公开(公告)号：US08070823B2

公开(公告)日：2011-12-06

申请号：US13073963

申请日：2011-03-28

申请人： Franz W. Kellar ,  Harold Lloyd Crowder

发明人： Franz W. Kellar ,  Harold Lloyd Crowder

IPC分类号： A61F2/30 ,  A61F2/28 ,  A61F2/32 ,  A61F2/44

CPC分类号： A61F2/30767 ,  A61F2/32 ,  A61F2/34 ,  A61F2/36 ,  A61F2/3603 ,  A61F2/367 ,  A61F2/3676 ,  A61F2/38 ,  A61F2/4425 ,  A61F2002/30014 ,  A61F2002/30112 ,  A61F2002/30153 ,  A61F2002/30322 ,  A61F2002/30324 ,  A61F2002/30571 ,  A61F2002/30589 ,  A61F2002/3066 ,  A61F2002/30673 ,  A61F2002/30675 ,  A61F2002/30682 ,  A61F2002/30878 ,  A61F2002/3092 ,  A61F2002/30922 ,  A61F2002/30929 ,  A61F2002/30934 ,  A61F2002/30937 ,  A61F2002/30955 ,  A61F2002/30968 ,  A61F2002/30981 ,  A61F2002/3446 ,  A61F2002/3495 ,  A61F2002/3611 ,  A61F2002/3895 ,  A61F2002/443 ,  A61F2230/0004 ,  A61F2230/0019 ,  A61F2250/0018 ,  A61F2250/0026 ,  A61F2250/0036 ,  A61F2310/00011 ,  A61F2310/00179 ,  A61F2310/00239 ,  A61F2310/0058 ,  C23C30/00

摘要： A prosthetic joint includes: (a) first member having a balanced centroidal axis, and comprising a rigid material and a concave interior defining a cup surface, the cup surface including: (i) a cantilevered first flange defining a wear-resistant protruding first contact rim, the first flange being asymmetric relative to the balanced centroidal axis; and (ii) a cantilevered second flange defining a wear-resistant protruding second contact rim; (b) a second member comprising a rigid material with a wear-resistant, convex contact surface; (c) where the first and second contact rims bear against the contact surface of the second member, to transfer loads between the first and second members, while allowing pivoting motion therebetween; and (d) wherein the flanges are shaped and sized so as to deform elastically and permit the first and second contact rims to conform in an irregular shape to the contact surface, when the joint is under load.

摘要翻译： 假体关节包括：（a）第一构件具有平衡的重心轴线，并且包括限定杯表面的刚性材料和凹形内部，所述杯表面包括：（i）悬臂式第一凸缘，其限定耐磨突出的第一接触 边缘，第一凸缘相对于平衡重心轴线是不对称的; 和（ii）限定耐磨突出的第二接触边缘的悬臂式第二凸缘; （b）第二构件，其包括具有耐磨凸起接触表面的刚性材料; （c）第一和第二接触边缘抵靠第二构件的接触表面，以在第一和第二构件之间传递载荷，同时允许它们之间的枢转运动; 和（d）其中所述凸缘的形状和尺寸设计成使得弹性变形，并且当所述接头处于负载状态时，允许所述第一和第二接触边缘与所述接触表面一致。

公开(公告)号：US08062378B2

公开(公告)日：2011-11-22

申请号：US12054678

申请日：2008-03-25

申请人： Matthew V. Fonte

发明人： Matthew V. Fonte

IPC分类号： A61F2/36

CPC分类号： A61F2/30942 ,  A61F2/30742 ,  A61F2/30767 ,  A61F2/30771 ,  A61F2/3094 ,  A61F2/36 ,  A61F2/3662 ,  A61F2/367 ,  A61F2/3676 ,  A61F2/468 ,  A61F2002/30014 ,  A61F2002/30018 ,  A61F2002/30019 ,  A61F2002/30039 ,  A61F2002/30092 ,  A61F2002/30093 ,  A61F2002/30153 ,  A61F2002/30579 ,  A61F2002/30604 ,  A61F2002/30616 ,  A61F2002/30682 ,  A61F2002/30685 ,  A61F2002/30769 ,  A61F2002/30891 ,  A61F2002/30892 ,  A61F2002/30909 ,  A61F2002/30955 ,  A61F2002/30968 ,  A61F2002/3611 ,  A61F2002/3625 ,  A61F2002/365 ,  A61F2002/3664 ,  A61F2210/0014 ,  A61F2210/0019 ,  A61F2230/0019 ,  A61F2250/0018 ,  A61F2250/0029 ,  A61F2250/0042 ,  A61F2250/0048 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00407 ,  A61F2310/00598 ,  A61F2310/00796 ,  A61F2310/0097

