公开(公告)号：US09176206B2

公开(公告)日：2015-11-03

申请号：US12399603

申请日：2009-03-06

申请人： Hua Wang ,  Seyed Ali Hajimiri ,  Yan Chen

发明人： Hua Wang ,  Seyed Ali Hajimiri ,  Yan Chen

IPC分类号： G01N27/00 ,  G01N33/00 ,  G01R33/12

CPC分类号： G01R33/1269

摘要： The invention relates to an integrated measurement system to detect a quantity of magnetic particles in a sample. The measurement system includes a substrate. An electromagnetic (EM) structure disposed on the surface of the substrate is configured to receive a sample including the magnetic particles in proximity thereof. The integrated measurement system also includes an electrical current generator disposed on the surface of the substrate which is electro-magnetically coupled to the EM structure. The electrical current generator is configured to cause an electrical current to flow in the EM structure. The integrated measurement system also includes an effective inductance sensor disposed on the surface of the substrate which is configured to measure a selected one of an effective inductance and a change in effective inductance. The invention also relates to a method to determine the number of and/or the locations of the magnetic particles in a sample.

摘要翻译： 本发明涉及一种用于检测样品中的磁性颗粒的量的综合测量系统。 测量系统包括基板。 设置在基板的表面上的电磁（EM）结构被配置为接收包括邻近的磁性颗粒的样品。 集成测量系统还包括设置在基板的表面上的电流发生器，其电磁耦合到EM结构。 电流发生器被配置为使得电流在EM结构中流动。 集成测量系统还包括设置在衬底的表面上的有效电感传感器，其被配置为测量有效电感和有效电感的变化中选定的一个。 本发明还涉及确定样品中磁性颗粒数量和/或位置的方法。

公开(公告)号：US08969061B2

公开(公告)日：2015-03-03

申请号：US13522224

申请日：2011-01-20

申请人： Zhenyu Zhu ,  Yu Zheng ,  Shengxi Guan ,  Hua Wang ,  Aine Quimby ,  Penghua Zhang ,  Lynne Apone

发明人： Zhenyu Zhu ,  Yu Zheng ,  Shengxi Guan ,  Hua Wang ,  Aine Quimby ,  Penghua Zhang ,  Lynne Apone

IPC分类号： C12Q1/00 ,  C12Q1/68 ,  C12Q1/34 ,  C12N9/00 ,  C12N9/22

CPC分类号： C12N9/22 ,  C12Q1/6827 ,  C12Q2521/331

摘要： Compositions, methods and a kit are described relating to a novel family of enzymes which preferentially bind to a hydroxymethylated cytosine or a glucosylated hydroxymethylated cytosine and cleave double-stranded DNA at a defined distance 3′ of the recognition site to produce a cleavage fragment with a 1-3 base overhang.

摘要翻译： 描述了组合物，方法和试剂盒，其涉及一种新型家族的酶，其优先结合羟甲基化的胞嘧啶或葡糖基化的羟甲基化的胞嘧啶，并在识别位点的3'的限定距离处切割双链DNA以产生具有 1-3基础突出。

公开(公告)号：US08889191B2

公开(公告)日：2014-11-18

申请号：US12926936

申请日：2010-12-17

申请人： Likan Liang ,  Hua Wang ,  Padmanabh P. Bhatt ,  Michael L. Vieira

发明人： Likan Liang ,  Hua Wang ,  Padmanabh P. Bhatt ,  Michael L. Vieira

IPC分类号： A61K9/16 ,  A61K9/24 ,  A61K9/50 ,  A61K31/357 ,  A61K47/48 ,  B82Y5/00

CPC分类号： A61K9/5042 ,  A61K9/1652 ,  A61K9/1676 ,  A61K9/209 ,  A61K9/5047 ,  A61K9/5078 ,  A61K9/5084 ,  A61K31/357 ,  A61K31/7048 ,  A61K45/06 ,  A61K47/48969 ,  A61K47/6951 ,  B82Y5/00 ,  Y02A50/465

摘要： Pharmaceutical compositions of topiramate for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an optional immediate-release component, the compositions of which can be selectively adjusted, respectively, to release the active ingredient along a pre-determined release profile. Method of treating or preventing pathological disorders in mammalian subjects comprising the administration of the novel formulations disclosed herein is also provided.

