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51.
公开(公告)号:US20040199098A1
公开(公告)日:2004-10-07
申请号:US10827951
申请日:2004-04-20
IPC分类号: A61M037/00
CPC分类号: A61M1/3693 , A61M1/02 , A61M1/0209 , A61M1/0222 , A61M1/302 , A61M1/303 , A61M1/308 , A61M1/3603 , A61M1/3633 , A61M1/3696 , A61M1/385 , A61M2202/0427 , A61M2202/0429 , A61M2205/33 , A61M2205/3393 , A61M2205/60 , A61M2230/207 , A61M2202/0014 , A61M2202/0021
摘要: Blood processing systems and methods convey blood drawn from a donor through a blood processing circuit to separate the blood into at least one targeted blood component for collection. The systems and methods derive an estimated effect of the procedure upon the donor. The estimated effect can be expressed in terms of a net blood fluid volume loss, or as a hematocrit of the donor after completion of the desired blood collection procedure. The systems and methods present the estimated effect to an operator for viewing, reading, or offloading.
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公开(公告)号:US06716151B2
公开(公告)日:2004-04-06
申请号:US10125995
申请日:2002-04-19
申请人: Ivo Panzani , Sergio Romagnoli , Massimo Belloni
发明人: Ivo Panzani , Sergio Romagnoli , Massimo Belloni
IPC分类号: B04B1300
CPC分类号: B04B15/12 , A61M1/0281 , A61M1/3692 , A61M1/3693 , A61M1/3696 , A61M2230/207 , B04B5/0442 , B04B13/00
摘要: A method and apparatus for controlling the washing step in a blood centrifugation cell in which washing solution is introduced into the blood centrifugation cell and the cell contains compacted red cells and supernatant at the beginning of the washing step. The apparatus can comprise various sensors and a computer. The sensors sense and transmit to the computer three inputs. The first input is indicative of the total volume of blood that enters the cell during the filling step and the total amount of washing solution that enters the cell during the washing step. The second input is indicative of the hematocrit value of the blood introduced during the filling step. The third input is indicative of the geometric characteristics of the cell. Based on the inputs, the computer executes an algorithm that produces a first output that is the concentration of the supernatant in the supernatant-washing solution mixture.
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公开(公告)号:US20030138349A1
公开(公告)日:2003-07-24
申请号:US10265297
申请日:2002-10-03
发明人: Thomas C. Robinson , Thomas P. Sahines , Richard R. D'Elia , Robert K. Fernandez , Frank Hickman
IPC分类号: A61M001/14 , A61M037/00 , C02F009/00
CPC分类号: A61M1/342 , A61M1/02 , A61M1/0218 , A61M1/024 , A61M1/025 , A61M1/0272 , A61M1/0281 , A61M1/34 , A61M1/3458 , A61M1/3489 , A61M1/3496 , A61M1/36 , A61M1/3603 , A61M1/3633 , A61M1/3672 , A61M2205/125 , A61M2205/126 , A61M2205/128 , A61M2205/3306 , A61M2205/3334 , A61M2205/3368 , A61M2205/3606 , A61M2205/3673 , A61M2205/50 , A61M2230/207
摘要: A blood processing system (2), includes a housing (4), to which a user control panel is mounted, having an access opening (47) therein. A cassette assembly (22), mounted to the housing for movement between a use position covering the access opening and a cassette-replacement position, includes a cassette holder and cassette (26) removably mounted to the holder. The cassette includes in part by tubing aligned with a through-hole (45) in the cassette. A door (34) is mounted to the housing for movement between a latched position, capturing the cassette between the panel and the door, and a released position. Independently-driven roller assemblies (46, 54, 72) pass part-way through the access opening to capture first tubing portions (44A, 52A, 68A) between the roller tracks (100, 102, 104) and the roller assemblies for peristaltic pumping of fluid. A number of movable pinch elements (48, 80, 90, 96) are extendable through the front panel to selectively pinch the tubing against the door and thus seal the tubing.
