公开(公告)号：US20160264995A1

公开(公告)日：2016-09-15

申请号：US15032544

申请日：2014-10-30

申请人： HIROSHIMA UNIVERSITY

发明人： Takashi Yamamoto ,  Kenichi Suzuki ,  Tetsushi Sakuma ,  Yuto Sakane

IPC分类号： C12N15/85

CPC分类号： C12N15/8509 ,  A01K2217/00 ,  A01K2227/50 ,  C12N15/102 ,  C12N15/90 ,  C12N2510/00

摘要： The present invention provides the following: a vector for inserting a desired nucleic acid into a predetermined site of a nucleic acid comprising a region formed of a first nucleotide sequence, the predetermined site, and a region composed of a second nucleotide sequence, in the stated order in the 5′-to-3′ direction, wherein the vector comprises a region formed of the first nucleotide sequence, the desired nucleic acid, and the second nucleotide sequence in the stated order in the 5′-to-3′ direction; a kit that includes this vector; a method of inserting a nucleic acid comprising a step for introducing this vector into a cell; a cell acquired by this method; and an organism comprising this cell.

摘要翻译： 本发明提供以下内容：用于将所需核酸插入包含由第一核苷酸序列，预定位点和由第二核苷酸序列组成的区域形成的区域的核酸的预定位点的载体， 在5'至3'方向的顺序，其中载体包含由第一核苷酸序列形成的区域，所需核酸和第二核苷酸序列按照5'至3'方向的所述顺序; 包含该载体的工具包; 一种插入核酸的方法，包括将该载体引入细胞的步骤; 通过该方法获得的细胞; 和包含该细胞的生物体。

公开(公告)号：US09381287B2

公开(公告)日：2016-07-05

申请号：US14383876

申请日：2013-01-29

申请人： Hiroshima University ,  Josho Gakuen Educational Foundation

发明人： Shinji Ninomiya ,  Taijiro Sueda ,  Tatsuya Kurosaki ,  Masaaki Kudo ,  Naoya Okamura

IPC分类号： A61M37/00 ,  A61M1/10 ,  A61M1/36

CPC分类号： A61M1/1086 ,  A61M1/1006 ,  A61M1/101 ,  A61M1/3639 ,  A61M1/3663 ,  A61M1/3666 ,  A61M1/3667 ,  A61M2205/3334 ,  A61M2205/3351 ,  A61M2205/3355 ,  A61M2205/3365

摘要： A blood supply flow rate controlling device (2), which is a device for controlling the blood supply flow rate in an extracorporeal circulation device connected to a living body (10), includes rotational frequency detecting means that detects the rotational frequency of the centrifugal pump (40) of the extracorporeal circulation device, inlet pressure detecting means and outlet pressure detecting means that detect the inlet pressure and the outlet pressure of the centrifugal pump (40), respectively, flow rate regulating means that regulates a flow rate of blood supplied to the living body by adjusting a flow path cross section area of the blood circulation circuit (20), and controlling means that controls the flow rate regulating means.

摘要翻译： 作为用于控制与生物体（10）连接的体外循环装置中的供血流量的装置的血液供给流量控制装置（2），包括旋转频率检测装置，其检测离心泵的旋转频率 （40），入口压力检测装置和出口压力检测装置，分别检测离心泵（40）的入口压力和出口压力，流量调节装置，其调节供给到 所述生物体通过调整所述血液循环回路（20）的流路截面积，以及控制手段来控制所述流量调节机构。

公开(公告)号：US20160075744A1

公开(公告)日：2016-03-17

申请号：US14785952

申请日：2014-04-22

申请人： KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION ,  HIROSHIMA UNIVERSITY

发明人： Takashi Yamamoto ,  Tetsushi Sakuma ,  Takahiro Nakamura ,  Yusuke Yagi ,  Yasuyuki Okawa

IPC分类号： C07K14/415 ,  C12N15/85 ,  C12N9/22

CPC分类号： C07K14/415 ,  C07K2319/80 ,  C12N9/22 ,  C12N15/8213 ,  C12N15/8216 ,  C12N15/8217 ,  C12N15/85 ,  C12Y301/21004

摘要： The object of the present invention is to, by analyzing PPR proteins that act to bind to DNA with a prediction that RNA recognition rules of PPR motifs can also be used for recognition of DNA, find a PPR protein showing such a characteristic. According to the present invention, it was revealed that, with a protein that can bind in a DNA base-selective manner or a DNA base sequence-specific manner, which contains one or more, preferably 2 to 30, more preferably 5 to 25, most preferably 9 to 15, of PPR motifs having a structure of the following formula 1 (wherein, in the formula 1, Helix A is a part that can form an α-helix structure; X does not exist, or is a part consisting of 1 to 9 amino acids; Helix B is a part that can form an α-helix structure; and L is a part consisting of 2 to 7 amino acids), and having a specific combination of amino acids corresponding to a DNA base or DNA base sequence as amino acids of three positions of No. 1 A.A., No. 4 A.A., in Helix A of the formula 1 and No. “ii” (-2) A.A. contained in L of the formula 1, the aforementioned object could be achieved. (Helix A)-X-(Helix B)-L  (Formula 1)

