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51.发明申请公开(公告)号：US20120261013A1
公开(公告)日：2012-10-18
申请号：US13527331
申请日：2012-06-19
CPC分类号： B01L3/502738 , B01L3/502761 , B01L3/502776 , B01L2200/0636 , B01L2200/0647 , B01L2300/0816 , B01L2300/0864 , B01L2300/089 , B01L2400/0415 , B01L2400/06 , B01L2400/0688 , B01L2400/082 , B07C5/34 , F16K99/0001 , F16K99/0017 , F16K99/0019 , F16K99/0034 , F16K99/0036 , F16K99/004 , F16K99/0046 , F16K99/0048 , F16K2099/0074 , F16K2099/008 , F16K2099/0084 , G01N2015/149 , Y10T29/49405 , Y10T137/0318 , Y10T137/0396 , Y10T137/0497 , Y10T137/2076 , Y10T137/2082 , Y10T137/2191 , Y10T137/2196 , Y10T137/2202 , Y10T137/2207 , Y10T137/2213 , Y10T137/2224 , Y10T436/143333 , Y10T436/25375
摘要： A microfluidic system includes a bubble valve for regulating fluid flow through a microchannel. The bubble valve includes a fluid meniscus interfacing the microchannel interior and an actuator for deflecting the membrane into the microchannel interior to regulate fluid flow. The actuator generates a gas bubble in a liquid in the microchannel when a sufficient pressure is generated on the membrane.
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公开(公告)号：US20120078145A1
公开(公告)日：2012-03-29
申请号：US12893683
申请日：2010-09-29
申请人： Arnaz S. Malhi , Manish Deshpande
发明人： Arnaz S. Malhi , Manish Deshpande
IPC分类号： A61H7/00
CPC分类号： A61H1/008 , A61F13/085 , A61H9/0092 , A61H2201/165 , A61H2201/5058 , A61H2201/5064 , A61H2201/5071 , A61H2201/5084 , A61H2205/06 , A61H2205/10 , A61H2230/625
摘要： A compression garment apparatus includes a compression garment and a pressurizer. The pressurizer intermittently pressurizes a therapeutic bladder on the compression garment and pressurizes a support bladder on the compression garment to enhance the fit of the compression garment and maintain the therapeutic bladder in position with respect to a target compression zone on a body part on which the garment is worn. The support bladder may be selectively pressurized when needed based at least in part on sensed physical characteristics.
摘要翻译： 压缩服装设备包括压缩衣服和加压器。 加压器间歇地对压缩衣服上的治疗膀胱加压并对压缩衣服上的支撑囊进行加压，以增强压缩服装的配合，并将治疗囊保持在相对于身体部位上的目标压缩区的适当位置， 被磨损 当需要时，至少部分地基于检测到的物理特性，可以选择性地加压支撑囊。
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公开(公告)号：US08096964B1
公开(公告)日：2012-01-17
申请号：US12893694
申请日：2010-09-29
IPC分类号： A61F5/00
CPC分类号： A61F13/085
摘要： A compression garment adapted for placement in a self-retaining configuration on a body part for imparting compression therapy on the body part. The compression garment includes a flexible wrap and a bladder held in use by the wrap for compressing the body part. The wrap includes and inner flap and an outer flap. The outer flap overlaps the inner flap when the garment is in a self-retaining configuration on the body part. A fastener secures the wrap in the self-retaining configuration. When the outer flap overlaps the inner flap, at least a portion of the inner flap is exposed forming a grip for grasping the inner flap when tightening and fastening the garment in the self-retaining configuration.
摘要翻译： 一种压缩衣服，其适于放置在身体部位上的自保持构造中，用于对身体部位进行压缩治疗。 压缩衣服包括柔性包装和保持在使用中的用于压缩身体部分的包裹物的囊。 包裹物和内皮瓣和外皮瓣。 当衣服处于身体部位上的自保持构造时，外翼片与内折板重叠。 紧固件将包裹件固定在自保持配置中。 当外翼片与内翼片重叠时，当紧固并固定衣服处于自保持构造时，内翼片的至少一部分露出，形成用于抓握内翼片的把手。
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公开(公告)号：US20110201981A1
公开(公告)日：2011-08-18
申请号：US12705290
申请日：2010-02-12
申请人： Manish Deshpande , Ross Kanter
发明人： Manish Deshpande , Ross Kanter
IPC分类号： A61H7/00
CPC分类号： A61H23/04 , A61H9/0078 , A61H2201/165 , A61H2201/50 , A61H2205/106
摘要： A compression garment assembly comprises a compression garment adapted for placement on a body part in a self-retaining configuration and for removal from the body part. The compression garment has at least one inflatable bladder for applying compression to the body part. A portable controller unit is adapted for fluid connection to the inflatable bladder and is configured for cyclically inflating the bladder. The compression garment and portable controller unit are configured so that the portable controller unit must be disconnected from the compression garment before the compression garment can be removed from the body part. Loss of the portable controller unit by, for example, accidental disposal with the compression garment is thus prevented.
