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公开(公告)号：US20090101549A1
公开(公告)日：2009-04-23
申请号：US12199068
申请日：2008-08-27
申请人： Dean Kamen , Jason A. Demers , Michael J. Wilt , Kevin L. Grant , Shannon Prescott , David E. Collins
发明人： Dean Kamen , Jason A. Demers , Michael J. Wilt , Kevin L. Grant , Shannon Prescott , David E. Collins
IPC分类号： B01D61/28
CPC分类号： A61M1/1656 , A61M1/0082 , A61M1/0084 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/16 , A61M1/1601 , A61M1/1633 , A61M1/1639 , A61M1/1668 , A61M1/1682 , A61M1/1686 , A61M1/1696 , A61M1/34 , A61M1/3403 , A61M1/3406 , A61M1/36 , A61M1/3607 , A61M1/3609 , A61M1/3627 , A61M39/1011 , A61M39/105 , A61M2205/12 , A61M2205/15 , A61M2205/3331 , A61M2205/3368 , A61M2205/3379 , A61M2205/502 , A61M2205/58 , A61M2209/08 , B01D61/30 , B01D61/32
摘要： A modular assembly for a portable hemodialysis system may include a dialysis unit, e.g., that contains suitable components for performing hemodialysis, such as a dialyzer, one or more pumps to circulate blood through the dialyzer, a source of dialysate, and one or more pumps to circulate the dialysate through the dialyzer, and a power unit having a housing that contains suitable components for providing operating power to the pumps of the dialysis unit. The power unit may be selectively connected to the dialysis unit and provide power (e.g., pneumatic power in the form of pressure and/or vacuum) to the dialysis unit for the pumps when connected to the dialysis unit, but may be incapable of providing power to the dialysis unit when disconnected from the dialysis unit. The dialysis unit and the power unit are sized and weighted to each be carried by hand by a human.
摘要翻译： 用于便携式血液透析系统的模块化组件可以包括透析单元，例如，其包含用于进行血液透析的合适组件，例如透析器，用于使血液循环通过透析器的一个或多个泵，透析液源和一个或多个泵 使透析液循环通过透析器，以及具有壳体的动力单元，该壳体包含用于向透析单元的泵提供操作功率的适当部件。 功率单元可以选择性地连接到透析单元并且当连接到透析单元时向泵的透析单元提供电力（例如，压力和/或真空的形式的气动功率），但是可能不能提供功率 与透析单元断开连接到透析单元。 透析单元和动力单元的尺寸和重量由人类手持。
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公开(公告)号：US20090095679A1
公开(公告)日：2009-04-16
申请号：US12199452
申请日：2008-08-27
CPC分类号： A61M1/1601 , A61M1/16 , A61M1/1613 , A61M1/1635 , A61M1/341 , A61M1/3434 , A61M1/3437 , A61M1/3441 , A61M1/3465 , A61M1/3609 , A61M1/3646 , A61M1/365 , A61M1/3652 , A61M2202/0413 , A61M2205/12 , A61M2205/18 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/502 , F04B45/0536 , G06F19/00 , G06F19/3481 , G16H40/63
摘要： Hemodialysis dialysis systems are disclosed. Hemodialysis systems of the invention may include a dialysate flow path including a balancing circuit, a mixing circuit, and/or a directing circuit. The circuits may be defined within one or more cassettes. The fluid circuits may be at least partially isolated, spatially and/or thermally, from electrical components of the system. A gas supply may be provided in fluid communication with the dialysate flow path and/or the dialyzer to urge dialysate through the dialyzer and blood back to the patient. The hemodialysis systems may include fluid handling devices, actuated using a control fluid, optionally delivered using a detachable pump. Fluid handling devices may be generally rigid and of a spheroid shape, optionally with a diaphragm dividing the device into compartments.
摘要翻译： 公开了血液透析透析系统。 本发明的血液透析系统可以包括透析液流路，其包括平衡电路，混合电路和/或定向电路。 电路可以被定义在一个或多个盒中。 流体回路可以与系统的电气部件至少部分隔离，空间和/或热。 可以提供气体供应，其与透析液流动路径和/或透析器流体连通，以促使通过透析器的透析液和血液返回给患者。 血液透析系统可以包括使用控制流体致动的流体处理装置，可选择地使用可拆卸的泵输送。 流体处理装置通常可以是刚性的并且具有球形形状，任选地具有将装置分隔成隔室的隔膜。
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公开(公告)号：US09724458B2
公开(公告)日：2017-08-08
申请号：US14122166
申请日：2012-05-24
申请人： Kevin L. Grant , Michael J. Wilt , Brian D. Tracey , Brett A. Rudolf , David E. Collins , Lisa A. Gustin , James D. Dale , Jesse T. Bodwell
发明人： Kevin L. Grant , Michael J. Wilt , Brian D. Tracey , Brett A. Rudolf , David E. Collins , Lisa A. Gustin , James D. Dale , Jesse T. Bodwell
CPC分类号： A61M1/3653 , A61M1/14 , A61M1/1658 , A61M1/168 , A61M1/1682 , A61M1/1686 , A61M1/3643 , A61M1/3644 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3656 , A61M1/367 , A61M1/3672 , A61M2205/12 , A61M2205/121 , A61M2205/128 , Y10T137/87169
摘要： A drain cassette for a dialysis unit has a fluid channel between venous and arterial connection ports, and a valve may controllably open and close fluid communication between a drain outlet port and the venous connection port or the arterial connection port. A blood circuit assembly and drain cassette may be removable from the dialysis unit, e.g., by hand and without the use of tools. A blood circuit assembly may include a single, unitary member that defines portions of a pair of blood pumps, control valves, channels to accurately position flexible tubing for an occluder, an air trap support, and/or other portions of the assembly. A blood circuit assembly engagement device may assist with retaining a blood circuit assembly on the dialysis unit, and/or with removal of the assembly. An actuator may operate a retainer element and an ejector element that interact with the assembly.
