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公开(公告)号：US20130115105A1
公开(公告)日：2013-05-09
申请号：US13657628
申请日：2012-10-22
发明人： Brian D. Tracey , Larry B. Gray , Jason A. Demers , James D. Dale , N. Christopher Perry , Michael J. Wilt , Scott A. Leonard
IPC分类号： A61M1/10
CPC分类号： A61M1/106 , A61F7/12 , A61F2007/0069 , A61F2007/126 , A61M1/1006 , A61M1/1012 , A61M1/1037 , A61M1/1062 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/3626 , A61M1/369 , A61M2205/12 , A61M2205/127 , A61M2205/27 , A61M2205/3334 , A61M2205/3368 , A61M2205/3606 , A61M2205/3653 , A61M2205/502 , F04B43/0054 , F04B43/06 , F04B43/0736 , G01K1/08 , G01K1/16 , G01M3/188
摘要： Embodiments of the present invention relate generally to certain types of reciprocating positive-displacement pumps (which may be referred to hereinafter as “pods,” “pump pods,” or “pod pumps”) used to pump fluids, such as a biological fluid (e.g., blood or peritoneal fluid), a therapeutic fluid (e.g., a medication solution), or a surfactant fluid. The pumps may be configured specifically to impart low shear forces and low turbulence on the fluid as the fluid is pumped from an inlet to an outlet. Such pumps may be particularly useful in pumping fluids that may be damaged by such shear forces (e.g., blood, and particularly heated blood, which is prone to hemolysis) or turbulence (e.g., surfectants or other fluids that may foam or otherwise be damaged or become unstable in the presence of turbulence).
摘要翻译： 本发明的实施例一般涉及用于泵送流体的某些类型的往复式正排量泵（以下称为“舱”，“泵舱”或“舱泵”），例如生物流体 例如血液或腹膜液），治疗液（例如药物溶液）或表面活性剂流体。 泵可以被特别地构造成当流体从入口泵送到出口时在液体上施加低剪切力和低湍流。 这种泵可能特别可用于泵送可能被这种剪切力（例如，血液，特别是加热的血液，易于溶血）或湍流（例如，可能发泡或以其他方式损坏的冲洗液或其他流体） 在湍流的存在下变得不稳定）。
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公开(公告)号：US12064540B2
公开(公告)日：2024-08-20
申请号：US18452516
申请日：2023-08-18
CPC分类号： A61M1/1601 , A61M1/154 , A61M1/155 , A61M1/15625 , A61M1/1565 , A61M1/16 , A61M1/1621 , A61M1/1654 , A61M1/1694 , A61M1/267 , A61M1/3401 , A61M1/341 , A61M1/3413 , A61M1/3424 , A61M1/3609 , A61M1/3621 , A61M1/36224 , A61M1/36225 , A61M1/362263 , A61M1/362265 , A61M1/362266 , A61M1/3623 , A61M1/3638 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3672 , A61M1/1561 , A61M1/362261 , A61M2205/07 , A61M2205/12 , A61M2205/123 , A61M2205/125 , A61M2205/128 , A61M2205/15 , A61M2205/16 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/36 , A61M2205/505 , A61M2205/82 , A61M2205/8218 , A61M2205/8225 , Y10T137/87893
摘要： The present invention generally relates to hemodialysis and similar dialysis systems, including a variety of systems and methods that would make hemodialysis more efficient, easier, and/or more affordable. One aspect of the invention is generally directed to new fluid circuits for fluid flow. In one set of embodiments, a hemodialysis system may include a blood flow path and a dialysate flow path, where the dialysate flow path includes one or more of a balancing circuit, a mixing circuit, and/or a directing circuit. Preparation of dialysate by the preparation circuit, in some instances, may be decoupled from patient dialysis. In some cases, the circuits are defined, at least partially, within one or more cassettes, optionally interconnected with conduits, pumps, or the like. In one embodiment, the fluid circuit and/or the various fluid flow paths may be at least partially isolated, spatially and/or thermally, from electrical components of the hemodialysis system. In some cases, a gas supply may be provided in fluid communication with the dialysate flow path and/or the dialyzer that, when activated, is able to urge dialysate to pass through the dialyzer and urge blood in the blood flow path back to the patient. Such a system may be useful, for example, in certain emergency situations (e.g., a power failure) where it is desirable to return as much blood to the patient as possible. The hemodialysis system may also include, in another aspect of the invention, one or more fluid handling devices, such as pumps, valves, mixers, or the like, which can be actuated using a control fluid, such as air. In some cases, the control fluid may be delivered to the fluid handling devices using an external pump or other device, which may be detachable in certain instances. In one embodiment, one or more of the fluid handling devices may be generally rigid (e.g., having a spheroid shape), optionally with a diaphragm contained within the device, dividing it into first and second compartments.
