Aryl (ethanoic) propanoic acid ascorbyl ester, preparation method thereof and medicament containing the same
    3.
    发明授权
    Aryl (ethanoic) propanoic acid ascorbyl ester, preparation method thereof and medicament containing the same 有权
    (乙酸)丙酸抗坏血酸酯,其制备方法和含有它的药物

    公开(公告)号:US08703975B2

    公开(公告)日:2014-04-22

    申请号:US13320101

    申请日:2009-12-24

    Abstract: The present invention designs and synthesizes the ascorbyl ester derivatives of the aryl (ethanoic) propanoic acid non-steroidal anti-inflammatory medicaments, such as ibuprofen, ketoprofen and naproxen, and addition salt of the derivatives with pharmaceutical acid or pharmaceutical alkaline. The non-steroidal anti-inflammatory medicament which takes the ibuprofen as the representative is a common antipyretic analgesic medicament. The invention has remarkable antipyretic and analgesic effects and good safety except for anti-inflammatory effect, thus being not only suitable for adults, but also suitable for the elderly people, infants and children. The aryl (ethanoic) propanoic acid ascorbyl ester can be converted into ascorbyl ester derivatives and the addition salts of the derivatives with pharmaceutical acid or pharmaceutical alkaline, which can improve the water solubility thereof, facilitate intravenously administration, reduce the onset time, improve the bioavailability, reduce the stimulation effect to gastrointestinal tract, and enhance the penetrating capacity to hemato encephalic barrier, and can be used as a novel medicament to be applied for antiphlogistic, antipyresis, analgesia, treatment of arthritis, dysmenorrheal, multiple sclerosis, pneumonia cystic fibrosis and patent ductus arteriosus of premature infants, and prevention and treatment of cerebral apoplexy, hypoxic-ischemic brain damage, senile dementia and certain cancers.

    Abstract translation: 本发明设计和合成芳基(乙酸)丙酸非甾体抗炎药物如布洛芬,酮洛芬和萘普生的抗坏血酸酯衍生物,以及衍生物与药物酸或药物碱的加成盐。 以布洛芬为代表的非甾体抗炎药是常见的解热止痛药。 本发明除抗炎作用外,具有明显的解热镇痛作用,安全性好,不仅适用于成人,而且适用于老年人,婴儿和儿童。 芳基(乙酸)丙酸抗坏血酸酯可以转化为抗坏血酸酯衍生物,并且衍生物的加成盐与药物酸或药物碱性可以改善其水溶性,有助于静脉内施用,减少发病时间,提高生物利用度 降低对胃肠道的刺激作用,增强血液渗透屏障的穿透能力,可用作新型药物,用于消炎止痛,止痛,止痛,治疗关节炎,痛经,多发性硬化,肺炎囊性纤维化,以及 早产儿动脉导管未闭,预防和治疗脑中风,缺氧缺血性脑损伤,老年性痴呆和某些癌症。

    Polyimide compositions having resistance to water sorption, and methods relating thereto
    4.
    发明申请
    Polyimide compositions having resistance to water sorption, and methods relating thereto 失效
    具有耐水吸附性的聚酰亚胺组合物及其相关方法

    公开(公告)号:US20050154181A1

    公开(公告)日:2005-07-14

    申请号:US10782326

    申请日:2004-02-19

    Abstract: Water absorption resistant polyimide pastes (or solutions), are particularly useful to make electronic screen printable pastes and the electronic components made from these pastes. A group of soluble polyimides and their solvents were discovered to be particularly resistant to moisture absorption. These polyimide solutions optionally contain polyimides also containing cross-linkable monomers and/or thermal cross-linking agents. In addition, these polyimide pastes may optionally contain adhesion promoting agents, blocked isocyanates, metals, metal oxides, and other inorganic fillers. The polyimide pastes (or solutions) of the present invention have a polyimide with a glass transition temperature greater than 250° C., have a water absorption factor of less than 2%, and a have a positive solubility measurement.

    Abstract translation: 吸水性聚酰亚胺浆料(或溶液)对于制造电子丝网印刷浆料和由这些浆料制成的电子部件特别有用。 发现一组可溶性聚酰亚胺及其溶剂特别耐吸湿性。 这些聚酰亚胺溶液任选地含有也含有可交联单体和/或热交联剂的聚酰亚胺。 此外,这些聚酰亚胺浆料可任选地含有粘合促进剂,封闭的异氰酸酯,金属,金属氧化物和其它无机填料。 本发明的聚酰亚胺膏(或溶液)具有玻璃化转变温度大于250℃的聚酰亚胺,吸水系数小于2%,并且具有正的溶解度测量。

