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公开(公告)号：US20100280495A1
公开(公告)日：2010-11-04
申请号：US12578447
申请日：2009-10-13
申请人： David Paul , Benjamin Sutton , Brian McCollum , Brian D. Brandt , Emma Leung , Kenneth M. Martin , Amr Salahieh , Daniel Hildebrand
发明人： David Paul , Benjamin Sutton , Brian McCollum , Brian D. Brandt , Emma Leung , Kenneth M. Martin , Amr Salahieh , Daniel Hildebrand
IPC分类号： A61M25/00
CPC分类号： A61F2/2427 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2/90 , A61F2/95 , A61F2/954 , A61F2/962 , A61F2/966 , A61F2/97 , A61F2002/9517 , A61F2002/9528 , A61F2002/9534 , A61F2220/0041 , A61F2220/0075 , A61F2230/0067 , A61F2250/006
摘要： Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system.
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公开(公告)号：US08951299B2
公开(公告)日：2015-02-10
申请号：US12578447
申请日：2009-10-13
申请人： David Paul , Benjamin Sutton , Brian McCollum , Brian D. Brandt , Emma Leung , Kenneth M. Martin , Amr Salahieh , Daniel Hildebrand
发明人： David Paul , Benjamin Sutton , Brian McCollum , Brian D. Brandt , Emma Leung , Kenneth M. Martin , Amr Salahieh , Daniel Hildebrand
CPC分类号： A61F2/2427 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2/90 , A61F2/95 , A61F2/954 , A61F2/962 , A61F2/966 , A61F2/97 , A61F2002/9517 , A61F2002/9528 , A61F2002/9534 , A61F2220/0041 , A61F2220/0075 , A61F2230/0067 , A61F2250/006
摘要： Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system.
摘要翻译： 用于将医疗设备递送到受试者内的目标位置的医疗设备和递送系统。 在一些实施例中，医疗设备可以被锁定在完全展开和锁定的配置中。 在一些实施例中，输送系统配置有单个致动器以控制输送系统的多个部件的移动。 在一些实施例中，致动器控制输送系统的多个部件的独立和依赖的运动。
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公开(公告)号：US08840662B2
公开(公告)日：2014-09-23
申请号：US13282746
申请日：2011-10-27
申请人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider , Jeff Krolik
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/013 , A61F2/2415 , A61F2/2418 , A61F2/2427 , A61F2/2436 , A61F2220/0075 , A61F2230/0054 , A61F2230/0078 , A61F2250/0036 , A61F2250/0039
摘要： A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.
摘要翻译： 一种用于经皮置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以未膨胀构型经皮递送置换瓣膜和可扩张锚定至心脏瓣膜附近的步骤; 将锚扩展到展开构型，其中锚固件在第一锚固部位接触组织; 将锚重新定位到第二锚点; 并在第二锚点部署锚。
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公开(公告)号：US08805466B2
公开(公告)日：2014-08-12
申请号：US13106658
申请日：2011-05-12
申请人： Amr Salahieh , Jonah Lepak , Emma Leung , Brian D. Brandt , John P. Claude , Tom Saul
发明人： Amr Salahieh , Jonah Lepak , Emma Leung , Brian D. Brandt , John P. Claude , Tom Saul
CPC分类号： A61B1/05 , A61B1/06 , A61B5/01 , A61B5/0422 , A61B5/6853 , A61B5/6855 , A61B5/6858 , A61B18/1206 , A61B18/1492 , A61B18/1815 , A61B2017/003 , A61B2017/00867 , A61B2017/22038 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00083 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00232 , A61B2018/00238 , A61B2018/00267 , A61B2018/00285 , A61B2018/00291 , A61B2018/00357 , A61B2018/00375 , A61B2018/00613 , A61B2018/00642 , A61B2018/00702 , A61B2018/00744 , A61B2018/00791 , A61B2018/00797 , A61B2018/00839 , A61B2018/00898 , A61B2018/0212 , A61B2018/0262 , A61B2018/124 , A61B2018/1465 , A61B2090/065 , A61B2090/3966 , A61B2217/007 , A61B2562/125 , A61B2562/164 , A61M25/0108 , A61M25/0133 , A61M25/0147 , A61M25/04 , A61M25/10 , A61M25/1011 , A61M2025/0681 , A61N1/05 , A61N5/02 , C08L2201/12
摘要： A tissue electrode assembly includes a membrane configured to form an expandable, conformable body that is deployable in a patient. The assembly further includes a flexible circuit positioned on a surface of the membrane and comprising at least one base substrate layer, at least one insulating layer and at least one planar conducting layer. An electrically-conductive electrode covers at least a portion of the flexible circuit and a portion of the surface of the membrane not covered by the flexible circuit, wherein the electrically-conductive electrode is foldable upon itself with the membrane to a delivery conformation having a diameter suitable for minimally-invasive delivery of the assembly to the patient.