摘要： A method for arthroplasty includes using a self-locking prosthesis that has a member structured to transfer a load produced by the weight of a patient to a bone. An expandable bone-locking portion that is integral to the member includes a shape-memory material and expands to produce a locking force. A portion of the bone is removed to form an aperture in the bone. The bone-locking portion is inserted into the aperture, and a temperature increase causes a change from a contracted state to an expanded state resulting in expansion of the bone-locking portion so as to contact the inner surface. The expanding is sufficient to create a locking force at the junction between the inner surface and the bone-locking portion of the prosthesis and the majority of the locking force is applied at or above the metaphysis. The length/width ration of the prosthesis may be less than or equal to 5. The resulting reconstructed long-bone may have improved primary and long-term stability.

摘要翻译： 关节成形术的方法包括使用自锁假体，其具有构造成将由患者的重量产生的负载转移到骨骼的构件。 与构件成一体的可扩张骨锁定部分包括形状记忆材料并膨胀以产生锁定力。 去除骨的一部分以在骨中形成孔。 骨锁定部分插入孔中，并且温度升高导致从收缩状态向扩张状态的变化，导致骨锁定部分膨胀以与内表面接触。 膨胀足以在假体的内表面和骨锁定部分之间的接合处产生锁定力，并且大部分锁定力施加在干at端处或上方。 假体的长度/宽度比例可以小于或等于5.所得重构的长骨可具有改善的初级和长期稳定性。

公开(公告)号：US08034115B2

公开(公告)日：2011-10-11

申请号：US12425041

申请日：2009-04-16

申请人： Mark A. Reiley

发明人： Mark A. Reiley

IPC分类号： A61F2/42

CPC分类号： A61F2/4606 ,  A61B17/15 ,  A61B17/1617 ,  A61B17/1682 ,  A61B17/1717 ,  A61B17/1775 ,  A61B17/8625 ,  A61F2/30767 ,  A61F2/4202 ,  A61F2002/30064 ,  A61F2002/30332 ,  A61F2002/30578 ,  A61F2002/30604 ,  A61F2002/30616 ,  A61F2002/30622 ,  A61F2002/30785 ,  A61F2002/30878 ,  A61F2002/30948 ,  A61F2002/30968 ,  A61F2002/4205 ,  A61F2002/4207 ,  A61F2002/421 ,  A61F2002/4631 ,  A61F2220/0033 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00131 ,  A61F2310/00179 ,  A61F2310/00329 ,  A61F2310/00395 ,  A61F2310/00796 ,  A61F2310/0097

摘要： A total ankle replacement system, novel surgical method for total ankle replacement, and novel surgical tools for performing the surgical method are described. The total ankle replacement system includes the calcaneus in fixation of a lower prosthesis body, thereby significantly increasing the amount of bone available for fixation of the lower prosthesis body and allowing the lower prosthesis body to be anchored with screws. The total ankle replacement system further includes a long tibial stem which can also be anchored into the tibia with, for example, screws, nails, anchors, or some other means of attachment. The novel surgical arthroscopic method allows introduction of ankle prostheses into the ankle joint through an exposure in the tibial tubercle. Various novel surgical instruments, such as a telescoping articulating reamer and a talo-calcaneal jig, which facilitate the novel surgical method, are also described.

摘要翻译： 描述了全踝置换系统，全踝置换的新型手术方法，以及用于执行手术方法的新型手术工具。 总踝关节置换系统包括在下修复体的固定中的跟骨，从而显着增加可用于固定下假体体的骨量，并允许下部假肢体用螺钉锚定。 总的踝关节置换系统还包括长的胫骨杆，其也可以用例如螺钉，钉子，锚固件或一些其它附接装置锚固到胫骨中。 该新型外科关节镜方法允许通过胫骨结节中的暴露将踝假体引入踝关节。 还描述了便于新颖手术方法的各种新型外科器械，例如伸缩关节铰刀和talo-calcaneal夹具。

