Quarternary Ammonium Compound, Process for Producing the Same, Therapeutic Agent for Cerebrovascular Disorder, and Therapeutic Agent for Heart Disease
    1.
    发明申请
    Quarternary Ammonium Compound, Process for Producing the Same, Therapeutic Agent for Cerebrovascular Disorder, and Therapeutic Agent for Heart Disease 失效
    四季铵化合物,其制备方法,脑血管障碍治疗剂和心脏病治疗剂

    公开(公告)号:US20080269345A1

    公开(公告)日:2008-10-30

    申请号:US10594545

    申请日:2005-03-29

    摘要: A quaternary ammonium compound of the present invention is a quaternary ammonium compound represented by general formula (I) or (I′) (wherein, A represents a linear alkyl group having 1 to 4 carbon atoms, a branched alkyl group having 2 to 4 carbon atoms, a linear alkyl group having 1 to 4 carbon atoms and a hydroxyl group, or a branched alkyl group having 2 to 4 carbon atoms and a hydroxyl group, R1 to R3 may be the same or different and represent a linear or branched alkyl group having 1 to 12 carbon atoms, one of R4 to R8 represents CO2− or SO3−, while no more than three of the remaining R4 to R8 represent a group selected from the group consisting of a hydroxyl group and an alkoxy group having 1 to 4 carbon atoms, and other R4 to R8 represent a hydrogen atom, one of R′4 to R′8 represents CO2H or SO3H, no more than three of the remaining R′4 to R′8 represent a group selected from a protected hydroxyl group and an alkoxy group having 1 to 4 carbon atoms, while other R′4 to R′8 represent a hydrogen atom, and X− represents an anion capable of forming a salt with a quaternary ammonium group).

    摘要翻译: 本发明的季铵化合物是通式(I)或(I')表示的季铵化合物(其中,A表示碳原子数1〜4的直链烷基,碳原子数2〜4的支链烷基 原子,具有1至4个碳原子和羟基的直链烷基或具有2至4个碳原子和羟基的支链烷基,R 1至R 3, SUB>可以相同或不同,表示具有1至12个碳原子的直链或支链烷基,R 4至R 8中的一个表示CO 2 - 或SO 3 - ,而不超过三个剩余的R 4至R 8表示选自羟基和碳原子数1〜4的烷氧基的基团,以及其它R 4〜R 8, SUB>表示氢原子,R'4'至R'8之一表示CO 2 H或SO 3

    Quaternary ammonium compound, process for producing the same, therapeutic agent for cerebrovascular disorder, and therapeutic agent for heart disease
    2.
    发明授权
    Quaternary ammonium compound, process for producing the same, therapeutic agent for cerebrovascular disorder, and therapeutic agent for heart disease 失效
    第四季铵化合物,其制备方法,脑血管障碍治疗剂和心脏病治疗剂

    公开(公告)号:US07687546B2

    公开(公告)日:2010-03-30

    申请号:US10594545

    申请日:2005-03-29

    IPC分类号: A01N33/12 A61K31/14

    摘要: A quaternary ammonium compound of the present invention is a quaternary ammonium compound represented by general formula (I) or (I′) (wherein, A represents a linear alkyl group having 1 to 4 carbon atoms, a branched alkyl group having 2 to 4 carbon atoms, a linear alkyl group having 1 to 4 carbon atoms and a hydroxyl group, or a branched alkyl group having 2 to 4 carbon atoms and a hydroxyl group, R1 to R3 may be the same or different and represent a linear or branched alkyl group having 1 to 12 carbon atoms, one of R4 to R8 represents CO2− or SO3−, while no more than three of the remaining R4 to R8 represent a group selected from the group consisting of a hydroxyl group and an alkoxy group having 1 to 4 carbon atoms, and other R4 to R8 represent a hydrogen atom, one of R′4 to R′8 represents CO2H or SO3H, no more than three of the remaining R′4 to R′8 represent a group selected from a protected hydroxyl group and an alkoxy group having 1 to 4 carbon atoms, while other R′4 to R′8 represent a hydrogen atom, and X− represents an anion capable of forming a salt with a quaternary ammonium group).

