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    Hyphae-Specific Cell Wall Proteins Of Candida
    4.
    发明申请
    Hyphae-Specific Cell Wall Proteins Of Candida 审中-公开
    假丝酵母特异性细胞壁蛋白

    公开(公告)号：US20070196378A1

    公开(公告)日：2007-08-23

    申请号：US10593213

    申请日：2005-03-15

    申请人： Henrike Lotz ,  Herwig Brunner ,  Steffen Rupp

    发明人： Henrike Lotz ,  Herwig Brunner ,  Steffen Rupp

    IPC分类号： A61K48/00 ,  C12Q1/68 ,  G01N33/569 ,  C07H21/04 ,  A61K39/395 ,  C12N9/48 ,  C12N1/18 ,  C12N1/16 ,  C12N15/74

    CPC分类号： C07K14/40

    摘要： Nucleic acids that code a cell wall protein required for the hyphal development of Candida; fragments of the nucleic acids; vectors containing the nucleic acids or nucleic acid fragments; host cells containing the vectors; cell wall proteins coded by the nucleic acids; antibodies directed against the proteins; methods for producing the cell wall proteins; methods for characterizing and/or for detecting the hyphal stage of Candida; methods for detecting a Candida infection; methods for identifying substances having a therapeutic effect against diseases caused by Candida; diagnostic and pharmaceutical compositions containing the nucleic acid, nucleic acids fragments, vectors, host cells, proteins and/or antibodies directed against the cell wall protein; kits for conducting in-vitro indentation of the cell wall proteins, and; to the use of the nucleic acids, vectors, proteins or antibodies for diagnosing and treating Candida-caused diseases, i.e., producing diagnostic or pharmaceutical compositions.

    摘要翻译： 编码念珠菌菌丝体发育所需的细胞壁蛋白的核酸; 核酸片段; 含有核酸或核酸片段的载体; 含有载体的宿主细胞; 由核酸编码的细胞壁蛋白; 针对蛋白质的抗体; 生产细胞壁蛋白的方法; 表征和/或检测假丝酵母菌丝阶段的方法; 检测念珠菌感染的方法; 用于鉴定具有针对由念珠菌引起的疾病的治疗效果的物质的方法; 含有针对细胞壁蛋白的核酸，核酸片段，载体，宿主细胞，蛋白质和/或抗体的诊断和药物组合物; 用于进行细胞壁蛋白的体外压痕的试剂盒，和 涉及使用核酸，载体，蛋白质或抗体来诊断和治疗念珠菌引起的疾病，即产生诊断或药物组合物。

    Hyphen-specific factors from Candida albicans
    7.
    发明授权
    Hyphen-specific factors from Candida albicans 有权
    来自白色念珠菌的连翘特异性因子

    公开(公告)号：US07220574B2

    公开(公告)日：2007-05-22

    申请号：US10275933

    申请日：2001-05-10

    申请人： Steffen Rupp ,  Franz-Josef Johannes ,  Kai Sohn

    发明人： Steffen Rupp ,  Franz-Josef Johannes ,  Kai Sohn

    IPC分类号： C12M1/36 ,  C12P19/34 ,  C12Q1/68 ,  C07H21/04 ,  G01N33/48

    CPC分类号： C12Q1/6895 ,  C12Q2600/158 ,  Y10S977/792

    摘要： The present invention relates to biochips, in particular nucleotide chips, which contain hyphen-specific proteins coding nucleotides, protein chips which contain hyphen-specific proteins, and antibody chips which contain antibodies directed against these hyphen-specific proteins, diagnostic compositions which contain these nucleotide, protein, or antibody chips, processes for the location and identification of substances which are therapeutically effective against diseases caused by types of Candida and processes for the diagnosis of a disease caused by Candida.

    摘要翻译： 本发明涉及包含编码核苷酸的连字号特异性蛋白质，含有连字号特异性蛋白质的蛋白质芯片和含有针对这些连字号特异性蛋白质的抗体的抗体芯片的生物芯片，特别是核苷酸芯片，含有这些核苷酸的诊断组合物 ，蛋白质或抗体片段，用于定位和鉴定对由念珠菌种类引起的疾病具有治疗有效性的物质的方法和用于诊断由念珠菌引起的疾病的过程。