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公开(公告)号：US12044229B2
公开(公告)日：2024-07-23
申请号：US18357076
申请日：2023-07-21
发明人： Brian D. Tracey , Larry B. Gray , Jason A. Demers , James D. Dale , N. Christopher Perry , Michael J. Wilt , Scott A. Leonard
IPC分类号： F04B43/073 , A61M1/16 , A61M1/28 , A61M1/36 , F04B7/02 , F04B23/06 , F04B39/12 , F04B39/14 , F04B43/00 , F04B53/16 , F04B53/22
CPC分类号： F04B43/073 , A61M1/16 , A61M1/1605 , A61M1/1656 , A61M1/287 , A61M1/362227 , A61M1/36225 , A61M1/362265 , F04B7/02 , F04B23/06 , F04B39/12 , F04B39/123 , F04B39/14 , F04B43/0081 , F04B43/0736 , F04B53/16 , F04B53/22 , A61M1/362263 , A61M2205/12 , A61M2205/128 , A61M2205/3317 , A61M2205/3324 , A61M2205/3368
摘要： Embodiments of the present invention relate generally to certain types of reciprocating positive-displacement pumps (which may be referred to hereinafter as “pods,” “pump pods,” or “pod pumps”) used to pump fluids, such as a biological fluid (e.g., blood or peritoneal fluid), a therapeutic fluid (e.g., a medication solution), or a surfactant fluid. The pumps may be configured specifically to impart low shear forces and low turbulence on the fluid as the fluid is pumped from an inlet to an outlet. Such pumps may be particularly useful in pumping fluids that may be damaged by such shear forces (e.g., blood, and particularly heated blood, which is prone to hemolysis) or turbulence (e.g., surfactants or other fluids that may foam or otherwise be damaged or become unstable in the presence of turbulence).
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公开(公告)号：US12044228B2
公开(公告)日：2024-07-23
申请号：US18138711
申请日：2023-04-24
IPC分类号： F04B43/06 , A61M1/14 , A61M1/16 , A61M60/113 , A61M60/268 , A61M60/37 , A61M60/427 , A61M60/523 , A61M60/546 , A61M60/847 , A61M60/851 , F04B9/109 , F04B13/02 , F04B43/02 , F04B43/073 , F04B45/053 , F04B53/10 , F16K99/00 , A61M60/43
CPC分类号： F04B43/06 , A61M1/14 , A61M1/154 , A61M1/155 , A61M1/15625 , A61M1/1563 , A61M1/1565 , A61M1/16 , A61M1/1601 , A61M1/1639 , A61M1/1656 , A61M1/1658 , A61M1/166 , A61M60/113 , A61M60/268 , A61M60/37 , A61M60/427 , A61M60/523 , A61M60/546 , A61M60/847 , A61M60/851 , F04B9/109 , F04B13/02 , F04B43/02 , F04B43/073 , F04B43/0733 , F04B45/053 , F04B45/0536 , F04B53/106 , F04B53/1062 , F16K99/0015 , A61M1/153 , A61M60/43 , A61M2205/12 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3368 , Y10T137/0329 , Y10T137/2521 , Y10T137/2931 , Y10T137/7879 , Y10T137/85978 , Y10T137/86139
摘要： A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.