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公开(公告)号：US09649418B2
公开(公告)日：2017-05-16
申请号：US13352250
申请日：2012-01-17
IPC分类号： A61M1/16 , F04B43/073 , A61M1/10 , F17D3/00 , F04B43/06 , F04B9/109 , F04B13/02 , F04B43/00 , F04B7/02 , F04B43/02 , F04B45/02 , F04B49/22 , F04B53/06 , F04B53/10 , F04B53/16
CPC分类号： F04B53/10 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1087 , A61M1/1096 , A61M1/16 , A61M1/1605 , A61M1/1639 , A61M1/1656 , A61M1/1664 , A61M1/1666 , A61M1/287 , A61M2205/12 , A61M2205/128 , A61M2205/3317 , A61M2205/3324 , A61M2205/3368 , F04B7/02 , F04B9/109 , F04B13/02 , F04B23/06 , F04B41/06 , F04B43/00 , F04B43/02 , F04B43/06 , F04B43/073 , F04B43/0733 , F04B43/0736 , F04B45/02 , F04B45/0536 , F04B49/22 , F04B53/06 , F04B53/16 , F17D3/00 , Y10T137/0324 , Y10T137/0379 , Y10T137/2521 , Y10T137/85978 , Y10T137/86139
摘要： A pump cassette is disclosed. The pump cassette includes housing. The housing includes at least one fluid inlet line and at least one fluid outlet line. Also, the cassette includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps at least one fluid from the fluid inlet line to at least one of the fluid outlet line. Also, the cassette includes at least one mixing chamber within the housing. The mixing chamber is fluidly connected to the fluid outlet line.
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公开(公告)号：US08499780B2
公开(公告)日：2013-08-06
申请号：US13280274
申请日：2011-10-24
IPC分类号： G05D11/00
CPC分类号： F04B43/06 , A61M1/1006 , A61M1/1037 , A61M1/1062 , A61M1/16 , A61M1/1601 , A61M1/1639 , A61M2205/12 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3368 , F04B45/053 , Y10T137/0329 , Y10T137/2521 , Y10T137/2931 , Y10T137/7879 , Y10T137/85978 , Y10T137/86139
摘要： A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.
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公开(公告)号：US20130037480A1
公开(公告)日：2013-02-14
申请号：US13569793
申请日：2012-08-08
IPC分类号： B01D61/28
CPC分类号： A61M1/3672 , A61M1/16 , A61M1/1601 , A61M1/1621 , A61M1/1654 , A61M1/1694 , A61M1/267 , A61M1/3413 , A61M1/3424 , A61M1/3609 , A61M1/3621 , A61M1/3638 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M2205/12 , A61M2205/123 , A61M2205/128 , A61M2205/15 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/36 , A61M2205/505 , Y10T137/87893
摘要： Disclosed are hemodialysis and similar dialysis systems including fluid flow circuits. Hemodialysis systems may include a blood flow path, and a dialysate flow path including balancing, mixing, and/or a directing circuits. Preparation of dialysate may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit and/or the various fluid flow paths may be isolated from electrical components. A gas supply may be provided that, when activated, is able to urge dialysate through the dialyzer and blood back to the patient. Such a system may be useful during a power failure. The hemodialysis system may also include fluid handling devices, such as pumps, valves, mixers, etc., actuated using a control fluid. The control fluid may be delivered to the fluid handling devices using a detachable external pump. The fluid handling devices have a spheroid shape with a diaphragm dividing it into two compartments.