公开(公告)号：US08880014B2

公开(公告)日：2014-11-04

申请号：US12844333

申请日：2010-07-27

申请人： David K. Homol ,  Hua Wang

发明人： David K. Homol ,  Hua Wang

IPC分类号： H01L27/088 ,  H04B1/04 ,  H03F3/68 ,  H03F1/02 ,  H03H11/30 ,  H03F3/72

CPC分类号： H03F3/72 ,  G05F1/468 ,  G05F1/565 ,  G05F1/575 ,  H01L27/0928 ,  H01L29/0611 ,  H02M3/1584 ,  H03F1/0261 ,  H03F1/34 ,  H03F1/56 ,  H03F3/19 ,  H03F3/195 ,  H03F3/211 ,  H03F3/217 ,  H03F3/245 ,  H03F2200/18 ,  H03F2200/411 ,  H03F2200/451 ,  H03F2203/21131 ,  H03F2203/21139 ,  H03F2203/7215 ,  H03G3/30 ,  H03G3/3042 ,  H03H11/30 ,  H03K17/6872 ,  H04B1/40 ,  Y10T307/406

摘要： Disclosed are CMOS-based devices for switching radio frequency (RF) signals and methods for biasing such devices. In certain RF devices such as mobile phones, providing different amplification modes can yield performance advantages. For example, a capability to transmit at low and high power modes typically results in an extended battery life, since the high power mode can be activated only when needed. Switching between such amplification modes can be facilitated by one or more switches formed in an integrated circuit and configured to route RF signal to different amplification paths. In certain embodiments, such RF switches can be formed as CMOS devices, and can be based on triple-well structures. In certain embodiments, an isolated well of such a triple-well structure can be provided with different bias voltages for on and off states of the switch to yield desired performance features during switching of amplification modes.

摘要翻译： 公开了用于切换射频（RF）信号的基于CMOS的装置和用于偏置这种装置的方法。 在诸如移动电话的某些RF设备中，提供不同的放大模式可以产生性能优点。 例如，在低功率和高功率模式下传输的能力通常会导致延长的电池寿命，因为只有在需要时才能激活高功率模式。 在集成电路中形成的一个或多个开关可以方便地在这种放大模式之间进行切换，并且将RF信号路由到不同的放大路径。 在某些实施例中，这样的RF开关可以形成为CMOS器件，并且可以基于三阱结构。 在某些实施例中，这种三阱结构的隔离阱可以具有用于开关的导通和截止状态的不同偏置电压，以在放大模式切换期间产生期望的性能特征。

公开(公告)号：US08878684B2

公开(公告)日：2014-11-04

申请号：US12959331

申请日：2010-12-02

申请人： Hua Wang ,  Seyed Ali Hajimiri

发明人： Hua Wang ,  Seyed Ali Hajimiri

IPC分类号： G08B21/00

CPC分类号： G01R29/26 ,  G01R31/31709 ,  G01R33/1269

摘要： A scalable and ultrasensitive frequency-shift magnetic array scheme. The theoretical limit of the sensor noise floor is shown to be dominated by the phase noise of the sensing oscillators. To increase the sensitivity, a noise suppression technique, Correlated Double Counting (CDC), is described with no power overhead. As an implementation example, a 64-cell sensor array is designed in a standard 65 nm CMOS process. The CDC scheme achieves an additional 6 dB noise suppression. The magnetic sensing capability of the presented sensor is verified by detecting micron size magnetic particles with an SNR of 14.6 dB for a single bead and an effective dynamic range of at least 74.5 dB. Applications in biosensing are contemplated, among other possible uses. Measurement of electrical properties is also contemplated.

摘要翻译： 可扩展和超灵敏的频移磁阵列方案。 传感器本底噪声的理论极限显示为感知振荡器的相位噪声。 为了提高灵敏度，在没有功率开销的情况下描述了噪声抑制技术相关双计数（CDC）。 作为实现示例，64标准的传感器阵列被设计在标准的65nm CMOS工艺中。 CDC方案实现了额外的6 dB噪声抑制。 通过检测单个珠的SNR为14.6 dB的微米尺寸磁性颗粒和至少74.5 dB的有效动态范围来验证所呈现的传感器的磁感测能力。 考虑到生物传感中的应用以及其它可能的用途。 还考虑了电性能的测量。

公开(公告)号：US08705486B2

公开(公告)日：2014-04-22

申请号：US13008971

申请日：2011-01-19

申请人： Shailesh Patil ,  Hua Wang ,  Xinzhou Wu ,  Junyi Li

发明人： Shailesh Patil ,  Hua Wang ,  Xinzhou Wu ,  Junyi Li

IPC分类号： H04Q3/08 ,  H04W72/04 ,  H04W72/02

CPC分类号： H04W72/0446 ,  H04W72/02 ,  H04W72/04 ,  H04W72/1205 ,  H04W76/14

摘要： A wireless terminal receives peer to peer resource control information from a base station. The peer to peer resource control information is used by the wireless terminal in a peer to peer network to control transmission scheduling and/or resource utilization. The base station sends the control signals at a first rate which is slower than the rate at which wireless terminals make transmission decisions for traffic slots. During the intervals between receipt of the base station control signals, wireless terminals make transmission decisions with regard to multiple traffic segments. The decisions are also influenced based on peer to peer signaling occurring between the wireless terminals in the network for each traffic slot. Resource utilization feedback information is provided from the wireless terminal to the base station. Based on the feedback information the base station updates the resource utilization control information and sends updated resource utilization control signals to the wireless terminals.