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公开(公告)号：US20240123132A1
公开(公告)日：2024-04-18
申请号：US18394189
申请日：2023-12-22
发明人： Kevin L. Grant , Michael J. Wilt , Brian D. Tracey , Brett A. Rudolf , David E. Collins , Lisa A. Gustin , James D. Dale , Jesse T. Bodwell
CPC分类号： A61M1/3653 , A61M1/14 , A61M1/1658 , A61M1/1682 , A61M1/1686 , A61M1/362227 , A61M1/36225 , A61M1/362261 , A61M1/362265 , A61M1/3643 , A61M1/3644 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3656 , A61M1/367 , A61M1/3672 , A61M1/168 , A61M1/36224 , A61M1/362266 , A61M2205/12 , A61M2205/121 , A61M2205/128
摘要： A drain cassette for a dialysis unit has a fluid channel between venous and arterial connection ports, and a valve may controllably open and close fluid communication between a drain outlet port and the venous connection port or the arterial connection port. A blood circuit assembly and drain cassette may be removable from the dialysis unit, e.g., by hand and without the use of tools. A blood circuit assembly may include a single, unitary member that defines portions of a pair of blood pumps, control valves, channels to accurately position flexible tubing for an occluder, an air trap support, and/or other portions of the assembly. A blood circuit assembly engagement device may assist with retaining a blood circuit assembly on the dialysis unit, and/or with removal of the assembly. An actuator may operate a retainer element and an ejector element that interact with the assembly.
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公开(公告)号：US11890403B2
公开(公告)日：2024-02-06
申请号：US17026804
申请日：2020-09-21
发明人： Kevin L. Grant , Michael J. Wilt , Brian D. Tracey , Brett A. Rudolf , David E. Collins , Lisa A. Gustin , James D. Dale , Jesse T. Bodwell
CPC分类号： A61M1/3653 , A61M1/14 , A61M1/1658 , A61M1/1682 , A61M1/1686 , A61M1/365 , A61M1/367 , A61M1/3643 , A61M1/3644 , A61M1/3647 , A61M1/3649 , A61M1/3652 , A61M1/3656 , A61M1/3672 , A61M1/36225 , A61M1/362227 , A61M1/362261 , A61M1/362265 , A61M1/168 , A61M1/36224 , A61M1/362266 , A61M2205/12 , A61M2205/121 , A61M2205/128
摘要： A drain cassette for a dialysis unit has a fluid channel between venous and arterial connection ports, and a valve may controllably open and close fluid communication between a drain outlet port and the venous connection port or the arterial connection port. A blood circuit assembly and drain cassette may be removable from the dialysis unit, e.g., by hand and without the use of tools. A blood circuit assembly may include a single, unitary member that defines portions of a pair of blood pumps, control valves, channels to accurately position flexible tubing for an occluder, an air trap support, and/or other portions of the assembly. A blood circuit assembly engagement device may assist with retaining a blood circuit assembly on the dialysis unit, and/or with removal of the assembly. An actuator may operate a retainer element and an ejector element that interact with the assembly.
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公开(公告)号：US11779691B2
公开(公告)日：2023-10-10
申请号：US17107495
申请日：2020-11-30
IPC分类号： F04B7/02 , F04B53/10 , F04B43/06 , A61M1/16 , A61M1/28 , F04B9/109 , F04B13/02 , F04B23/06 , F04B41/06 , F04B43/00 , F04B43/073 , F04B45/02 , F04B45/053 , F04B49/22 , F04B53/06 , F04B53/16 , F17D3/00 , F04B49/02 , A61M60/43
CPC分类号： A61M1/1639 , A61M1/16 , A61M1/1605 , A61M1/1656 , A61M1/1664 , A61M1/1666 , A61M1/287 , F04B7/02 , F04B9/109 , F04B13/02 , F04B23/06 , F04B41/06 , F04B43/00 , F04B43/06 , F04B43/0736 , F04B45/02 , F04B45/0536 , F04B49/02 , F04B49/22 , F04B53/06 , F04B53/10 , F04B53/16 , F17D3/00 , A61M60/43 , A61M2205/12 , A61M2205/128 , A61M2205/3317 , A61M2205/3324 , A61M2205/3368 , Y10T137/0324 , Y10T137/0379 , Y10T137/2521 , Y10T137/85978 , Y10T137/86139
摘要： A pumping cassette including a housing having at least two inlet fluid lines and at least two outlet fluid lines. At least one balancing pod within the housing and in fluid connection with the fluid paths. The balancing pod balances the flow of a first fluid and the flow of a second fluid such that the volume of the first fluid equals the volume of the second fluid. The balancing pod also includes a membrane that forms two balancing chambers. Also included in the cassette is at least two reciprocating pressure displacement membrane pumps. The pumps are within the housing and they pump the fluid from a fluid inlet to a fluid outlet line and pump the second fluid from a fluid inlet to a fluid outlet.
