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    Apparatus and method for leak detection in a fluid-filled balloon useful to treat body tissue
    73.
    发明授权
    Apparatus and method for leak detection in a fluid-filled balloon useful to treat body tissue 失效
    用于治疗身体组织的流体填充球囊中的泄漏检测装置和方法

    公开(公告)号：US6057689A

    公开(公告)日：2000-05-02

    申请号：US905367

    申请日：1997-08-04

    申请人： Vahid Saadat

    发明人： Vahid Saadat

    IPC分类号： A61M25/00 ,  A61F2/958 ,  G01M3/18 ,  G01R31/12 ,  G01N27/00

    CPC分类号： G01M3/187

    摘要： An apparatus for detecting leaks in a fluid-filled device used to treat a patient's tissue includes an catheter having an expandable device defining a fluid reservoir about the distal end of the catheter. An internal electrode is in electrical contact with a conductive fluid within the fluid reservoir. A grounding electrode is outside of the fluid reservoir, in electrical contact with the patient's tissue. Voltage is supplied to the internal electrode and the grounding electrode. Where a leak occurs in the expandable device, conductive fluid will contact the patient's tissue, thus creating an electrical current path between the internal electrode and the grounding electrode. This so-called "leak current" is used to generate a leak alarm signal.

    摘要翻译： 用于检测用于治疗患者组织的流体填充装置中的泄漏的装置包括具有可扩张装置的导管，该可扩张装置围绕导管的远端界定流体储存器。 内部电极与流体储存器内的导电流体电接触。 接地电极位于流体储存器的外部，与患者的组织电接触。 电压被提供给内部电极和接地电极。 在可扩张装置中发生泄漏的情况下，导电流体将接触病人的组织，从而在内部电极和接地电极之间产生电流通路。 这种所谓的“泄漏电流”用于产生泄漏报警信号。

    Heated balloon having rotary fluid impeller
    75.
    发明授权
    Heated balloon having rotary fluid impeller 失效
    加热气球具有旋转流体叶轮

    公开(公告)号：US5954714A

    公开(公告)日：1999-09-21

    申请号：US752501

    申请日：1996-11-20

    申请人： Vahid Saadat ,  John J. McIntyre ,  Gail Stevens

    发明人： Vahid Saadat ,  John J. McIntyre ,  Gail Stevens

    IPC分类号： A61B17/42 ,  A61B17/00 ,  A61B18/00 ,  A61B18/04 ,  A61B18/08 ,  A61F7/12 ,  A61M25/00 ,  A61B17/38

    CPC分类号： A61F7/123 ,  A61B18/08 ,  A61B18/00 ,  A61B2017/00557 ,  A61B2017/4216 ,  A61B2018/00559

    摘要： Apparatus for thermal coagulation having an improved circulation assembly and heating assembly. The apparatus includes a balloon catheter secured to and in fluid communication with a handle for inserting the apparatus into a human uterus. A distensible bladder is secured to the distal end of the catheter and encloses a heating assembly having a tubular core configured with a spiral groove which retains a heating filament. An impeller having at least two blades is positioned distal of the heating assembly and includes a cable having a distal end secured to the impeller. The impeller cable is partially disposed in the handle, in the elongate tubular member and in the core of the heating element, such that axial rotation of said cable rotates the blades of said impeller. During use of the apparatus, the distensible bladder is inflated with a fluid to a desired pressure and rotation of the impeller blades is initiated. The inflation fluid within the distensible bladder is heated to a desired temperature, which is maintained for a desired time interval. The inflation fluid within the distensible bladder is allowed to cool and rotation of the impeller blades is terminated. Thereafter, the inflation fluid is removed from the balloon catheter to deflate the distensible bladder.

