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公开(公告)号：US08129031B2
公开(公告)日：2012-03-06
申请号：US12244594
申请日：2008-10-02
Applicant: Michael Tung-Kiung Ling , Moh-Ching Oliver Chang , Thomas John Myers , Ying-Cheng Lo
Inventor： Michael Tung-Kiung Ling , Moh-Ching Oliver Chang , Thomas John Myers , Ying-Cheng Lo
CPC classification number: B32B27/32 , B32B7/00 , B32B7/06 , B32B27/08 , B32B27/325 , B32B2250/24 , B32B2250/42 , B32B2274/00 , B32B2307/306 , B32B2307/31 , B32B2439/70 , B32B2439/80 , Y10T428/269 , Y10T428/31743 , Y10T428/31909
Abstract: Films containing microlayer structures are provided. In a general embodiment, the present disclosure provides an autoclavable film containing a first microlayer of a heat resistant polymer and a second microlayer of a flexible polymer attached to the first microlayer. Each of the first microlayer and the second microlayer has a thickness ranging between about 0.01 microns and about 10 microns.
Abstract translation: 提供了含有微层结构的薄膜。 在一般实施例中，本公开提供了一种耐高压灭菌膜，其包含耐热聚合物的第一微层和附着到第一微层的柔性聚合物的第二微层。 第一微层和第二微层中的每一个具有约0.01微米至约10微米的厚度。
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公开(公告)号：US20110009810A1
公开(公告)日：2011-01-13
申请号：US12498853
申请日：2009-07-07
Applicant: Ying-Cheng Lo , Alp Akonur , Yuanpang S. Ding
Inventor： Ying-Cheng Lo , Alp Akonur , Yuanpang S. Ding
IPC: A61M1/28
Abstract: Patients suffering from acute renal failure must be diagnosed and treated quickly so that a physician can confidently prescribe either peritoneal dialysis or hemodialysis. In one way of quickly treating the patients, software is used to calculate a suitable peritoneal dialysis prescription without regard to how short or how long a dialysis cycle is used, and without regard to a total dialysate fluid volume for a therapy. For patients with suitable peritoneal membrane transport properties, the software program suggests that, at least over a short period of time, unexpectedly high ultrafiltrate volumes and high clearances may be achieved.
Abstract translation: 患急性肾衰竭的患者必须迅速诊断和治疗，以便医生可以自信地开出腹膜透析或血液透析。 以快速治疗患者的一种方式，使用软件来计算合适的腹膜透析处方，而不考虑使用透析循环的短暂或多长时间，并且不考虑用于治疗的总透析液体积。 对于具有适当腹膜转运性质的患者，软件程序表明，至少在短时间内，可能会实现出乎意料的高超滤液体积和高清除率。
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公开(公告)号：US06994781B2
公开(公告)日：2006-02-07
申请号：US10031112
申请日：2001-07-03
Applicant: William H. Cork , James J. Ulmes , Richard L. West , Ying-Cheng Lo , Mark C. Weber , Kyungyoon Min
Inventor： William H. Cork , James J. Ulmes , Richard L. West , Ying-Cheng Lo , Mark C. Weber , Kyungyoon Min
IPC: B01D61/32
CPC classification number: A61B5/14546 , A61B5/14557 , A61B5/417 , A61B50/13 , A61B2562/028 , A61M1/0209 , A61M1/3609 , A61M1/367 , A61M1/3696 , A61M1/38 , A61M2205/12 , A61M2205/33 , A61M2205/52 , A61M2230/20 , B01D61/22 , G01N33/491 , G01N33/5005 , G01N33/5094 , G01N35/08 , G01N2035/00237 , Y10T436/117497
Abstract: A biological suspension processing system is disclosed that may include a suspension treatment device for treating one or more components of a biological suspension, a first fluid flow path for introducing a suspension into the treatment device and a second fluid flow path for withdrawing a constituent of the suspension from the device. At least on microelectromechanical (MEM) sensor communicates with one of the fluid flow paths for sensing a selected characteristic of the fluid therewith. The MEM sensor may be located elsewhere, such as on a container or bag and communicate with the interior for sensing a characteristic of the fluid contained therein. A wide variety of characteristics may be sensed, such as flow rate, pH, cell type, cell antigenicity, DNA, viral or bacterial presence, cholesterol, hematocrit, cell concentration, cell count, partial pressure, pathogen presence, or viscosity.
