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1.发明申请NOVEL FORMULATIONS OF FAT-SOLUBLE ACTIVE INGREDIENTS WITH HIGH BIOAVAILABILITY 审中-公开具有高生物利用性的脂溶性活性成分的新配方公开(公告)号：US20120039964A1
公开(公告)日：2012-02-16
申请号：US13282708
申请日：2011-10-27
申请人： Markus BECK , Hansjoerg Grass , Bruno H. Leuenberger , Markus Nowotny , Christian Schäfer , Karl Manfred Voelker
发明人： Markus BECK , Hansjoerg Grass , Bruno H. Leuenberger , Markus Nowotny , Christian Schäfer , Karl Manfred Voelker
IPC分类号： A61K9/107 , A61K31/573 , A61P3/02 , A61K31/12 , A61K31/11 , A61K31/015 , A61K31/01
CPC分类号： A61K9/2081 , A23K20/174 , A23K20/179 , A23L5/44 , A23L33/155 , A23V2002/00 , A61K8/0241 , A61K8/31 , A61K9/2013 , A61K9/2018 , A61K9/2059 , A61K31/01 , A61K31/047 , A61K2800/52 , A61K2800/56 , A61Q19/00
摘要： The present invention relates to formulations of a pharmacological effective fat-soluble active ingredient with a high bioavailability of said fat-soluble active ingredient as well as to their manufacture and use as dietary supplement, food, feed, personal care product and/or pharmaceutical. Such formulations are those which when dissolved, dispersed or diluted in/with water have an extinction E1/1 at a wavelength in the range of from 200 to 800 nm, preferably in the range of from 250 to 600 nm, more preferably in the range of from 250 to 500 nm, more preferably in the range of from 370 to 485 nm, of ≧380, preferably of ≧600, most preferably ≧900. In preferred embodiments of the formulations of the present invention such formulations show an extrusion loss of fat-soluble active ingredient of ≦30% when pressed to tablets.
摘要翻译： 本发明涉及具有所述脂溶性活性成分的高生物利用度的药理学有效的脂溶性活性成分以及作为膳食补充剂，食品，饲料，个人护理产品和/或药物的制造和用途的制剂。 这样的配方是当在水中溶解，分散或稀释时在200至800nm范围内，优选在250至600nm范围内的波长具有消光E1 / 1，更优选在该范围内 250〜500nm，更优选370〜485nm，≥380，优选≥600，最优选≥900。 在本发明制剂的优选实施方案中，这些制剂显示当压制成片剂时，脂溶性活性成分的挤出损失为30％。
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公开(公告)号：US20100136177A1
公开(公告)日：2010-06-03
申请号：US12526148
申请日：2008-02-04
IPC分类号： A23L1/275 , A23L1/303 , A23L1/0522 , A23L1/0524 , A23L1/053 , A23L1/0534
CPC分类号： A23L2/58 , A23L2/395 , A23L33/105 , A23L33/155 , A23P10/40 , A23V2002/00 , A23V2200/30 , A23V2250/211 , A23V2250/5118 , A23V2250/5114 , A23V2200/254
摘要： Process for the manufacture of a powder containing one or more carotenoids, powder obtainable by said process and food composition containing said powder.
摘要翻译： 用于制造含有一种或多种类胡萝卜素的粉末的方法，所述方法可获得的粉末和含有所述粉末的食品组合物。
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公开(公告)号：US10463061B2
公开(公告)日：2019-11-05
申请号：US11666843
申请日：2005-11-18
申请人： Markus Beck , Bruno H. Leuenberger , Christina Rebernig-Staiger , Christian Schaefer , Gerhard Wagner
发明人： Markus Beck , Bruno H. Leuenberger , Christina Rebernig-Staiger , Christian Schaefer , Gerhard Wagner
IPC分类号： A23K50/80 , A23L2/52 , A23L2/58 , C08B37/00 , A23K20/179 , A23K20/147 , A23K20/163 , A23K50/75 , A23L29/20 , A23L29/25 , A23L5/43 , A23L33/10
摘要： The present invention relates to compositions containing (fat-soluble) active ingredients and/or colorants in a matrix based on modified plant gums, i.e. plant gums that have been submitted to hydrolysis to degrade either the protein portion and/or where appropriate, the polysaccharide, and to a process for preparing these compositions as well as to modified plant gums, whose protein part is hydrolyzed up to a degree of about 30%, preferably to a degree of from about 0.05 to about 30%, and/or whose polysaccharide part is hydrolyzed up to a degree of about 50%, a process for the manufacture thereof and such modified plant gums themselves. The present invention further relates to the use of the compositions of this invention for the enrichment, fortification and/or for the coloration of food, beverages, animal feed, cosmetics and pharmaceutical compositions and to such food, beverages, animal feed, cosmetics and pharmaceutical compositions themselves.
