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    CORROSION PROTECTION IN TUBING USED IN CHROMATOGRAPHY
    11.
    发明申请
    CORROSION PROTECTION IN TUBING USED IN CHROMATOGRAPHY 审中-公开
    用于色谱中的管道中的腐蚀保护

    公开(公告)号：US20150048015A1

    公开(公告)日：2015-02-19

    申请号：US14382900

    申请日：2013-03-04

    Applicant: Waters Technologies Corporation

    Inventor： Kurt D. Joudrey ,  Trudeau D. Steven ,  Paul Keenan ,  Joseph A. Luongo ,  Daniel J. McCormick ,  Eugene Berthiaume

    IPC: B01D15/22 ,  G01N30/60

    CPC classification number: B01D15/22 ,  B01D15/08 ,  B01D15/40 ,  G01N30/02 ,  G01N30/56 ,  G01N30/60 ,  G01N30/6004 ,  G01N30/6026 ,  G01N2030/027 ,  G01N2030/6013

    Abstract: An apparatus for use in a liquid chromatography system includes a chromatography port and a tubing assembly having a chromatography tube coupled at one end to the chromatography port. The end of the tube has an end face covered with a corrosion-resistant material, for example, gold. The corrosion-resistant nature of the material protects the end of the tube from corrosion or erosion, which improves the quality and reliability of a seal between the end face of the tube and a sealing surface of the port. Alternatively, or in addition to covering the end face of the tube with the corrosion-resistant material, a gasket covered with or made of the corrosion-resistant material can be disposed between the end face of the tube and the port. This gasket extends the reach of the tube to facilitate bottoming out the tube within the port.

    Abstract translation: 用于液相色谱系统的装置包括色谱端口和管组件，该管组件具有在一端与色谱端口相连的色谱管。 管的端部具有覆盖有耐腐蚀材料（例如金）的端面。 材料的耐腐蚀性能保护管的端部不受腐蚀或腐蚀，这提高了管的端面和端口的密封表面之间的密封的质量和可靠性。 或者，或者除了用耐腐蚀材料覆盖管的端面之外，可以在管的端面和端口之间设置由耐腐蚀材料覆盖或由其制成的垫圈。 该垫圈延伸管的到达，以便于在端口内从底部出来。

    SELECT VALVE FOR LIQUID CHROMATOGRAPHY
    12.
    发明申请
    SELECT VALVE FOR LIQUID CHROMATOGRAPHY 审中-公开
    用于液相色谱的选择阀

    公开(公告)号：US20140326664A1

    公开(公告)日：2014-11-06

    申请号：US14359396

    申请日：2012-12-07

    Applicant: Waters Technologies Corporation

    Inventor： Kurt D. Joudrey ,  Maruth Sok

    IPC: B01D15/14 ,  F16K11/02 ,  G01N30/02

    Abstract: A liquid chromatography system includes a pumping system with a selector valve in fluidic communication with a pump inlet. The selector valve switches between a first position, in which the selector valve fluidically couples a solvent reservoir to the pump inlet, and a second position, in which the selector valve fluidically couples a pressurized source of liquefied carbon dioxide (for example) to the pump inlet. The liquid chromatography system can perform as a HPLC system (or as an UPLC system) when the selector valve is in the first position and as a CO2-based chromatography system when the selector valve is in the second position. The selector valve can have a third position in which both the fluidic pathway between the solvent reservoir and the pump inlet and the fluidic pathway between the pressurized source and the pump inlet are blocked. This shut-off position advantageously facilitates system maintenance.

    Abstract translation: 液相色谱系统包括具有与泵入口流体连通的选择阀的泵送系统。 选择阀在其中选择阀将溶剂容器流体耦合到泵入口的第一位置和第二位置之间切换，在第二位置，选择阀将加压的液化二氧化碳源（例如）流体耦合到泵 进口。 当选择阀处于第一位置时，液相色谱系统可以作为HPLC系统（或作为UPLC系统）进行，并且当选择阀处于第二位置时可以作为基于CO 2的色谱系统。 选择阀可以具有第三位置，在该第三位置中，溶剂容器和泵入口之间的流体路径以及加压源和泵入口之间的流体路径均被阻挡。 该关闭位置有利于系统维护。

    CONVECTIVELY CONTROLLED ADIABATIC COLUMN CHAMBER FOR USE IN CHROMATOGRAPHIC SYSTEMS
    15.
    发明申请
    CONVECTIVELY CONTROLLED ADIABATIC COLUMN CHAMBER FOR USE IN CHROMATOGRAPHIC SYSTEMS 审中-公开
    用于色谱系统的连续控制的自动色谱柱

    公开(公告)号：US20170038346A1

    公开(公告)日：2017-02-09

    申请号：US15303328

    申请日：2015-04-10

    Applicant: Waters Technologies Corporation

    Inventor： Joshua A. Shreve ,  Kurt D. Joudrey

    IPC: G01N30/30 ,  F24H9/00 ,  F24H3/08 ,  B01D15/16 ,  B01D53/02

    CPC classification number: G01N30/30 ,  B01D15/161 ,  B01D53/025 ,  F24H3/062 ,  F24H3/081 ,  F24H9/0073 ,  F24H9/1863 ,  F24H9/2071 ,  F24H2240/08 ,  F24H2250/06 ,  G01N2030/3007

    Abstract: A column-conditioning enclosure includes a column chamber adapted to hold one or more chromatography separation columns. A duct system provides an airflow path around the column chamber such that the one or more chromatography separation columns held within the column chamber are isolated from the airflow path. An air mover disposed in the airflow path generates a flow of air within the duct system. A heat exchanger system disposed in the airflow path near the air to exchange heat with the air as the air flows past the heat exchanger system. The air circulates through the duct system around the column chamber, convectively exchanging heat with the column chamber to produce a thermally conditioned environment for the one or more chromatography separation columns held within the column chamber.

