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74 条记录 (耗时 0.023 秒)

    Hydroxamic acid derivatives and medicinal utilization thereof
    31.
    发明授权
    Hydroxamic acid derivatives and medicinal utilization thereof 失效
    羟肟酸衍生物及其药用

    公开(公告)号：US06610729B1

    公开(公告)日：2003-08-26

    申请号：US09701043

    申请日：2000-11-22

    申请人： Tomokazu Gotou ,  Shinji Takeda ,  Kazuhiro Maeda ,  Tomohiro Yoshida ,  Naoki Sugiyama ,  Tadahiro Takemoto

    发明人： Tomokazu Gotou ,  Shinji Takeda ,  Kazuhiro Maeda ,  Tomohiro Yoshida ,  Naoki Sugiyama ,  Tadahiro Takemoto

    IPC分类号： C07C25906

    CPC分类号： C07D209/48 ,  C07C259/06 ,  C07D209/46 ,  C07D233/72 ,  C07D307/52 ,  C07D309/12 ,  C07D405/12 ,  C07D405/14

    摘要： The present invention relates to a hydroxamic acid derivative of the formula (I) wherein each symbol is as defined in the specification, a pharmacologically acceptable salt thereof, a pharmaceutical composition containing the derivative or a salt thereof, and to pharmaceutical use thereof. The hydroxamic acid derivative and a pharmacologically acceptable salt thereof of the present invention have an inhibitory activity of TNF &agr; production, and are useful for, for example, the prophylaxis and treatment of the diseases such as autoimmune diseases and inflammatory diseases (e.g., sepsis, MOF, rheumatoid arthritis, Crohn's disease, cachexia, myasthenia gravis, systemic lupus erythematosus, asthma, I type diabetes, psoriasis and the like), and the like.

    摘要翻译： 本发明涉及式（I）的异羟肟酸衍生物，其中各符号如说明书中所定义，其药理学上可接受的盐，含有其衍生物或其盐的药物组合物及其药学用途。 本发明的异羟肟酸衍生物及其药理学上可接受的盐具有TNFα产生的抑制活性，可用于例如自身免疫性疾病和炎症性疾病（例如败血症， MOF，类风湿关节炎，克罗恩病，恶病质，重症肌无力，系统性红斑狼疮，哮喘，I型糖尿病，牛皮癣等）等。

    Ball valve and methods of fabrication
    35.
    发明授权
    Ball valve and methods of fabrication 失效
    球阀及制造方法

    公开(公告)号：US4960262A

    公开(公告)日：1990-10-02

    申请号：US381918

    申请日：1989-07-18

    申请人： Mitsuharu Hashimoto ,  Shinji Takeda

    发明人： Mitsuharu Hashimoto ,  Shinji Takeda

    IPC分类号： F16K5/06 ,  F16K27/06

    CPC分类号： F16K27/067 ,  F16K5/0668 ,  Y10T137/0508 ,  Y10T137/6038

    摘要： A ball valve and a method for fabricating this ball valve wherein a ball seat, formed of a synthetic resin, is mounted at each end of a flow passage in a ball of the valve. A sealing end portion of the ball seat contacts the spherical surface of the ball only in the closed position of the ball. In the open position, the lip falls within a recess surrounding the end of the flow passage in the ball. A gap of 0.3 to 0.7 mm is formed, in the open position, between the wall surface of the recess and the end of the lip. The end of the lip should fall, in the open position of the ball, about 0.2 mm inside an imaginary continuation of the surface of the ball at the recess.

    COATING COMPOSITION FOR THICK COATING
    37.
    发明申请
    COATING COMPOSITION FOR THICK COATING 有权
    涂料组合物

    公开(公告)号：US20120094115A1

    公开(公告)日：2012-04-19

    申请号：US13266021

    申请日：2010-06-30

    申请人： Shinji Takeda ,  Masafumi Achiwa ,  Hiroyuki Noguchi ,  Akemi Kouketsu ,  Katsunobu Mochizuki

    发明人： Shinji Takeda ,  Masafumi Achiwa ,  Hiroyuki Noguchi ,  Akemi Kouketsu ,  Katsunobu Mochizuki

    IPC分类号： B32B3/00 ,  C09D5/14 ,  C08K3/22 ,  C08K3/30 ,  C08K3/34 ,  C09D133/20 ,  C08K3/26

    CPC分类号： C09D133/06 ,  C08F2220/185 ,  C08K7/22 ,  C09D7/61 ,  C09D7/70 ,  C09D133/10 ,  Y10T428/269 ,  C08F2220/1858 ,  C08F220/44 ,  C08F2220/302 ,  C08F220/06 ,  C08F212/08

    摘要： A coating composition has excellent application workability, facilitates thick coating, rarely causes cracks at an initial drying stage, and provides a dried film having excellent tensile properties and adhesiveness. The composition contains an aggregate and an emulsion with a polymer particle dispersed in an aqueous medium. The polymer particle includes 40% to 98% of a unit formed by polymerizing an alkyl(meth)acrylate monomer, the alkyl group having 4 to 14 carbon atoms, 0.1% to 5% of a unit formed by polymerizing an ethylenically unsaturated carboxylic acid monomer, 1% to 20% of a unit formed by polymerizing a vinyl monomer having a cyano group, 1% to 20% of a unit formed by polymerizing a reaction product of a (meth)acrylic acid and a monofunctional epoxy compound, and 0% to 50% of a unit formed by copolymerizing at least one of the above monomers with another monomer.