摘要翻译： 本发明的目的是通过分析PPR蛋白与DNA的结合，预测PPR基序的RNA识别规则也可以用于DNA的识别，找到显示出这种特征的PPR蛋白质。 根据本发明，揭示了含有1个以上，优选2〜30个，更优选5〜25个的DNA碱基选择性或DNA碱基序列特异性结合的蛋白质， 最优选9至15个具有下式1结构的PPR基序（其中，在式1中，螺旋A是可以形成α-螺旋结构的部分; X不存在，或者是由 1至9个氨基酸;螺旋B是可以形成α-螺旋结构的部分; L是由2至7个氨基酸组成的部分），并且具有对应于DNA碱基或DNA碱基的氨基酸的特异性组合 序列作为1号AA，4号AA的三个位置的氨基酸，在式1和No.“ii”（-2）AA的螺旋A中 包含在式1的L中，可以实现上述目的。 （螺旋A）-X-（螺旋B）-L（式1）

公开(公告)号：US09287577B2

公开(公告)日：2016-03-15

申请号：US14386907

申请日：2013-03-22

申请人： UNICHARM CORPORATION ,  Hiroshima University

发明人： Takayoshi Konishi ,  Toshio Hiraoka ,  Toshihide Kakizono

IPC分类号： H01M8/16 ,  B09B3/00 ,  H01M4/90 ,  H01M4/92 ,  H01M4/96 ,  H01M8/10

CPC分类号： H01M8/16 ,  B09B3/00 ,  H01M4/9041 ,  H01M4/9083 ,  H01M4/92 ,  H01M4/96 ,  H01M8/1004 ,  Y02E60/527

摘要： The biofuel cell has a positive electrode, a negative electrode, an external circuit electrically connecting the positive electrode and the negative electrode, a positive electrode region where the positive electrode is disposed, a negative electrode region where the negative electrode is disposed, and a proton permeable membrane disposed between the positive electrode region and the negative electrode region, and the negative electrode region houses a biocatalyst together with the crushed material. The negative electrode region is separated by a mesh into an electrode region and a crushed material region, the negative electrode is housed in the electrode region, and the crushed material is housed in the crushed material region.

摘要翻译： 生物燃料电池具有正极，负极，将正极和负极电连接的外部电路，设置有正极的正极区域，负极配置的负极区域和质子 设置在正极区域和负极区域之间的透湿膜，负极区域与破碎材料一起容纳生物催化剂。 将负极区域通过网格分离成电极区域和粉碎材料区域，将负极容纳在电极区域中，将破碎的材料容纳在粉碎材料区域中。

公开(公告)号：US09215495B2

公开(公告)日：2015-12-15

申请号：US13153002

申请日：2011-06-03

申请人： Mei Kodama

发明人： Mei Kodama

IPC分类号： H04N21/435 ,  H04N21/44 ,  H04N21/235 ,  H04N19/89 ,  H04N19/65 ,  H04N19/166

CPC分类号： H04N19/89 ,  H04N19/124 ,  H04N19/166 ,  H04N19/187 ,  H04N19/513 ,  H04N19/65 ,  H04N21/235 ,  H04N21/2353 ,  H04N21/2541 ,  H04N21/435 ,  H04N21/4355 ,  H04N21/44008 ,  H04N21/4627

摘要： A motion image distribution system includes a server and a user terminal. The server generates a feature quantity table CHT1 representing a data structure of motion image encoded data VDE, and authenticates the motion image encoded data VDE by using the generated feature quantity table CHT1. Then, the server transmits the motion image encoded data VDE and the feature quantity table CHT1 to the user terminal. The user terminal generates a feature quantity table CHT2 representing a data structure of the received motion image encoded data VDE, and authenticates received motion image encoded data VDE by using the generated feature quantity table CHT2. Then, the user terminal plays back the motion image encoded data VDE and outputs motion image playback information.