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公开(公告)号:US20020147440A1
公开(公告)日:2002-10-10
申请号:US10159553
申请日:2002-05-31
发明人: Keith A. Samolyk
IPC分类号: A61B019/00 , A61M005/32 , A61M037/00
CPC分类号: A61J1/10 , A61M1/0281 , A61M1/34 , A61M1/3603 , A61M1/3646 , A61M1/3666 , A61M2205/3331 , A61M2205/3368 , A61M2230/207 , Y10S128/24
摘要: The invention is directed to a blood bag system, comprising a closed, sterile bag of substantially transparent, bio-compatible material, defining upper and lower ends; an infusion port at the upper end of the bag; an outlet port at the lower end of the bag; an inlet port at the lower end of the bag; a hemo-concentrator having an inlet port and an outlet port; a pair of inlet tubes fluidly connected to the hemo-concentrator inlet port; and a pair of outlet tubes fluidly connected to the hemo-concentrator outlet port. One of the inlet tubes is fluidly connected to the outlet port of the bag, and one of the outlet tubes fluidly connected to the inlet port of the bag. The other of the inlet tubes and the other of the outlet tubes are temporarily sealed (e.g., clamped) to prevent flow therethrough. The bag, the one outlet tube, the hemo-concentrator, and the one inlet tube thus form a closed fluid circulation circuit by which a pump can recycle the blood through the hemo-concentrator. One aspect of the invention includes a hemo-concentrator system and a specially adapted tubing set, for easily and quickly converting the hemo-concentrator from conventional use to use in the blood recovery method. Other aspects of the invention are directed to the combination of tubing set with hemo-concentrator, and to the tubing set itself.
摘要翻译: 本发明涉及血袋系统,其包括限定上端和下端的基本上透明的生物相容材料的封闭的无菌袋; 袋子上端的输液口; 在袋的下端的出口; 在袋的下端的入口端口; 具有入口和出口的血液浓缩器; 一对入口管,其流体地连接到所述血液浓缩器入口; 以及一对流体连接到血液浓缩器出口的出口管。 一个入口管流体地连接到袋的出口,并且一个出口管流体地连接到袋的入口。 入口管和另一个出口管中的另一个被暂时密封(例如夹紧)以防止流过其中。 因此,袋子,一个出口管,血液浓缩器和一个入口管形成封闭的流体循环回路,通过该循环回路,泵可以通过血液浓缩器回收血液。 本发明的一个方面包括血液浓缩器系统和特别适合的管组,用于将血液浓缩器从常规用途容易地快速地转换成用于血液回收方法。 本发明的其它方面涉及管集合与血液浓缩器的组合以及管组本身。
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公开(公告)号:US06419822B2
公开(公告)日:2002-07-16
申请号:US09901986
申请日:2001-07-10
IPC分类号: B01D1712
CPC分类号: B01D21/302 , A61M1/0236 , A61M1/367 , A61M1/3696 , A61M1/38 , A61M2205/128 , A61M2205/3393 , A61M2230/207 , B01D17/0217 , B01D21/2444 , B01D21/245 , B01D21/26 , B01D21/262 , B01D21/34 , B01D2221/08 , B01D2221/10
摘要: Red blood cell sensing systems and methods rely upon straightforward measurement geometries. The systems and methods comprise an incident light source, an optical sensor, and a blood collection tube. The systems and methods hold the blood collection tube a predetermined radial distance from the incident light source where a linear relationship exists between sensed reflected light measured by the optical sensor and red blood cell hematocrit in a range of at least 10 to 90. The systems and methods make possible accurate red blood sensing without use of special optical cuvettes, mirrors, or focusing lenses. The systems and methods also make possible the use of standard transparent plastic tubing, without reliance upon special optical cuvettes.
