公开(公告)号：US20170268037A1

公开(公告)日：2017-09-21

申请号：US15310083

申请日：2015-05-15

Applicant: FLUXION BIOSCIENCES, INC.

Inventor： CRISTIAN IONESCU-ZANETTI ,  MICHAEL SCHWARTZ ,  CHRISTINE TING FU ,  RONG ANDREA FAN

IPC: C12Q1/68 ,  B03C1/28 ,  B03C1/01 ,  B03C1/033 ,  B01L3/00 ,  B03C1/30

CPC classification number: C12Q1/6806 ,  B01L3/502761 ,  B01L2200/0652 ,  B01L2400/043 ,  B03C1/01 ,  B03C1/0332 ,  B03C1/288 ,  B03C1/30 ,  B03C2201/18 ,  B03C2201/26 ,  C12M47/02 ,  C12N11/14 ,  G01N33/54326 ,  C12Q2563/143 ,  C12Q2563/149

Abstract: A method is provided including coupling magnetic beads to a population of cells in a fluid sample to form magnetically-labeled cells, magnetically separating the magnetically-labeled cells from non-magnetically-labeled cells in the fluid sample, and separating target cells from non-target cells of the magnetically-labeled cells based on a size difference between the magnetically-labeled target cells and the magnetically-labeled non-target cells. A microfluidic device is provided including a fluidic pathway traversing a magnetic isolation region and a size-based isolation region. The magnetic isolation region includes a magnet positioned to separate magnetically-labeled cells from non-magnetically labeled cells in the magnetic isolation region. The size-based isolation region includes a separator configured to separate cells less than a threshold size from cells greater than a threshold size.

公开(公告)号：US20170266653A1

公开(公告)日：2017-09-21

申请号：US15614944

申请日：2017-06-06

Applicant: ADVANCED LIQUID LOGIC, INC.

Inventor： Michael G. POLLACK ,  Ramakrishna SISTA ,  Zhishan HUA ,  Vamsee K. PAMULA ,  Arjun SUDARSAN ,  Vijay SRINIVASAN ,  Prasanna THWAR ,  Alexander SHENDEROV ,  Dwayne ALLEN

IPC: B01L3/02 ,  B03C1/28 ,  B01F13/08 ,  B01L3/00 ,  B01F13/00 ,  B03C1/01

CPC classification number: B01F13/0023 ,  B01F13/002 ,  B01F13/0071 ,  B01F13/0076 ,  B01F13/0818 ,  B01L3/502 ,  B01L3/502715 ,  B01L3/502792 ,  B01L2200/027 ,  B01L2200/0631 ,  B01L2200/0657 ,  B01L2200/0668 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2400/043 ,  B01L2400/0478 ,  B03C1/01 ,  B03C1/0332 ,  B03C1/0335 ,  B03C1/284 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  Y10T436/25

Abstract: Methods of concentrating beads in a droplet and/or loading beads on a fluidic device are provided, including among other things, a method of concentrating beads in a droplet, the method comprising: (a) providing a droplet actuator comprising: (i) an interior droplet operations volume; and (ii) a reservoir exterior to the interior volume; (iii) a droplet established in a liquid path extending from the reservoir into the interior volume; (b) providing magnetically responsive beads in the portion of the droplet which is in the reservoir; (c) magnetically attracting the magnetically responsive beads through the liquid path into the portion of the droplet which is in the interior volume; and (d) forming a droplet comprising one or more of the magnetically responsive beads in the interior volume.

公开(公告)号：US20170240440A1

公开(公告)日：2017-08-24

申请号：US15048446

申请日：2016-02-19

Applicant: Meiju SHAO

Inventor： Meiju SHAO

IPC: C02F1/48 ,  B03C1/30 ,  B01D35/06

CPC classification number: C02F1/488 ,  B01D29/35 ,  B01D29/902 ,  B01D29/906 ,  B01D35/06 ,  B01D35/30 ,  B01D36/001 ,  B01D2201/347 ,  B03C1/0332 ,  B03C1/286 ,  B03C1/288 ,  B03C1/30 ,  B03C2201/18 ,  B03C2201/28 ,  C02F1/001 ,  C02F1/481 ,  C02F2101/10 ,  C02F2101/20

Abstract: The present disclosure relates to a filter, which comprises a housing, a protective bushing, a magnetic bar and a filter screen. The protective bushing, the magnetic bar and the filter screen are disposed in the housing. The protective bushing comprises a cavity and a channel. The channel is disposed along the axial direction of the cavity. The advantageous effects of the filter according to the present disclosure lies in that: the magnetic bar inside the filter can adsorb metal impurities in the water in the channel; and the channel is in S shape which can increase the length of the flow path of the water so that the metal impurities in the water can be guaranteed to be sufficiently adsorbed by the magnetic bar; and the filter screen can filter out non-metal impurities in the water. An exhaust valve provided at the top of the protective bushing can keep the balance between the air pressure inside the filter and the air pressure outside the filter, which can ensure that the water can flow out and in smoothly. The filter is attached with an operating handle. If the user wants to disassemble the filter to clear up the metal impurities and non-metal impurities in the filter, he can disassemble the filter by means of the operating handle without the need of professional operator, which is convenient and simple.

