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    SYSTEMS AND METHODS FOR ANALYZING AN EXTRACTED SAMPLE USING AN IMMISCIBLE EXTRACTION SOLVENT
    35.
    发明申请
    SYSTEMS AND METHODS FOR ANALYZING AN EXTRACTED SAMPLE USING AN IMMISCIBLE EXTRACTION SOLVENT 审中-公开
    使用无溶剂萃取溶剂分析提取样品的系统和方法

    公开(公告)号：US20160351381A1

    公开(公告)日：2016-12-01

    申请号：US15113945

    申请日：2015-01-30

    Applicant: PURDUE RESEARCH FOUNDATION

    Inventor： Zheng Ouyang ,  Jiangjiang Liu ,  Yuen Ren ,  Morgan McLuckey

    IPC: H01J49/16 ,  C12Q1/46

    CPC classification number: H01J49/167 ,  B01D11/04 ,  C12Q1/46 ,  G01N2333/918 ,  H01J49/0431

    Abstract: The invention generally relates to systems and methods for analyzing an extracted sample using an immiscible extraction solvent. In certain embodiments, the invention provides a system for analyzing an analyte in a sample. The system includes an ionization probe and a mass spectrometer. The ionization probe includes a hollow body that optionally includes a distal tip. The hollow body is configured such that there is no substrate within the body and no electrode disposed on a surface of the body. An electrode is at least partially disposed within the hollow body.

    Abstract translation: 本发明一般涉及使用不混溶的提取溶剂分析提取的样品的系统和方法。 在某些实施方案中，本发明提供用于分析样品中的分析物的系统。 该系统包括电离探针和质谱仪。 电离探针包括可选地包括远端的中空体。 中空体被构造成使得在体内不存在基底，并且没有电极设置在身体的表面上。 电极至少部分地设置在中空体内。

    Ion generation using modified wetted porous materials
    36.
    发明授权
    Ion generation using modified wetted porous materials 有权
    使用改性润湿多孔材料的离子生成

    公开(公告)号：US09500630B2

    公开(公告)日：2016-11-22

    申请号：US14987154

    申请日：2016-01-04

    Applicant: Purdue Research Foundation

    Inventor： Robert Graham Cooks ,  Zheng Ouyang ,  He Wang

    IPC: H01J49/00 ,  G01N30/95 ,  H01J49/16 ,  H01J49/04 ,  G01N30/91 ,  G01N33/49

    CPC classification number: G01N30/95 ,  G01N30/91 ,  G01N33/49 ,  H01J49/0031 ,  H01J49/0404 ,  H01J49/0409 ,  H01J49/0431 ,  H01J49/167 ,  H01J49/168

    Abstract: The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate.

    Abstract translation: 本发明一般涉及使用改进的润湿多孔材料的离子产生。 在某些方面，本发明一般涉及使用基本上防止样品扩散到基底中的润湿多孔基质进行离子生成的系统和方法。 在其它方面，本发明一般涉及使用润湿多孔材料和干燥剂的离子产生。 在其它方面，本发明一般涉及使用改性润湿多孔基材的离子产生，其中多孔基材的至少一部分包括改变样品和基底之间的相互作用的材料。

    SYSTEMS AND METHODS FOR QUANTIFYING AN ANALYTE EXTRACTED FROM A SAMPLE
    38.
    发明申请
    SYSTEMS AND METHODS FOR QUANTIFYING AN ANALYTE EXTRACTED FROM A SAMPLE 审中-公开
    从样品中提取分析物的系统和方法

    公开(公告)号：US20160201051A1

    公开(公告)日：2016-07-14

    申请号：US15064865

    申请日：2016-03-09

    Applicant: Purdue Research Foundation

    Inventor： Zheng Ouyang ,  Yue Ren ,  Ziqing Lin

    IPC: C12N15/10 ,  H01J49/04 ,  H01J49/16 ,  C12Q1/68

    CPC classification number: H01J49/167 ,  C12Q1/6806 ,  Y10T436/24 ,  Y10T436/255

    Abstract: The invention generally relates to systems and methods for quantifying an analyte extracted from a sample. In certain embodiments, the invention provides methods that involve introducing a solvent into a capillary, introducing the capillary into a vessel including a sample such that a portion of the sample is introduced into the capillary, moving the sample and the solvent within the capillary to induce circulation within the sample and the solvent, thereby causing the analyte to be extracted from the sample and into the solvent, analyzing the analyte that has been extracted from the sample, and quantifying the analyte. In certain embodiments, the quantifying step is performed without knowledge of a volume of the sample and/or solvent.

    Abstract translation: 本发明一般涉及用于量化从样品中提取的分析物的系统和方法。 在某些实施方案中，本发明提供了将溶剂引入毛细管中的方法，将毛细管引入包含样品的容器中，使得将样品的一部分引入毛细管中，使样品和溶剂在毛细管内移动以诱导 在样品和溶剂中循环，从而使分析物从样品中提取并进入溶剂中，分析从样品中提取的分析物，并对分析物进行定量。 在某些实施方案中，在不知道样品和/或溶剂的体积的情况下进行定量步骤。

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