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公开(公告)号：US10132794B2
公开(公告)日：2018-11-20
申请号：US15561014
申请日：2016-09-14
Applicant: ESSENLIX CORPORATION
Inventor： Stephen Y. Chou , Wei Ding
Abstract: The present invention is related to the field of bio/chemical sensing, assays and applications. Particularly, the present invention is related to collecting a small amount of a vapor condensate sample (e.g. the exhaled breath condensate (EBC) from a subject of a volume as small as 10 fL (femto-Liter) in a single drop), preventing or significantly reducing an evaporation of the collected vapor condensate sample, analyzing the sample, analyzing the sample by mobile-phone, and performing such collection and analysis by a person without any professionals.
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公开(公告)号：US20250150692A1
公开(公告)日：2025-05-08
申请号：US18915106
申请日：2024-10-14
Applicant: Essenlix Corporation
Inventor： Stephen Y. Chou , Wei Ding , Yufan Zhang , Ji Qi , Jun Tian , Wei Dong
Abstract: The present disclosure relates to devices, apparatus and methods of improving the accuracy of an image-based assay. One aspect of the present invention is to sandwich a sample between two plates and add reference marks in the sample areas of the plates, with at least one of the geometric and/optical properties of the reference marks being predetermined and known, and taking images of the sample with the reference marks, and applying a machine learning model in the analysis of the image-based assay.
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公开(公告)号：US12248533B2
公开(公告)日：2025-03-11
申请号：US18101109
申请日：2023-01-24
Applicant: Essenlix Corporation
Inventor： Xing Li , Wu Chou , Stephen Y. Chou , Wei Ding , Ji Qi
IPC: G06F18/214 , G06N3/042 , G06N3/045 , G06N3/08 , G06T5/50 , G06T7/00 , G06T7/11 , G06T7/70 , G06V10/22
Abstract: The present disclosure relates to devices, apparatus and methods of improving the accuracy of image-based assay, that uses imaging system having uncertainties or deviations (imperfection) compared with an ideal imaging system. One aspect of the present invention is to add the monitoring marks on the sample holder, with at least one of their geometric and/optical properties of the monitoring marks under predetermined and known, and taking images of the sample with the monitoring marks, and train a machine learning model using the images with the monitoring mark.
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公开(公告)号：US20240410885A1
公开(公告)日：2024-12-12
申请号：US18809047
申请日：2024-08-19
Applicant: Essenlix Corporation
Inventor： Stephen Y. Chou , Wei Ding , Yufan Zhang , Ji Qi
IPC: G01N33/543 , G01N1/40 , G01N21/64 , G01N21/65 , G01N21/69 , G01N21/76 , G01N33/558
Abstract: The present invention provides, among other things, QMAX card based assays in different forms for various analytes, offering simpler, fast, more sensitive assaying.
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公开(公告)号：US20240361247A1
公开(公告)日：2024-10-31
申请号：US18598299
申请日：2024-03-07
Applicant: Essenlix Corporation
Inventor： Stephen Y. Chou , Wei Ding , Yufan Zhang , Ji Qi , Ji Li
IPC: G01N21/65 , G01N21/64 , G01N21/66 , G01N33/543 , G01N33/58
CPC classification number: G01N21/65 , G01N21/64 , G01N21/66 , G01N33/54366 , G01N33/582 , G01N2201/06113
Abstract: A homogeneous assay method that employs a device is provided. In some embodiments, the device contains a pair of plates that can be opened and closed. The sample is placed between two plates. In some embodiments, the thickness of the sample in a closed configuration, the concentration of labels, and amplification factor of the amplification surface are configured to make the label(s) bound on the amplification surface visible without washing away of the unbound labels.
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Patent Agency Ranking
公开(公告)号：US12066434B2
公开(公告)日：2024-08-20
申请号：US16484678
申请日：2018-02-08
Applicant: Essenlix Corporation
Inventor： Stephen Y. Chou , Wei Ding , Yufan Zhang , Ji Qi
IPC: G01N33/543 , G01N1/40 , G01N21/64 , G01N21/65 , G01N21/69 , G01N21/76 , G01N33/558
CPC classification number: G01N33/54366 , G01N1/405 , G01N21/648 , G01N21/65 , G01N21/69 , G01N21/76 , G01N33/558
Abstract: The present invention provides, among other things, QMAX card based assays in different forms for various analytes, offering simpler, fast, more sensitive assaying.
