-
公开(公告)号：US20200247101A1
公开(公告)日：2020-08-06
申请号：US16675838
申请日：2019-11-06
Applicant: Industrial Technology Research Institute
Inventor： Hsin-Hsin SHEN , Yu-Chi WANG , Ming-Chia YANG , Yu-Bing LIOU , Wei-Hong CHANG , Yun-Han LIN , Hsin-Yi HSU , Yun-Chung TENG , Chia-Jung LU , Yi-Hsuan LEE , Jian-Wei LIN , Kun-Mao KUO , Ching-Mei CHEN
Abstract: A method for preparing a bifunctional film, including: (a) drying a first polymer solution to form a film to form an anti-adhesion layer; and (b) drying a second polymer solution over the anti-adhesion layer to form a film to form an attachment layer. The first polymer solution includes a first hydrophobic solution and a first hydrophilic solution, and in the first polymer solution, the weight ratio of the solute of the first hydrophobic solution to the solute of the first hydrophilic solution 1:0.01-1. Moreover, the second polymer solution consists of a second hydrophilic solution.
-
12.发明申请公开(公告)号：US20190192437A1
公开(公告)日：2019-06-27
申请号：US15855260
申请日：2017-12-27
Applicant: Industrial Technology Research Institute
Inventor： Hsin-Hsin SHEN , Wen-Shiang CHEN , Chueh-Hung WU , Ming-Kuan SUN , Yu-Chi WANG , Sen-Lu CHEN , Wei-Lin YU , Lih-Tao HSU , Shih-Ping LIN
IPC: A61K9/14 , A61K9/06 , A61K35/16 , A61K35/19 , A61K31/704 , A61K38/18 , A61K38/38 , A61K41/00 , A61M37/00
CPC classification number: A61K9/146 , A61K9/06 , A61K9/145 , A61K31/704 , A61K35/16 , A61K35/19 , A61K38/1841 , A61K38/385 , A61K41/0047 , A61M37/0092 , A61M2037/0007
Abstract: The disclosure provides a powder form and a hydrogel composition for alleviating degenerative joint and tendon tear. The powder form consists essentially of a 120-380 parts by weight biodegradable copolymer; 15-75 parts by weight urea; and 100 parts by weight platelet-rich plasma; wherein the biodegradable copolymer has a structure of formula (I) or formula (II): wherein A comprises a hydrophilic polyethylene glycol polymer; B comprises a hydrophobic polyester polymer; BOX is bifunctional group monomer of 2, 2′-bis(2-oxazoline) used for coupling the blocks AB or BAB; and n is an integer greater than or equal to 0.
-
公开(公告)号：US20190010483A1
公开(公告)日：2019-01-10
申请号：US16137925
申请日：2018-09-21
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventor： Pei-Yi TSAI , Chih-Hung CHEN , Yi-Hung LIN , Chih-Chieh HUANG , Hsin-Hsin SHEN , Liang-Yin KE , Chu-Huang CHEN
Abstract: A method for ex vivo treating blood or plasma is provided. The method includes (a) ex vivo contacting a blood or plasma with an enzyme composition to react the enzyme composition with the blood or plasma, wherein the enzyme composition is capable of eliminating electronegative low-density lipoprotein from the blood or plasma by the activity of the enzyme composition, and the enzyme composition is selected from a group consisting of: a first enzyme for eliminating a glycan residue of an electronegative low-density lipoprotein (LDL); a second enzyme for eliminating ceramide carried by a electronegative low-density lipoprotein (LDL); and a combination thereof; and (b) terminating contact between the blood or plasma and the enzyme composition to terminate the reaction of the enzyme composition with the blood or plasma.