摘要翻译： 压缩衣服组件包括压缩衣服，其适于放置在自身保持构造的身体部分上并且用于从身体部分移除。 压缩衣服具有至少一个用于对身体部位施加压力的可充气囊。 便携式控制器单元适于流体连接到可膨胀气囊，并且被配置用于循环地使气囊膨胀。 压缩衣物和便携式控制器单元构造成使得便携式控制器单元必须在压缩衣服可以从身体部位移除之前与压缩衣服断开连接。 因此防止例如通过压缩服装意外处理便携式控制器单元的损失。
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55.发明授权公开(公告)号：US07514000B2
公开(公告)日：2009-04-07
申请号：US11479125
申请日：2006-06-30
CPC分类号： B01D63/087 , B01D63/088 , B01D67/0034 , B01D67/0062 , B01D2313/13 , B01D2313/40 , B01D2325/028 , B01D2325/12 , B01L3/06 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502753 , B01L2200/027 , B01L2200/028 , B01L2200/146 , B01L2300/041 , B01L2300/047 , B01L2300/0681 , B01L2300/0816 , B01L2300/0874 , B01L2400/0421 , B01L2400/0481 , B01L2400/0655 , B01L2400/0666 , C02F2209/36 , C30B7/00 , C30B29/58 , G01N27/44743 , G01N27/44773 , Y10S977/786 , Y10T156/10
摘要： A system and method for integrating microfluidic components in a microfluidic system enables the microfluidic system to perform a selected microfluidic function. A capping module includes a microfluidic element for performing a microfluidic function. The capping module is stacked on a microfluidic substrate having microfluidic plumbing to incorporate the microfluidic function into the system. The microfluidic element may comprise a matrix having an affinity for selected molecules in a sample. The matrix binds, reacts with and/or retains the selected molecules without affecting other molecules in the sample.
摘要翻译： 用于在微流体系统中整合微流体组分的系统和方法使得微流体系统能够执行选定的微流体功能。 封盖模块包括用于执行微流控功能的微流体元件。 封盖模块堆叠在具有微流管道的微流体衬底上，以将微流控功能结合到系统中。 微流体元件可以包含对样品中选定分子具有亲和性的基质。 该基质与所选择的分子结合，反应和/或保留，而不影响样品中的其它分子。
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公开(公告)号：US07455770B2
公开(公告)日：2008-11-25
申请号：US10951473
申请日：2004-09-27
申请人： John R. Gilbert , Manish Deshpande
发明人： John R. Gilbert , Manish Deshpande
CPC分类号： C30B7/00 , B01L3/06 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502753 , B01L2200/027 , B01L2200/028 , B01L2200/146 , B01L2300/041 , B01L2300/047 , B01L2300/0681 , B01L2400/0481 , B01L2400/0655 , B01L2400/0666 , C30B29/58 , F04B43/02 , F04B43/043 , Y10T137/0324 , Y10T436/2575
摘要： A system and method for integrating microfluidic components in a microfluidic system enables the microfluidic system to perform a selected microfluidic function. A capping module includes a microfluidic element for performing a microfluidic function. The capping module is stacked on a microfluidic substrate having microfluidic plumbing to incorporate the microfluidic function into the system. An infusion pump for delivering a fluid from a fluid source may be integrated in a microfluidic chip using a capping module having pumping components formed therein.
摘要翻译： 用于在微流体系统中整合微流体组分的系统和方法使得微流体系统能够执行选定的微流体功能。 封盖模块包括用于执行微流控功能的微流体元件。 封盖模块堆叠在具有微流管道的微流体衬底上，以将微流控功能结合到系统中。 用于从流体源输送流体的输液泵可以使用其中形成有泵送部件的封盖模块集成在微流体芯片中。
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公开(公告)号：US07298478B2
公开(公告)日：2007-11-20
申请号：US10915016
申请日：2004-08-09
IPC分类号： G01N21/00
CPC分类号： G01N15/1434 , G01N15/1459 , G01N15/1484 , G01N21/6452 , G01N2015/1081
摘要： An optical system for acquiring fast spectra from spatially channel arrays includes a light source for producing a light beam that passes through the microfluidic chip or the channel to be monitored, one or more lenses or optical fibers for capturing the light from the light source after interaction with the particles or chemicals in the microfluidic channels, and one or more detectors. The detectors, which may include light amplifying elements, detect each light signal and transducer the light signal into an electronic signal. The electronic signals, each representing the intensity of an optical signal, pass from each detector to an electronic data acquisition system for analysis. The light amplifying element or elements may comprise an array of phototubes, a multianode phototube, or a multichannel plate based image intensifier coupled to an array of photodiode detectors.