摘要翻译： 组织电极组件包括被配置成形成可展开在患者体内的可扩张的适形身体的膜。 组件还包括位于膜的表面上的柔性电路，并且包括至少一个基底衬底层，至少一个绝缘层和至少一个平面导电层。 导电电极覆盖柔性电路的至少一部分和未被柔性电路覆盖的膜的表面的一部分，其中导电电极可以自身与膜折叠成具有直径的输送构型 适合于将组件的微创传送给患者。
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公开(公告)号：US08231670B2
公开(公告)日：2012-07-31
申请号：US12264082
申请日：2008-11-03
申请人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider , Jeff Krolik
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/013 , A61F2/2415 , A61F2/2418 , A61F2/2427 , A61F2/2436 , A61F2220/0075 , A61F2230/0054 , A61F2230/0078 , A61F2250/0036 , A61F2250/0039
摘要： A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.
摘要翻译： 一种用于经皮置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以未膨胀构型经皮递送置换瓣膜和可扩张锚定至心脏瓣膜附近的步骤; 将锚扩展到展开构型，其中锚固件在第一锚固部位接触组织; 将锚重新定位到第二锚点; 并在第二锚点部署锚。
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公开(公告)号：US07959666B2
公开(公告)日：2011-06-14
申请号：US10982388
申请日：2004-11-05
申请人： Amr Salahieh , Jean-Pierre Dueri , Hans F. Valencia , Daniel Hildebrand , Brian D Brandt , Dwight P. Morejohn , Claudio Argento , Tom Saul , Ulrich R. Haug
发明人： Amr Salahieh , Jean-Pierre Dueri , Hans F. Valencia , Daniel Hildebrand , Brian D Brandt , Dwight P. Morejohn , Claudio Argento , Tom Saul , Ulrich R. Haug
CPC分类号： A61F2/2439 , A61F2/24 , A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/90 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2230/008 , A61F2250/006
摘要： The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.
摘要翻译： 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法，包括以未膨胀的构造将置换瓣膜和可扩张锚固体血管内输送到心脏瓣膜附近的步骤; 以及在所述锚上施加外部非液压膨胀或非气动扩张的致动力以改变所述锚的形状，例如通过使用可释放的展开工具向所述锚上施加近端和/或远端定向的力， 锚或锚的部分。 本发明的另一方面提供了一种包括置换阀的装置; 锚点 以及展开工具，其包括适于在锚上施加非液压膨胀或非气动膨胀的致动力的多个锚致动元件，以重构锚固件。
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公开(公告)号：US20080234814A1
公开(公告)日：2008-09-25
申请号：US12132304
申请日：2008-06-03
申请人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider , Jeff Krolik
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2427 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/006
摘要： Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.
摘要翻译： 用于血管内替换患者心脏瓣膜的装置，包括：直径为21法郎或更小的输送导管; 布置在输送导管内的可扩张锚; 以及设置在输送导管内的置换瓣膜。 本发明还包括用于血管内置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将具有不超过21个法兰的直径的导管插入患者体内; 通过导管将血管内递送更换瓣膜和可扩张锚固件到心脏瓣膜附近; 并部署锚杆和更换阀。
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公开(公告)号：US06709440B2
公开(公告)日：2004-03-23
申请号：US10192981
申请日：2002-07-11
IPC分类号： A61M2510
CPC分类号： A61F2/856 , A61F2/852 , A61F2/91 , A61F2/915 , A61F2/954 , A61F2/958 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2002/91591 , A61F2250/0039 , A61F2250/006
摘要： The present invention provides for an improved stent design and stent delivery catheter assembly for repairing a main vessel and a side branch vessel forming a bifurcation. The present invention includes a trap door stent design, a stent delivery catheter assembly, an apparatus for crimping the stent and the method for crimping the stent onto the catheter assembly, and the method for delivering and implanting the stent in a bifurcated vessel. More particularly, the invention relates to a stent having rings aligned along a common longitudinal axis and connected by links, where the stent has a proximal section, a distal section and a central section. The number of rings and the expanded diameter of the sections is varied to create a “trap door” capable of expanding to a slightly larger diameter than the proximal section and distal section of the stent. The stent is implanted at a bifurcation so that the proximal section and distal section are in the main vessel, and the central section covers at least a portion of the opening to the side branch vessel. A second stent can be implanted in the side branch vessel and abut the expanded central section to provide full coverage of the bifurcated area in the main vessel and the side branch vessel.