-
公开(公告)号：US20180200403A1
公开(公告)日：2018-07-19
申请号：US15850902
申请日：2017-12-21
Applicant: Industrial Technology Research Institute
Inventor： Wei-Hong CHANG , Ming-Chia YANG , Yun-Han LIN , Kun-Mao KUO , Yu-Chi WANG , Hsin-Hsin SHEN , Li-Jie LIN
CPC classification number: A61L24/043 , A61B17/04 , A61B17/06166 , A61B17/1114 , A61B2017/00004 , A61B2017/00526 , A61B2017/00575 , A61B2017/00597 , A61B2017/00659 , A61B2017/00818 , A61B2017/00938 , A61B2017/00942 , A61B2017/00964 , A61B2017/0495 , A61B2017/1132 , A61F13/15 , A61L24/0042 , A61L24/0084 , A61L24/0094 , C08L67/04
Abstract: The present disclosure provides a film composed of a polymer mixture, wherein the polymer mixture includes: a hydrophobic composition including polycaprolactone (PCL); and at least one hydrophilic polymer selected from a group consisting of alginate, gelatin, hyaluronic acid, polyvinyl alcohol (PVA), carboxymethyl cellulose (CMC), polyethylene glycol (PEG), collagen, demineralized bone matrix (DBM), bone morphogenetic protein (BMP), albumin, chitosan, fibrin, polyoxyethylene, polyvinylpyrrolidone, wherein the weight ratio of the hydrophobic composition to the hydrophilic polymer is about 1:0.01-100, and wherein the film has the effect of preventing leakage from a surgical wound or a diffuse wound.
-
公开(公告)号：US20150150557A1
公开(公告)日：2015-06-04
申请号：US14555251
申请日：2014-11-26
Inventor： Pei-Yi TSAI , Chih-Chieh HUANG , Yi-Hung WEN , Hsin-Hsin SHEN , Yi-Hung LIN , De-Yau LIN , Jui-Sheng SUN , Chuan-Sheng CHUANG , An-Li CHEN , Ching-Chih LIN
IPC: A61B17/08
CPC classification number: A61B17/686 , A61F2/0811 , A61F2002/0835 , A61F2002/0864
Abstract: A bionic fixing apparatus is provided. The bionic fixing apparatus includes a body having a through hole and at least one slit. The through hole penetrates the body from the top surface to the bottom surface to form a top opening and a bottom opening. An inner diameter of the top opening is larger than an inner diameter of the bottom opening. The slit is connected to the bottom opening and extends upwardly from the bottom surface of the body, such that the body has a flexible bottom portion.
Abstract translation: 提供仿生定影装置。 仿生定影装置包括具有通孔和至少一个狭缝的主体。 通孔从上表面穿透到底面，形成顶部开口和底部开口。 顶部开口的内径大于底部开口的内径。 狭缝连接到底部开口并从主体的底部表面向上延伸，使得主体具有柔性底部。
-
Patent Agency Ranking
公开(公告)号：US20150147722A1
公开(公告)日：2015-05-28
申请号：US14555204
申请日：2014-11-26
Inventor： Pei-Yi TSAI , Chih-Chieh HUANG , Yi-Hung WEN , Hsin-Hsin SHEN , Yi-Hung LIN , De-Yau LIN , Jui-Sheng SUN , Chuan-Sheng CHUANG , An-Li CHEN , Ching-Chih LIN
CPC classification number: A61B17/8625 , A61B17/72 , A61C8/0018 , A61C8/0022 , A61C8/0037 , A61C2008/0046 , A61F2/442
Abstract: A bionic fixing apparatus is provided. The bionic fixing apparatus includes a flexible portion having at least one trench. The trench is disposed on the surface of the flexible portion and has a first end and a second end. An interval is disposed between the first end and the second end. The trench is disposed for spreading the stress applied on the bionic fixing apparatus and preventing stress concentration and stress shielding.
