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公开(公告)号:US11406326B2
公开(公告)日:2022-08-09
申请号:US16489935
申请日:2018-03-13
申请人: Mordehy Haber , Simi Haber , Benny Pesach
发明人: Mordehy Haber , Simi Haber , Benny Pesach
摘要: A core body temperature monitoring apparatus placed superdermally over a user's skin, including a first temperature sensor, a second temperature sensor, a thermal insulation layer positioned intermediate the first and second temperature sensor and a heater for heating the apparatus and a subdermal tissue region underlying the user's skin. The subdermal tissue region is configured with variable thermal tissue parameters. A controller includes a switch configured for alternating between a calibration mode, wherein the heater is activated for calculating an instantaneous thermal tissue parameter, and a measurement mode, wherein the heater is inactive and the core body temperature is determined, based on the calculated instantaneous thermal tissue parameter.
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公开(公告)号:US08961458B2
公开(公告)日:2015-02-24
申请号:US13127823
申请日:2009-11-06
申请人: Benny Pesach , Gabriel Bitton , Ron Nagar , Ram Weiss
发明人: Benny Pesach , Gabriel Bitton , Ron Nagar , Ram Weiss
IPC分类号: A61F7/12 , A61M31/00 , A61F7/02 , A61M5/00 , A61M5/42 , A61B18/00 , A61B19/00 , A61F7/00 , A61M5/20
CPC分类号: A61M5/44 , A61B2018/00005 , A61B2090/0803 , A61F7/007 , A61F7/02 , A61F2007/0093 , A61F2007/0096 , A61F2007/0226 , A61M5/003 , A61M5/20 , A61M5/427 , A61M2205/273 , A61M2205/3368 , A61M2205/3653 , A61M2209/00
摘要: A therapeutic treatment device, system and method for improving administration of a temperature sensitive drug into a tissue on the body of a patient at a drug injection site are disclosed. The device includes a treatment element with a controllable heating element in temperature communicative contact with the tissue adjacent to the drug injection site. The controllable heating element is configured to heat the tissue adjacent to the drug injection site to a controllable temperature but does not heat the injected drug above a predetermined limiting temperature, above which degradation of the injected drug may occur.
摘要翻译: 公开了一种治疗装置,系统和方法,用于在药物注射部位改善对患者体内的组织中的感温药物的给药。 该装置包括具有可控加热元件的处理元件,其与邻近药物注射部位的组织温度交互接触。 可控制加热元件被配置为将邻近药物注射部位的组织加热到可控温度,但是不将注射的药物加热到预定的极限温度以上,在该极限温度以上可能发生注射药物的降解。
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公开(公告)号:US20100152644A1
公开(公告)日:2010-06-17
申请号:US12450246
申请日:2008-03-19
申请人: Benny Pesach , Gabriel Bitton , Ram Weiss , Ron Nagar
发明人: Benny Pesach , Gabriel Bitton , Ram Weiss , Ron Nagar
CPC分类号: A61M5/1723 , A61B18/14 , A61B18/1492 , A61B18/18 , A61F7/007 , A61F7/10 , A61H9/0057 , A61H23/00 , A61M5/14244 , A61M5/158 , A61M5/16831 , A61M37/0092 , A61M2005/1581 , A61M2005/1726 , A61M2205/05 , A61M2205/051 , A61M2205/052 , A61M2205/058 , A61N1/30 , A61N1/406 , A61N2/002 , A61N5/062 , A61N7/00 , A61N2005/0645 , G06F19/00
摘要: Systems, devices and methods for delivery of a chemical substance to the body of the patient are provided. Such embodiments may include an infusion catheter configured to be inserted into tissue, a catheter securing element configured to be adhered to the skin of the patient and further configured to secure the infusion catheter to the skin, a drug delivery pump configured to infuse a drug into the infusion catheter for delivery to a drug infused region on the body of the patient, and a treatment element configured to apply a treatment to the drug infused region to improve pharmacodynamics of the drug during a period of delivery of the drug to the patient.