Abstract translation: 公开了一种生物悬浮处理系统，其可以包括用于处理生物悬浮液的一种或多种组分的悬浮处理装置，用于将悬浮液引入处理装置的第一流体流动路径和用于取出生物悬浮液的成分的第二流体流动路径 从设备暂停。 至少在微机电（MEM）传感器上与其中一个流体流路连通，以便感测流体的所选特征。 MEM传感器可以位于别处，例如在容器或袋上，并与内部连通，以便感测其中所含流体的特性。 可以检测各种各样的特征，例如流速，pH，细胞类型，细胞抗原性，DNA，病毒或细菌存在，胆固醇，血细胞比容，细胞浓度，细胞计数，分压，病原体存在或粘度。
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公开(公告)号：US20050269251A1
公开(公告)日：2005-12-08
申请号：US11198805
申请日：2005-08-05
Applicant: William Cork , James Ulmes , Richard West , Ying-Cheng Lo , Mark Weber , Kyungyoon Min
Inventor： William Cork , James Ulmes , Richard West , Ying-Cheng Lo , Mark Weber , Kyungyoon Min
IPC: G01N33/48 , A61B5/00 , A61B5/145 , A61B19/02 , A61M1/02 , A61M1/36 , A61M1/38 , A61M37/00 , B01D17/00 , B01D37/00 , B01D61/00 , B01D61/22 , B01L99/00 , C02F1/00 , C12M1/34 , G01N33/49 , G01N33/50 , G01N35/00 , G01N35/08 , G06F20060101 , G06F1/00 , B01D17/12
CPC classification number: A61B5/14546 , A61B5/14557 , A61B5/417 , A61B50/13 , A61B2562/028 , A61M1/0209 , A61M1/3609 , A61M1/367 , A61M1/3696 , A61M1/38 , A61M2205/12 , A61M2205/33 , A61M2205/52 , A61M2230/20 , B01D61/22 , G01N33/491 , G01N33/5005 , G01N33/5094 , G01N35/08 , G01N2035/00237 , Y10T436/117497
Abstract: A biological suspension processing system is disclosed that may include a suspension treatment device for treating one or more components of a biological suspension, a first fluid flow path for introducing a suspension into the treatment device and a second fluid flow path for withdrawing a constituent of the suspension from the device. At least one microelectromechanical (MEM) sensor communicates with one of the fluid flow paths for sensing a selected characteristic of the fluid therewith. The MEM sensor may be located elsewhere, such as on a container or bag and communicate with the interior for sensing a characteristic of the fluid contained therein. A wide variety of characteristics may be sensed, such as flow rate, pH, cell type, cell antigenicity, DNA, viral or bacterial presence, cholesterol, hematocrit, cell concentration, cell count, partial pressure, pathogen presence, or viscosity.
Abstract translation: 公开了一种生物悬浮处理系统，其可以包括用于处理生物悬浮液的一种或多种组分的悬浮处理装置，用于将悬浮液引入处理装置的第一流体流动路径和用于取出生物悬浮液的成分的第二流体流动路径 从设备暂停。 至少一个微机电（MEM）传感器与流体流动路径中的一个通信，用于感测流体的选定特性。 MEM传感器可以位于别处，例如在容器或袋上，并与内部连通，以便感测其中所含流体的特性。 可以检测各种各样的特征，例如流速，pH，细胞类型，细胞抗原性，DNA，病毒或细菌存在，胆固醇，血细胞比容，细胞浓度，细胞计数，分压，病原体存在或粘度。
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公开(公告)号：US06303200B1
公开(公告)日：2001-10-16
申请号：US09014217
申请日：1998-01-27
Applicant: Lecon Woo , Michael T. K. Ling , Patrick Balteau , Ying-Cheng Lo , Ketan Shah , Hénaut J. Eric , Yuan-pang Samuel Ding , Stanley Westphal , Robert Wojnarowski
Inventor： Lecon Woo , Michael T. K. Ling , Patrick Balteau , Ying-Cheng Lo , Ketan Shah , Hénaut J. Eric , Yuan-pang Samuel Ding , Stanley Westphal , Robert Wojnarowski
IPC: B29D2300
CPC classification number: A61L29/049 , C08F287/00 , C08L23/10 , C08L51/006 , C08L53/02 , C08L53/025 , C08L57/02 , Y10T428/139 , C08L23/12 , C08L2666/02 , C08L2666/04 , C08L2666/06
Abstract: A steam sterilizable monolayer medical tubing comprising a blend of a melt strength enhancing agent of a homopolymer or copolymer of polypropylene having free-end long chain branches of propylene units, a melt flow index of greater than 10 and in an amount of 1-10% by weight and a second component selected from the group of (i) a selectively hydrogenated block copolymer of a vinyl aromatic hydrocarbon and a conjugated diene and (ii) a selectively hydrogenated block copolymer of a vinyl aromatic hydrocarbon and a conjugated diene to which has been grafted, an alpha, beta-olenfically unsaturated monocarboxylic or dicarboxylic acid reagent.