    Abstract translation: 柱调节外壳包括适于容纳一个或多个色谱分离柱的柱室。 管道系统提供围绕柱室的气流路径，使得保持在柱室内的一个或多个色谱分离柱与气流路径隔离。 设置在气流路径中的鼓风机在管道系统内产生空气流。 一种热交换器系统，其布置在靠近空气的气流中，随着空气流过热交换器系统而与空气交换热量。 空气循环通过柱室周围的管道系统，与塔室对流地进行热交换，以产生用于保持在塔室内的一个或多个色谱分离柱的热调节环境。

    CARBON DIOXIDE LIQUID PHASE FORMING USING HIGH VOLUME HEAD DISPLACEMENT
    16.
    发明申请
    CARBON DIOXIDE LIQUID PHASE FORMING USING HIGH VOLUME HEAD DISPLACEMENT 审中-公开
    二氧化碳液相形成使用高容量头位移

    公开(公告)号：US20160139092A1

    公开(公告)日：2016-05-19

    申请号：US14898282

    申请日：2014-06-16

    Applicant: WATERS TECHNOLOGIES CORPORATION

    Inventor： Robert Dumas ,  Kurt D. Joudrey ,  Michael R. Jackson

    IPC: G01N30/16 ,  F04B15/06 ,  F04B19/22 ,  F04B53/10 ,  F04B53/08 ,  F04B53/14 ,  F04B53/16 ,  F04B53/06 ,  F04B23/06 ,  F04B49/06

    CPC classification number: G01N30/16 ,  F04B13/00 ,  F04B15/06 ,  F04B15/08 ,  F04B19/22 ,  F04B23/06 ,  F04B49/065 ,  F04B53/06 ,  F04B53/08 ,  F04B53/10 ,  F04B53/14 ,  F04B53/16 ,  F04B2015/0818 ,  G01N30/68 ,  G01N30/7206 ,  G01N30/74 ,  G01N2030/025 ,  G01N2030/027 ,  G01N2030/326

    Abstract: Systems and methods for pumping carbon dioxide in a chromatography system include an actuator that receives and compresses carbon dioxide at or above room temperature at a given pressure to put the carbon dioxide in or near supercritical form. This actuator can be a pre-pump disposed on the intake side of a pumping system. Alternatively, this actuator can be a primary actuator in the pumping system. The actuator includes an intake chamber that receives the carbon dioxide and a movable plunger extending into and closely received by the intake chamber. The plunger has a diameter and stroke length adapted to compress the carbon dioxide received by the intake chamber in sufficient volume at the given pressure to put the carbon dioxide in or near supercritical form at or above room temperature. A metered amount of the carbon dioxide in or near supercritical form can then be pumped.

    Abstract translation: 用于在色谱系统中抽取二氧化碳的系统和方法包括致动器，其在给定压力下接收和压缩室温或室温以上的二氧化碳，以将二氧化碳置于或接近超临界形式。 该致动器可以是设置在泵送系统的进气侧的预泵。 或者，该致动器可以是泵送系统中的主要致动器。 致动器包括进气室，其容纳二氧化碳和可移动的柱塞，该柱塞延伸到进气室中并且紧密地被进气室接收。 柱塞具有直径和冲程长度，其适于在给定压力下以足够的体积压缩由进气室接收的二氧化碳，以将二氧化碳置于室温或室温以上或接近超临界状态。 然后可以泵送超临界形式的或接近超临界形式的计量量的二氧化碳。

    HIGH PRESSURE FITTING FOR A LIQUID CHROMATOGRAPHY SYSTEM
    18.
    发明申请
    HIGH PRESSURE FITTING FOR A LIQUID CHROMATOGRAPHY SYSTEM 审中-公开
    液相色谱系统的高压配件

    公开(公告)号：US20150042089A1

    公开(公告)日：2015-02-12

    申请号：US14382850

    申请日：2013-02-01

    Applicant: Waters Technologies Corporation

    Inventor： Kurt D. Joudrey ,  Sylvain Cormier ,  James Usowicz ,  Emily J. Berg ,  Christopher Seith

    IPC: F16L19/06 ,  G01N30/60

    CPC classification number: F16L19/061 ,  G01N30/6026

    Abstract: A fitting for coupling fluidic paths, such as high pressure fluidic paths in liquid chromatography systems, includes a compression nut, a tube assembly and a compression member. The compression nut has a threaded outer surface to engage a threaded bore of a receiving port and the tube assembly has an outer surface and an end face to contact a sealing surface of the receiving port. The compression member is pre-staked to the outer surface of the tube assembly at a predetermined distance from the end face and has a tapered surface to engage a surface of the receiving port. The predetermined distance permits the tube assembly to be inserted into the receiving port so that the end face makes contact with the sealing surface without the tapered surface engaging a surface of the receiving port and so that the threaded outer surface of the compression nut engages the threaded bore.

    Abstract translation: 用于耦合流体路径（例如液相色谱系统中的高压流体路径）的配件包括压缩螺母，管组件和压缩构件。 压缩螺母具有螺纹外表面以接合接收端口的螺纹孔，并且管组件具有外表面和端面以接触接收端口的密封表面。 压缩构件预先固定在距离端面一预定距离的管组件的外表面上，并且具有锥形表面以接合接收端口的表面。 预定距离允许管组件插入到接收端口中，使得端面与密封表面接触，而锥形表面接合接收端口的表面，并且使得压缩螺母的螺纹外表面接合螺纹 孔。

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