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16 条记录 (耗时 0.033 秒)

    Hair-growth agent
    2.
    发明授权
    Hair-growth agent 失效
    头发生长剂

    公开(公告)号：US5741816A

    公开(公告)日：1998-04-21

    申请号：US466968

    申请日：1995-06-06

    申请人： Kenji Tsujihara ,  Kunio Saito ,  Satoshi Furuuchi

    发明人： Kenji Tsujihara ,  Kunio Saito ,  Satoshi Furuuchi

    IPC分类号： A61K8/44 ,  A61Q7/00 ,  C07C229/22 ,  A01N37/02 ,  A01N37/06

    CPC分类号： A61Q7/00 ,  A61K8/44 ,  C07C229/22 ,  Y10S514/88

    摘要： Disclosed is a hair-growing (restoration) agent which comprises a carnitine compound represented by the formula (I): ##STR1## wherein R.sup.1 to R.sup.3 each represent an alkyl group having 1 to 6 carbon atoms; R.sup.4 represents an aliphatic acyl group having 3 to 31 carbon atoms which may be substituted; R.sup.5 represents an alkyl group having 3 to 31 carbon atoms which may be substituted, or an alkenyl group having 3 to 31 carbon atoms which may be substituted; and X.sup.- represents an anion of a pharmaceutically acceptable acid, as an active ingredient.

    摘要翻译： 公开了包含式（I）表示的肉碱化合物的生发（还原剂）：其中R 1至R 3各自表示具有1至6个碳原子的烷基; R4表示可以被取代的碳原子数3〜31的脂肪族酰基， R5表示可以被取代的碳原子数3〜31的烷基或可以被取代的碳原子数3〜31的烯基; X表示药学上可接受的酸的阴离子作为活性成分。

    Aromatic amino acid derivatives and medicinal compositions
    3.
    发明授权
    Aromatic amino acid derivatives and medicinal compositions 有权
    芳香族氨基酸衍生物和药物组合物

    公开(公告)号：US07345068B2

    公开(公告)日：2008-03-18

    申请号：US10503125

    申请日：2003-02-03

    申请人： Hitoshi Endou ,  Yoshikatsu Kanai ,  Kenji Tsujihara ,  Kunio Saito

    发明人： Hitoshi Endou ,  Yoshikatsu Kanai ,  Kenji Tsujihara ,  Kunio Saito

    IPC分类号： C07D235/14 ,  C07D263/57 ,  A61K31/54 ,  A61K31/4745

    CPC分类号： C07D207/325 ,  C07C229/36 ,  C07C233/47 ,  C07C233/69 ,  C07C255/54 ,  C07C271/10 ,  C07C2602/10 ,  C07D209/08 ,  C07D213/30 ,  C07D213/74 ,  C07D215/14 ,  C07D235/18 ,  C07D239/42 ,  C07D263/32 ,  C07D263/56 ,  C07D265/36 ,  C07D277/24 ,  C07D277/66 ,  C07D307/79 ,  C07D307/82 ,  C07D307/83 ,  C07D307/91 ,  C07D311/30 ,  C07D401/04 ,  C07D413/04 ,  C07D417/04 ,  C07D471/06 ,  Y02P20/55

    摘要： 1. An aromatic amino acid derivative represented by the formula (I) or its pharmacologically acceptable salt: wherein, R1 is a hydrogen atom or an amino-protecting group, R2 is a halogen atom or an alkyl, aralkyl or aryl group, R3 is {circle around (1)} a hydrogen atom, {circle around (2)} an aroylamino group, {circle around (3)} a phenyl group substituted with lower alkyl, phenyl, phenoxy, etc. {circle around (4)} a naphthyl or tetrahydronaphthyl group optionally substituted with hydroxy, lower alkoxy or di(lower)alkylamino, {circle around (5)} an unsaturated mono-cyclic heterocyclic group containing N, O and/or S substituted with lower alkyl, phenyl, naphthyl or tetrahydroquinolyl, {circle around (6)} an unsaturated or partially saturated condensed heterocyclic group containing N, O and/or S, optionally substituted with oxo, carboxy, amino, lower alkyl, etc.; X is a halogen atom, an alkyl group or an alkoxy group; Y is oxygen atom or nitrogen atom; l is 0 or 1; m is 0, 1 or 2; n is an integer of 0-5. This compound can inhibit a transporter (LAT1) of essential amino acid which is one of main nutrition for cancer cells and accordingly cause drain of the essential amino acid on the cancer cells and finally can prohibit the multiplication of cancer cells.