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公开(公告)号：US20090010861A1
公开(公告)日：2009-01-08
申请号：US11666843
申请日：2005-11-18
申请人： Markus Beck , Bruno H. Leuenberger , Christina Rebernig-Staiger , Christian Schaefer , Gerhard Wagner
发明人： Markus Beck , Bruno H. Leuenberger , Christina Rebernig-Staiger , Christian Schaefer , Gerhard Wagner
IPC分类号： A61K8/97 , A61K47/42 , A61K31/015 , A61K31/355 , A61K31/047 , A61K31/07 , A61K47/46
CPC分类号： A23K50/80 , A23K20/147 , A23K20/163 , A23K20/179 , A23K50/75 , A23L2/52 , A23L2/58 , A23L5/43 , A23L29/20 , A23L29/25 , A23L33/10 , C08B37/0087 , Y02A40/818
摘要： The present invention relates to compositions containing (fat-soluble) active ingredients and/or colorants in a matrix based on modified plant gums, i.e. plant gums that have been submitted to hydrolysis to degrade either the protein portion and/or where appropriate, the polysaccharide, and to a process for preparing these compositions as well as to modified plant gums, whose protein part is hydrolysed up to a degree of about 30%, preferably to a degree of from about 0.05 to about 30%, and/or whose polysaccharide part is hydrolysed up to a degree of about 50%, a process for the manufacture thereof and such modified plant gums themselves. The present invention further relates to the use of the compositions of this invention for the enrichment, fortification and/or for the coloration of food, beverages, animal feed, cosmetics and pharmaceutical compositions and to such food, beverages, animal feed, cosmetics and pharmaceutical compositions themselves.
摘要翻译： 本发明涉及在基于改性植物胶的基质中含有（脂溶性）活性成分和/或着色剂的组合物，即植物胶已经被水解以降解蛋白质部分和/或适当时降解多糖 ，以及制备这些组合物的方法以及改性植物胶，其蛋白质部分被水解至约30％，优选至约0.05至约30％的程度，和/或其多糖部分 被水解达约50％的程度，其制备方法和这种改性植物胶本身。 本发明还涉及本发明的组合物用于食品，饮料，动物饲料，化妆品和药物组合物的富集，强化和/或着色以及这种食品，饮料，动物饲料，化妆品和药物 组合本身。
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公开(公告)号：US20090258954A1
公开(公告)日：2009-10-15
申请号：US12095927
申请日：2006-12-08
申请人： Markus Beck , Navagnana S. Hettiarachchy , Bruno H. Leuenberger , IIankovan Paraman , Christian Schaefer , Gerhard Wagner
发明人： Markus Beck , Navagnana S. Hettiarachchy , Bruno H. Leuenberger , IIankovan Paraman , Christian Schaefer , Gerhard Wagner
CPC分类号： C07K14/415 , A23J1/12 , A23J3/14 , A23J3/34 , A23K20/174 , A23K20/179 , A23K40/00 , A23L5/44 , A23L7/115 , A23L7/198 , A23L33/155 , A23P10/40 , A61K47/42 , C12P21/06 , C12Y304/00
摘要： (Modified) rice endosperm protein is used as novel protective hydrocolloid for active ingredients, especially fat-soluble active ingredients and/or colorants. Included are compositions comprising (modified) rice endosperm protein and at least one active ingredient and to their manufacture, as well as to the (modified) rice endosperm protein itself and its manufacture. These compositions are used for the enrichment, fortification and/or coloration of food, beverages, animal feed, personal care or pharmaceutical compositions, and to food, beverages, animal feed, personal care and pharmaceutical compositions containing such a (modified) rice endosperm protein and such a composition, respectively.
