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公开(公告)号：US08876903B2
公开(公告)日：2014-11-04
申请号：US13151343
申请日：2011-06-02
申请人： Anke Burger-Kentischer , Ina Hogk , Doris Finkelmeier , Heike Walles , Steffen Rupp , Michaela Kaufmann
发明人： Anke Burger-Kentischer , Ina Hogk , Doris Finkelmeier , Heike Walles , Steffen Rupp , Michaela Kaufmann
CPC分类号： G01N33/5058 , A61F2/105 , G01N2333/035
摘要： The invention relates to a multi-layered biological in vitro tissue containing: dermis layer, containing a collagen biomatrix with fibroblasts embedded therein and epidermis layer, containing epithelial cells. It is provided that latently virally infected neuronal cells are integrated at least into the dermis layer.
摘要翻译： 本发明涉及包含真皮层的多层生物体外组织，其含有嵌入其中的成纤维细胞的胶原生物基质和含有上皮细胞的表皮层。 提供了潜在的病毒感染的神经细胞至少整合到真皮层中。
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公开(公告)号：US20110300530A1
公开(公告)日：2011-12-08
申请号：US13151343
申请日：2011-06-02
申请人： Anke BURGER-KENTISCHER , Ina Hogk , Doris Finkelmeier , Heike Walles , Steffen Rupp , Michaela Kaufmann
发明人： Anke BURGER-KENTISCHER , Ina Hogk , Doris Finkelmeier , Heike Walles , Steffen Rupp , Michaela Kaufmann
IPC分类号： C12Q1/70
CPC分类号： G01N33/5058 , A61F2/105 , G01N2333/035
摘要： The invention relates to a multi-layered biological in vitro tissue containing: dermis layer, containing a collagen biomatrix with fibroblasts embedded therein and epidermis layer, containing epithelial cells. It is provided that latently virally infected neuronal cells are integrated at least into the dermis layer.
摘要翻译： 本发明涉及包含真皮层的多层生物体外组织，其含有嵌入其中的成纤维细胞的胶原生物基质和含有上皮细胞的表皮层。 提供了潜在的病毒感染的神经细胞至少整合到真皮层中。
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公开(公告)号：US20080293079A1
公开(公告)日：2008-11-27
申请号：US12066136
申请日：2006-09-27
申请人： Nicole Hauser , Steffen Rupp , Achim Weber , Guenter Tovar , Ekkehard Hiller , Kirsten Borchers
发明人： Nicole Hauser , Steffen Rupp , Achim Weber , Guenter Tovar , Ekkehard Hiller , Kirsten Borchers
IPC分类号： G01N33/569 , C12M1/34 , B05D1/00
CPC分类号： G01N33/56961 , G01N33/54346 , G01N2333/40
摘要： The present invention concerns means and methods of detection of Candida and Candida-related fungal cells in clinical material by means of protein biochips.
摘要翻译： 本发明涉及通过蛋白质生物芯片检测临床材料中念珠菌和假丝酵母相关真菌细胞的方法和方法。
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公开(公告)号：US20100216239A1
公开(公告)日：2010-08-26
申请号：US12302667
申请日：2007-05-30
申请人： Xin Xiong , Heike Mertsching , Steffen Rupp , Herwig Brunner
发明人： Xin Xiong , Heike Mertsching , Steffen Rupp , Herwig Brunner
CPC分类号： C12N5/0068 , A61L27/24 , A61L27/38 , C08L89/06 , C12N2533/54
摘要： The present invention concerns isolated collagen, the method for its production, and isolation of the collagen from collagen-containing tissues, as well as the use of the isolated collagen in a biomatrix as an in vitro test system, tissue replacement or organ replacement.
摘要翻译： 本发明涉及分离的胶原蛋白，其生产方法和从胶原蛋白组织中分离胶原蛋白，以及将生物基质中分离的胶原蛋白作为体外试验系统，组织置换或器官置换。
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公开(公告)号：US20050048570A1
公开(公告)日：2005-03-03
申请号：US10500425
申请日：2002-12-27
申请人： Achim Weber , Thomas Schiestel , Gunter Tovar , Herwig Brunner , Steffen Rupp , Nicole Hauser
发明人： Achim Weber , Thomas Schiestel , Gunter Tovar , Herwig Brunner , Steffen Rupp , Nicole Hauser
IPC分类号： G01N27/62 , B01J19/00 , C12N1/00 , C12N15/09 , C12Q1/04 , C12Q1/68 , C40B60/14 , G01N21/27 , G01N21/33 , G01N21/64 , G01N33/53 , G01N33/543 , G01N33/545 , G01N33/547 , G01N33/552 , G01N33/553 , G01N37/00 , C12M1/34
CPC分类号： G01N33/54346 , B01J19/0046 , B01J2219/00382 , B01J2219/00427 , B01J2219/00466 , B01J2219/00527 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/0063 , B01J2219/00635 , B01J2219/00637 , B01J2219/00644 , B01J2219/00648 , B01J2219/00659 , B82Y30/00 , C40B60/14 , G01N33/54393
摘要： The present invention relates to functional elements that comprise microstructures containing biofunctionalized nanoparticles arranged on a carrier, a method for the production of these functional elements and the use thereof.
