摘要:
The invention described herein relates to certain pyrimidinetrione N-substituted glycine derivatives of formula (I), (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.
摘要:
A microfabricated electron phase shift element is used for modifying the phase characteristics of an electron beam passing though its center aperture, while not affecting the more divergent portion of an incident beam to selectively provide a ninety-degree phase shift to the unscattered beam in the back focal plan of the objective lens, in order to realize Zernike-type, in-focus phase contrast in an electron microscope. One application of the element is to increase the contrast of an electron microscope for viewing weakly scattering samples while in focus. Typical weakly scattering samples include biological samples such as macromolecules, or perhaps cells. Preliminary experimental images demonstrate that these devices do apply a ninety degree phase shift as expected. Electrostatic calculations have been used to determine that fringing fields in the region of the scattered electron beams will cause a negligible phase shift as long as the ratio of electrode length to the transverse feature-size aperture is about 5:1. Calculations are underway to determine the feasibility of aspect smaller aspect ratios of about 3:1 and about 2:1.
摘要:
The present invention provides a mobile communication terminal comprising a wireless communication module and a host, wherein the wireless communication module further comprises a first interface connector and a module case; the host reserves positions for the insertion of the wireless communication module, and further comprises a second interface connector corresponding to the first interface connector positioned on the wireless communication module; the wireless communication module is connected to the host via the first interface connector and the second interface connector. The present invention also discloses a wireless communication module which is integrated with a SIM card unit. The present invention can reduce the waste in development and application, and shorten the development period of mobile communication terminals. Thus, the wireless communication module interface is simplified so that the wireless communication module interface is easy to use.
摘要:
Devices, systems, kits, and methods for detecting and/or identifying a plurality of spectrally labeled bodies well-suited for performing multiplexed assays. By spectrally labeling the beads with materials which generate identifiable spectra, a plurality of beads may be identified within the fluid. Reading of the beads is facilitated by restraining the beads in arrays, and/or using a focused laser.
摘要:
A system and method use magnetic field sensing to detect underground objects for strike avoidance. The system detects magnetic field components for both passive distortions in the magnetic field indicative of a ferromagnetic object and active magnetic fields that are impressed on an object by a signal generator. A detection module has a magnetic sensor assembly that detects the magnetic field components. The magnetic field component data is transferred through a multiplexer to an analog/digital converter to a processor. Pitch angle data from a pitch sensor and roll angle data from a roll sensor also may be transferred to the processor. The data is processed by the processor to determine the orientation of the detection module with respect to the object. The detection module may be installed in an underground boring tool or a trenching assembly.
摘要:
A method is provided for performing array microcrystallizations to determine suitable crystallization conditions for a molecule. The method comprises forming an array of microcrystallizations, each microcrystallization comprising a drop containing a molecule to be crystallized, the drop having a volume of less than 1 &mgr;L; storing the array of microcrystallizations under conditions suitable for molecule crystals to form in the drops in the array; and detecting molecule crystal formation in the drops.
摘要:
The invention addresses the problem that traditional Total Variation only enforces the horizontal and vertical intensity continuity and thus fails to reconstruct oblique edges well. In an embodiment, Directional Total Variation is defined which supports multiple gradient directions. It first pre-processes the image and determines the direction of edges/texture; Directional TV is calculated based on the gradients along the determined direction and its orthogonal direction. By utilizing adaptive weights to different directions in the regularization, Directional TV is capable of preserving edges independent from their orientation nicely. Thus, Directional TV regularization based image denoising, compression or super resolution tend to obtain better quality.