Method of bonding microstructured substrates
    1.
    发明申请
    Method of bonding microstructured substrates 有权
    粘结微结构基材的方法

    公开(公告)号:US20060124230A1

    公开(公告)日:2006-06-15

    申请号:US10560405

    申请日:2004-06-14

    IPC分类号: B44C1/165

    摘要: Gluing process for micro-structured substrates. The invention is applicable particularly to the fabrication of micro-fluidic components. In order to glue a micro-structured substrate (2) having upper coplanar plane areas (6) and recesses between them, a grid (10) is placed above the substrate, the grid is coated with a glue (12), using a tool (16) that presses on the grid and locally brings it into contact with the areas, so as to deposit a film (20) of glue droplets on them, and the grid is removed. Furthermore, the upper coplanar plane areas (6) are treated before the film of glue droplets is deposited, this treatment being designed to adapt wettability of these areas to the glue.

    摘要翻译: 微结构基材的胶合工艺。 本发明特别适用于微流体组件的制造。 为了胶合具有上共面平面区域(6)和它们之间的凹槽的微结构的衬底(2),栅格(10)放置在衬底上方,栅格用胶水(12)涂覆,使用工具 (16),其压在栅格上并且局部地使其与区域接触,以便在其上沉积胶滴(20),栅格被去除。 此外,在沉积胶滴的膜之前处理上共面平面区域(6),该处理被设计成使这些区域的润湿性适应于胶水。

    Method And Device For Division Of A Biological Sample By Magnetic Effect
    5.
    发明申请
    Method And Device For Division Of A Biological Sample By Magnetic Effect 有权
    通过磁效应分解生物样品的方法和装置

    公开(公告)号:US20070199901A1

    公开(公告)日:2007-08-30

    申请号:US10581357

    申请日:2004-12-13

    IPC分类号: C02F1/48

    摘要: A method for dividing an analyte present in a solution and that is fixed on magnetic particles, and devices to be used in the method and systems for implementing the method. The method includes sedimentation of the magnetic particles together with separation into a plurality of residues. One implementation: forms at least a residue of magnetic particles in a first receptacle; and displaces the at least the residues towards a plurality of second receptacles, preferably by relative translation of a magnetic system. The second receptacle is connected to the first receptacle through a fluid channel.

    摘要翻译: 用于分离存在于溶液中并固定在磁性颗粒上的分析物的方法以及用于实施该方法的方法和系统中使用的装置。 该方法包括将磁性颗粒沉淀并分离成多个残余物。 一个实施方案:在第一容器中形成至少一个磁性颗粒残留物; 并且将至少残留物移向多个第二容器,优选通过磁性系统的相对平移。 第二容器通过流体通道连接到第一容器。

    Optical microstructure positioning system
    6.
    发明授权
    Optical microstructure positioning system 失效
    光学微结构定位系统

    公开(公告)号:US06320999B1

    公开(公告)日:2001-11-20

    申请号:US09156912

    申请日:1998-09-18

    IPC分类号: G02B626

    摘要: A positioning system for an optical microstructure (64) in a devise (6) operating under the action of a control means includes a flexible element (63) supporting the optical microstructure and connected to the device. The orientation of the flexible element with respect to the device can be varied under the action of control means in order to put the optical microstructure (64) into at least one determined position. The flexible element is immobilized with respect to the device in order to hold the optical microstructure (64) in the determined position when the control means no longer act.

    摘要翻译: 用于在控制装置的作用下操作的装置(6)中的光学微结构(64)的定位系统包括支撑光学微结构并连接到该装置的柔性元件(63)。 可以在控制装置的作用下改变柔性元件相对于装置的取向,以便将光学微结构(64)放入至少一个确定的位置。 柔性元件相对于装置被固定,以便当控制装置不再起作用时将光学微结构(64)保持在确定的位置。

    Enhancing surface-generated fluorescence signal emitted by a sample
    10.
    发明授权
    Enhancing surface-generated fluorescence signal emitted by a sample 失效
    增强样品发出的表面产生的荧光信号

    公开(公告)号:US06893876B2

    公开(公告)日:2005-05-17

    申请号:US10129948

    申请日:2000-12-01

    CPC分类号: G01N21/6452

    摘要: A device and process for the amplification of fluorescence emitted by an areal sample. The device includes a support transmitting all or part of a fluorescence signal and configured to support the areal sample and a thin layer interposed between the support and the areal sample. The thin layer has a refractive index greater than the refractive index of the support and than the refractive index of a medium flooding the areal sample during a fluorescence measurement. The thickness of the thin layer is chosen so that the thin layer transmits all or part of the fluorescence signal which is measured after passing through the support.

    摘要翻译: 用于扩增由面状样品发射的荧光的装置和方法。 该装置包括透射全部或部分荧光信号并被配置为支撑面状样品的支撑体和介于载体和面状样品之间的薄层。 薄层的折射率大于支撑体的折射率,而不是在荧光测量期间填充面状样品的介质的折射率。 选择薄层的厚度,使得薄层透过在通过载体之后测量的全部或部分荧光信号。