Abstract translation: 一种蒸汽消毒单层医用管，其包含具有丙烯单元的自由端长支链的聚丙烯均聚物或共聚物的熔体强度增强剂的共混物，熔体流动指数大于10，量为1-10％ 和选自（i）乙烯基芳族烃和共轭二烯的选择性氢化嵌段共聚物和（ii）乙烯基芳族烃和共轭二烯的选择性氢化嵌段共聚物的第二组分，其中已经 接枝的α，β-烯烃不饱和单羧酸或二羧酸试剂。
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Patent Agency Ranking
公开(公告)号：US5733270A
公开(公告)日：1998-03-31
申请号：US474839
申请日：1995-06-07
Applicant: Michael T. K. Ling , Lecon Woo , Ying-Cheng Lo , Patrick Balteau , F. Peluso
Inventor： Michael T. K. Ling , Lecon Woo , Ying-Cheng Lo , Patrick Balteau , F. Peluso
CPC classification number: A61M39/162 , A61L29/16 , A61L2300/106 , A61L2300/404 , Y10S604/905
Abstract: An improved system and method for providing sterile connections. To this end, a device is provided comprising a body, a chamber defined, at least in part, by a portion of the body, the chamber including an interior having a solid sterilizing agent that can sublimate at ambient conditions, and a member that defines., in part, the chamber and is so constructed and arranged to allow the solid sterilizing agent to release in a rate controlled manner through the member.
Abstract translation: 用于提供无菌连接的改进的系统和方法。 为此，提供了一种装置，其包括主体，至少部分地由主体的一部分限定的室，所述室包括具有可在环境条件下升华的固体灭菌剂的内部，以及限定 部分地，腔室被构造和布置成允许固体灭菌剂以速率控制的方式通过构件释放。
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公开(公告)号：US5356709A
公开(公告)日：1994-10-18
申请号：US883009
申请日：1992-05-14
Applicant: Lecon Woo , Y. Wilson Cheung , Jerry D. Bartos , Michael T. K. Ling , Indrajit T. Patel , Ying-Cheng Lo
Inventor： Lecon Woo , Y. Wilson Cheung , Jerry D. Bartos , Michael T. K. Ling , Indrajit T. Patel , Ying-Cheng Lo
IPC: A61L29/00 , A61J1/10 , A61L29/04 , A61L29/08 , A61L31/00 , A61L31/04 , A61L31/10 , A61M1/00 , A61M5/14 , B32B27/08 , D02G3/00
CPC classification number: B32B27/08 , A61L29/049 , A61L29/085 , A61L31/041 , A61L31/10 , Y10T428/2933 , Y10T428/2935 , Y10T428/2947 , Y10T428/2975 , Y10T428/2998
Abstract: The present invention provides an improved coextruded medical grade port tubing. The medical grade port tubing provides characteristics that are desirable in the medical industry and therefore can be used as a medical port tubing in, for example, renal therapy or blood donor tubes. To this end, the present invention provides a non-PVC coextruded medical grade port tubing including: an outer layer comprising a blend of polypropylene copolymer and styrene-ethylene-butylene-styrene copolymer; a tie layer; and a core layer including a blend of polyamide and ethylene vinyl acetate.