    摘要翻译： 具有改进的循环组件和加热组件的热凝固装置。 该装置包括固定在手柄上且与手柄流体连通的气囊导管，用于将装置插入人子宫。 可扩张的囊被固定到导管的远端，并且包围一个加热组件，该加热组件具有一个管状芯体，其配置有一个保持加热细丝的螺旋槽。 具有至少两个叶片的叶轮位于加热组件的远侧，并且包括具有固定到叶轮的远端的电缆。 叶轮电缆部分地设置在手柄中，在细长管状构件中和加热元件的芯部中，使得所述电缆的轴向旋转使所述叶轮的叶片旋转。 在使用该装置的过程中，可膨胀囊被流体充气至期望的压力，并且叶轮叶片的旋转开始。 可膨胀膀胱内的充气流体被加热到期望的温度，其保持期望的时间间隔。 允许扩张囊内的充气流体冷却并终止叶轮的旋转。 此后，将膨胀流体从球囊导管中移出以使可膨胀囊膨胀。

    Methods for preventing tissue migration
    77.
    发明授权
    Methods for preventing tissue migration 有权

    公开(公告)号：US10335131B2

    公开(公告)日：2019-07-02

    申请号：US11877386

    申请日：2007-10-23

    申请人： Vahid Saadat ,  Ruey-Feng Peh ,  Edmund A. Tam ,  Chris A. Rothe

    发明人： Vahid Saadat ,  Ruey-Feng Peh ,  Edmund A. Tam ,  Chris A. Rothe

    IPC分类号： A61B1/00 ,  A61B17/02 ,  A61B1/313 ,  A61B17/34 ,  A61B1/005 ,  A61B6/00 ,  A61B8/08

    摘要： A method of inhibiting tissue migration comprises positioning an open area of a hood against or adjacent to a tissue region. The method also comprises displacing an opaque fluid with a transparent fluid from the open area. The method includes engaging a portion of the tissue region within the open area via an end effector advanced through the open area and which grasps onto the portion. The end effector includes a tapered section, tapered along its entire length, through which a lumen extends. The tapered section includes threads extending from a surface of the tapered section in a direction orthogonal to the longitudinal axis. The tissue region is pierced while displacing the opaque fluid with the transparent fluid through the distal opening of the hood and while maintaining engagement of the portion of the tissue region such that distal movement of the tissue is inhibited.

    Delivery Of Biological Compounds To Ischemic And/Or Infarcted Tissue
    79.
    发明申请
    Delivery Of Biological Compounds To Ischemic And/Or Infarcted Tissue 审中-公开
    向缺血和/或梗塞组织递送生物化合物

    公开(公告)号：US20160227989A1

    公开(公告)日：2016-08-11

    申请号：US15130416

    申请日：2016-04-15

    申请人： Vahid Saadat ,  Sekhar S. Rao

    发明人： Vahid Saadat ,  Sekhar S. Rao

    IPC分类号： A61B1/00 ,  A61B1/015 ,  A61B1/05 ,  A61B5/00

    CPC分类号： A61B1/00165 ,  A61B1/00089 ,  A61B1/00096 ,  A61B1/00147 ,  A61B1/015 ,  A61B1/05 ,  A61B1/12 ,  A61B5/0084 ,  A61B5/6882 ,  A61B5/7282 ,  A61M25/0074 ,  A61M25/0082 ,  A61M25/0084

    摘要： The delivery of biological compounds to ischemic and/or infarcted tissue are described herein where such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for performing any number of procedures on the tissue for identifying, locating, and/or accessing ischemic and/or infarcted tissue.

    摘要翻译： 在本文中描述了将生物化合物递送至缺血和/或梗死组织，其中这样的系统可以包括展开导管和可展开成扩展构型的附接成像罩。 在使用中，成像罩被放置在通常填充有不透明体液如血液的体腔中的待成像组织区域附近或邻近。 半透明或透明的液体（例如盐水）可被泵送到成像罩中，直到流体移动任何血液，从而留下通过展开导管中的成像元件成像的组织的清晰区域。 此外，任何数量的治疗工具也可以通过展开导管并进入成像罩，以在组织上执行任何数量的程序，用于识别，定位和/或获取缺血和/或梗死组织。