    摘要翻译： 1.由式（I）表示的芳族氨基酸衍生物或其药理学上可接受的盐：其中R 1是氢原子或氨基保护基，R 2 O >是卤素原子或烷基，芳烷基或芳基，R 3是（环绕（1个氢原子，{环周围（2个芳酰氨基，{环周（3个苯基） 取代为低级烷基，苯基，苯氧基等。（四个萘基或四氢萘基，任选被羟基，低级烷氧基或二（低级）烷基氨基取代，（环绕（5个含有N的不饱和单环杂环基） O和/或S被低级烷基，苯基，萘基或四氢喹啉基取代，{环绕（6个不饱和或部分饱和的含有N，O和/或S的稠合杂环基，任选被氧代，羧基，氨基，低级烷基， X是卤素原子，烷基或烷氧基; Y是氧原子或氮原子; l是0或1; m 是0，1或2; n是0-5的整数。 该化合物可以抑制作为癌细胞的主要营养素之一的必需氨基酸的转运体（LAT1），因此导致癌细胞上必需氨基酸的排出，最终能够抑制癌细胞的增殖。

    Data transmission network
    5.
    发明授权
    Data transmission network 失效
    数据传输网络

    公开(公告)号：US4596013A

    公开(公告)日：1986-06-17

    申请号：US460557

    申请日：1983-01-24

    申请人： Korefumi Tashiro ,  Kunio Saito ,  Hiroshi Takenaga ,  Masahiro Yasunami

    发明人： Korefumi Tashiro ,  Kunio Saito ,  Hiroshi Takenaga ,  Masahiro Yasunami

    IPC分类号： B60L15/42 ,  G08C15/06 ,  H04J3/00 ,  H04L12/43 ,  H04Q3/00 ,  H04Q9/00 ,  H04Q9/16 ,  H04J3/02

    CPC分类号： G08C15/06 ,  H04L12/43

    摘要： The invention discloses a data transmission network having a plurality of data transmission stations connected through a loop-like transmission line for mutual data transmission, wherein a plurality of data frames, each having data packets allocated to the respective stations, are circulated through the transmission line simultaneously, and each station is arranged to send out the data frame to the transmission line immediately after renewing the data of the data packet allocated to that station in the received data frame, and to process the data of the received data frame to be used for the associated equipment after sending out the data frame.

    摘要翻译： 本发明公开了一种数据传输网络，其具有通过环状传输线路连接的多个数据传输站，用于相互数据传输，其中分配有各个站的数据分组的多个数据帧通过传输线循环 同时，并且每个站被布置成在更新在接收到的数据帧中分配给该站的数据分组的数据之后立即将数据帧发送到传输线，并且处理接收的数据帧的数据以用于 相关设备发送数据帧后。

    Power converter system
    10.
    发明授权
    Power converter system 失效
    电源转换器系统

    公开(公告)号：US4245293A

    公开(公告)日：1981-01-13

    申请号：US949120

    申请日：1978-10-06

    申请人： Mutsuhiro Terunuma ,  Seiya Shima ,  Kunio Saito

    发明人： Mutsuhiro Terunuma ,  Seiya Shima ,  Kunio Saito

    IPC分类号： H02M7/155 ,  G05F1/585 ,  H02M1/084 ,  H02M7/162 ,  H02P7/292 ,  H02P13/26

    CPC分类号： H02M7/1626

    摘要： In a power converter system wherein each thyristor of a three-phase full-wave bridge circuit having thyristors connected in all of bridge arms is fired for its controlling to thereby control the dc output voltage, when the dc output voltage is low, the firing angle of a group of thyristors on the negative side is fixed to a large value and the firing angle of a group of thyristors on the positive side is rendered variable within a small range so that a period may occur through which two thyristors connected in series in the full-wave bridge circuit are fired simultaneously. When the dc output voltage is high, the firing angles of groups of thyristors on both the positive and negative sides are made equal to each other and varied simultaneously. The system improves power factor and form factor over the entire controlling range of the dc output voltage.

    摘要翻译： 在功率转换器系统中，其中在所有桥臂中连接有晶闸管的三相全波桥电路的每个晶闸管被激发用于其控制，从而控制直流输出电压，当直流输出电压低时，触发角 的一组晶闸管固定在一个较大的值，一组晶闸管的正极侧的触发角可以在一个很小的范围内变化，从而可能会出现两个晶闸管串联连接的周期 全波桥电路同时发射。 当直流输出电压高时，正侧和负极两侧的晶闸管组的触发角度彼此相等并同时变化。 该系统在直流输出电压的整个控制范围内提高功率因数和形状因数。