摘要翻译: 提供了将化学物质递送到患者体内的系统,装置和方法。 这样的实施例可以包括构造成插入组织中的输注导管,导管固定元件,其构造成粘附到患者的皮肤上,并进一步被配置成将输注导管固定到皮肤上;药物输送泵,被配置为将药物注入 用于输送到患者身体上的药物输注区域的输注导管,以及配置成对药物输注区域施加治疗以改善药物递送到患者期间药物的药效学的治疗元件。
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公开(公告)号:US07608042B2
公开(公告)日:2009-10-27
申请号:US11048108
申请日:2005-02-01
申请人: Daniel Goldberger , Eric Shreve , Wayne Siebrecht , Benny Pesach , Gidon Pesach , Gabriel Bitton , Ron Nagar
发明人: Daniel Goldberger , Eric Shreve , Wayne Siebrecht , Benny Pesach , Gidon Pesach , Gabriel Bitton , Ron Nagar
CPC分类号: A61B5/14532 , A61B5/0215 , A61B5/14535 , A61B5/14546 , A61B5/15003 , A61B5/150221 , A61B5/150229 , A61B5/150305 , A61B5/150358 , A61B5/150366 , A61B5/150755 , A61B5/150992 , A61B5/155 , A61B5/157 , A61M5/14232 , A61M5/1723 , A61M2005/1726 , A61M2205/12 , A61M2230/201 , G06F19/00 , Y10T436/11 , Y10T436/117497
摘要: The present invention is directed towards apparatuses and methods for the automated measurement of blood analytes and blood parameters for bedside monitoring of patient blood chemistry. Particularly, the current invention discloses a programmable system that can automatically draw blood samples at a suitable programmable time frequency (or at predetermined timing), can automatically analyze the drawn blood samples and immediately measure and display blood parameters such as glucose levels, hematocrit levels, hemoglobin blood oxygen saturation, blood gases, lactate or any other blood parameter.
摘要翻译: 本发明涉及用于患者血液化学物质床边监测的血液分析物和血液参数的自动测量的装置和方法。 特别地,本发明公开了一种可以以合适的可编程时间频率(或在预定时间)自动抽取血液样本的可编程系统,可以自动分析所抽取的血液样本并立即测量和显示血液参数,例如葡萄糖水平,血细胞比容水平, 血红蛋白血氧饱和度,血气,乳酸或任何其他血液参数。
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公开(公告)号:US20080200838A1
公开(公告)日:2008-08-21
申请号:US11469586
申请日:2006-09-01
申请人: Daniel Goldberger , Eric Shreve , Wayne Siebrecht , Benny Pesach , Gidi Pesach , Gabby Bitton , Ron Nagar , Dalia Argaman , Stephen Bellomo , Robert Larson , Larry Johnson , Jill Klomhaus
发明人: Daniel Goldberger , Eric Shreve , Wayne Siebrecht , Benny Pesach , Gidi Pesach , Gabby Bitton , Ron Nagar , Dalia Argaman , Stephen Bellomo , Robert Larson , Larry Johnson , Jill Klomhaus
CPC分类号: A61B5/157 , A61B5/02438 , A61B5/14532 , A61B5/14546 , A61B5/150412 , A61B5/150503 , A61B5/150633 , A61B5/150702 , A61B5/150755 , A61B5/15087 , A61B5/15109 , A61B5/15117 , A61B5/15123 , A61B5/15153 , A61B5/15174 , A61B5/15176 , A61B5/155 , A61B5/6824 , A61B2560/0431
摘要: The present invention is a programmable, automated device for measurement and analysis of blood analytes and blood parameters. The device components are preferably combined in a single housing and either programmed to initiate automatic, periodic blood sampling or initiate automatic blood sampling via operator input or in response to a predefined event or in response to a signal from another instrument. The device operates automatically to draw blood samples and analyze the drawn blood samples to obtain the desired blood readings.
摘要翻译: 本发明是用于血液分析物和血液参数的测量和分析的可编程的自动化装置。 装置组件优选地组合在单个壳体中,并被编程为启动自动,定期血液取样或通过操作者输入或响应于预定事件或响应于来自另一仪器的信号来启动自动血液取样。 该装置自动操作以抽取血样并分析抽取的血样以获得所需的血液读数。
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公开(公告)号:US20070249916A1
公开(公告)日:2007-10-25
申请号:US10597108
申请日:2005-01-15
申请人: Benny Pesach , Ron Nagar , Gabriel Bitton , Avner Adoram
发明人: Benny Pesach , Ron Nagar , Gabriel Bitton , Avner Adoram
IPC分类号: A61B5/00
CPC分类号: A61B5/1455 , A61B5/0095 , A61B5/14532 , A61M5/1723 , A61M2230/201
摘要: Apparatus for assaying an analyte in blood in a patient's blood vessel comprising: a light provider comprising at least one light source that illuminates a tissue region in which a blood vessel is located with light that stimulates photoacoustic waves in the region; at least one acoustic transducer that generates signals responsive to the photoacoustic waves; a controller that receives the signals and processes them to determine which are responsive to photoacoustic waves that originate in the blood vessel and uses the determined signals to assay the analyte; wherein, the light provider and at least one transducer define a field of view that overlaps the blood vessel, said field of view having a central region and a lateral extent greater than about 4 mm.