公开(公告)号：USD793523S1

公开(公告)日：2017-08-01

申请号：US29560412

申请日：2016-04-06

Applicant: Adey Holdings (2008) Limited

Designer： Christopher Adey ,  Simon Downie ,  Kashem Pathan

CPC classification number: F24D19/0092 ,  B01D21/0003 ,  B01D21/0009 ,  B01D21/2483 ,  B01D21/267 ,  B03C1/02 ,  B03C1/0332 ,  B03C1/286 ,  B03C2201/18 ,  B03C2201/20 ,  B03C2201/28 ,  F16L37/565

Abstract: A sleeve 26 for a magnet assembly 28 of a magnetic separator for use in a central heating system comprises first and second sleeve members 29, 30, and a connection 31 for connecting respective ends of the first and second sleeve members 29, 30 together.

公开(公告)号：US09718066B2

公开(公告)日：2017-08-01

申请号：US14770059

申请日：2014-12-15

Applicant: SIEMENS AKTIENGESELLSCHAFT

Inventor： Werner Hartmann ,  Theresa Stark ,  Sonja Wolfrum ,  Hermann Wotruba

IPC: B03C1/00 ,  B03C1/30 ,  B03B1/04 ,  B03B7/00 ,  B03B9/00 ,  B03D1/08

CPC classification number: B03C1/30 ,  B03B1/04 ,  B03B7/00 ,  B03B9/00 ,  B03C2201/18 ,  B03D1/085 ,  B03D2203/02

Abstract: A defined mineral phase is separated from a ground ore having several chemical phases and being present in a heterogeneous particle size distribution by classifying the ore according to a defined particle diameter into at least two fractions, a first fraction having particles essentially larger than the defined particle diameter and a second fraction having particles essentially smaller than the defined particle diameter, and the defined mineral particles of value being present in both fractions, floating the first fraction having the greater particle diameters and selecting the defined mineral particles of value in a flotation concentrate, selectively admixing the defined mineral particles of value in the fraction having the smaller particle diameters with magnetizable particles, applying a magnetic separation process to the second fraction having smaller particle diameters, and separating a concentrate with an enrichment of the defined mineral phase of value.

公开(公告)号：US09714945B2

公开(公告)日：2017-07-25

申请号：US14201744

申请日：2014-03-07

Applicant: Miltenyi Biotec GmbH

Inventor： Stefan Miltenyi ,  Winfried Schimmelpfennig ,  Holger Lantow ,  Elmar Niklas Neuschäfer ,  Martin Biehl ,  Eiad Kabaha ,  Jürgen Schulz

IPC: G01N33/58 ,  A61M1/36 ,  B03C1/28 ,  B04B5/04 ,  B04B13/00 ,  C12M1/26 ,  C12M1/00 ,  B01D21/26 ,  B04B5/00 ,  B04B5/10 ,  B04B1/12 ,  B04B7/08 ,  G01N35/00 ,  B01D15/38 ,  C12N5/0789 ,  C12N5/077 ,  C12N5/0783 ,  B03C1/032 ,  B03C1/00 ,  B03C1/027 ,  B03C1/033 ,  B03C1/034 ,  A61M1/02

CPC classification number: G01N33/58 ,  A61M1/0209 ,  A61M1/3618 ,  A61M1/3633 ,  A61M1/3679 ,  A61M1/3692 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2202/0071 ,  A61M2202/0413 ,  A61M2202/0427 ,  A61M2202/10 ,  B01D15/3809 ,  B01D15/3885 ,  B01D21/26 ,  B03C1/002 ,  B03C1/027 ,  B03C1/032 ,  B03C1/0332 ,  B03C1/0335 ,  B03C1/034 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  B04B1/12 ,  B04B5/00 ,  B04B5/04 ,  B04B5/0442 ,  B04B5/10 ,  B04B7/08 ,  B04B13/00 ,  B04B2005/0464 ,  B04B2013/006 ,  C12M23/28 ,  C12M33/10 ,  C12M41/48 ,  C12M47/04 ,  C12N5/0636 ,  C12N5/0646 ,  C12N5/0647 ,  C12N5/0669 ,  G01N35/0098 ,  G01N2333/70596

Abstract: The invention relates to a centrifuge for separating a sample into at least two components, comprising a chamber for receiving a sample to be centrifuged. According to the invention, the centrifuge further comprises a means for controlling the progress of the sample separation is located at the chamber.