摘要翻译: 红细胞感测系统和方法依赖于简单的测量几何。 系统和方法包括入射光源,光学传感器和采血管。 系统和方法将采血管保持与入射光源预定的径向距离,其中在由光学传感器测量的感测反射光与红细胞血细胞比容之间存在线性关系,范围在至少10至90°。系统和 方法可以在不使用特殊的光学比色杯,镜子或聚焦镜片的情况下进行准确的红血传感。 系统和方法也可以使用标准的透明塑料管,而不依赖于特殊的光学比色皿。
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公开(公告)号:US06398751B1
公开(公告)日:2002-06-04
申请号:US09189230
申请日:1998-11-11
申请人: Keith Samolyk
发明人: Keith Samolyk
IPC分类号: A61M3700
CPC分类号: A61J1/10 , A61M1/0281 , A61M1/34 , A61M1/3603 , A61M1/3646 , A61M1/3666 , A61M1/3667 , A61M2230/207 , Y10S128/03 , Y10S128/24
摘要: A method and blood bag, whereby a substantial volume of concentrated whole blood can be quickly and easily recovered from the cardiopulmonary bypass (CPB) circuit of a patient immediately following cardiac or thoracic vascular surgery. This is achieved in an operating room, by transferring most of the blood in the CPB circuit into a sterile bag located in the surgical field, removing the bag with blood from the surgical field, and outside the surgical field, but preferably in the operating room, hemo-concentrating the blood in the bag, while the bag is fluidly connected to the bypass system hardware. A novel blood bag (or hemo-bag) system is especially adapted for use with the method of the present invention. The new hemo-bag system comprises a closed, sterile bag of substantially transparent, bio-compatible material, defining upper and lower ends. An infusion port is located at the upper end of the bag. An outlet port, an inlet port, and an IV line are situated at the lower end of the bag. A baffle is preferably located inside the bag, for directing upward flow entering the bag through the inlet port, away from the outlet port. Each of the ports and line terminate in connector structure, and can be opened or closed by way of conventional clips and caps.
摘要翻译: 一种方法和血袋,其中大量体积的浓缩全血可以快速且容易地从心脏或胸廓血管手术后的患者的体外循环(CPB)回路中恢复。 这在手术室中实现,通过将CPB电路中的大部分血液转移到位于外科手术领域的无菌袋中,从外科手术区域外部和外部外部移除袋,但优选在手术室 ,将血液集中在袋中,同时袋与流体连接到旁路系统硬件。 一种新颖的血袋(或血袋)系统特别适用于本发明的方法。 新的血液袋系统包括封闭的无菌袋,其基本上透明,生物相容的材料,限定上端和下端。 输液口位于袋子的上端。 出口端口,入口端口和IV线路位于袋子的下端。 优选地,挡板位于袋内,用于引导通过入口进入袋的向上流动,远离出口。 每个端口和管线终止于连接器结构,并且可以通过常规夹子和盖子打开或关闭。
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公开(公告)号:US12083258B2
公开(公告)日:2024-09-10
申请号:US17825918
申请日:2022-05-26
申请人: Fenwal, Inc.
CPC分类号: A61M1/3496 , A61M1/34 , A61M1/3403 , A61M1/3607 , A61M1/3609 , A61M1/3616 , A61M1/362262 , A61M1/362266 , A61M1/3643 , A61M1/3672 , A61M1/38 , A61M1/382 , A61M1/385 , G01N33/48 , G16H10/60 , G16H40/60 , A61M2202/0415 , A61M2205/33 , A61M2205/3334 , A61M2205/3379 , A61M2205/3393 , A61M2205/502 , A61M2205/505 , A61M2230/207
摘要: A system for collecting plasma comprises a separator to separate whole blood from a donor into a plasma product and red blood cells, an anticoagulant line to introduce anticoagulant to the whole blood, a touchscreen, and a controller. The controller is configured to receive donor parameters electronically from a donor management system. The controller is configured to use a target volume for plasma product and/or raw plasma which is based at least in part on donor height and weight used to calculate total donor blood volume, the target volume for plasma product and/or raw plasma based on the total donor blood volume. The controller is configured to control the system to operate at least three draw and return phases to withdraw whole blood from a donor and separate the whole blood into the plasma product and the red blood cells and to return the red blood cells to the donor.