摘要翻译： 公开了血液透析和类似的透析系统，包括流体流动回路。 血液透析系统可以包括血液流路和包括平衡，混合和/或定向电路的透析液流动路径。 透析液的制备可能与患者透析分离。 电路可以被定义在一个或多个盒中。 流体回路和/或各种流体流动路径可以与电气部件隔离。 可以提供气体供应，当被激活时，能够通过透析器促使透析液和血液返回给患者。 这种系统在电源故障期间可能是有用的。 血液透析系统还可以包括使用控制流体致动的流体处理装置，例如泵，阀，混合器等。 可以使用可拆卸的外部泵将控制流体输送到流体处理装置。 流体处理装置具有球形形状，其中隔膜将其分成两个隔室。
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公开(公告)号：US20130022483A1
公开(公告)日：2013-01-24
申请号：US13619343
申请日：2012-09-14
IPC分类号： F04B43/02
CPC分类号： F04B43/06 , A61M1/1006 , A61M1/1037 , A61M1/1062 , A61M1/16 , A61M1/1601 , A61M1/1639 , A61M2205/12 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3368 , F04B45/053 , Y10T137/0329 , Y10T137/2521 , Y10T137/2931 , Y10T137/7879 , Y10T137/85978 , Y10T137/86139
摘要： A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.
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公开(公告)号：US20100051551A1
公开(公告)日：2010-03-04
申请号：US12199196
申请日：2008-08-27
申请人： Kevin L. Grant , Michael J. Wilt , Jason A. Demers
发明人： Kevin L. Grant , Michael J. Wilt , Jason A. Demers
CPC分类号： A61M1/1656 , A61M1/1668 , A61M2205/6045 , A61M2205/6081
摘要： A reagent supply arrangement for a hemodialysis system may include an E-prong connector having three parallel prongs with two outer prongs arranged in a common plane and a center prong arranged above the common plane, a first supply line for a first reagent connected in fluid communication with one of the outer prongs, a second supply line for a second reagent connected in fluid communication with the other of the outer prongs, a liquid line connected in fluid communication with the center prong, and a container for housing the first reagent having an inlet connected to the liquid line and an outlet connected to the first supply line for the first reagent. The E-prong connector may help prevent the improper connection to the dialysis unit, e.g., because the prong arrangement ensures connection in only one way to the dialysis unit.
摘要翻译： 用于血液透析系统的试剂供应装置可以包括具有三个平行插脚的E形插脚连接器，其中两个外部插脚布置在公共平面中，并且布置在公共平面上方的中心插脚，用于连接在流体连通中的第一试剂的第一供应管线 其中一个外部插脚，用于与另一个外部插脚流体连通的第二试剂的第二供应管线，与中心插脚流体连通的液体管线和用于容纳具有入口的第一试剂的容器 连接到液体管线和连接到用于第一试剂的第一供应管线的出口。 E-pin连接器可以有助于防止与透析单元的不正确连接，例如因为插脚布置确保仅以一种方式连接到透析单元。
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39.外观设计Blood pump cassette, air trap and front panel assembly for a portable hemodialysis system 有权用于便携式血液透析系统的血泵盒，空气阱和前面板组件公开(公告)号：USD606197S1
公开(公告)日：2009-12-15
申请号：US29323523
申请日：2008-08-27
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公开(公告)号：US20150174320A1
公开(公告)日：2015-06-25
申请号：US14323636
申请日：2014-07-03
申请人： Kevin L. Grant , Jason A. Demers , Brian D. Tracey , Dean Kamen , Richard J. Lanigan , Gregory R. Lanier, JR. , Bright C.K. Foo , Lisa A. Panneton , Thomas F. Soldau , Stephen L. Fichera , David D.B. Cannan
发明人： Kevin L. Grant , Jason A. Demers , Brian D. Tracey , Dean Kamen , Richard J. Lanigan , Gregory R. Lanier, JR. , Bright C.K. Foo , Lisa A. Panneton , Thomas F. Soldau , Stephen L. Fichera , David D.B. Cannan
CPC分类号： A61M5/162 , A61M5/14244 , A61M5/14248 , A61M39/1011 , A61M39/12 , A61M2005/1585 , A61M2005/1586 , A61M2039/1027 , A61M2205/60
摘要： A fluid connector assembly. The fluid connector assembly includes a tab portion including a slot; a plug portion slidably connected to the tab portion the plug portion comprising a fluid path and a disc, the disc configured to seat within the slot; a catch feature located on a first end of the tab portion and configured to interact with a reservoir; and a latching feature located on a second end of the tab portion, the latching feature configured to interact and lock onto the reservoir, wherein force applied to the plug portion may overcome a threshold force and unseat the disc from the slot wherein the plug portion moves with respect to the tab portion.
摘要翻译： 流体连接器组件。 流体连接器组件包括：包括槽的突片部分; 插头部分，其可滑动地连接到所述突片部分，所述插头部分包括流体路径和盘，所述盘被配置为位于所述槽内; 捕获特征位于所述突出部分的第一端并且被配置为与储存器相互作用; 以及锁定特征，其位于所述突出部分的第二端上，所述闩锁特征被配置成相互作用并锁定到所述储存器上，其中施加到所述插塞部分的力可以克服阈值力并使所述盘从所述插槽中移动，其中所述插头部分移动 相对于突片部分。
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