    摘要翻译: 本发明的季铵化合物是由通式(I)或(I')(表示的季铵化合物,其中,A表示具有1至4个碳原子,具有2-4个碳支链烷基的直链烷基 原子,碳原子数为1〜4的直链烷基和羟基的基团,或具有2至4个碳原子和羟基基团的支链烷基,R1至R3可以相同或不同,表示直链或支链的烷基 具有1至12个碳原子,R4中的一个来R8表示CO 2 - 或SO 3 - ,而不超过三个剩余的R 4至R 8中的表示选自羟基的基团和具有1至4的烷氧基中的基团 碳原子,并且另一个R 4至R 8表示氢原子,R'4中的一个来表示R 18 CO 2 H或SO 3 H,不超过三个剩余的R'4至R'8的表示从受保护的羟基中的基团 和具有1至4个碳原子的烷氧基,而其它R 4至R'8表示氢原子,X - 表示能够形成与季铵基团的盐)的阴离子。

    Method for separating and recovering dimethyl terephthalate and ethylene glycol from polyester waste
    5.
    发明授权
    Method for separating and recovering dimethyl terephthalate and ethylene glycol from polyester waste 有权
    从聚酯废料中分离回收对苯二甲酸二甲酯和乙二醇的方法

    公开(公告)号:US06706843B1

    公开(公告)日:2004-03-16

    申请号:US10111010

    申请日:2002-04-19

    IPC分类号: C08J1104

    摘要: For separation and recovery of dimethyl terephthalate (DMT) and ethyiene glycol (EG) from polyester waste containing foreign materials, the polyester waste is treated in EG containing a polyester depolymerization catalyst, a solid foreign material fraction floated on the surface of the resultant reaction solution is removed and the residual solid foreign material fraction is removed from the remaining solution fraction. The remaining solution fraction is distilled and concentrated and the distilled EG is recovered. A transesterification reaction catalyst and methanol are mixed into the distillation residue. The resultant reaction mixture is recrystallized and subjected to centrifugal separation to separate the reaction mixture into the DMT cake and a mixture solution, and then the cake is distilled whereby high-purity DMT is recovered. The residual mixture solution is subjected to distillation treatment for recovery of the methanol, and the distillation residue is distilled to recover EG.

    摘要翻译: 为了从含有异物的聚酯废物中分离和回收对苯二甲酸二甲酯(DMT)和乙二醇(EG),聚酯废物在含有聚酯解聚催化剂的EG中处理,固体异物部分漂浮在所得反应溶液的表面 并从剩余的溶液馏分中除去残留的固体异物馏分。 将剩余的溶液馏分蒸馏并浓缩并回收蒸馏的EG。 将酯交换反应催化剂和甲醇混合到蒸馏残余物中。 将所得反应混合物重结晶并进行离心分离,将反应混合物分离成DMT滤饼和混合溶液,然后将滤饼蒸馏,从而回收高纯度DMT。 将残留的混合溶液进行蒸馏处理以回收甲醇,并蒸馏残余物以回收EG。

    Rotating electric machine usable in radioactive environment
    6.
    发明授权
    Rotating electric machine usable in radioactive environment 有权
    旋转电机可用于放射性环境

    公开(公告)号:US6093988A

    公开(公告)日:2000-07-25

    申请号:US187484

    申请日:1998-11-06

    CPC分类号: H02K5/04 H02K5/1732

    摘要: The invention relates to a rotating electric machine including (a) a rotor having a rotating shaft; (b) a bearing for supporting the rotating shaft; (c) a radiation resistant grease applied to the bearing; and (d) a shield layer for shielding the grease from radiation. The shield layer is made of lead and surrounds the bearing. The shield layer includes (1) a first cylindrical shield member that is positioned to cover the bearing, such that the bearing is shielded from a first radiation that is in a direction substantially perpendicular to an axis of the rotating shaft, and (2) second and third disk shield members that are positioned to interpose therebetween the bearing in a direction along the axis of the rotating shaft, such that the bearing is shielded from a second radiation that is in a direction substantially along the axis of the rotating shaft. Thus, the rotor of this rotating electric machine is stably supported in the bearing for a long time even under a highly radioactive environment. That is, the rotating electric machine can be rotated stably for a long time.

    摘要翻译: 本发明涉及一种旋转电机,其包括:(a)具有旋转轴的转子; (b)用于支撑旋转轴的轴承; (c)施加到轴承的防辐射油脂; 和(d)用于屏蔽防止辐射的润滑脂的屏蔽层。 屏蔽层由铅制成并围绕轴承。 屏蔽层包括(1)第一圆柱形屏蔽构件,其被定位成覆盖轴承,使得轴承与基本上垂直于旋转轴的轴线的方向上的第一辐射屏蔽,以及(2)第二 以及第三盘屏蔽构件,其定位成沿着所述旋转轴的轴线的方向介于所述轴承之间,使得所述轴承与基本上沿着所述旋转轴的轴线的方向的第二辐射屏蔽。 因此,即使在高放射性环境下,该旋转电机的转子也能够长期稳定地支撑在轴承中。 也就是说,旋转电机可以长时间稳定地旋转。