公开(公告)号：US20110206828A1

公开(公告)日：2011-08-25

申请号：US13046192

申请日：2011-03-11

申请人： James Jeng Liu ,  Janet L. Krevolin

发明人： James Jeng Liu ,  Janet L. Krevolin

IPC分类号： B05D3/02

CPC分类号： A61F2/28 ,  A61F2/3094 ,  A61F2/4465 ,  A61F2002/30062 ,  A61F2002/3092 ,  A61F2002/30968 ,  A61F2002/4495 ,  A61F2210/0004 ,  A61F2310/00329 ,  A61L24/0036 ,  A61L24/02 ,  A61L27/10 ,  A61L27/56 ,  A61L2400/18 ,  A61L2430/02 ,  C03C4/0014 ,  C03C11/00

摘要： A resorbable tissue scaffold fabricated from bioactive glass fiber forms a rigid three-dimensional porous matrix having a bioactive composition. Porosity in the form of interconnected pore space is provided by the space between the bioactive glass fiber in the porous matrix. Strength of the bioresorbable matrix is provided by bioactive glass that fuses and bonds the bioactive glass fiber into the rigid three-dimensional matrix. The resorbable tissue scaffold supports tissue in-growth to provide osteoconductivity as a resorbable tissue scaffold, used for the repair of damaged and/or diseased bone tissue.

公开(公告)号：US07998523B2

公开(公告)日：2011-08-16

申请号：US12092545

申请日：2006-10-12

申请人： Reto Lerf ,  Hans Schmotzer ,  Stephan Siegmann

发明人： Reto Lerf ,  Hans Schmotzer ,  Stephan Siegmann

IPC分类号： A61L33/00

CPC分类号： A61L27/56 ,  A61F2/30767 ,  A61F2002/3092 ,  A61F2002/30968 ,  A61L27/306 ,  Y10T428/12549

摘要： The invention relates to open-pore biocompatible surface layers for implants, which layers are arranged over virgin surfaces of the implants, wherein pores of the open-pore surface layers are connected to form coherent pore networks and the surface layers have a specific internal surface area of ≧0.06 μm/μm2, preferably ≧0.035 μm/μm2 and especially ≧0.025 μm/μm2, measured by image analysis as a 2D-boundary line per unit of surface area in a metallographic microsection at 100× magnification. The invention further relates to methods of producing such surface layers, to implants coated therewith and to possible uses of the surface layers.

摘要翻译： 本发明涉及用于植入物的开孔生物相容性表面层，其中层布置在植入物的原始表面上，其中开放孔表面层的孔连接以形成粘连孔网络，并且表面层具有特定的内表面积 通过在100倍放大倍率下的金相显微切片中的每单位表面积的2D边界线的图像分析测定的≥0.06μm/μm2，优选≥0.035μm/μm2，特别是≥0.025μm/μm2。 本发明还涉及生产这种表面层的方法，其中涂覆的植入物和表面层的可能用途。

公开(公告)号：US07972648B2

公开(公告)日：2011-07-05

申请号：US11977351

申请日：2007-10-24

申请人： Bruce Berckmans, III ,  Ross W. Towse ,  Robert L. Mayfield

发明人： Bruce Berckmans, III ,  Ross W. Towse ,  Robert L. Mayfield

IPC分类号： B05D3/12 ,  B05D5/02 ,  A61K6/00 ,  A61L27/32

CPC分类号： A61C8/0015 ,  A61B17/86 ,  A61C8/0012 ,  A61C8/0013 ,  A61C8/0022 ,  A61C13/00 ,  A61F2/30767 ,  A61F2002/3084 ,  A61F2002/30968 ,  A61F2310/00796 ,  A61L27/04 ,  A61L27/10 ,  A61L27/425 ,  A61L27/50 ,  A61L2400/12 ,  A61L2430/02 ,  A61L2430/12 ,  B82Y30/00 ,  C23C22/02 ,  C23C24/08 ,  C23C26/00 ,  C23C30/00 ,  C23F1/00

摘要： A method of forming an implant to be implanted into living bone is disclosed. The method comprises the act of roughening at least a portion of the implant surface to produce a microscale roughened surface. The method further comprises forming a nanoscale roughened surface on the microscale roughened surface. The method further comprises the act of depositing discrete nanoparticles on the nanoscale roughened surface though a one-step process of exposing the roughened surface to a solution including the nanoparticles. The nanoparticles comprise a material having a property that promotes osseointegration.