Abstract translation: 本发明提供了一种改进的共挤出医用级端口管。 医疗级端口管道提供在医疗行业中期望的特征，因此可以用作例如肾脏治疗或献血管中的医疗端口管。 为此，本发明提供一种非PVC共挤出的医用级口管，其包括：包含聚丙烯共聚物和苯乙烯 - 乙烯 - 丁烯 - 苯乙烯共聚物的共混物的外层; 一个领带; 以及包含聚酰胺和乙烯 - 乙酸乙烯酯共混物的芯层。
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68.发明授权Methods of producing biaxially-oriented polymer product, and the product produced thereby 失效生产双轴取向聚合物产品的方法和由此生产的产品
公开(公告)号：US4874657A
公开(公告)日：1989-10-17
申请号：US933951
申请日：1986-11-24
Applicant: Ying-Cheng Lo , Darral V. Humphries
Inventor： Ying-Cheng Lo , Darral V. Humphries
IPC: B29C43/22 , B29C43/02 , B29C43/16 , B29C43/24 , B29C47/14 , B29C47/54 , B29C55/12 , B29C55/18 , B29C67/00 , B29K23/00 , B29L7/00
CPC classification number: B29C55/18 , B29C43/02 , B29C43/22 , B29C47/0023 , B29C47/14 , B29C47/54 , B29C55/12 , B29C67/0029 , B29K2995/0041 , B29K2995/0053 , Y10S428/91
Abstract: In accordance with the instant invention, biaxially-oriented polymer sheet is produced by continuously forging polymer feedstock between pairs of converging opposed surfaces. After it is biaxially-oriented, the sheet product is either cooled or heated while being restrained and advanced. The sheet produced by the process and apparatus has substantially uniform strain distribution over the width and length thereof as well as through the thickness thereof.
Abstract translation: 根据本发明，双轴取向聚合物片材通过在聚光相对表面对之间连续地锻造聚合物原料来制备。 在双轴取向后，片材产品被冷却或加热同时被限制和推进。 通过该方法和装置制造的片材在其宽度和长度上以及通过其厚度具有基本均匀的应变分布。
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公开(公告)号：US09132222B2
公开(公告)日：2015-09-15
申请号：US13458625
申请日：2012-04-27
Applicant: Robert W. Childers , Ying-Cheng Lo , Peter A. Hoping
Inventor： Robert W. Childers , Ying-Cheng Lo , Peter A. Hoping
CPC classification number: A61M1/284 , A61M1/28 , A61M1/281 , A61M1/282 , A61M2205/3379 , B01D61/30 , B01D61/32
Abstract: A system and method for automatically adjusting a Continuous Cycling Peritoneal Dialysis (“CCPD”) therapy to minimize the potential for excess intra-peritoneal volume. The adjustments are made at the end of the drain, just prior to the next fill. The adjustments short the next fill, if necessary, to limit the intra-peritoneal volume, add a cycle, if necessary, to use all of the available dialysis solution and will average the remaining dwell time to maximize the therapeutic benefit of the therapy in the allotted time. In another embodiment, a tidal therapy using trended patient UF data is provided.
Abstract translation: 一种用于自动调节连续循环腹膜透析（“CCPD”）治疗的系统和方法，以最大限度地减少腹膜内多余的体积。 调整是在排水结束时进行的，就在下一次填充之前。 如果需要，调整缩短下一次填充，以限制腹膜内体积，如果需要，添加一个循环，以使用所有可用的透析溶液，并将平均剩余停留时间，以最大化治疗的治疗效果 分配时间 在另一个实施例中，提供使用趋势化患者UF数据的潮汐治疗。
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70.发明授权公开(公告)号：US08868350B2
公开(公告)日：2014-10-21
申请号：US13088044
申请日：2011-04-15
Applicant: Alp Akonur , John Kenneth Leypoldt , Ying-Cheng Lo , Baris Ugur Agar
Inventor： Alp Akonur , John Kenneth Leypoldt , Ying-Cheng Lo , Baris Ugur Agar
CPC classification number: A61M1/1603 , A61M1/16 , A61M1/1611 , A61M1/1613 , A61M1/1619 , A61M1/3609 , A61M2202/0498 , A61M2205/15 , A61M2205/3584 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2230/20 , G06F19/3481
Abstract: A method of predicting serum phosphorus concentrations in a patient during hemodialysis includes measuring serum phosphorus concentrations of the patient over a hemodialysis treatment session time and an ultrafiltration rate calculated by a difference between pre- and post-dialytic body weight of the patient during an initial hemodialysis treatment session divided by a total treatment time of the treatment session and estimating a phosphorous mobilization clearance and a pre-dialysis distribution volume of phosphorus for the patient. Serum phosphorus concentrations of the patient can then be predicted at any time during any hemodialysis treatment session with the estimated phosphorous mobilization clearance and pre-dialysis distribution volume of phosphorus of the patient.
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