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22 条记录 (耗时 0.02 秒)

    Method for the determination of .alpha.-amylase
    2.
    发明授权
    Method for the determination of .alpha.-amylase 失效
    测定α-淀粉酶的方法

    公开(公告)号：US4268628A

    公开(公告)日：1981-05-19

    申请号：US22011

    申请日：1979-03-19

    申请人： Sigmar Klose ,  Hans-Georg Batz ,  Michael Stoltz ,  Alexander Hagen ,  Gunter Weimann

    发明人： Sigmar Klose ,  Hans-Georg Batz ,  Michael Stoltz ,  Alexander Hagen ,  Gunter Weimann

    IPC分类号： G01N33/50 ,  C08B31/00 ,  C12Q1/40 ,  G01N33/02

    CPC分类号： C08B31/00 ,  C12Q1/40 ,  C12Q2334/00 ,  Y10S435/805

    摘要： Novel method for the determination of .alpha.-amylase which method comprises contacting a sample suspected of containing .alpha.-amylase with a starch derivative carrying a substituent capable of dyestuff-forming coupling; separating from the resulting starch-containing phase the low molecular weight soluble fission products formed by splitting of said starch derivative by .alpha.-amylase; coupling the said couplable substituent with another dyestuff forming component; and measuring the dyestuff so formed as a measure of the initial .alpha.-amylase content.

    摘要翻译： 用于测定α-淀粉酶的新方法，该方法包括使怀疑含有α-淀粉酶的样品与携带能够进行染料形成偶联的取代基的淀粉衍生物接触; 从所得含淀粉相中分离出由α-淀粉酶分解所述淀粉衍生物形成的低分子量可溶裂解产物; 将所述可连接取代基与另一种形成染料的成分偶联; 并测量如此形成的染料作为初始α-淀粉酶含量的量度。

    Process and apparatus for preparing multi-component reagent solutions
    3.
    发明授权
    Process and apparatus for preparing multi-component reagent solutions 失效
    制备多组分试剂溶液的方法和装置

    公开(公告)号：US4279991A

    公开(公告)日：1981-07-21

    申请号：US100168

    申请日：1979-12-04

    申请人： Alexander Hagen ,  Hermann Edelmann ,  Sigmar Klose

    发明人： Alexander Hagen ,  Hermann Edelmann ,  Sigmar Klose

    IPC分类号： G01N31/00 ,  C12Q1/00 ,  G01N31/22 ,  G01N33/52 ,  G01N35/00 ,  C12M1/00

    CPC分类号： G01N35/00009 ,  C12Q1/00 ,  G01N31/22 ,  G01N33/521 ,  Y10S435/805 ,  Y10T83/169 ,  Y10T83/2066 ,  Y10T83/902

    摘要： The invention provides a process for the production of reagent solutions containing a plurality of components for analytical purposes, wherein the individual components of several differently composed reagents are each introduced into a solid, proportionable carrier material in easily redissolvable form in such an amount that each part by volume or weight of the carrier material carries a definite amount of one reagent component, the carriers of the components are brought together in a magazine-like manner and, for the production of a particular reagent, from all carriers which carry a component of the reagent, there are simultaneously taken off the amounts corresponding to the required amounts of the components, which are then dissolved to form the reagent solution. Apparatus for carrying out the process is also provided.

    摘要翻译： 本发明提供一种用于生产含有用于分析目的的多种组分的试剂溶液的方法，其中几种不同组成的试剂的各组分各自以容易再溶解的形式引入固体，可配比的载体材料中， 载体材料的体积或重量承载一定量的一种试剂组分，将组分的载体以杂志状的方式汇集在一起​​，并且为了生产特定试剂，从携带一种试剂组分的所有载体 试剂，同时取出与所需量的组分相对应的量，然后将其溶解以形成试剂溶液。 还提供了用于执行该过程的装置。

    Process for enzymatic analysis
    4.
    发明授权
    Process for enzymatic analysis 失效
    酶分析方法