公开(公告)号：US20170199107A1

公开(公告)日：2017-07-13

申请号：US14990972

申请日：2016-01-08

Applicant: Gilson, Inc. ,  Salus Discovery LLC

Inventor： David John Guckenberger ,  Mary Christin Regier

IPC: G01N1/40 ,  G01N35/00 ,  B03C1/32 ,  B01L3/00

CPC classification number: G01N1/40 ,  B01L3/502 ,  B01L2300/06 ,  B01L2300/0609 ,  B01L2300/0829 ,  B03C1/32 ,  B03C2201/18 ,  G01N35/0098 ,  G01N2001/4038 ,  G01N2035/00564

Abstract: A magnetic base for a sample plate of a sample processing system is provided comprising a first plate comprising a first top surface; a bottom surface; and a sample plate mounting cavity wall mounted to the first top surface, wherein the first plate and the sample plate mounting cavity wall define a sample plate mounting cavity configured to accommodate a sample plate of a sample processing system. The magnetic base further comprises a second plate extending parallel to the first plate, the second plate comprising a second top surface; and a magnet mounting cavity wall extending between the bottom surface of the first plate and the second top surface of the second plate, wherein the first plate, the second plate, and the magnet mounting cavity wall define a magnet mounting cavity configured to accommodate a free floating magnet.

公开(公告)号：US09694368B2

公开(公告)日：2017-07-04

申请号：US13509232

申请日：2010-11-12

Applicant: Hideji Tajima

Inventor： Hideji Tajima

IPC: A61K9/00 ,  B03C1/015 ,  B03C1/28 ,  G01N33/543

CPC classification number: B03C1/015 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N33/54326

Abstract: The present invention relates to a magnetic reagent, a magnetic reagent kit, a method for treating magnetic carriers, and a treatment device therefor, with an object of quickly and efficiently treating magnetic carriers of a micro particle diameter including nanosized magnetic carriers.The magnetic reagent or magnetic reagent kit includes: a plurality of magnetic carriers which can be magnetized by being exposed to a magnetic field, can be bonded to a predetermined chemical substance or living organism in a liquid, and that have a particle diameter that enables them to be suspended in the liquid; and a plurality of treatment promoting magnetic particles which can be magnetized by being exposed to a magnetic field and thus can have the magnetic carriers adsorbed on the surface thereof, are formed so that they can be moved within the liquid by movement of the liquid or by a magnetic field, and promote a treatment for capturing or re-suspension of the magnetic carriers.

公开(公告)号：US09683417B2

公开(公告)日：2017-06-20

申请号：US14414629

申请日：2013-07-29

Applicant: Romar International Limited

Inventor： Martin McKenzie

IPC: E21B21/06 ,  B03C1/24 ,  B03C1/033 ,  B03C1/20 ,  B03C1/28

CPC classification number: E21B21/065 ,  B03C1/0332 ,  B03C1/20 ,  B03C1/24 ,  B03C1/286 ,  B03C2201/18 ,  B03C2201/20

Abstract: The invention provides an apparatus (10) for removing magnetic particles (53) from a liquid flowing from an oil or gas operation and method of use. The apparatus (10) comprises a plurality of magnet assemblies (20), each having a first condition in which an operable part is active to attract magnetic particles (53) to the magnet assembly (20), and a second condition in which the operable part is inactive and magnetic particles (53) are not attracted to the magnet assembly (20). A drive mechanism (13) moves the magnet assemblies (20) between exposure to a flow path of from a liquid (40) flowing from an oil or gas operation and a collection location (54). An activation means (36) moves the magnet assemblies (20) between the first condition and the second condition.

公开(公告)号：US20170165678A1

公开(公告)日：2017-06-15

申请号：US15355638

申请日：2016-11-18

Applicant: Industrial Technology Research Institute

Inventor： Ming-Da YANG ,  Mean-Jue TUNG ,  Yu-Ting HUANG

IPC: B03C1/033 ,  B03C1/01 ,  H01F7/02

CPC classification number: B03C1/033 ,  B03C1/01 ,  B03C1/034 ,  B03C2201/18 ,  B03C2201/26 ,  H01F7/0205

Abstract: A magnetic separator including a magnetic structure is provided. The magnetic structure includes magnetic structure units. The magnetic structure units form at least one continuous fluid channel. Each of the magnetic structure units has at least one protrusion. The magnetic structure has the protrusions facing towards each other between at least a portion of the adjacent two magnetic structure units.