摘要翻译： （改良型）水稻胚乳蛋白用作活性成分，特别是脂溶性活性成分和/或着色剂的新型保护性水胶体。 包括包含（修饰的）水稻胚乳蛋白质和至少一种活性成分及其制备的组合物以及（修饰的）水稻胚乳蛋白质本身及其制造的组合物。 这些组合物用于食品，饮料，动物饲料，个人护理或药物组合物的富集，强化和/或着色，以及含有这种（修饰的）水稻胚乳蛋白质的食品，饮料，动物饲料，个人护理和药物组合物 和这样的组合物。
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公开(公告)号：US20120149782A1
公开(公告)日：2012-06-14
申请号：US13326352
申请日：2011-12-15
IPC分类号： A23L1/053 , A23L1/275 , A23L1/0522 , A61K47/42 , A61K8/73
CPC分类号： A23L1/2753 , A23D7/0053 , A23K20/158 , A23K20/163 , A23K20/174 , A23K20/179 , A23L2/52 , A23L2/58 , A23L5/44 , A23L29/25 , A23V2002/00 , A61K8/732 , A61K8/97 , A61K2800/42 , A61Q1/06 , A61Q5/02 , A61Q5/12 , A61Q19/00 , A61Q19/10 , C08B37/0087 , C08K5/005 , C08K5/01 , C08L5/00 , A23V2200/222 , A23V2200/044 , A23V2250/5022 , A23V2250/211 , A23V2250/5118 , A23V2250/5114
摘要： Compositions containing modified gum acacia, less than 40% oil and carotenoids, where the gum acacia has been subjected to a heat-treatment at a temperature between 100° C. and 115° C. for 1 to 38 hours. These compositions allow preparation of emulsions having a very high color intensity and color stability and useful for the enrichment, fortification and/or coloration of food beverages, animal feed, cosmetics or pharmaceutical compositions.
摘要翻译： 含有改性的阿拉伯胶的组合物，少于40％的油和类胡萝卜素，其中阿拉伯胶已经在100℃和115℃之间的温度下进行1至38小时的热处理。 这些组合物允许制备具有非常高的颜色强度和颜色稳定性并且可用于食品饮料，动物饲料，化妆品或药物组合物的富集，强化和/或着色的乳液。
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7.发明申请公开(公告)号：US20110081330A1
公开(公告)日：2011-04-07
申请号：US12995836
申请日：2009-06-03
IPC分类号： A61K31/015 , A61K31/01 , A61K31/045 , A61K31/225 , A61K31/122 , A61K31/12 , A61K8/31 , A61K8/34 , A61K8/35 , A61K8/37 , A61K38/43 , A61K31/355 , A61K8/66 , A61K8/49 , A23L1/0522 , A23L2/52 , A23L2/58 , A23L1/275 , A23L1/30
CPC分类号： A23L2/52 , A23K20/158 , A23K20/174 , A23K20/179 , A23K50/75 , A23K50/80 , A23L5/44 , A23L29/25 , A23L29/35 , A23L33/105 , A23L33/155 , A23V2002/00 , A23V2250/5056 , A23V2200/044
摘要： The present invention relates to compositions containing plant gums and one or more fat-soluble active ingredients, wherein the composition comprises less than 40 weight-% oil, based on the total composition in dry matter. These compositions can be used for the enrichment, fortification and/or coloration of food beverages, animal feed, cosmetics or pharmaceutical compositions. The present invention also refers to the preparation of such compositions. The present invention furthermore refers to a process for the manufacture of a beverage by mixing the compositions with ingredients of beverages. The present invention also refers to beverages obtainable by this process.
摘要翻译： 本发明涉及含有植物胶和一种或多种脂溶性活性成分的组合物，其中所述组合物包含小于40重量％的油，基于干物质的总组成。 这些组合物可用于食品饮料，动物饲料，化妆品或药物组合物的富集，强化和/或着色。 本发明还涉及这种组合物的制备。 本发明还涉及通过将组合物与饮料成分混合来制造饮料的方法。 本发明还涉及可通过该方法获得的饮料。
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公开(公告)号：US20090214647A1
公开(公告)日：2009-08-27
申请号：US11920555
申请日：2006-05-18
CPC分类号： A23C19/0323 , A23C9/1234 , A23L2/52 , A23L13/74 , A23L33/12 , A23L33/135 , A23L33/40 , A23P10/25 , A23P10/30 , A23P10/35 , A23V2002/00 , A61K35/744 , A61K35/745 , A61K35/747 , C12N11/10 , A23V2200/224 , A23V2200/3204 , A23V2200/202 , A23V2250/1886 , A23V2250/161
摘要： The present invention describes a process for the manufacture of a solid composition comprising a microorganism, which process comprises a first step of blending and/or compacting the microorganism with a salt of a medium or long-chain fatty acid to prepare a powderous mixture or compacted granulate, and a second step of providing said powderous mixture or compacted granulate with a coating. The microorganisms are preferably probiotics. The invention also relates to the solid composition obtained by said process and to its use in food.