    公开(公告)号：US4102742A

    公开(公告)日：1978-07-25

    申请号：US692701

    申请日：1976-06-03

    申请人： Sigmar Klose ,  Alexander Hagen

    发明人： Sigmar Klose ,  Alexander Hagen

    IPC分类号： C12Q1/00 ,  C12Q1/30 ,  C12Q1/32 ,  C12Q1/54 ,  C12Q1/60 ,  G01N31/14

    CPC分类号： C12Q1/32 ,  C12Q1/00 ,  C12Q1/30 ,  C12Q1/54 ,  C12Q1/60 ,  Y10S435/813

    摘要： Process for enzymatic analysis by the enzymatic reaction of a substance to be determined and measurement of the increase or decrease of a reaction component of the main reaction or subsequent reaction, comprising adding to a solution which contains dissolved therein the enzyme necessary for the reaction, a sample solution containing a substance to be determined, measuring a particular reaction component, and then circulating the enzyme solution through a reactor which completely removes the measured reaction component from the solution (or converts it to a non-disturbing product) and again mixing the enzyme solution, if necessary after replenishing the used up components, with a new sample solution.

    摘要翻译： 通过待测定物质的酶促反应进行酶分析的方法，以及测定主反应或随后反应的反应成分的增加或减少的方法，包括向溶解有反应所需的酶的溶液中加入 含有待测物质的样品溶液，测量特定的反应组分，然后使酶溶液循环通过将溶液中完全除去测量的反应组分的反应器（或将其转化为不干扰产物）并再次混合该酶 解决方案，如果需要，补充用完的组件后，用新的样品溶液。

    Process and device for carrying out analytical determinations
    5.
    发明授权
    Process and device for carrying out analytical determinations 失效
    用于进行分析测定的过程和设备

    公开(公告)号：US4690899A

    公开(公告)日：1987-09-01

    申请号：US751368

    申请日：1985-07-02

    申请人： Sigmar Klose ,  Manfred Pasch ,  Helmut Schlumberger ,  Wolfgang Kleemann ,  Friedhelm Vieth

    发明人： Sigmar Klose ,  Manfred Pasch ,  Helmut Schlumberger ,  Wolfgang Kleemann ,  Friedhelm Vieth

    IPC分类号： G01N33/48 ,  G01N21/07 ,  G01N33/543 ,  G01N33/563 ,  G01N33/68 ,  G01N21/11

    CPC分类号： G01N21/07 ,  G01N33/54366 ,  G01N33/563 ,  G01N33/6857 ,  Y10T436/111666

    摘要： In a process for carrying out an analytical determination by mixing and incubating a sample liquid with at least one dry reagent which is soluble therein to form a reaction mixture liquid and measuring a parameter in the reaction mixture liquid, the sample liquid is first transported along a transport path to the soluble dry reagent and the resulting reaction mixture liquid then further transported along the transport path. The further transporting of the reaction mixture liquid along the transport path is under the influence of a force-change cycle in which centrifugal force and a further force alternately predominate to determine the direction of the further transporting along the transport path. At least one further liquid is transported on another path, part of which is separate from and part of which is common with the transport path, by the force-change cycle in such a manner that at least two of the liquids pass through the common part of the transport path chronologically separated.

    摘要翻译： 在通过将样品液体与可溶于其中的至少一种干试剂混合并孵育以形成反应混合物液体并测量反应混合物液体中的参数的方法进行分析测定的过程中，首先将样品液体沿着 向可溶性干试剂的输送路径和所得到的反应混合物液体进一步沿输送路径输送。 反应混合物液体沿着输送路径的进一步输送受力变化循环的影响，其中离心力和进一步的力交替占主导地位，以确定沿输送路径进一步输送的方向。 至少一个另外的液体在另一个路径上被传送，其中一部分液体通过力 - 变化循环分开并且其一部分与输送路径共同，使得至少两个液体通过公共部分 的运输路径按时间顺序分隔。

    Polychromatic photometer
    6.
    发明授权
    Polychromatic photometer 失效
    多色光度计

    公开(公告)号：US4329062A

    公开(公告)日：1982-05-11

    申请号：US164520

    申请日：1980-07-02

    申请人： Hans-Peter Haar ,  Hermann Edelmann ,  Sigmar Klose

    发明人： Hans-Peter Haar ,  Hermann Edelmann ,  Sigmar Klose

    IPC分类号： G01N21/27 ,  G01N21/13 ,  G01N21/25

    CPC分类号： G01N21/13 ,  G01N21/253

    摘要： In a polychromatic photometer a sample wheel containing angularly spaced sample compartments and a filter wheel containing angularly spaced filters are rotated by a common drive arrangement so that the sample compartments and filters are in turn rotated through and aligned with the optical path of a photometric measuring device. The number of sample compartments is different from the number of filters. The number of sample compartments and the number of filters are not evenly divisible by a common integer. The ratio of the angular velocity of the sample wheel to the angular velocity of the filter wheel is substantially equal to the ratio of the number of filters to the number of sample compartments.