摘要翻译： 本发明涉及包含布置在载体上的生物官能化纳米微结构的功能元件，这些功能元件的制造方法及其用途。
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公开(公告)号：US08013121B2
公开(公告)日：2011-09-06
申请号：US12302667
申请日：2007-05-30
申请人： Xin Xiong , Heike Mertsching , Steffen Rupp , Herwig Brunner
发明人： Xin Xiong , Heike Mertsching , Steffen Rupp , Herwig Brunner
IPC分类号： C07K1/14
CPC分类号： C12N5/0068 , A61L27/24 , A61L27/38 , C08L89/06 , C12N2533/54
摘要： The present invention concerns isolated collagen, the method for its production, and isolation of the collagen from collagen-containing tissues, as well as the use of the isolated collagen in a biomatrix as an in vitro test system, tissue replacement or organ replacement.
摘要翻译： 本发明涉及分离的胶原蛋白，其生产方法和从胶原蛋白组织中分离胶原蛋白，以及将生物基质中分离的胶原蛋白作为体外试验系统，组织置换或器官置换。
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公开(公告)号：US07220574B2
公开(公告)日：2007-05-22
申请号：US10275933
申请日：2001-05-10
申请人： Steffen Rupp , Franz-Josef Johannes , Kai Sohn
发明人： Steffen Rupp , Franz-Josef Johannes , Kai Sohn
CPC分类号： C12Q1/6895 , C12Q2600/158 , Y10S977/792
摘要： The present invention relates to biochips, in particular nucleotide chips, which contain hyphen-specific proteins coding nucleotides, protein chips which contain hyphen-specific proteins, and antibody chips which contain antibodies directed against these hyphen-specific proteins, diagnostic compositions which contain these nucleotide, protein, or antibody chips, processes for the location and identification of substances which are therapeutically effective against diseases caused by types of Candida and processes for the diagnosis of a disease caused by Candida.
摘要翻译： 本发明涉及包含编码核苷酸的连字号特异性蛋白质，含有连字号特异性蛋白质的蛋白质芯片和含有针对这些连字号特异性蛋白质的抗体的抗体芯片的生物芯片，特别是核苷酸芯片，含有这些核苷酸的诊断组合物 ，蛋白质或抗体片段，用于定位和鉴定对由念珠菌种类引起的疾病具有治疗有效性的物质的方法和用于诊断由念珠菌引起的疾病的过程。
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公开(公告)号：US06303302B1
公开(公告)日：2001-10-16
申请号：US09189462
申请日：1998-11-10
申请人： Steffen Rupp , Laura Robertson , Eric F. Summers , Peter Hecht , Radclyffe Roberts , Hiten Madhani , Cora Ann Styles , Hsiu-Jung Lo , Amir Sherman , Brian Cali , Gerald L. Fink
发明人： Steffen Rupp , Laura Robertson , Eric F. Summers , Peter Hecht , Radclyffe Roberts , Hiten Madhani , Cora Ann Styles , Hsiu-Jung Lo , Amir Sherman , Brian Cali , Gerald L. Fink
IPC分类号： C12Q168
CPC分类号： C12Q1/18 , G01N2500/10
摘要： Disclosed herein are methods for regulating fungal gene expression, and reagents for carrying out those methods.
摘要翻译： 本文公开了调节真菌基因表达的方法和用于实施这些方法的试剂。
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公开(公告)号：US20090156426A1
公开(公告)日：2009-06-18
申请号：US11568162
申请日：2005-04-09
申请人： Thomas Schiestel , Steffen Rupp
发明人： Thomas Schiestel , Steffen Rupp
CPC分类号： G01N33/54353 , B01D67/0088 , B01D67/0093 , B01D69/122 , B01J19/0046 , B01J2219/00286 , B01J2219/00317 , B01J2219/00466 , B01J2219/00576 , B01J2219/00641 , B01J2219/00648 , B01J2219/0072 , B01J2219/00722 , B01J2219/00725
摘要： The present invention relates to functionalized porous carriers which comprise a material having at least one porous surface, nanoparticles having molecule-specific recognition sites being present in the pores of the material surface, and to a process for producing functionalized porous carriers. The invention further relates to functional elements produced using the functionalized carriers, such as microtiter plates, microarrays and flow devices, and also to uses of the functionalized carriers and functional elements.
摘要翻译： 本发明涉及包含具有至少一个多孔表面的材料的功能化多孔载体，具有分子特异性识别位点的纳米颗粒存在于材料表面的孔中，以及制备官能化多孔载体的方法。 本发明还涉及使用官能化载体产生的功能元件，例如微量滴定板，微阵列和流动装置，以及功能化载体和功能元件的用途。
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公开(公告)号：US06599705B2
公开(公告)日：2003-07-29
申请号：US09863040
申请日：2001-05-22
申请人： Steffen Rupp , Laura Robertson , Eric F. Summers , Peter Hecht , Radclyffe Roberts , Hiten Madhani , Cora Ann Styles , Hsiu-Jung Lo , Amir Sherman , Brian Cali , Gerald R. Fink
发明人： Steffen Rupp , Laura Robertson , Eric F. Summers , Peter Hecht , Radclyffe Roberts , Hiten Madhani , Cora Ann Styles , Hsiu-Jung Lo , Amir Sherman , Brian Cali , Gerald R. Fink
IPC分类号： C12Q168
CPC分类号： C12Q1/18 , G01N2500/10
摘要： Disclosed herein are methods for regulating fungal gene expression, and reagents for carrying out those methods.
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