摘要翻译: 用于测定患者血管中血液中分析物的装置,包括:光供应器,包括至少一个光源,所述至少一个光源照射在该区域中刺激光声波的光的血管位于其中的组织区域; 产生响应于所述光声波的信号的至少一个声换能器; 控制器,其接收信号并处理它们以确定响应于起源于血管的光声波并使用所确定的信号来测定分析物; 其中,所述光提供者和至少一个换能器限定与所述血管重叠的视野,所述视野具有大于约4mm的中心区域和横向范围。
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公开(公告)号:US20070179365A1
公开(公告)日:2007-08-02
申请号:US11345348
申请日:2006-01-31
申请人: Gabriel Bitton , Benny Pesach , Ron Nagar
发明人: Gabriel Bitton , Benny Pesach , Ron Nagar
CPC分类号: A61B5/0059 , A61B5/0095 , A61B5/441 , A61B5/4869 , A61B8/0858
摘要: A method of monitoring at least one fluid compartment of a body comprising: illuminating the skin with light that stimulates photoacoustic waves in the skin; and using the photoacoustic waves to measure change in the volume of the fluid compartment.
摘要翻译: 一种监测身体的至少一个流体隔室的方法,包括:用刺激皮肤中的光声波的光照射皮肤; 并使用光声波来测量流体隔室的体积变化。
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公开(公告)号:US20070129618A1
公开(公告)日:2007-06-07
申请号:US11157110
申请日:2005-06-20
申请人: Daniel Goldberger , Eric Shreve , Wayne Siebrecht , Benny Pesach , Gidi Pesach , Gabby Bitton , Ron Nagar
发明人: Daniel Goldberger , Eric Shreve , Wayne Siebrecht , Benny Pesach , Gidi Pesach , Gabby Bitton , Ron Nagar
CPC分类号: A61B5/155 , A61B5/14532 , A61B5/14546 , A61B5/15003 , A61B5/150221 , A61B5/150229 , A61B5/150305 , A61B5/150358 , A61B5/15087 , A61B5/150992 , A61B5/153 , A61B5/157 , A61B5/6866
摘要: A substantially automatic blood parameter testing apparatus for obtaining a blood sample and determining the concentration of at least one analyte is connected to a venous or arterial access line and further comprises a pump fixedly attached to a tube originating from the vascular access point; a valve fixedly attached to the tube and located above the pump mechanism; at least one measurement element; a needleless port; and an electronic meter. In addition, the automated blood parameter testing apparatus may be integrated into a complete system, further including a monitor and a central monitoring station.
摘要翻译: 用于获得血液样本并确定至少一种分析物的浓度的基本上自动的血液参数测试装置连接到静脉或动脉进入管线,并且还包括固定地连接到源自血管接入点的管的泵; 固定在管上并位于泵机构上方的阀; 至少一个测量元件; 无针孔 和电子表。 此外,自动血液参数测试装置可以集成到完整系统中,还包括监视器和中央监视站。
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公开(公告)号:US20070119710A1
公开(公告)日:2007-05-31
申请号:US11288033
申请日:2005-11-28
申请人: Daniel Goldberger , Eric Shreve , Wayne Siebrecht , Benny Pesach , Gidi Pesach , Gabby Bitton , Ron Nagar , Dalia Argaman , Stephen Bellomo , Robert Larson , Larry Johnson , Jill Klomhaus
发明人: Daniel Goldberger , Eric Shreve , Wayne Siebrecht , Benny Pesach , Gidi Pesach , Gabby Bitton , Ron Nagar , Dalia Argaman , Stephen Bellomo , Robert Larson , Larry Johnson , Jill Klomhaus
IPC分类号: G01N33/487
CPC分类号: G01N33/48764
摘要: The present invention is an integrated, test substrate handling apparatus for the measurement and analysis of blood analytes and blood parameters. The test substrate handling apparatus includes multiple test substrate components combined in a single unit. It advances a test substrate for measurement of blood parameters via programmed, periodic blood sampling or via operator input.
摘要翻译: 本发明是用于测量和分析血液分析物和血液参数的集成的测试基板处理装置。 测试基板处理装置包括以单个单元组合的多个测试基板部件。 它通过编程的,周期性的血液取样或通过操作员输入来推进用于测量血液参数的测试底物。
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公开(公告)号:US20070093698A1
公开(公告)日:2007-04-26
申请号:US11254550
申请日:2005-10-20
申请人: Dan Goldberger , Gabriel Bitton , Dalia Argaman , Ron Nagar , Benny Pesach
发明人: Dan Goldberger , Gabriel Bitton , Dalia Argaman , Ron Nagar , Benny Pesach
IPC分类号: A61B5/00
CPC分类号: A61B5/6833 , A61B5/0095 , A61B5/14532 , A61B5/1455 , A61B5/489 , A61B5/681 , A61B2562/08 , G01N21/1702
摘要: A sticker for attaching a photoacoustic sensor or portion thereof to the skin of a patient comprising: a substrate; an adhesive layer on the substrate suitable for adhering the sticker to the skin; apparatus for attaching the sticker to the photoacoustic sensor; and at least one device for presenting an identifying ID code.
摘要翻译: 用于将光声传感器或其一部分附接到患者皮肤的贴纸,包括:基底; 所述基底上的粘合剂层适于将所述贴纸粘附到皮肤上; 用于将贴纸附着到光声传感器的装置; 以及用于呈现识别ID码的至少一个设备。
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