摘要翻译： 用于从空间通道阵列获取快速光谱的光学系统包括用于产生穿过微流体芯片或待监测通道的光束的光源，用于在相互作用之后捕获来自光源的光的一个或多个透镜或光纤 微流体通道中的颗粒或化学物质，以及一个或多个检测器。 可以包括光放大元件的检测器检测每个光信号并将光信号转换成电子信号。 每个表示光信号强度的电子信号从每个检测器传递到电子数据采集系统进行分析。 光放大元件可以包括耦合到光电二极管检测器阵列的光管阵列，多子光电管或基于多通道板的图像增强器。
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公开(公告)号：US07134639B2
公开(公告)日：2006-11-14
申请号：US11099014
申请日：2005-04-04
IPC分类号： F16K31/02
CPC分类号： F16K99/0001 , F15C5/00 , F16K99/0005 , F16K99/0007 , F16K99/0009 , F16K99/0015 , F16K99/0046 , F16K99/0048 , F16K2099/0069 , F16K2099/0071 , F16K2099/0074 , F16K2099/0076 , F16K2099/008 , F16K2099/0084 , G05D7/0694 , Y10T29/49412 , Y10T137/87314
摘要： A latching microregulator for regulating liquid flow on micro-scale levels comprises a substrate having an inlet port and an outlet port, a valve element defining a valve chamber for opening and closing the inlet port, and an actuator assembly for actuating the valve element. The valve chamber is configured to contain a volume of fluid, and the inlet port and the outlet port are in fluid communication with the valve chamber to provide a liquid flow path through the chamber. The actuator assembly comprises a cantilever beam for moving the valve element between an open position and a closed position, an actuator, such as a piezoelectric element, for moving the cantilever beam, and a latch, such as a permanent magnet, for securing the cantilever beam in the closed position. A flow regulation system comprises a plurality of fluid channels of varied flow conductance and a plurality of latching microregulators for selectively blocking or allowing flow through each of the fluid channels.
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公开(公告)号：US07033148B2
公开(公告)日：2006-04-25
申请号：US10329013
申请日：2002-12-23
IPC分类号： F04B17/00
CPC分类号： F04B43/025 , F04B43/04 , F04B43/043 , Y10S977/963
摘要： An electromagnetic micropump for pumping small volumes of liquids and gases comprises a magnetic actuator assembly, a flexible membrane and a housing defining a chamber and a plurality of valves. The magnetic actuator assembly comprises a coil and a permanent magnet for deflecting the membrane to effect pumping of the fluid. A plurality of micropumps may be stacked together to increase pumping capacity.
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60.发明授权Microfluidic system including a bubble valve for regulating fluid flow through a microchannel 有权微流体系统包括用于调节流过微通道的流体的气泡阀公开(公告)号：US06877528B2
公开(公告)日：2005-04-12
申请号：US10179586
申请日：2002-06-24
CPC分类号： B01L3/502738 , B01L3/502761 , B01L3/502776 , B01L2200/0636 , B01L2200/0647 , B01L2300/0816 , B01L2300/0864 , B01L2300/089 , B01L2400/0415 , B01L2400/06 , B01L2400/0688 , B01L2400/082 , B07C5/34 , F16K99/0001 , F16K99/0017 , F16K99/0019 , F16K99/0034 , F16K99/0036 , F16K99/004 , F16K99/0046 , F16K99/0048 , F16K2099/0074 , F16K2099/008 , F16K2099/0084 , G01N2015/149 , Y10T29/49405 , Y10T137/0318 , Y10T137/0396 , Y10T137/0497 , Y10T137/2076 , Y10T137/2082 , Y10T137/2191 , Y10T137/2196 , Y10T137/2202 , Y10T137/2207 , Y10T137/2213 , Y10T137/2224 , Y10T436/143333 , Y10T436/25375
摘要： A microfluidic system includes a bubble valve for regulating fluid flow through a microchannel. The bubble valve includes a fluid meniscus interfacing the microchannel interior and an actuator for deflecting the membrane into the microchannel interior to regulate fluid flow. The actuator generates a gas bubble in a liquid in the microchannel when a sufficient pressure is generated on the membrane.
摘要翻译： 微流体系统包括用于调节通过微通道的流体流动的气泡阀。 气泡阀包括与微通道内部接合的流体弯液面和用于将膜偏转到微通道内部以调节流体流动的致动器。 当在膜上产生足够的压力时，致动器在微通道中的液体中产生气泡。
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