摘要翻译： 本发明描述了一种制备包含微生物的固体组合物的方法，该方法包括将微生物与中等或长链脂肪酸的盐共混和/或压实以制备粉状混合物或压实的第一步骤 并且第二步是用涂层提供所述粉末混合物或压实颗粒。 微生物优选为益生菌。 本发明还涉及通过所述方法获得的固体组合物及其在食品中的用途。
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公开(公告)号：US20080241320A1
公开(公告)日：2008-10-02
申请号：US11729981
申请日：2007-03-30
CPC分类号： A23J3/346 , A23J1/125 , A23J3/14 , A23K20/147 , A23L2/66 , A23L5/43 , A23L7/152 , A23L33/15 , A23L33/155 , A23L33/18 , A23P10/30 , A23V2002/00 , C07K14/415 , A23V2200/30 , A23V2200/224 , A23V2250/5482 , A23V2250/712 , A23V2250/211
摘要： Partially deamidated rice endosperm protein or rice endosperm protein which is partially conjugated with mono-, di-, oligo- or polysaccharides is used as novel protective hydrocolloid for fat-soluble active ingredients and/or fat-soluble colorants. The present invention further includes compositions comprising that rice endosperm protein and at least one fat-soluble active ingredient/colorant, as well as their manufacture, that rice endosperm protein itself and its manufacture. These compositions are used for the enrichment, fortification and/or coloration of food, beverages, animal feed, personal care or pharmaceutical compositions. The present invention is directed to theses uses and to food, beverages, animal feed, personal care and pharmaceutical compositions containing such a rice endosperm protein and such a composition, respectively.
摘要翻译： 与单糖，二糖，多糖或多糖部分结合的部分脱酰胺水稻胚乳蛋白或水稻胚乳蛋白被用作脂溶性活性成分和/或脂溶性着色剂的新型保护性水胶体。 本发明还包括包含水稻胚乳蛋白质和至少一种脂溶性活性成分/着色剂的组合物，以及它们的制造，即水稻胚乳蛋白质本身及其制造。 这些组合物用于食品，饮料，动物饲料，个人护理或药物组合物的富集，强化和/或着色。 本发明涉及这些用途以及分别含有这种水稻胚乳蛋白质的食品，饮料，动物饲料，个人护理和药物组合物。
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公开(公告)号：US09332777B2
公开(公告)日：2016-05-10
申请号：US13326352
申请日：2011-12-15
IPC分类号： A61K36/48 , A23L1/275 , A23D7/005 , A23K1/16 , A23L1/053 , A23L2/52 , A23L2/58 , A61K8/73 , A61K8/97 , A61Q19/10 , C08B37/00 , C08K5/00 , C08K5/01 , C08L5/00 , A61Q1/06 , A61Q5/02 , A61Q5/12 , A61Q19/00
CPC分类号： A23L1/2753 , A23D7/0053 , A23K20/158 , A23K20/163 , A23K20/174 , A23K20/179 , A23L2/52 , A23L2/58 , A23L5/44 , A23L29/25 , A23V2002/00 , A61K8/732 , A61K8/97 , A61K2800/42 , A61Q1/06 , A61Q5/02 , A61Q5/12 , A61Q19/00 , A61Q19/10 , C08B37/0087 , C08K5/005 , C08K5/01 , C08L5/00 , A23V2200/222 , A23V2200/044 , A23V2250/5022 , A23V2250/211 , A23V2250/5118 , A23V2250/5114
摘要： Compositions containing modified gum acacia, less than 40% oil and carotenoids, where the gum acacia has been subjected to a heat-treatment at a temperature between 100° C. and 115° C. for 1 to 38 hours. These compositions allow preparation of emulsions having a very high color intensity and color stability and useful for the enrichment, fortification and/or coloration of food beverages, animal feed, cosmetics or pharmaceutical compositions.
摘要翻译： 含有改性的阿拉伯胶的组合物，少于40％的油和类胡萝卜素，其中阿拉伯胶已经在100℃和115℃之间的温度下进行1至38小时的热处理。 这些组合物允许制备具有非常高的颜色强度和颜色稳定性并且可用于食品饮料，动物饲料，化妆品或药物组合物的富集，强化和/或着色的乳液。
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