    摘要翻译： 涂料组合物具有优异的应用可加工性，便于厚涂层，在初始干燥阶段很少引起裂纹，并提供具有优异的拉伸性能和粘合性的干燥膜。 该组合物含有聚集体和分散在水性介质中的聚合物颗粒的乳液。 聚合物颗粒包含通过聚合（甲基）丙烯酸烷基酯单体，具有4至14个碳原子的烷基，通过聚合烯键式不饱和羧酸单体形成的单元的0.1％至5％形成的单元的40％至98％ ，通过使具有氰基的乙烯基单体聚合形成的单元的1〜20％，通过聚合（甲基）丙烯酸和单官能环氧化合物的反应产物而形成的单元的1〜20％，以及0％ 至50％的单体与至少一种上述单体共聚形成的单元。

    NONVOLATILE SEMICONDUCTOR MEMORY DEVICE
    39.
    发明申请
    NONVOLATILE SEMICONDUCTOR MEMORY DEVICE 有权
    非易失性半导体存储器件

    公开(公告)号：US20090201737A1

    公开(公告)日：2009-08-13

    申请号：US12368667

    申请日：2009-02-10

    申请人： Shinji Takeda ,  Yoshiharu Hirata

    发明人： Shinji Takeda ,  Yoshiharu Hirata

    IPC分类号： G11C16/04 ,  G11C7/00 ,  G11C16/06

    CPC分类号： G11C16/0483 ,  G11C16/10

    摘要： A semiconductor memory device comprises: a write circuit including a latch circuit configured by two inverters having a positive side power supply terminal supplied with a first voltage and a negative side power supply terminal supplied with a second voltage; and a write state machine controlling the first and second voltages. When writing data to a memory cell, the first voltage is changed to a second value that is lower than a first value. When writing data to a memory cell, the second voltage is changed to a third value that is lower than the second value. The write state machine lowers the second voltage to an intermediate value between the second value and the third value and, while maintaining this intermediate value, lowers the first voltage from the first value to the second value.

    摘要翻译： 一种半导体存储器件，包括：写入电路，包括由具有提供有第一电压的正侧电源端子和被提供有第二电压的负侧电源端子的两个反相器构成的锁存电路; 以及控制第一和第二电压的写状态机。 当将数据写入存储单元时，将第一电压改变为低于第一值的第二值。 当将数据写入存储单元时，第二电压被改变为低于第二值的第三值。 写状态机将第二电压降低到第二值和第三值之间的中间值，并且在保持该中间值的同时，将第一电压从第一值降低到第二值。

    Radio communication system, base station, relay station, mobile station, and packet transmission control method
    40.
    发明授权
    Radio communication system, base station, relay station, mobile station, and packet transmission control method 失效
    无线通信系统，基站，中继站，移动台，分组传输控制方式

    公开(公告)号：US07519029B2

    公开(公告)日：2009-04-14

    申请号：US10328025

    申请日：2002-12-26

    申请人： Shinji Takeda ,  Atsushi Fujiwara ,  Hitoshi Yoshino ,  Toru Otsu ,  Yasushi Yamao

    发明人： Shinji Takeda ,  Atsushi Fujiwara ,  Hitoshi Yoshino ,  Toru Otsu ,  Yasushi Yamao

    IPC分类号： H04B7/216 ,  H04B7/00

    CPC分类号： H04W52/247 ,  H04W24/10 ,  H04W28/18 ,  H04W48/08 ,  H04W52/286 ,  H04W52/46 ,  H04W68/00 ,  H04W88/04 ,  H04W92/10

    摘要： The object is to control interference in a permissible range by applying the CDMA system to signal collision in the conventional CSMA and TDMA base multihop systems and to relax the hidden terminal problem and others to enhance the throughput of the entire system by grouping of channel groups in multihop transmission and by control of transmission based on an interference level from another station. A multihop relay station calculates a desired signal level, for example, from an interference level at its own station of a packet sent from a mobile station, and notifies the mobile station of the desired signal level; and the mobile station calculates a transmission power amount of a packet from the desired signal level, determines whether the packet is transmissible to the station as a source of the desired signal level, and transmits the packet to the source station determined as a packet-transmissible station.

    摘要翻译： 目的是通过将CDMA系统应用于常规CSMA和TDMA基多跳系统中的信号冲突来控制在允许范围内的干扰，并且放松隐藏终端问题等，以通过将信道组分组来提高整个系统的吞吐量 基于来自另一台的干扰电平的多跳传输和传输控制。 多跳中继站例如从移动站发送的分组的本站的干扰级别计算期望的信号电平，并将移动台通知所需的信号电平; 并且移动台根据期望的信号电平计算分组的发送功率量，确定该分组是否作为期望的信号电平的来源发送到该电台，并将该分组发送到被确定为分组可传输的源站 站。