摘要翻译： 公开了一种形成待植入活骨的植入物的方法。 该方法包括使植入物表面的至少一部分粗糙化以产生微观粗糙表面的作用。 该方法还包括在微观粗糙表面上形成纳米尺度的粗糙表面。 该方法还包括通过将粗糙化表面暴露于包括纳米颗粒的溶液的一步法将纳米尺度粗糙化表面上的离散纳米颗粒沉积的行为。 纳米颗粒包含具有促进骨整合性质的材料。

公开(公告)号：US20110144752A1

公开(公告)日：2011-06-16

申请号：US13058905

申请日：2009-08-07

申请人： Scott F. Defelice ,  Anthony Decarmine

发明人： Scott F. Defelice ,  Anthony Decarmine

IPC分类号： A61F2/28 ,  C08G16/00 ,  A61L27/46

CPC分类号： A61F2/30771 ,  A61F2/28 ,  A61F2/30942 ,  A61F2002/30774 ,  A61F2002/30784 ,  A61F2002/30838 ,  A61F2002/3092 ,  A61F2002/3093 ,  A61F2002/30948 ,  A61F2002/30952 ,  A61F2002/30962 ,  A61F2002/30968 ,  A61F2002/3097 ,  A61F2240/002 ,  A61L27/165 ,  A61L27/54 ,  A61L27/56 ,  A61L2300/602 ,  A61L2430/02 ,  B29C64/153 ,  B29K2071/00 ,  B29L2031/7532 ,  B33Y80/00 ,  C08L29/12

摘要： The present invention relates to customized implants for bone replacement that are prepared from poly(ether ketone ketone) or PEKK, and to a computer-based imaging and rapid prototyping (RP)-based manufacturing method for the design and manufacture of these customized implants. The PEKK customized implants made using rapid prototyping demonstrate biomechanical properties similar (if not identical) to that of natural bone even when prepared without the use of processing aids such as carbon black and aluminum powder.

摘要翻译： 本发明涉及由聚（醚酮酮）或PEKK制备的用于骨置换的定制植入物，以及用于设计和制造这些定制植入物的基于计算机的成像和快速成型（RP）制造方法。 使用快速成型制备的PEKK定制植入物即使在不使用加工助剂如炭黑和铝粉的情况下制备时也能显示生物力学性质与天然骨骼的生物力学性质相似（如果不相同）。

公开(公告)号：US20110132974A1

公开(公告)日：2011-06-09

申请号：US13027697

申请日：2011-02-15

申请人： Steven J. Charlebois ,  Leslie N. Gilbertson ,  Michael E. Hawkins ,  Dana J. Medlin ,  H. Ravindranath Shetty ,  Steven A. Zawadzki

发明人： Steven J. Charlebois ,  Leslie N. Gilbertson ,  Michael E. Hawkins ,  Dana J. Medlin ,  H. Ravindranath Shetty ,  Steven A. Zawadzki

IPC分类号： B23K31/02

CPC分类号： B23P23/00 ,  A61F2/30767 ,  A61F2/30907 ,  A61F2/3094 ,  A61F2/3859 ,  A61F2002/30787 ,  A61F2002/30967 ,  A61F2002/30968 ,  A61F2002/30978 ,  A61F2002/3401 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00407 ,  A61F2310/00544 ,  A61L27/04 ,  A61L27/30 ,  A61L27/56 ,  B22F7/004 ,  B22F7/064 ,  C23C26/00 ,  Y10T29/49861

摘要： A method for attaching a porous metal layer to a dense metal substrate, wherein the method is particularly useful in forming orthopedic implants such as femoral knee components, femoral hip components, and/or acetabular cups. The method, in one embodiment thereof, comprises providing a solid metal substrate; providing a porous metal structure; contouring a surface of the porous metal structure; placing the porous structure against the substrate such that the contoured surface of the porous metal structure is disposed against the substrate, thereby forming an assembly; applying heat and pressure to the assembly in conjunction with thermal expansion of the substrate in order to metallurgically bond the porous structure and the substrate; and removing mass from the substrate after the porous structure is bonded to the substrate, thereby finish processing the assembly.