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公开(公告)号：US20200246527A1
公开(公告)日：2020-08-06
申请号：US16595280
申请日：2019-10-07
申请人： Daniel HILDEBRAND , Michael CALOMENI , Brian D. BRANDT , Janine ROBINSON , Ari RYAN , Daniel VARGHAI , Reza SHIRAZI , Mostafa GHOREYSHI , Amr SALAHIEH
发明人： Daniel HILDEBRAND , Michael CALOMENI , Brian D. BRANDT , Janine ROBINSON , Ari RYAN , Daniel VARGHAI , Reza SHIRAZI , Mostafa GHOREYSHI , Amr SALAHIEH
摘要： Intravascular blood pumps and methods of use. The blood pump include a pump portion that includes a collapsible blood conduit defining a blood flow lumen between an inflow and an outflow. The pump portion includes a distal collapsible impeller axially spaced from a proximal collapsible impeller, at least a portion of each of the distal and proximal collapsible impellers disposed between the inflow and the outflow.
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公开(公告)号：US20170042615A1
公开(公告)日：2017-02-16
申请号：US15339745
申请日：2016-10-31
申请人： Amr SALAHIEH , Jonah LEPAK , Emma LEPAK , Brian D. BRANDT , John P. CLAUDE , Tom SAUL
发明人： Amr SALAHIEH , Jonah LEPAK , Emma LEPAK , Brian D. BRANDT , John P. CLAUDE , Tom SAUL
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B1/00082 , A61B1/00179 , A61B1/05 , A61B1/06 , A61B1/0623 , A61B1/0684 , A61B5/01 , A61B5/0422 , A61B5/6843 , A61B5/6853 , A61B5/6855 , A61B5/6858 , A61B18/1206 , A61B18/1815 , A61B2017/003 , A61B2017/00867 , A61B2017/22038 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00083 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00232 , A61B2018/00238 , A61B2018/00267 , A61B2018/00285 , A61B2018/00291 , A61B2018/00351 , A61B2018/00357 , A61B2018/00363 , A61B2018/00375 , A61B2018/00577 , A61B2018/00613 , A61B2018/00642 , A61B2018/00702 , A61B2018/00744 , A61B2018/00791 , A61B2018/00797 , A61B2018/00839 , A61B2018/00898 , A61B2018/0212 , A61B2018/0262 , A61B2018/124 , A61B2018/1273 , A61B2018/1465 , A61B2018/1467 , A61B2090/065 , A61B2090/3966 , A61B2217/007 , A61B2218/002 , A61B2218/007 , A61B2562/125 , A61B2562/164 , A61M25/0108 , A61M25/0133 , A61M25/0147 , A61M25/04 , A61M25/10 , A61M25/1011 , A61M2025/0681 , A61N1/05 , A61N5/02 , C08L2201/12
摘要： Cardiac tissue ablation catheters including an inflatable and flexible toroidal or spherically shaped balloon disposed at a distal region of an elongate member, a flexible circuit carried by an outer surface of the balloon, the flexible circuit including, a plurality of flexible branches conforming to the radially outer surface of the balloon, each of the plurality of flexible branches including a substrate, a conductive trace carried by the substrate, and an ablation electrode carried by the substrate, the ablation electrode in electrical communication with the conductive trace, and an elongate shaft comprising a guidewire lumen extending in the elongate member and extending from a proximal region of the inflatable balloon to distal region of the inflatable balloon and being disposed within the inflatable balloon, wherein a distal region of the elongate shaft is secured directly or indirectly to the distal region of the inflatable balloon.
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