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公开(公告)号:US12064544B2
公开(公告)日:2024-08-20
申请号:US16906976
申请日:2020-06-19
发明人: Dennis Briggs , Simon Do , Eric Rabeno , Abdoulaye Sangare , Mark Vandlik , Vicki Fluck , Christopher Turek
CPC分类号: A61M1/3696 , A61M1/0209 , A61M1/3609 , A61M1/36222 , A61M1/36225 , A61M1/362264 , A61M1/362266 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3652 , A61M1/3683 , A61M2202/0439 , A61M2205/051 , A61M2205/053 , A61M2205/3331 , A61M2205/3334 , A61M2205/6018 , A61M2230/207 , G01M3/26
摘要: A photopheresis system (200) is disclosed, and that may be configured to execute one or more protocols. These protocols include: 1) protocols (400; 430; 460) for purging air out of a centrifuge bowl (210) used by the photopheresis system (200); 2) protocols (500; 510 550) for assessing the installation/operation of one or more pressure domes (330) used by the photopheresis system (200); and 3) protocols (580; 600; 660; 700; 740) for collecting buffy coat from blood processed by the photopheresis system (200).
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59.
公开(公告)号:US11904113B2
公开(公告)日:2024-02-20
申请号:US17077793
申请日:2020-10-22
申请人: Roivios Limited
CPC分类号: A61M25/04 , A61M1/73 , A61M1/74 , A61M1/743 , A61M1/75 , A61M1/80 , A61M1/84 , A61M25/007 , A61M25/0017 , A61M25/0023 , A61M25/0026 , A61M25/0041 , A61M25/0108 , A61M25/1025 , A61M25/10 , A61M39/12 , A61M2025/0213 , A61M2202/0496 , A61M2205/3303 , A61M2205/3317 , A61M2205/3334 , A61M2205/3368 , A61M2205/52 , A61M2205/583 , A61M2210/1082 , A61M2210/1085 , A61M2210/1089 , A61M2230/00 , A61M2230/207 , A61M2230/50 , A61M2230/65
摘要: A ureteral catheter is provided, including a drainage lumen including a proximal portion and a distal portion configured to be positioned in a patient's kidney, renal pelvis, and/or in the ureter adjacent to the renal pelvis, the distal portion including a retention portion for maintaining positioning of the distal portion of the drainage lumen, the retention portion including at least two openings on a sidewall of the retention portion for permitting fluid flow into the drainage lumen wherein a total area of a proximal most opening of the at least two openings is less than a total area of more distal opening(s) nearer to the distal end of the drainage lumen, and wherein when negative pressure is applied through the ureteral catheter, fluid is drawn into the ureteral catheter through the at least two openings.
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公开(公告)号:US11865243B2
公开(公告)日:2024-01-09
申请号:US16328443
申请日:2017-08-30
发明人: Mark T. Wyeth , Robert Paul McCarty , Gregory Yantz , James Ian Johnson , Joseph E. Turk, Jr. , James M. Brugger , Jeffrey H. Burbank
CPC分类号: A61M1/3639 , A61M1/1611 , A61M1/1621 , A61M1/3623 , A61M2205/3344 , A61M2205/52 , A61M2230/207
摘要: A blood treatment system with pressure sensors may be configured to control blood flow to and from the patient and use readings of the pressure sensors to determine a change in a pressure drop across a flow restriction in the blood circuit to estimate a condition of the machine or the patient, or outputting data responsive to the estimation. Further embodiments employ measurement of pressure drop to detect abnormal viscosity or viscosity variations in order to detect possible infection.
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