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    HEMOSTATIC VALVE FOR HEART PUMP INTRODUCER
    47.
    发明申请
    HEMOSTATIC VALVE FOR HEART PUMP INTRODUCER 审中-公开

    公开(公告)号：US20170080199A1

    公开(公告)日：2017-03-23

    申请号：US15267323

    申请日：2016-09-16

    申请人： Abiomed, Inc.

    发明人： John Murphy

    IPC分类号： A61M39/06 ,  A61M1/12

    CPC分类号： A61M39/06 ,  A61M1/122 ,  A61M2039/062 ,  A61M2039/0633 ,  A61M2039/0686

    摘要： An introducer sheath for percutaneous insertion of a heart pump includes a tubular sheath body having a wall, a proximal end portion, a distal end portion, and an inner lumen. The introducer sheath includes a hemostatic valve disposed in the proximal end portion and forming a liquid tight seal across the inner lumen of the tubular sheath body. The hemostatic valve includes a valve cavity having a distal end and a proximal end, a first annular restriction formed within the valve cavity and having a first diameter, and a second annular restriction formed within the valve cavity distal to the first annular restriction and having a second diameter. The distal end of the valve cavity is spaced from the second annular restriction by a gap distance and a third diameter of the valve cavity along the gap distance is about equal to or greater than the first and second diameters.

    Hemostasis valve device for injecting a medical material into a patient, and related method
    49.
    发明授权
    Hemostasis valve device for injecting a medical material into a patient, and related method 有权
    用于向患者注射医疗材料的止血阀装置及相关方法

    公开(公告)号：US09566424B2

    公开(公告)日：2017-02-14

    申请号：US14127564

    申请日：2012-06-22

    申请人： Olivier Pessin

    发明人： Olivier Pessin

    IPC分类号： A61M39/06

    CPC分类号： A61M39/06 ,  A61M39/0606 ,  A61M39/0613

    摘要： The device according to the invention includes a hollow body delimiting an inner passage. It further includes an assembly for maintaining the material in position in the inner passage.The maintaining assembly includes a radially compressible member delimiting, when idle, a through passage aperture of the material, and a radial compression member compressing the compressible member, radially movable relative to an axis of the passage aperture to outwardly compress the compressible member.It includes a member for actuating the or each compression member, radially movable relative to the body to cause the compression member to go from a radially retracted position, in which the section of the passage aperture is maximal, to a position radially deployed in the compressible member, in which the section of the passage aperture is minimal.

    摘要翻译： 它包括用于致动或者每个压缩构件的构件，其可相对于主体径向移动，以使压缩构件从通道孔径的最大部分的径向缩回位置移动到径向展开在可压缩构件中的位置 构件，其中通道孔径的部分最小。

    Intrauterine fetal growth restriction—the biochemical rationale of treatment modalities including extraperitoneal transamniotic fetal supplements
    50.
    发明授权
    Intrauterine fetal growth restriction—the biochemical rationale of treatment modalities including extraperitoneal transamniotic fetal supplements 有权
    子宫内胎儿生长限制 - 治疗方式的生物化学原理，包括腹膜内经羊膜胎儿补充剂

    公开(公告)号：US09555052B2

    公开(公告)日：2017-01-31

    申请号：US13815468

    申请日：2013-03-05

    申请人： Sumathi Paturu

    发明人： Sumathi Paturu

    IPC分类号： A61K31/7004 ,  A61M25/00 ,  A61M39/06 ,  A61K31/51 ,  A61K9/00 ,  A61M39/02 ,  A61M5/172 ,  A61M39/04

    CPC分类号： A61K31/7004 ,  A61K9/0019 ,  A61K31/51 ,  A61M5/1723 ,  A61M25/00 ,  A61M25/0017 ,  A61M39/0208 ,  A61M39/04 ,  A61M39/06 ,  A61M2039/0205 ,  A61M2039/0223 ,  A61M2039/0235

    摘要： Intrauterine fetal growth restriction (IUGR) is an affliction of a disparaging spectrum, placental insufficiency being the major inciting pathology. The resultant fetal hypoglycemia is alleviated by intravenous hypertonic D-glucose 25-50% maternal supplements, by improving the Vmax of placental substrate transfer, as per Michaelis-Menten model. Fetal normoglycemia so restored in turn surprisingly improves fetal hypoxia, hypercapnia if any, lactic acidemia, acidosis, oliguria with/without oligohydromnios, hypertriglyceridemia, and the fetal nutrient, mineral and vitamin acquisition. The list being phenomenal can only convince an inquiring reader by a biochemical sojourn into the aquatic world of the fetus, herein described. Maternal carbohydrate predominant, essential amino acids/fatty acids rich IUGR-diet incorporating maximal amounts of vitamin and minerals are highly beneficial for attainable placental Vmax. Transamniotic isotonic D-glucose supplement via minimally invasive ‘Suprapubic extraperitonial pelvic approach’ for amniotomy (Sumathi Paturu's technique) with a Subcutaneously Implanted Pregnancy Port (SIPP) catheter is the additional therapy advocated.

    摘要翻译： 子宫内胎儿生长限制（IUGR）是一种瘫痪谱的折磨，胎盘功能不全是主要的煽动病理。 通过根据Michaelis-Menten模型，通过改善胎盘底物转移的Vmax，通过静脉高压D-葡萄糖25-50％的母体补充剂减轻所产生的胎儿低血糖。 如此恢复的胎儿正常血糖反过来令人惊讶地改善胎儿缺氧，高碳酸血症，如果有的话，乳酸性血症，酸中毒，伴有/不伴有低血红蛋白尿的少尿，高甘油三酯血症，以及胎儿营养，矿物质和维生素的摄入。 这个列表是惊人的，只能说服一个询问的读者通过生物化学栖息在胎儿的水生世界，这里描述。 孕妇碳水化合物占优势，必需氨基酸/富含脂肪酸的富含IUGR-饮食，掺入最大量的维生素和矿物质对于可达到的胎盘Vmax是非常有益的。 经皮下注射妊娠端口（SIPP）导管通过微创“耻骨上腹膜外盆腔方法”（Sumathi Paturu's技术）经皮下注射妊娠端口（SIPP）导管的经血清等渗D-葡萄糖补充剂是其他治疗方法。