Abstract:
Increasing signal to noise ratio in optical spectra obtained by spectrophotometers. An interferometer introduces interference effects into a source light beam. A dual beam configuration splits the source beam having the interference effects into a reference beam and a sample beam. The reference beam interacts with a reference substance and is detected by a reference detector. The sample beam interacts with a sample substance and is detected by a sample detector. An optical spectra of the sample is based on the difference between the detected reference beam and the detected sample beam.
Abstract:
A reflectometer for measuring absorption of light in selected regions of the light spectrum by a diffuse reflector. The reflectometer is adapted to precisely measure absorption resulting from the constituents present in body fluids. The sample to be measured is illuminated by a focussed light source at an angle of 45.degree. to its surface. The light diffusely reflected about the normal to the sample falls on a small round bundle of optical fibers. At the opposite end of the bundle, the fibers are arranged into a narrow rectangle. This rectangle forms the entrance slit for a concave holographic diffraction grating. The grating forms images of this entrance slit spectrally separated over a flat field suitable for recording the spectrum on film or on an array of discrete detectors.
Abstract:
A reflectometer for measuring absorption of light in selected regions of the light spectrum by a diffuse reflector. The reflectometer is adapted to precisely measure absorption resulting from the constituents present in body fluids. The sample to be measured is illuminated by a focused light source at an angle of 45.degree. to its surface. The light diffusely reflected about the normal to the sample falls on a small round bundle of optical fibers at the opposite end of the bundle, the fibers are arranged into a narrow rectangle. This rectangle forms the entrance slit for a concave holographic diffraction grating. The grating forms images of this entrance slit spectrally separated over a flat field suitable for recording the spectrum on film or on an array of discrete detectors.
Abstract:
A vaariable angle reflection accessory for use in reflection spectrometry characterized by a pair of fixed ellipsoidal reflectors positioned over the sample surface and a pair of rotatable plane mirrors positions at opposite sides of the sample surface. The spectrometer beam is brought to a focus at the first plane mirror, from which it is reflected off the first ellipsoidal reflector to a focus at the sample surface. The reflected beam follows a corresponding path back to the spectrometer. Rotating the mirrors in unison causes the beam angle of incidence on the sample surface to vary over a wide range while maintaining optical alignments and continuing to center the radiation on the same sample area.
Abstract:
An apparatus and method for determining the relative proportions of two eents of a ternary compound from light reflected off a sample of the compound. The light is varied in wavelength and a graph of reflectance vs wavelength is stored. For a given compound of general form A.sub.x B.sub.1-x C, x may be determined by converting the stored graph to a graph of reflectance vs photon energy of the light, determining the photon energy of the light for the longest wavelength peak on the converted graph, and computing x from the equation E.sub.1 =a+bx+cx.sup.2 wherein a, b, and c are predetermined constants, and E.sub.1 is the photon energy in electron volts of the peak of interest.
Abstract:
A portable analysis spectrometer (10) for field mineral identification is coupled to a microprocessor (11) and memory (12) through a bus (13) and A/D converter (14) to display (16) a spectrum of reflected radiation in a band selected by an adjustable band spectrometer (20) and filter (23). A detector array (21) provides output signals at spaced frequencies within the selected spectrometer band which are simultaneously converted to digital form for display. The spectrum displayed is compared with a collection of spectra for known minerals. That collection is stored in memory and selectively displayed with the measured spectrum, or stored in a separate portfolio. In either case, visual comparison is made. Alternatively, the microprocessor may use an algorithm to make the comparisons in search for the best match of the measured spectrum with one of the stored spectra to identify the mineral in the target area.
Abstract:
Disclosed are systems and methods utilizing an infrared probe and discriminating software to rapidly discriminate abnormal tissue processes from normal tissue during surgery, physical examination of in-situ lesions, and in the assessment of biopsy and resected tissue specimens. Examples demonstrate discrimination of cancerous from noncancerous tissues. The discriminating software, i.e. the metrics, algorithms, calibrant spectra, and decision equations, allows tissue to be identified as abnormal or normal using a minimum of infrared (IR) wavelengths in order to be measured rapidly. The probe records IR metrics approximately 1000 times faster than current commercial instruments, i.e. on a timescale fast enough for clinical use. The probe uses a tunable mid-infrared laser with a small set of selected wavelengths that are optimized for detecting the chemical and molecular signatures of tissue specific lesions to include, but not limited to, cancer, preneoplasia, intracellular accumulations (e.g. steatosis), inflammation, and wound healing.
Abstract:
In some embodiments, a system comprises a head-mounted frame removably coupleable to the user's head; one or more light sources coupled to the head-mounted frame and configured to emit light with at least two different wavelengths toward a target object in an irradiation field of view of the light sources; one or more electromagnetic radiation detectors coupled to the head-mounted member and configured to receive light reflected after encountering the target object; and a controller operatively coupled to the one or more light sources and detectors and configured to determine and display an output indicating the identity or property of the target object as determined by the light properties measured by the detectors in relation to the light properties emitted by the light sources.
Abstract:
Systems and methods utilize an infrared probe and discriminating software to rapidly discriminate normal tissue processes from normal tissue during surgery, physical examination of in-situ lesions, and in the assessment of biopsy and resected tissue specimens. Examples demonstrate discrimination of cancerous from noncancerous tissues. The discriminating software, i.e. the metrics, algorithms, calibrant spectra, and decision equations, allows tissue to be identified as abnormal or normal using a minimum of infrared (IR) wavelengths in order to be measured rapidly. The probe records IR metrics approximately 1000 times faster than current commercial instruments, i.e. on a timescale fast enough for clinical use. The probe uses a tunable mid-infrared laser with a small set of selected wavelengths that are optimized for detecting the chemical and molecular signatures of tissue specific lesions to include, but not limited to, cancer, preneoplasia, intracellular accumulations (e.g. steatosis), inflammation, and wound healing.
Abstract:
An information processing method includes the steps of calculating information on object illumination light for illuminating an object based on spatial distribution information of illumination light and orientation information of the object, and correcting information on the reflected light so as to reduce influence of the object illumination light based on the information on the object illumination light and information on the reflected light from the object.