摘要:
Fluorescent latices, well suited for a wide variety of analytical techniques, comprise polymer particles having at least one hydrophobic fluorochrome encapsulated therein, notably at least one condensed polyaromatic compound or derivative thereof, or a tetraphenylporphine and/or organometallic complex thereof, and have a detection threshold for fluorescence which is less than or equal to 10.sup.-12 mol of particles per liter of latex.
摘要:
A fluorescent latex with particles containing at least one encapsulated hydrophobic fluorochrome A (acceptor) and at least one encapsulated hydrophobic fluorochrome D (donor), wherein A is different from D and exposure to light radiation enables the emission from fluorochrome D to excite fluorochrome A, and a method for producing said latex and its use as a marker, particularly a biological marker, are also disclosed.
摘要:
Latices of monodisperse magnetizable microspheres contain a hydrophobic polymer matrix and magnetizable fillers. The microspheres have a calibrated particle-size distribution and a size of around 0.1-5 micrometers, and the polymer matrix, produced by a dispersion polymerization method, includes polymer chains derived from at least one vinyl monomer. The latices are useful in biology, in particular, for diagnostic and affinity chromatography methods.
摘要:
The invention relates to a glycosylated particle of latex or of inorganic oxide, exhibiting functional radicals at the surface. At least a proportion of said functional radicals is joined to a glycosyl residue. The particles preferably consist either of polymers obtained by polymerization of ethylenically unsaturated monomers or of silica. The invention finds an application as a detection agent in biology.
摘要:
The invention relates to a latex microsphere consisting of polymers obtained by polymerization of ethylenically unsaturated monomers, having functional groups at the surface, and remarkable in that biotinyl residues are grafted onto at least part of the said groups, via a divalent chain. It also relates to the avidin- or streptavidin-biotin complex obtained with the aid of the said microsphere and to the use of the microsphere or of the complex as agent for diagnosis, for biological assay or for immunological assay.
摘要:
The invention relates to a liquid pharmaceutical composition comprising a pegylated IFN-β (PEG-IFN-β), an excipient, a surfactant and a buffer wherein said excipient is a polyol, wherein said surfactant is a non-ionic surfactant and wherein said buffer is a sodium acetate buffer.
摘要:
The invention relates to growth hormone (GH) formulations having sustained-release properties, in particular human growth hormone (hGH) and methods for their preparation. The growth hormone formulations can be manufactured without denaturing of the protein and can conveniently be administrated to the person in need thereof by using a conventional syringe via a needle having a small diameter.
摘要:
The present invention relates to a water-redispersible powder based on film-forming polymers which are substantially water-insoluble and which are prepared by aqueous emulsion polymerization of monomers containing ethylenic unsaturation with a "core/shell" structure comprising a hydrophobic core based on a polymer exhibiting a Tg (glass transition temperature) of between -30.degree. and +25.degree. C., preferably between -10.degree. and +20.degree. C., and a hydrophilic shell based on a polymer exhibiting a Tg higher than +55.degree. C., preferably higher than +90.degree. C., characterized in that the shell is bonded to the core by covalent bonds resulting from the reaction of an agent for grafting the shell onto the ethylenic unsaturations remaining in the core, and is substantially insoluble in an alkaline medium.
摘要:
Polymeric compositions well suited for conversion into electroconductive shaped articles, e.g., films, comprise at least one convertible polymer (Pm) and at least one amphiphilic organic compound (B) which comprises a charge transfer complex or a radical ion salt having the formula (I): D.sub.d A.sub.a Z.sub.z, in which D is an electron donor; A is an electron acceptor; Z is a doping agent which itself can be a non-amphiphilic electron donor or electron acceptor, with the proviso that at least one of D and A is amphiphilic and contains at least one saturated or unsaturated hydrocarbon substituent having at least 10 carbon atoms; d is a number equal to or greater than 0; a is a number equal to or greater than 0; and z is a number equal to or greater than 0, with the further proviso that at least one of the symbols d and a is a number greater than 0.
摘要:
The invention relates to a microlithographic process for producing circuits using organic, conductive films sensitive to electromagnetic radiation and to charged particles.This process for producing electricity conducting zones on a substrate consists of depositing on said substrate a coating of an electricity conducting, organic compound, such as alkyl pyridinium-tetracyanoquinodimethane and then irradiating certain locations (2,3) of the coating by means of charged particles and/or electromagnetic radiation, so that the irradiated locations become insulating and that on the organic compound coating the electricity conducting zones (1) are directly formed at the desired locations.