energy and drugs 有权
    通过应用能量和药物治疗尿失禁和其他疾病

    公开(公告)号：US06692490B1

    公开(公告)日：2004-02-17

    申请号：US09407658

    申请日：1999-09-28

    Applicant: Stuart D. Edwards

    Inventor： Stuart D. Edwards

    IPC: A61B1818

    CPC classification number: A61F5/0026 ,  A61B18/02 ,  A61B18/1477 ,  A61B18/1485 ,  A61B18/1492 ,  A61B18/18 ,  A61B18/24 ,  A61B2017/00084 ,  A61B2017/22062 ,  A61B2018/00029 ,  A61B2018/00065 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00232 ,  A61B2018/00238 ,  A61B2018/00261 ,  A61B2018/00267 ,  A61B2018/00482 ,  A61B2018/00494 ,  A61B2018/00505 ,  A61B2018/00517 ,  A61B2018/00523 ,  A61B2018/00654 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00898 ,  A61B2018/1467 ,  A61B2018/1472 ,  A61B2090/0436 ,  A61B2090/3614 ,  A61B2218/002 ,  A61B2218/007 ,  A61M25/1011 ,  A61M2025/105 ,  A61M2210/1053 ,  A61N1/06 ,  A61N1/36007 ,  A61N1/36017 ,  A61N5/0601 ,  A61N5/062 ,  A61N7/02 ,  A61N2005/061

    Abstract: The invention provides a method and system for treating disorders of the genito-urinary tract and other disorders in other parts of the body. A particular treatment can include one or more of, or some combination of ablation, nerve modulation, three-dimensional tissue shaping, drug delivery, mapping, stimulating, shrinking (by creation of a pattern of thermal lesions) and reducing strain on structures by altering the geometry thereof and providing bulk to particularly defined regions. The particular body structures or tissues can include one or more of, or some combination of regions, including the bladder, esophagus, vagina, penis, larynx, pharynx, aortic arch, abdominal aorta, thoracic aorta, large intestine, small intestine, sinus, auditory canal, uterus, vas deferens, trachea and all associated sphincters. In one aspect of the invention, a catheter is deployed in the body. It may enter the body via a natural orifice, a stoma, or a surgically created opening that is made for the purpose of inserting the catheter. Insertion may be facilitated with the use of a guide wire or a generic support structure or visualization apparatus. In second aspect of the invention, the treatment can include application of energy and substances to effect changes in the target tissue. Types of energy that can be applied include radiofrequency, laser, microwave, infrared waves, ultrasound or some combination thereof. Types of substances that can be applied include pharmaceutical agents such as analgesics, antibiotics and anti-inflammatory drugs, bulking agents such as biologically nonreactive particles, cooling fluids or dessicants such as liquid nitrogen for use in cryo-based treatments.

    Abstract translation: 本发明提供了一种治疗身体其他部位的泌尿系泌尿系疾病和其他疾病的方法和系统。 特定治疗可以包括消融，神经调节，三维组织形成，药物递送，映射，刺激，收缩（通过产生热病变的模式）中的一种或多种或一些组合，并通过改变减少结构上的应变 其几何形状并且向特别限定的区域提供体积。 特定的身体结构或组织可以包括一些或多个区域，包括膀胱，食管，阴道，阴茎，喉，咽，主动脉弓，腹主动脉，胸主动脉，大肠，小肠，窦， 听觉器官，子宫，输精管，气管和所有相关的括约肌。 在本发明的一个方面，导管部署在体内。 它可以通过自然孔，造口或外科手术创建的开口进入身体，该开口用于插入导管。 通过使用导丝或通用支撑结构或可视化装置可以促进插入。 在本发明的第二方面，治疗可以包括施加能量和物质以实现目标组织的变化。 可应用的能量类型包括射频，激光，微波，红外波，超声波或其某些组合。 可以应用的物质的类型包括药剂如镇痛药，抗生素和抗炎药，膨胀剂如生物非反应性颗粒，冷却液或干燥剂如液氮，用于低温治疗。

    Treating body tissue by applying energy and substances with a retractable catheter and contained cooling element
    186.
    发明授权
    Treating body tissue by applying energy and substances with a retractable catheter and contained cooling element 有权
    通过用可伸缩导管施加能量和物质来处理身体组织，并容纳冷却元件