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公开(公告)号：US11633526B2
公开(公告)日：2023-04-25
申请号：US17366609
申请日：2021-07-02
IPC分类号： A61M1/16 , A61M1/14 , A61M60/113 , A61M60/268 , A61M60/37 , A61M60/427 , A61M60/847 , A61M60/851 , F04B9/109 , F04B13/02 , F04B43/02 , F04B43/06 , F04B43/073 , F04B45/053 , F04B53/10 , F16K99/00 , A61M60/546 , A61M60/523 , A61M60/43
摘要： A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.
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公开(公告)号：US11419965B2
公开(公告)日：2022-08-23
申请号：US16573676
申请日：2019-09-17
IPC分类号： A61M1/16 , A61M1/28 , F04B7/02 , F04B9/109 , F04B13/02 , F04B23/06 , F04B41/06 , F04B43/00 , F04B43/073 , F04B45/02 , F04B45/053 , F04B49/22 , F04B53/06 , F04B53/10 , F04B53/16 , F17D3/00 , F04B49/02 , A61M60/40 , A61M60/43 , A61M60/113 , A61M60/268 , A61M60/892 , A61M60/894
摘要： A pump cassette is disclosed. The pump cassette includes a housing having at least one fluid inlet line and at least one fluid outlet line. The cassette also includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps a fluid from the fluid inlet line to the fluid outlet line. A hollow spike is also included on the housing as well as at least one metering pump. The metering pump is fluidly connected to the hollow spike on the housing and to a metering pump fluid line. The metering pump fluid line is fluidly connected to the fluid outlet line.
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公开(公告)号：US20220133968A1
公开(公告)日：2022-05-05
申请号：US17493758
申请日：2021-10-04
摘要： The present invention generally relates to hemodialysis and similar dialysis systems, including a variety of systems and methods that would make hemodialysis more efficient, easier, and/or more affordable. One aspect of the invention is generally directed to new fluid circuits for fluid flow. In one set of embodiments, a hemodialysis system may include a blood flow path and a dialysate flow path, where the dialysate flow path includes one or more of a balancing circuit, a mixing circuit, and/or a directing circuit. Preparation of dialysate by the preparation circuit, in some instances, may be decoupled from patient dialysis. In some cases, the circuits are defined, at least partially, within one or more cassettes, optionally interconnected with conduits, pumps, or the like. In one embodiment, the fluid circuit and/or the various fluid flow paths may be at least partially isolated, spatially and/or thermally, from electrical components of the hemodialysis system. In some cases, a gas supply may be provided in fluid communication with the dialysate flow path and/or the dialyzer that, when activated, is able to urge dialysate to pass through the dialyzer and urge blood in the blood flow path back to the patient. Such a system may be useful, for example, in certain emergency situations (e.g., a power failure) where it is desirable to return as much blood to the patient as possible. The hemodialysis system may also include, in another aspect of the invention, one or more fluid handling devices, such as pumps, valves, mixers, or the like, which can be actuated using a control fluid, such as air. In some cases, the control fluid may be delivered to the fluid handling devices using an external pump or other device, which may be detachable in certain instances. In one embodiment, one or more of the fluid handling devices may be generally rigid (e.g., having a spheroid shape), optionally with a diaphragm contained within the device, dividing it into first and second compartments.
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