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    Rotor assembly including a housing for a sensor array component and methods for using same
    11.
    发明授权
    Rotor assembly including a housing for a sensor array component and methods for using same 有权

    公开(公告)号：US11588381B2

    公开(公告)日：2023-02-21

    申请号：US17011234

    申请日：2020-09-03

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Todd Roswech

    IPC: B01L3/00 ,  H02K11/20 ,  H02K5/10 ,  B04B5/04 ,  C12Q1/6874 ,  F16K99/00 ,  B04B11/04 ,  G01N35/00 ,  G01N35/04

    Abstract: A rotor assembly includes a rotor plate to rotate around a first axis, a bucket attached to the rotor plate and to rotate around a second axis, and a stop plate to rotate around the first axis between an open position and a closed position. When in the closed position, the stop plate engages the bucket to fix an angular position of the bucket relative to a plane of rotation of the rotor assembly. The rotor assembly further includes a housing for a sensor array component, the housing disposed in the bucket and including a solution inlet, a solution outlet, a transfer basin, a solution retainer disposed between the solution outlet and the transfer basin, and a collection reservoir in fluid communication with the transfer basin. The solution inlet and the solution outlet to engage ports of a flow cell of a sensor array.

    Fluid interface to receive removable container
    13.
    发明授权
    Fluid interface to receive removable container 有权

    公开(公告)号：US11214478B2

    公开(公告)日：2022-01-04

    申请号：US17165196

    申请日：2021-02-02

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Todd Roswech ,  Jonathan Schultz ,  Chun Ho

    IPC: B67D7/02 ,  B67D7/76 ,  B01L3/00 ,  G01N35/10

    Abstract: A fluidic interconnect includes a first interface including a liquid port, a gas port, and a cradle; a second interface including a liquid port, a gas port, and a swing bar to engage the cradle, a weight of a container attached to one of the first or second interfaces to drive the liquid port of the first interface into connection with the liquid port of the second interface and the gas port of the first interface into connection with the gas port of the second interface.

    Rotor assembly including a housing for a sensor array component and methods for using same
    14.
    发明授权
    Rotor assembly including a housing for a sensor array component and methods for using same 有权

    公开(公告)号：US10797567B2

    公开(公告)日：2020-10-06

    申请号：US15216991

    申请日：2016-07-22

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Todd Roswech

    IPC: H02K11/20 ,  H02K5/10 ,  B01L3/00 ,  B04B5/04 ,  F16K99/00 ,  C12Q1/6874 ,  B04B11/04 ,  G01N35/00 ,  G01N35/04

    Abstract: A rotor assembly includes a rotor plate to rotate around a first axis, a bucket attached to the rotor plate and to rotate around a second axis, and a stop plate to rotate around the first axis between an open position and a closed position. When in the closed position, the stop plate engages the bucket to fix an angular position of the bucket relative to a plane of rotation of the rotor assembly. The rotor assembly further includes a housing for a sensor array component, the housing disposed in the bucket and including a solution inlet, a solution outlet, a transfer basin, a solution retainer disposed between the solution outlet and the transfer basin, and a collection reservoir in fluid communication with the transfer basin. The solution inlet and the solution outlet to engage ports of a flow cell of a sensor array.

    Fluid interface to receive removable container
    15.
    发明授权
    Fluid interface to receive removable container 有权

    公开(公告)号：US10427928B2

    公开(公告)日：2019-10-01

    申请号：US15259245

    申请日：2016-09-08

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Todd Roswech ,  Jonathan Schultz ,  Chun Ho

    IPC: B67D7/76 ,  B01L3/00 ,  B67D7/02 ,  G01N35/10

    Abstract: A fluidic interconnect includes a first interface including a liquid port, a gas port, and a cradle; a second interface including a liquid port, a gas port, and a swing bar to engage the cradle, a weight of a container attached to one of the first or second interfaces to drive the liquid port of the first interface into connection with the liquid port of the second interface and the gas port of the first interface into connection with the gas port of the second interface.

    Sequencing device
    16.
    发明授权
    Sequencing device 有权

    公开(公告)号：US10240193B2

    公开(公告)日：2019-03-26

    申请号：US15891485

    申请日：2018-02-08

    Applicant: Life Technologies Corporation

    Inventor： Jonathan Schultz ,  Todd Roswech ,  Jon A. Hoshizaki ,  Albert L. Carrillo ,  James A. Ball

    IPC: C12Q1/68 ,  B01L3/00 ,  G01N27/414 ,  G01N35/10 ,  B01F11/00 ,  B01F1/00 ,  B01F5/06 ,  C12Q1/6869 ,  C12Q1/6806

    Abstract: A method of preparing reagents includes inserting a cartridge into an instrument. The cartridge includes a plurality of reagent enclosures disposed in a cavity of the cartridge and exposing a port to an exterior of the cartridge. Each reagent enclosure includes a reagent container including a reagent and an internal cavity defining a compressible volume, an opening defined through the reagent container to the internal cavity. The method further includes connecting a plurality of fluid ports to the openings of the plurality of reagent enclosures; applying a solution through the fluid ports to at least partially fill the plurality of reagent enclosures; and cycling a pressure of the cavity, whereby for each of the reagent enclosures, during increasing pressure, the solution enters the internal cavity of the reagent container, combines with the reagent, and compresses the compressible volume, and during decreasing pressure, the compressible volume decreases and the reagent is ejected through the opening.

    Sequencing device
    20.
    发明授权
    Sequencing device 有权

    公开(公告)号：US10894982B2

    公开(公告)日：2021-01-19

    申请号：US16289508

    申请日：2019-02-28

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Jonathan Schultz ,  Todd Roswech ,  Jon A. Hoshizaki ,  Albert L. Carrillo ,  James A. Ball

    IPC: C12Q1/6869 ,  C12Q1/6806 ,  B01L3/00 ,  G01N27/414 ,  G01N35/10 ,  B01F5/06 ,  B01F11/00 ,  B01F1/00

    Abstract: A method of preparing reagents includes inserting a cartridge into an instrument. The cartridge includes a plurality of reagent enclosures disposed in a cavity of the cartridge and exposing a port to an exterior of the cartridge. Each reagent enclosure includes a reagent container including a reagent and an internal cavity defining a compressible volume, an opening defined through the reagent container to the internal cavity. The method further includes connecting a plurality of fluid ports to the openings of the plurality of reagent enclosures; applying a solution through the fluid ports to at least partially fill the plurality of reagent enclosures; and cycling a pressure of the cavity, whereby for each of the reagent enclosures, during increasing pressure, the solution enters the internal cavity of the reagent container, combines with the reagent, and compresses the compressible volume, and during decreasing pressure, the compressible volume decreases and the reagent is ejected through the opening.

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