    公开(公告)号：US06425853B1

    公开(公告)日：2002-07-30

    申请号：US09339473

    申请日：1999-06-23

    Applicant: Stuart D. Edwards

    Inventor： Stuart D. Edwards

    IPC: A61F200

    CPC classification number: A61B18/1477 ,  A61B18/1485 ,  A61B2018/00553

    Abstract: The invention provides a method and system for treatment for body structures, especially internal body structures involving unwanted features or other disorders, that does not require relatively invasive surgery, and is not subject to other drawbacks noted with regard to the known art. A relatively minimally invasive catheter including a contained cooling element is inserted into the body. The distal and proximal end of the catheter are extended or retracted or some combination thereof so as to achieve optimal delivery of treatment. Treatment of the body structures is applied using the electrodes embedded in the cooling element, and the unwanted features or disorders are relatively cured using the applied treatments. In a preferred embodiment, the applied treatments can include application of energy or substances, including application (such as of radio frequency energy, microwave energy, or laser or other electromagnetic energy) or substances (such as collagen or other bulking, plumping, or shaping agents; saline or other energy-receiving electrolytes; astringents or other debulking, reducing, or shaping agents; antibiotics or other bioactive, chemoactive, or radioactive compounds). In a preferred embodiment, more than one applied treatment can be performed, either in conjunction, in parallel, or seriatim, so as to achieve a combined effect more substantial than any one individual such applied treatment.

    Abstract translation: 本发明提供了一种用于身体结构的治疗方法和系统，特别是涉及不需要的特征或其他疾病的内部身体结构，其不需要相对侵入性的手术，并且不会受到关于已知技术的其他缺点的影响。 将包含冷却元件的相对微创的导管插入体内。 导管的远端和近端延伸或缩回，或其某些组合，以达到治疗的最佳输送。 使用嵌入冷却元件中的电极来施加身体结构的治疗，并且使用所施加的治疗相对固化不想要的特征或障碍。 在优选实施例中，所应用的处理可以包括能量或物质的应用，包括应用（诸如射频能量，微波能量或激光或其它电磁能）或物质（诸如胶原或其它填充，填充或成形 漱口剂或其他减压剂，还原剂或成型剂;抗生素或其他生物活性，化学活性或放射性化合物）。 在一个优选的实施方案中，多个施用的治疗可以结合，并行或连续进行，以便达到比任何一个个体更加实质的组合效果。

    Integrated cardiac mapping and ablation probe
    190.
    发明授权
    Integrated cardiac mapping and ablation probe 失效
    集成心脏图谱和消融探针

    公开(公告)号：US5964753A

    公开(公告)日：1999-10-12

    申请号：US3087

    申请日：1998-01-05

    Applicant: Stuart D. Edwards

    Inventor： Stuart D. Edwards

    IPC: A61B18/14 ,  A61N1/06 ,  A61B17/39 ,  A61N5/02

    CPC classification number: A61N1/06 ,  A61B18/1492 ,  A61B18/1815 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2018/1253 ,  A61B2218/002

    Abstract: A probe for cardiac diagnosis and/or treatment has a catheter tube. The distal end of the catheter tube carries first and second electrode elements. The probe includes a mechanism for steering the first electrode element relative to the second electrode element so that the user can move the first electrode element into and out of contact with endocardial tissue without disturbing the contact of the second electrode element with endocardial tissue, even through the two electrode elements are carried on a common catheter tube. The distal end can carry a three dimensional structure having an open interior area. One of electrode elements can be steered through the open interior area of the structure. Electrode elements on the exterior of the structure can be used for surface mapping, while the electrode element inside the structure is steered to ablate tissue.

    Abstract translation: 用于心脏诊断和/或治疗的探针具有导管。 导管管的远端承载第一和第二电极元件。 探针包括用于相对于第二电极元件转向第一电极元件的机构，使得使用者可以将第一电极元件移入和脱离与心内膜组织的接触，而不会干扰第二电极元件与心内膜组织的接触，甚至通过 两个电极元件被携带在公共导管上。 远端可以承载具有敞开内部区域的三维结构。 电极元件之一可以通过结构的开放内部区域转向。 结构外部的电极元件可用于表面映射，而结构内的电极元件被转向以消融组织。

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