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1.
公开(公告)号:US09005987B2
公开(公告)日:2015-04-14
申请号:US12761299
申请日:2010-04-15
申请人: Emil P. Kartalov , Axel Scherer , Clive R. Taylor
发明人: Emil P. Kartalov , Axel Scherer , Clive R. Taylor
CPC分类号: B01L3/502753 , B01L2200/0647 , B01L2300/0645 , B01L2300/0816 , B01L2300/0864
摘要: Described herein are methods for quantitative target detection in a sample through use of microbeads and related devices and systems.
摘要翻译: 本文描述了通过使用微珠和相关装置和系统在样品中进行定量目标检测的方法。
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2.
公开(公告)号:US20100267162A1
公开(公告)日:2010-10-21
申请号:US12761299
申请日:2010-04-15
申请人: Emil P. KARTALOV , Axel Scherer , Clive R. Taylor
发明人: Emil P. KARTALOV , Axel Scherer , Clive R. Taylor
CPC分类号: B01L3/502753 , B01L2200/0647 , B01L2300/0645 , B01L2300/0816 , B01L2300/0864
摘要: Described herein are methods for quantitative target detection in a sample through use of microbeads and related devices and systems.
摘要翻译: 本文描述了通过使用微珠和相关装置和系统在样品中进行定量目标检测的方法。
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公开(公告)号:US08480978B2
公开(公告)日:2013-07-09
申请号:US13206362
申请日:2011-08-09
申请人: Emil P. Kartalov , Axel Scherer , Koichi Sayano
发明人: Emil P. Kartalov , Axel Scherer , Koichi Sayano
CPC分类号: B01L3/502753 , A61M1/3472 , A61M1/3496 , A61M1/3633 , A61M2205/0244 , B01L2300/0645 , B01L2300/0681 , B01L2300/0816 , B01L2300/0864 , B01L2300/087 , B01L2400/0424 , Y10T436/25125 , Y10T436/25375
摘要: A microfluidic fluid separator for separating target components of a fluid by filtration is described. Methods for separating target components of a fluid by filtration and methods for processing blood on a large scale with the microfluidic fluid separator are provided.
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公开(公告)号:US20120085648A1
公开(公告)日:2012-04-12
申请号:US13206362
申请日:2011-08-09
申请人: Emil P. KARTALOV , Axel Scherer , Koichi SAYANO
发明人: Emil P. KARTALOV , Axel Scherer , Koichi SAYANO
CPC分类号: B01L3/502753 , A61M1/3472 , A61M1/3496 , A61M1/3633 , A61M2205/0244 , B01L2300/0645 , B01L2300/0681 , B01L2300/0816 , B01L2300/0864 , B01L2300/087 , B01L2400/0424 , Y10T436/25125 , Y10T436/25375
摘要: A microfluidic fluid separator for separating target components of a fluid by filtration is described. Methods for separating target components of a fluid by filtration and methods for processing blood on a large scale with the microfluidic fluid separator are provided.
摘要翻译: 描述了用于通过过滤分离流体的目标成分的微流体流体分离器。 提供了通过过滤分离流体的目标组分的方法和用微流体分离器大规模处理血液的方法。
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5.
公开(公告)号:US20100267064A1
公开(公告)日:2010-10-21
申请号:US12717402
申请日:2010-03-04
申请人: Emil P. Kartalov , Axel Scherer , Clive Taylor
发明人: Emil P. Kartalov , Axel Scherer , Clive Taylor
CPC分类号: G01N33/5306 , B01L3/502738 , B01L2300/0816 , B01L2300/0864 , B01L2300/088 , B01L2300/0883 , B01L2400/0475
摘要: Described herein is a method for detection of a target in a sample and related devices and systems.
摘要翻译: 这里描述了用于检测样品中的目标物和相关装置和系统的方法。
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公开(公告)号:US08424560B2
公开(公告)日:2013-04-23
申请号:US12636086
申请日:2009-12-11
申请人: Emil P. Kartalov , John Liu , Axel Scherer , Clive Taylor
发明人: Emil P. Kartalov , John Liu , Axel Scherer , Clive Taylor
IPC分类号: F16K31/365 , F16K31/36 , F15C3/04 , F15C1/06
CPC分类号: G05D7/0694 , F16K99/0001 , F16K99/0015 , F16K99/0026 , F16K99/0057 , F16K2099/008 , Y10T137/0318 , Y10T137/218 , Y10T137/2202 , Y10T137/2224 , Y10T137/7795 , Y10T137/7796
摘要: Multi-valve autoregulatory microfluidic devices and methods are described. The described devices and methods offer improved performance and new means of tuning autoregulatory effects in microfluidic devices.