摘要翻译： 无线终端从基站接收对等资源控制信息。 对等资源控制信息由对等网络中的无线终端使用，以控制传输调度和/或资源利用。 基站以比无线终端对业务时隙进行传输决定的速率慢的第一速率发送控制信号。 在接收基站控制信号之间的间隔期间，无线终端就多个业务段做出传输决定。 基于针对每个业务时隙的网络中的无线终端之间发生的对等信令也会影响这些决定。 从无线终端向基站提供资源利用反馈信息。 基于反馈信息，基站更新资源利用控制信息，并向无线终端发送更新的资源利用控制信号。

公开(公告)号：US20140064163A1

公开(公告)日：2014-03-06

申请号：US13605822

申请日：2012-09-06

申请人： Georgios Tsirtsis ,  Junyi Li ,  Shailesh Patil ,  Saurabh R. Tavildar ,  Hua Wang

发明人： Georgios Tsirtsis ,  Junyi Li ,  Shailesh Patil ,  Saurabh R. Tavildar ,  Hua Wang

IPC分类号： H04W48/16 ,  H04W68/00 ,  H04W74/08 ,  H04W52/02

CPC分类号： H04W8/005 ,  H04W68/00

摘要： A method, an apparatus, and a computer program product for wireless communication are provided in connection with LTE based paging for peer discovery. In one example, an eNodeB is equipped to receive a message including a D2D discovery notification for a UE, determine that the UE is in an idle mode, and transmit a paging notification to the UE including the D2D discovery notification. In another example, a UE is equipped to receive, from an eNodeB, a paging notification including a D2D discovery notification, determine, while in idle mode, that the D2D discovery notification is successfully decoded, and transmit an ACK to the eNodeB using a RACH sequence on a PRACH.

摘要翻译： 结合基于LTE的寻呼提供用于无线通信的方法，装置和计算机程序产品，用于对等体发现。 在一个示例中，eNodeB被配备为接收包括UE的D2D发现通知的消息，确定UE处于空闲模式，并向UE发送包括D2D发现通知的寻呼通知。 在另一示例中，UE被配备为从eNodeB接收包括D2D发现通知的寻呼通知，在空闲模式下确定D2D发现通知被成功解码，并且使用RACH向eNodeB发送ACK 序列在PRACH上。

公开(公告)号：US08498100B1

公开(公告)日：2013-07-30

申请号：US13470633

申请日：2012-05-14

申请人： David Otto Whitt, III ,  Eric Joseph Wahl ,  David C. Vandervoort ,  Todd David Pleake ,  Rob Huala ,  Summer L. Schneider ,  Robyn Rebecca Reed McLaughlin ,  Matthew David Mickelson ,  Joel Lawrence Pelley ,  Timothy C. Shaw ,  Ralf Groene ,  Hua Wang ,  Christopher Harry Stoumbos ,  Karsten Aagaard

发明人： David Otto Whitt, III ,  Eric Joseph Wahl ,  David C. Vandervoort ,  Todd David Pleake ,  Rob Huala ,  Summer L. Schneider ,  Robyn Rebecca Reed McLaughlin ,  Matthew David Mickelson ,  Joel Lawrence Pelley ,  Timothy C. Shaw ,  Ralf Groene ,  Hua Wang ,  Christopher Harry Stoumbos ,  Karsten Aagaard

IPC分类号： G06F1/16

CPC分类号： G06F1/166 ,  E05D11/1064 ,  E05F5/08 ,  F16M11/38 ,  G05B11/01 ,  G06F1/1616 ,  G06F1/1618 ,  G06F1/1637 ,  G06F1/1654 ,  G06F1/1656 ,  G06F1/1662 ,  G06F1/1669 ,  G06F1/1681 ,  G06F1/1683 ,  G06F1/1684 ,  G06F1/1686 ,  G06F3/002 ,  G06F3/01 ,  G06F3/0202 ,  G06F3/0219 ,  G06F3/023 ,  G06F3/0414 ,  G06F3/0416 ,  G06F3/0487 ,  G06F3/0488 ,  G06F3/04886 ,  G06F9/541 ,  G06F11/3089 ,  G06F13/102 ,  H01H9/26 ,  H01H11/00 ,  H01H13/14 ,  H01H13/702 ,  H01H13/703 ,  H01H13/704 ,  H01H13/78 ,  H01H13/785 ,  H01H13/79 ,  H01H13/807 ,  H01H13/82 ,  H01H2201/036 ,  H01H2203/02 ,  H01H2203/036 ,  H01H2203/058 ,  H01H2205/006 ,  H01H2211/004 ,  H01H2211/006 ,  H01H2213/016 ,  H01H2217/004 ,  H01H2217/006 ,  H01H2217/01 ,  H01H2227/032 ,  H04M1/0216 ,  H04M1/0245 ,  H04M1/0254 ,  H04M1/72527 ,  H05K5/0226 ,  H05K5/0234 ,  Y02D10/14 ,  Y10T16/5401 ,  Y10T16/551 ,  Y10T29/49826