Abstract translation: 提供仿生定影装置。 仿生定影装置包括具有至少一个沟槽的柔性部分。 沟槽设置在柔性部分的表面上并具有第一端和第二端。 间隔设置在第一端和第二端之间。 沟槽设置用于扩展施加在仿生定影装置上的应力，并且防止应力集中和应力屏蔽。
-
公开(公告)号：US20220204772A1
公开(公告)日：2022-06-30
申请号：US17561133
申请日：2021-12-23
Applicant: Industrial Technology Research Institute
Inventor： Yun-Chung TENG , Jen-Huang HUANG , Ying-Wen SHEN , Yu-Bing LIOU , Hsin-Yi HSU , Li-Hsin LIN , Yuchi WANG , Hsin-Hsin SHEN
Abstract: A bioprintable material is provided. The bioprintable material includes a hydrogel and microfilaments mixed in the hydrogel. The hydrogel includes a first collagen. The microfilament includes a second collagen. The diameter of the microfilament is ranging from 5 microns to 200 microns. The weight ratio of the microfilaments to the first collagen is ranging from 0.01:1 to 10:1.
-
公开(公告)号：US20220175432A1
公开(公告)日：2022-06-09
申请号：US17112573
申请日：2020-12-04
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventor： Hsin-Hsin SHEN , Pei-I TSAI , Kuo-Yi YANG , Fang-Jie JANG , An-Li CHEN , Shih-Ping LIN , Chih-Chieh HUANG , Yi-Hung WEN , Wei-Lun FAN , Shin-I HUANG
IPC: A61B17/86
Abstract: A bone screw includes an external screw thread, an internal supporter structure and a porous layer. The internal supporter structure is inside the external screw thread. The internal supporter structure includes a screw thread supporter or a polygonal wall supporter. The porous layer is on a surface of the internal supporter structure. Therefore, the bone screw has an increased strength and also provides postoperative healing effect.
-
公开(公告)号：US20210322625A1
公开(公告)日：2021-10-21
申请号：US17308547
申请日：2021-05-05
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventor： Hsin-Hsin SHEN , Ming-Chia YANG , Chia-Chi HO , Fang-Jie JANG , Che-Yu OU , Chi-Hsiang LIAO , Brian HSU , Tai-Horng YOUNG
Abstract: The present disclosure provides a method for manufacturing a porous film, including: preparing a polymer mixture solution, wherein the polymer mixture solution includes polycaprolactone and at least one hydrophobic polymer; adding solid particles as a dispersing agent to the polymer mixture solution and mixing the solid particles with the polymer mixture solution, wherein the amount of solid particles added is enough to convert the polymer mixture solution into a solid mixture; drying the solid mixture to form a film; and washing the film with a washing fluid to remove the solid particles from the film to form the porous film, wherein the weight ratio of the polycaprolactone to the at least one hydrophobic polymer is about 1:0.1-10, and wherein the weight ratio of the polycaprolactone and the at least one hydrophobic polymer to the solid particles is about 1:0.01-250.
-
公开(公告)号：US20210196648A1
公开(公告)日：2021-07-01
申请号：US16731979
申请日：2019-12-31
Applicant: Industrial Technology Research Institute
Inventor： Hsin-Hsin SHEN , Yuchi WANG , Li-Hsin LIN , Ming-Chia YANG , Hsiu-Hua HUANG , Liang-Cheng SU , Ying-Hsueh CHAO , Jing-En HUANG
IPC: A61K9/70
Abstract: A drug-containing multilayer film provided. The drug-containing multilayer film includes: a drug-containing layer; and an anti-adhesion layer on a surface of the drug-containing layer. The drug-containing layer is composed of a first composition including a first polymer material and a drug, and the first polymer material includes at least one selected from the group consisting of: polylactic acid (PLA) and polyethylene glycol (PEG), and the weight ratio of the first polymer material to the drug is about 1:0.01-0.3. The anti-adhesion layer is composed of a second composition, and the second composition includes a second polymer material, and the second polymer material includes at least one selected from the group consisting of polylactic acid and polyethylene glycol.
-
-
-
-
-
-
-
-
-
Search Results
33
records
(took 0.017 seconds)