摘要翻译： 运动图像分发系统包括服务器和用户终端。 服务器生成表示运动图像编码数据VDE的数据结构的特征量表CHT1，并通过使用生成的特征量表CHT1来认证运动图像编码数据VDE。 然后，服务器将运动图像编码数据VDE和特征量表CHT1发送到用户终端。 用户终端生成表示接收到的运动图像编码数据VDE的数据结构的特征量表CHT2，并通过使用生成的特征量表CHT2认证接收到的运动图像编码数据VDE。 然后，用户终端重放运动图像编码数据VDE并输出运动图像重放信息。

公开(公告)号：US09181557B2

公开(公告)日：2015-11-10

申请号：US14123301

申请日：2012-06-01

申请人： Yutaka Nakashimada ,  Akihisa Kita ,  Tohru Suzuki ,  Shinsuke Sakai ,  Kazue Takaoka

发明人： Yutaka Nakashimada ,  Akihisa Kita ,  Tohru Suzuki ,  Shinsuke Sakai ,  Kazue Takaoka

IPC分类号： C12N1/21 ,  C12N15/74 ,  C12N9/88 ,  C12P7/06

CPC分类号： C12N15/74 ,  C12N9/88 ,  C12N2510/00 ,  C12N2510/02 ,  C12P7/065 ,  C12Y401/01023 ,  Y02E50/17

摘要： The present invention provides uracil-requiring Moorella bacteria obtained by destroying a gene coding for orotidine-5-phosphate decarboxylase; and transforming-gene-introduced Moorella bacteria obtained by introducing a gene coding for orotidine-5-phosphate decarboxylase and a transforming-gene to a chromosome of the uracil-requiring Moorella bacteria. The present invention was accomplished by uracil-requiring Moorella bacteria, comprising an MTA-D-pF strain that is obtained by destroying a gene coding for orotidine-5-phosphate decarboxylase on a chromosome of Moorella bacteria.

摘要翻译： 本发明提供了通过破坏编码乳清苷-5-磷酸脱羧酶的基因而获得的尿嘧啶需要的毛细菌; 以及通过将编码乳清苷-5-磷酸脱羧酶的基因和转化基因引入到需要尿嘧啶的Moorella细菌的染色体而获得的转化基因导入的Moorella细菌。 本发明通过需要尿嘧啶的Moorella细菌实现，其包含通过在Moorella细菌的染色体上破坏编码乳清苷-5-磷酸脱羧酶的基因获得的MTA-D-pF株。

公开(公告)号：US09018398B2

公开(公告)日：2015-04-28

申请号：US14379250

申请日：2012-12-12

申请人： National University of Corporation Hiroshima University

发明人： Kazuo Takimiya ,  Itaru Osaka

IPC分类号： C07D333/74 ,  C07F7/08 ,  C07F11/00 ,  C07F7/22

CPC分类号： C07F7/0812 ,  C07F7/0814 ,  C07F7/2208 ,  C07F11/00

摘要： An intermediate for an acenedichalcogenophene derivative is expressed by formula (1) or formula (2). In the formulae (1) and (2), Ar1 represents any one ring of a benzene ring, a naphthalene ring, or an anthracene ring having at least one of hydrogen thereof is substituted with a boronic acid group or a boronate ester group; Y represents an oxygen atom, a sulfur atom, or a selenium atom; and Z represents a substituent group. This intermediate for the acenedichalcogenophene derivative is capable of easily deprotecting the boronic acid group or the boronate ester group and allowing a substitution with a desired functional group, such that a desired synthesis of acenedichalcogenophene derivative, and further a desired synthesis of oligomers and polymers using this obtained acenedichalcogenophene derivative can be achieved.

摘要翻译： 加成苯并噻吩衍生物的中间体由式（1）或式（2）表示。 在式（1）和（2）中，Ar 1表示具有至少一个氢的苯环，萘环或蒽环的任何一个环被硼酸基或硼酸酯基取代; Y表示氧原子，硫原子或硒原子; Z表示取代基。 该烯烃衍生物衍生物的该中间体能够容易地使硼酸基团或硼酸酯基团脱保护并允许用所需官能团进行取代，使得所需的烯属化学发光苯并菲衍生物的合成，以及使用该方法进一步合成低聚物和聚合物 获得了可以达到的羟基苯并呋喃衍生物。

公开(公告)号：US08980658B2

公开(公告)日：2015-03-17

申请号：US13755846

申请日：2013-01-31

申请人： Shin Yokoyama

发明人： Shin Yokoyama

IPC分类号： H01L21/00

CPC分类号： H01L33/06 ,  B82Y10/00 ,  H01L29/127 ,  H01L33/26

摘要： A light-emitting element includes a n-type silicon oxide film and a p-type silicon nitride film. The n-type silicon oxide film and the p-type silicon nitride film formed on the n-type silicon oxide film form a p-n junction. The n-type silicon oxide film includes a plurality of quantum dots composed of n-type Si while the p-type silicon nitride film includes a plurality of quantum dots composed of p-type Si. Light emission occurs from the boundary between the n-type silicon oxide film and the p-type silicon nitride film by injecting electrons from the n-type silicon oxide film side and holes from the p-type silicon nitride film side.