摘要： Flexible hinge and removable attachment techniques are described. In one or more implementations, a flexible hinge is configured to communicatively and physically couple an input device to a computing device and may implement functionality such as a support layer and minimum bend radius. The input device may also include functionality to promote a secure physical connection between the input device and the computing device. One example of this includes use of one or more protrusions that are configured to be removed from respective cavities of the computing device along a particular axis but mechanically bind along other axes. Other techniques include use of a laminate structure to form a connection portion of the input device.

公开(公告)号：US08455643B2

公开(公告)日：2013-06-04

申请号：US13001151

申请日：2009-09-07

申请人： Bingshe Xu ,  Hua Wang ,  Fangfang Wei ,  Huixia Xu ,  Xiaohong Fang ,  Yuying Hao ,  Liuqing Chen

发明人： Bingshe Xu ,  Hua Wang ,  Fangfang Wei ,  Huixia Xu ,  Xiaohong Fang ,  Yuying Hao ,  Liuqing Chen

IPC分类号： C07F3/06 ,  H01L51/50

CPC分类号： C07D401/06 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1029 ,  C09K2211/188 ,  H05B33/10 ,  Y02B20/181

摘要： A white-light organic electroluminescent material based on 8-hydroxyquinoline and the method for preparing the same, as well as an organic light emitting diode including this material. The material may be the compound represented by the Formula (IX) having a DCDC group, a 5-position substituted 8-hydroxyquinolinyl group and a carbazolyl group as red light-, green light- and blue-light emitting groups, respectively. It exhibits a spectrum having a band width of 182.4 nm that substantially covers the visible-light region, and has a color coordinate of (0.3177, 0.3946), which just locates within the white-light area. Such a material is capable of realizing a white-light emission, and may be used in a white-light OLED as a single light-emitting layer, which can decrease the number of layers of the white-light OLED and thereby improve the luminous efficiency, stabilize the light color, lower the turn-on voltage and simplify the fabrication process.

摘要翻译： 基于8-羟基喹啉的白光有机电致发光材料及其制备方法，以及包含该材料的有机发光二极管。 该材料可以分别是具有DCDC基团，5-位取代的8-羟基喹啉基和咔唑基的式（IX）表示的化合物作为红光，绿光和蓝光发射基团。 它具有基本上覆盖可见光区域的带宽为182.4nm的光谱，并且具有仅位于白光区域内的（0.3177,0.33946）的颜色坐标。 这样的材料能够实现白光发射，并且可以用作白光OLED作为单个发光层，这可以减少白光OLED的层数，从而提高发光效率 稳定光色，降低开启电压，简化制作工艺。

公开(公告)号：US20130065625A1

公开(公告)日：2013-03-14

申请号：US13228981

申请日：2011-09-09

申请人： Shailesh Patil ,  Hua Wang ,  Xinzhou Wu ,  Junyi Li ,  Thomas J. Richardson

发明人： Shailesh Patil ,  Hua Wang ,  Xinzhou Wu ,  Junyi Li ,  Thomas J. Richardson

IPC分类号： H04W72/04

CPC分类号： H04W68/00 ,  H04W8/005 ,  H04W84/18 ,  Y02D70/00 ,  Y02D70/142 ,  Y02D70/144 ,  Y02D70/162 ,  Y02D70/22

摘要： A method, a computer program product, and an apparatus are provided. The apparatus determines paging resources of a plurality of paging resources allocated for listening to paging messages. In addition, the apparatus transmits information indicating the allocated paging resources in a peer discovery signal. The apparatus may determine the paging resources on which to listen based on information received in peer discovery signals received from other wireless devices. The received information indicates the paging resources allocated to the other wireless devices.

摘要翻译： 提供了一种方法，计算机程序产品和装置。 该装置确定分配用于收听寻呼消息的多个寻呼资源的寻呼资源。 此外，该装置在对等体发现信号中发送指示分配的寻呼资源的信息。 该设备可以基于从其他无线设备接收的对等体发现信号中接收到的信息来确定要监听哪个寻呼资源。 所接收的信息指示分配给其他无线设备的寻呼资源。