    摘要翻译： 在多色光度计中，包含角度间隔开的样品室和包含角度间隔开的滤光器的滤光轮的样品轮通过公共驱动装置旋转，使得样品室和滤光器又旋转通过并与光度测量装置的光路对准 。 样品室的数量与过滤器的数量不同。 样本室的数量和过滤器的数量不能被公共整数均分。 样品轮的角速度与滤光轮的角速度的比率基本上等于滤光片数与样品室数之比。

    Method and device for metering liquids
    7.
    发明授权
    Method and device for metering liquids 失效
    液体计量方法和装置

    公开(公告)号：US5856200A

    公开(公告)日：1999-01-05

    申请号：US634366

    申请日：1996-04-18

    申请人： Friedemann Krause ,  Sigmar Klose

    发明人： Friedemann Krause ,  Sigmar Klose

    IPC分类号： G01F11/00 ,  B01L3/02 ,  G01B11/10 ,  G01F1/66 ,  G01F3/00 ,  G01F13/00 ,  G01F22/00 ,  G01N33/48 ,  G01N35/10 ,  G06T1/00

    CPC分类号： B01L3/0244 ,  G01F1/661 ,  G01F22/00 ,  G01F3/00 ,  G01N2035/1037 ,  Y10T436/2575

    摘要： The present invention relates to a method and a device for metering liquids, wherein the volume of a droplet of a sample liquid is determined by means of optical measuring. The liquid to be metered is brought into contact with a transfer element so that a droplet adheres to the transfer element. The transfer element and the liquid adhering thereto are illuminated from one or several directions and the resulting images are displayed on an optical sensor. The liquid volume is determined on the basis of these images. Metering is accomplished by transferring the liquid volume adhering to the transfer element into an analysis vessel.

    摘要翻译： 本发明涉及一种用于计量液体的方法和装置，其中通过光学测量来确定样品液体的液滴的体积。 要计量的液体与转印元件接触，使得液滴附着到转印元件上。 传输元件和粘附在其上的液体从一个或多个方向照射，并将所得到的图像显示在光学传感器上。 基于这些图像确定液体体积。 通过将粘附到转移元件的液体体积转移到分析容器中来进行计量。

    Method and reagent for the determination of substances forming hydrogen peroxide
    9.
    发明授权
    Method and reagent for the determination of substances forming hydrogen peroxide 失效
    用于测定形成过氧化氢的物质的方法和试剂

    公开(公告)号：US4101381A

    公开(公告)日：1978-07-18

    申请号：US754878

    申请日：1976-12-27

    申请人： Sigmar Klose ,  Ulfert Deneke ,  Erich Haid ,  Gunter Weimann

    发明人： Sigmar Klose ,  Ulfert Deneke ,  Erich Haid ,  Gunter Weimann

    IPC分类号： G01N33/50 ,  C12Q1/26 ,  C12Q1/28 ,  C12Q1/60 ,  G01N33/00 ,  G01N31/14

    CPC分类号： C12Q1/60 ,  C12Q1/28 ,  C12Q2326/00 ,  C12Q2326/32

    摘要： In a conventional method for the quantitative determination of substances, particularly in serum, which, by action of an oxidase thereon, combine with oxygen to form hydrogen peroxide and wherein the hydrogen peroxide formed is converted, in the presence of methanol and catalase, to formaldehyde, the formaldehyde is reacted with hydrazone in the presence of ferric chloride, and the dye thus formed is determined photometrically, the improvement comprising using as the hydrazone, 3-methyl-2-sulfonylbenzothiazolone-hydrazone; use of this hydrazone results in the formation of a very easily soluble dye and is suited for use in automatic analyzers.

    摘要翻译： 在用于定量测定物质的常规方法中，特别是在血清中，通过其上的氧化酶的作用与氧结合形成过氧化氢，并且其中形成的过氧化氢在甲醇和过氧化氢酶存在下转化成甲醛 ，在氯化铁存在下，甲醛与腙反应，由此形成的染料用光度法测定，其改进包括使用3-甲基-2-磺酰基苯并噻唑酮 - 腙; 使用该腙导致形成非常容易溶解的染料，并且适用于自动分析仪。