摘要翻译： 发光元件包括n型氧化硅膜和p型氮化硅膜。 在n型氧化硅膜上形成的n型氧化硅膜和p型氮化硅膜形成p-n结。 n型氧化硅膜由n型Si构成的多个量子点构成，p型氮化硅膜由p型Si构成的多个量子点构成。 通过从n型氧化硅膜侧注入电子和从p型氮化硅膜侧的空穴，发生从n型氧化硅膜和p型氮化硅膜之间的边界发光。

公开(公告)号：US08976846B2

公开(公告)日：2015-03-10

申请号：US13635862

申请日：2011-03-17

申请人： Junzoh Shimizu ,  Minoru Fujishima ,  Masahiko Ohta ,  Toshio Takada

发明人： Junzoh Shimizu ,  Minoru Fujishima ,  Masahiko Ohta ,  Toshio Takada

IPC分类号： H04B1/38 ,  H04L27/04 ,  H04L5/06 ,  H04N21/4363

CPC分类号： H04L27/04 ,  G09G5/006 ,  G09G2370/045 ,  G09G2370/12 ,  G09G2370/16 ,  G09G2370/22 ,  H04L5/06 ,  H04N21/43637

摘要： A wireless transmission system includes a wireless HDMI transmitter and a wireless HDMI receiver. The wireless HDMI transmitter includes a carrier oscillator provided for each channel of an HDMI transmission path to output a carrier signal in a millimeter band, an OOK modulator provided for each carrier oscillator to perform on-off keying modulation on a carrier signal outputted by its corresponding carrier oscillator, and an input circuit provided for each channel of the HDMI transmission path to input a digital signal outputted by a source device to the OOK modulator. Radio signals have different planes of polarization from their adjacent channels.

摘要翻译： 无线传输系统包括无线HDMI发射机和无线HDMI接收机。 无线HDMI发射机包括为HDMI传输路径的每个信道提供的载波振荡器，以输出毫米波段中的载波信号，为每个载波振荡器提供的OOK调制器，以对由其相应的载波信号输出的载波信号执行开 - 关键控调制 载波振荡器和为HDMI传输路径的每个信道提供的输入电路，以将源装置输出的数字信号输入到OOK调制器。 无线电信号与其相邻信道具有不同的极化平面。

公开(公告)号：US08900953B2

公开(公告)日：2014-12-02

申请号：US13061221

申请日：2009-08-28

申请人： Seiichiro Higashi ,  Naohiro Koba

发明人： Seiichiro Higashi ,  Naohiro Koba

IPC分类号： H01L21/336 ,  H01L21/67 ,  H01L31/18 ,  H01L29/786 ,  C30B35/00 ,  H01L27/12 ,  C30B28/06 ,  C30B29/06 ,  C01B33/02 ,  H01L21/02

CPC分类号： H01L31/1892 ,  C01B33/02 ,  C30B28/06 ,  C30B29/06 ,  C30B35/00 ,  H01L21/02422 ,  H01L21/02532 ,  H01L21/02625 ,  H01L21/02667 ,  H01L21/6715 ,  H01L21/67248 ,  H01L27/1214 ,  H01L27/1218 ,  H01L27/1285 ,  H01L27/1292 ,  H01L29/78603 ,  H01L29/78636 ,  H01L31/1804 ,  Y02E10/547 ,  Y02P70/521

摘要： A crystal manufacturing apparatus capable of manufacturing a crystal in a desired position on a substrate is provided. A spring has one end fixed to a mount and the other end coupled to a magnetic body. The magnetic body has one end coupled to the spring and the other end coupled to a piston. A coil is wound around the magnetic body and electrically connected between a power supply circuit and a ground node (GND). The piston has a linear member inserted in a cylinder. The cylinder has a hollow columnar shape and a small hole at a bottom surface. The cylinder holds a silicon melt. A substrate is supported by an XY stage to be opposed to the small hole of the cylinder. The power supply circuit passes pulse shaped current through the coil to move the piston in an up-down direction (DR1). As a result, a droplet is discharged toward the substrate from the small hole at an initial speed of 1.02 m/s.

摘要翻译： 提供一种能够在基板上制造期望位置的晶体的晶体制造装置。 弹簧的一端固定到安装座，另一端连接到磁性体。 磁体具有与弹簧相连的一端，另一端与活塞相连。 线圈缠绕在磁体上并电连接在电源电路和接地节点（GND）之间。 活塞具有插入气缸中的线性构件。 圆柱体具有中空的柱状形状，在底面具有小孔。 气缸保持硅熔体。 基板由XY平台支撑以与圆筒的小孔相对。 电源电路使脉冲形电流通过线圈，使活塞沿上下方向（DR1）移动。 结果，以1.02m / s的初始速度从小孔向基板排出液滴。