摘要翻译： 一种将多孔金属层附着到致密金属基底上的方法，其中该方法特别可用于形成诸如股骨膝部件，股骨髋部件和/或髋臼杯之类的矫形植入物。 该方法在其一个实施方案中包括提供固体金属基底; 提供多孔金属结构; 轮廓化多孔金属结构的表面; 将所述多孔结构放置在所述基底上，使得所述多孔金属结构的轮廓表面抵靠所述基底设置，由此形成组件; 将热和压力结合基片的热膨胀施加到组件，以便冶金地结合多孔结构和基底; 并且在将多孔结构结合到基板上之后从基板去除质量，从而完成组装。

公开(公告)号：US20110125277A1

公开(公告)日：2011-05-26

申请号：US12991361

申请日：2009-05-06

申请人： Mats Nygren ,  Changming Xu ,  Leif Ryd ,  Katarina Flodström ,  Nina Bake

发明人： Mats Nygren ,  Changming Xu ,  Leif Ryd ,  Katarina Flodström ,  Nina Bake

IPC分类号： A61F2/38

CPC分类号： A61F2/30 ,  A61F2/30756 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/38 ,  A61F2/3877 ,  A61F2002/30004 ,  A61F2002/30014 ,  A61F2002/30016 ,  A61F2002/30922 ,  A61F2002/30968 ,  A61F2002/30971 ,  A61F2250/0014 ,  A61F2250/0018 ,  A61F2250/0019 ,  A61F2310/00011 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00179 ,  A61F2310/00293 ,  A61L27/46

摘要： A medical implant for application in an articulating surface of a joint, comprising a plate-shaped structure having a first surface and a second surface facing mutually opposite directions, the first surface comprising a first biocompatible metal, metal alloy or ceramic and being devised to form a wear resistant articulate surface configured to face the articulating part of the joint; and the second surface comprising a bioactive ceramic or bioactive glass incorporated into a second metal, metal alloy or ceramic and being devised to form a bone contacting surface configured to face bone structure in the joint; wherein: the first surface and the second surface are adhered by means of a sintered material structure. Possibly the second surface is a sintered mixture having a homogenous microstructure comprising the bioactive ceramic or bioactive glass and the second metal, metal alloy or ceramic.

摘要翻译： 一种应用于关节的关节表面的医用植入物，包括具有第一表面和面向相互相反方向的第二表面的板状结构，所述第一表面包括第一生物相容性金属，金属合金或陶瓷，并被设计成形成 耐磨的铰接表面，其构造成面向接头的铰接部分; 并且所述第二表面包括结合到第二金属，金属合金或陶瓷中的生物活性陶瓷或生物活性玻璃，并被设计成形成构造为面对所述关节中的骨结构的骨接触表面; 其中：第一表面和第二表面通过烧结材料结构粘合。 第二表面可能是具有包含生物活性陶瓷或生物活性玻璃和第二金属，金属合金或陶瓷的均匀微结构的烧结混合物。

公开(公告)号：US20110106272A1

公开(公告)日：2011-05-05

申请号：US12832394

申请日：2010-07-08

申请人： JAMES JENG LIU

发明人： JAMES JENG LIU

IPC分类号： A61F2/28 ,  B29C31/00

CPC分类号： A61F2/4465 ,  A61F2/02 ,  A61F2/28 ,  A61F2/30734 ,  A61F2/3094 ,  A61F2/44 ,  A61F2002/30062 ,  A61F2002/3092 ,  A61F2002/30968 ,  A61F2002/4495 ,  A61F2210/0004 ,  A61F2310/00329 ,  A61L27/10 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L2400/18 ,  A61L2430/02 ,  A61L2430/38 ,  C03C4/0014 ,  C03C10/0009 ,  C03C11/00 ,  C03C13/006 ,  C03C2204/00 ,  C03C2213/02 ,  Y10T428/249928

摘要： A resorbable tissue scaffold fabricated from bioactive glass fiber forms a rigid three-dimensional porous matrix having a bioactive composition. Porosity in the form of interconnected pore space is provided by the space between the bioactive glass fiber in the porous matrix. Strength of the bioresorbable matrix is provided by bioactive glass that fuses and bonds the bioactive glass fiber into the rigid three-dimensional matrix. The resorbable tissue scaffold supports tissue in-growth to provide osteoconductivity as a resorbable tissue scaffold, used for the repair of damaged and/or diseased bone tissue.