Method and apparatus for controlling the washing step in a blood centrifugation cell

    公开(公告)号:US06716151B2

    公开(公告)日:2004-04-06

    申请号:US10125995

    申请日:2002-04-19

    IPC分类号: B04B1300

    摘要: A method and apparatus for controlling the washing step in a blood centrifugation cell in which washing solution is introduced into the blood centrifugation cell and the cell contains compacted red cells and supernatant at the beginning of the washing step. The apparatus can comprise various sensors and a computer. The sensors sense and transmit to the computer three inputs. The first input is indicative of the total volume of blood that enters the cell during the filling step and the total amount of washing solution that enters the cell during the washing step. The second input is indicative of the hematocrit value of the blood introduced during the filling step. The third input is indicative of the geometric characteristics of the cell. Based on the inputs, the computer executes an algorithm that produces a first output that is the concentration of the supernatant in the supernatant-washing solution mixture.

    Method of autologous blood recovery
    54.
    发明申请
    Method of autologous blood recovery 有权
    自体血液回收方法

    公开(公告)号:US20020147440A1

    公开(公告)日:2002-10-10

    申请号:US10159553

    申请日:2002-05-31

    发明人: Keith A. Samolyk

    摘要: The invention is directed to a blood bag system, comprising a closed, sterile bag of substantially transparent, bio-compatible material, defining upper and lower ends; an infusion port at the upper end of the bag; an outlet port at the lower end of the bag; an inlet port at the lower end of the bag; a hemo-concentrator having an inlet port and an outlet port; a pair of inlet tubes fluidly connected to the hemo-concentrator inlet port; and a pair of outlet tubes fluidly connected to the hemo-concentrator outlet port. One of the inlet tubes is fluidly connected to the outlet port of the bag, and one of the outlet tubes fluidly connected to the inlet port of the bag. The other of the inlet tubes and the other of the outlet tubes are temporarily sealed (e.g., clamped) to prevent flow therethrough. The bag, the one outlet tube, the hemo-concentrator, and the one inlet tube thus form a closed fluid circulation circuit by which a pump can recycle the blood through the hemo-concentrator. One aspect of the invention includes a hemo-concentrator system and a specially adapted tubing set, for easily and quickly converting the hemo-concentrator from conventional use to use in the blood recovery method. Other aspects of the invention are directed to the combination of tubing set with hemo-concentrator, and to the tubing set itself.

    摘要翻译: 本发明涉及血袋系统,其包括限定上端和下端的基本上透明的生物相容材料的封闭的无菌袋; 袋子上端的输液口; 在袋的下端的出口; 在袋的下端的入口端口; 具有入口和出口的血液浓缩器; 一对入口管,其流体地连接到所述血液浓缩器入口; 以及一对流体连接到血液浓缩器出口的出口管。 一个入口管流体地连接到袋的出口,并且一个出口管流体地连接到袋的入口。 入口管和另一个出口管中的另一个被暂时密封(例如夹紧)以防止流过其中。 因此,袋子,一个出口管,血液浓缩器和一个入口管形成封闭的流体循环回路,通过该循环回路,泵可以通过血液浓缩器回收血液。 本发明的一个方面包括血液浓缩器系统和特别适合的管组,用于将血液浓缩器从常规用途容易地快速地转换成用于血液回收方法。 本发明的其它方面涉及管集合与血液浓缩器的组合以及管组本身。

    Systems and methods for sensing red blood cell hematocrit
    55.
    发明授权
    Systems and methods for sensing red blood cell hematocrit 有权
    用于感测红细胞血细胞比容的系统和方法

    公开(公告)号:US06419822B2

    公开(公告)日:2002-07-16

    申请号:US09901986

    申请日:2001-07-10

    IPC分类号: B01D1712

    摘要: Red blood cell sensing systems and methods rely upon straightforward measurement geometries. The systems and methods comprise an incident light source, an optical sensor, and a blood collection tube. The systems and methods hold the blood collection tube a predetermined radial distance from the incident light source where a linear relationship exists between sensed reflected light measured by the optical sensor and red blood cell hematocrit in a range of at least 10 to 90. The systems and methods make possible accurate red blood sensing without use of special optical cuvettes, mirrors, or focusing lenses. The systems and methods also make possible the use of standard transparent plastic tubing, without reliance upon special optical cuvettes.

    摘要翻译: 红细胞感测系统和方法依赖于简单的测量几何。 系统和方法包括入射光源,光学传感器和采血管。 系统和方法将采血管保持与入射光源预定的径向距离,其中在由光学传感器测量的感测反射光与红细胞血细胞比容之间存在线性关系,范围在至少10至90°。系统和 方法可以在不使用特殊的光学比色杯,镜子或聚焦镜片的情况下进行准确的红血传感。 系统和方法也可以使用标准的透明塑料管,而不依赖于特殊的光学比色皿。

    Cardiopulmonary bypass blood recovery method
    56.
    发明授权
    Cardiopulmonary bypass blood recovery method 有权
    心肺旁路血液回收法

    公开(公告)号:US06398751B1

    公开(公告)日:2002-06-04

    申请号:US09189230

    申请日:1998-11-11

    申请人: Keith Samolyk

    发明人: Keith Samolyk

    IPC分类号: A61M3700

    摘要: A method and blood bag, whereby a substantial volume of concentrated whole blood can be quickly and easily recovered from the cardiopulmonary bypass (CPB) circuit of a patient immediately following cardiac or thoracic vascular surgery. This is achieved in an operating room, by transferring most of the blood in the CPB circuit into a sterile bag located in the surgical field, removing the bag with blood from the surgical field, and outside the surgical field, but preferably in the operating room, hemo-concentrating the blood in the bag, while the bag is fluidly connected to the bypass system hardware. A novel blood bag (or hemo-bag) system is especially adapted for use with the method of the present invention. The new hemo-bag system comprises a closed, sterile bag of substantially transparent, bio-compatible material, defining upper and lower ends. An infusion port is located at the upper end of the bag. An outlet port, an inlet port, and an IV line are situated at the lower end of the bag. A baffle is preferably located inside the bag, for directing upward flow entering the bag through the inlet port, away from the outlet port. Each of the ports and line terminate in connector structure, and can be opened or closed by way of conventional clips and caps.

    摘要翻译: 一种方法和血袋,其中大量体积的浓缩全血可以快速且容易地从心脏或胸廓血管手术后的患者的体外循环(CPB)回路中恢复。 这在手术室中实现,通过将CPB电路中的大部分血液转移到位于外科手术领域的无菌袋中,从外科手术区域外部和外部外部移除袋,但优选在手术室 ,将血液集中在袋中,同时袋与流体连接到旁路系统硬件。 一种新颖的血袋(或血袋)系统特别适用于本发明的方法。 新的血液袋系统包括封闭的无菌袋,其基本上透明,生物相容的材料,限定上端和下端。 输液口位于袋子的上端。 出口端口,入口端口和IV线路位于袋子的下端。 优选地,挡板位于袋内,用于引导通过入口进入袋的向上流动,远离出口。 每个端口和管线终止于连接器结构,并且可以通过常规夹子和盖子打开或关闭。