摘要翻译: 描述了多瓣膜自动调节微流体装置和方法。 所描述的装置和方法提供改进的性能和调整微流体装置中的自动调节效应的新手段。
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7.
公开(公告)号:US08361738B2
公开(公告)日:2013-01-29
申请号:US12717402
申请日:2010-03-04
申请人: Emil P. Kartalov , Axel Scherer , Clive Taylor
发明人: Emil P. Kartalov , Axel Scherer , Clive Taylor
IPC分类号: G01N33/00
CPC分类号: G01N33/5306 , B01L3/502738 , B01L2300/0816 , B01L2300/0864 , B01L2300/088 , B01L2300/0883 , B01L2400/0475
摘要: Described herein is a method for detection of a target in a sample and related devices and systems.
摘要翻译: 这里描述了用于检测样品中的目标物和相关装置和系统的方法。
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公开(公告)号:US09316586B2
公开(公告)日:2016-04-19
申请号:US13417121
申请日:2012-03-09
CPC分类号: G01N21/645 , B01L3/50851 , B01L3/50853 , B01L7/52 , B01L7/54 , B01L2200/147 , B01L2300/0829 , B01L2300/0838 , B01L2300/12 , B01L2300/168 , B01L2300/1822 , B01L2300/1827 , B01L2300/185 , B01L2300/1861
摘要: This invention provides a system for performing PCR, and real time PCR in particular, with great speed and specificity. The system employs a heat block containing a liquid composition to rapidly transfer heat to and from reaction vessels. The system makes use of the reflective properties of the liquid metal to reflect signal from the PCR into the vessel and out the top. In this way, the signal can be measured by an optical assembly in real time without removing the vessels from the heat block.
摘要翻译: 本发明提供了一种用于特别快速和特异性地进行PCR和实时PCR的系统。 该系统采用含有液体组合物的热块来快速地将热量传递到反应容器和从其返回。 该系统利用液态金属的反射特性,将来自PCR的信号反射入容器并排出顶部。 以这种方式,可以通过光学组件实时地测量信号,而不从容器中取出容器。
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公开(公告)号:US08670471B2
公开(公告)日:2014-03-11
申请号:US12711111
申请日:2010-02-23
申请人: Seheon Kim , Axel Scherer
发明人: Seheon Kim , Axel Scherer
IPC分类号: H01S3/10
CPC分类号: H01S5/183 , B82Y20/00 , H01L31/0352 , H01L31/035281 , H01L33/0045 , H01L2933/0083 , H01S5/041 , H01S5/105 , H01S5/18319 , H01S5/18327 , H01S5/18352 , H01S5/34 , H01S5/3412 , Y02E10/50
摘要: Photonic crystal cavities and related devices and methods are described. The described cavities can be used as lasers, photovoltaic sources, and single photon sources. The cavities can be both optically and electrically pumped. A fabrication process of the cavities is also described.
摘要翻译: 描述了光子晶体腔及相关装置和方法。 所描述的空腔可以用作激光器,光电源和单个光子源。 空腔可以光学和电气泵送。 还描述了空腔的制造工艺。
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公开(公告)号:US08535512B2
公开(公告)日:2013-09-17
申请号:US13248994
申请日:2011-09-29
申请人: Sameer Walavalkar , Axel Scherer , Thomas A. Tombrello , Aditya Rajagopal , Andrew P. Homyk , Erika Garcia
发明人: Sameer Walavalkar , Axel Scherer , Thomas A. Tombrello , Aditya Rajagopal , Andrew P. Homyk , Erika Garcia
CPC分类号: G01N27/447 , B82Y30/00 , C12Q1/6869 , G01N33/48721 , C12Q2563/116 , C12Q2565/631
摘要: Methods and devices for sequencing nucleic acids are disclosed herein. Devices are also provided herein for measuring DNA with nano-pores sized to allow DNA to pass through the nano-pore. The capacitance can be measured for the DNA molecule passing through the nano-pore. The capacitance measurements can be correlated to determine the sequence of base pairs passing through the nano-pore to sequence the DNA.
摘要翻译: 本文公开了用于测序核酸的方法和装置。 本文还提供了用于测量具有大小允许DNA穿过纳米孔的纳米孔的DNA的装置。 可以测量通过纳米孔的DNA分子的电容。 电容测量可以相关,以确定通过纳米孔的碱基对序列来对DNA进行排序。
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