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公开(公告)号：US12044603B2
公开(公告)日：2024-07-23
申请号：US17752823
申请日：2022-05-24
Applicant: Essenlix Corporation
Inventor： Stephen Y. Chou , Wei Ding
IPC: G01N1/28 , B01L3/00 , G01N1/30 , G01N15/01 , G01N15/14 , G01N21/64 , G01N21/65 , G01N21/69 , G01N21/76 , G01N33/487 , G01N33/49 , G01N33/543 , G01N35/00
CPC classification number: G01N1/2813 , B01L3/5055 , G01N1/30 , G01N15/1484 , G01N21/6452 , G01N21/69 , G01N21/76 , G01N33/487 , G01N33/49 , G01N33/543 , G01N33/54366 , G01N35/00029 , G01N35/00871 , B01L2300/0809 , B01L2300/123 , B01L2400/0481 , G01N2015/012 , G01N2015/016 , G01N2015/018 , G01N2015/1486 , G01N2021/6482 , G01N21/658
Abstract: The present invention is related to the field of bio/chemical sampling, sensing, assays and applications. Particularly, the present invention is related to how to make the sampling/sensing/assay become simple to use, fast to results, highly sensitive, easy to use, using tiny sample volume (e.g. 0.5 uL or less), operated by a person without any professionals, reading by mobile-phone, or low cost, or a combination of them.
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公开(公告)号：US12007315B2
公开(公告)日：2024-06-11
申请号：US17060020
申请日：2020-09-30
Applicant: Essenlix Corporation
Inventor： Stephen Y. Chou , Wei Ding , Yufan Zhang , Ji Qi
IPC: G01N1/28
CPC classification number: G01N1/2813 , G01N1/286
Abstract: The present invention provides, among other things, devices, methods and applications of collecting, preserving, transporting, and analyzing tiny body fluids which have targeted biomarkers.
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公开(公告)号：US11846582B2
公开(公告)日：2023-12-19
申请号：US17858931
申请日：2022-07-06
Applicant: Essenlix Corporation
Inventor： Stephen Y. Chou , Wei Ding , Ji Qi , Jun Tian , Wu Chou
CPC classification number: G01N21/0303 , G01N1/2813 , G01N21/25 , G01N21/6458 , G01N33/49 , G01N2021/035 , G01N2021/6439 , G01N2201/0221
Abstract: Among other things, the present invention is related to devices and methods for improving optical analysis of a thin layer of a sample sandwiched between containing between two plates.
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公开(公告)号：US11712177B2
公开(公告)日：2023-08-01
申请号：US17016298
申请日：2020-09-09
Applicant: Essenlix Corporation
Inventor： Stephen Y. Chou , Wei Ding , Yufan Zhang , Ji Qi
IPC: A61B5/097 , A61B5/00 , G01N1/22 , G01N1/30 , G01N1/31 , G01N33/543 , G01N33/497 , G16H10/40 , G16H40/67 , A61B5/083 , B01L3/00 , G01N21/01 , G01N21/27 , G01N21/64 , G01N21/78 , G06Q40/08 , G01N21/17
CPC classification number: A61B5/097 , A61B5/0022 , A61B5/0833 , A61B5/0836 , B01L3/508 , G01N1/22 , G01N1/30 , G01N1/31 , G01N21/01 , G01N21/272 , G01N21/645 , G01N21/78 , G01N33/497 , G01N33/54306 , G01N33/54386 , G16H10/40 , G16H40/67 , B01L2300/0654 , B01L2300/0816 , B01L2300/0851 , B01L2300/123 , B01L2300/168 , B01L2400/0406 , G01N21/17 , G01N2001/2244 , G01N2001/302 , G01N2021/1776 , G01N2033/4975 , G06Q40/08
Abstract: Among other thing, the present invention provides solution to the problem, particularly, the present invention certain surfaces and certain sample holder to improve the sensitivity, speed, and easy-to-use of an optical signal based assays, such as colorimetric assays or fluorescence assays.
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