    MEDIA PLAYBACK METHOD AND SYSTEM, CONTENT DELIVERY NETWORK DEVICE, AND ADVERTISING SERVER
    5.
    发明申请
    MEDIA PLAYBACK METHOD AND SYSTEM, CONTENT DELIVERY NETWORK DEVICE, AND ADVERTISING SERVER 审中-公开
    媒体播放方法和系统,内容传送网络设备和广告服务器

    公开(公告)号:US20120272266A1

    公开(公告)日:2012-10-25

    申请号:US13538417

    申请日:2012-06-29

    CPC classification number: H04L65/4084 G06Q30/02 H04L67/20 H04L67/306

    Abstract: The present invention discloses a media playback method and system, a CDN device, and an advertising server. The method includes: receiving, by a CDN device, a program playback request sent by a user terminal; if the program playback request carries a user identifier of a user in the CDN device, querying, by the CDN device, a corresponding relation between the user identifier and personalized information according to the user identifier to obtain the personalized information of the user; obtaining, by the CDN device, a link of advertisement content that corresponds to the user from an advertising server, wherein the link of the advertisement content is obtained by the advertising server according to the personalized information of the user and a preset advertisement configuration policy; and sending, by the CDN device or the advertising server, advertisement content corresponding to the link of the advertisement content to the user terminal.

    Abstract translation: 本发明公开了一种媒体播放方法和系统,CDN设备和广告服务器。 该方法包括:由CDN设备接收用户终端发送的节目回放请求; 如果节目播放请求在CDN设备中携带用户的用户标识符,则由CDN设备根据用户标识符查询用户标识符和个性化信息之间的对应关系,以获得用户的个性化信息; 通过CDN设备从广告服务器获取与用户对应的广告内容的链接,其中,广告服务器根据用户的个性化信息和预设的广告配置策略获取广告内容的链接; 以及由CDN设备或广告服务器将与广告内容的链接相对应的广告内容发送到用户终端。

    Aryl (Ethanoic) Propanoic Acid Ascorbyl Ester, Preparation Method Thereof And Medicament Containing The Same
    6.
    发明申请
    Aryl (Ethanoic) Propanoic Acid Ascorbyl Ester, Preparation Method Thereof And Medicament Containing The Same 有权
    (乙酸)丙酸抗坏血酸酯,其制备方法和含有其的药物

    公开(公告)号:US20120115897A1

    公开(公告)日:2012-05-10

    申请号:US13320101

    申请日:2009-12-24

    Abstract: The present invention designs and synthesizes the ascorbyl ester derivatives of the aryl (ethanoic) propanoic acid non-steroidal anti-inflammatory medicaments, such as ibuprofen, ketoprofen and naproxen, and addition salt of the derivatives with pharmaceutical acid or pharmaceutical alkaline. The non-steroidal anti-inflammatory medicament which takes the ibuprofen as the representative is a common antipyretic analgesic medicament. The invention has remarkable antipyretic and analgesic effects and good safety except for anti-inflammatory effect, thus being not only suitable for adults, but also suitable for the elderly people, infants and children. The aryl (ethanoic) propanoic acid ascorbyl ester can be converted into ascorbyl ester derivatives and the addition salts of the derivatives with pharmaceutical acid or pharmaceutical alkaline, which can improve the water solubility thereof, facilitate intravenously administration, reduce the onset time, improve the bioavailability, reduce the stimulation effect to gastrointestinal tract, and enhance the penetrating capacity to hemato encephalic barrier, and can be used as a novel medicament to be applied for antiphlogistic, antipyresis, analgesia, treatment of arthritis, dysmenorrheal, multiple sclerosis, pneumonia cystic fibrosis and patent ductus arteriosus of premature infants, and prevention and treatment of cerebral apoplexy, hypoxic-ischemic brain damage, senile dementia and certain cancers.

    Abstract translation: 本发明设计和合成芳基(乙酸)丙酸非甾体抗炎药物如布洛芬,酮洛芬和萘普生的抗坏血酸酯衍生物,以及衍生物与药物酸或药物碱的加成盐。 以布洛芬为代表的非甾体抗炎药是常见的解热止痛药。 本发明除抗炎作用外,具有明显的解热镇痛作用,安全性好,不仅适用于成人,而且适用于老年人,婴儿和儿童。 芳基(乙酸)丙酸抗坏血酸酯可以转化为抗坏血酸酯衍生物,并且衍生物的加成盐与药物酸或药物碱性可以改善其水溶性,有助于静脉内施用,减少发病时间,提高生物利用度 降低对胃肠道的刺激作用,增强血液渗透屏障的穿透能力,可用作新型药物,用于消炎止痛,止痛,止痛,治疗关节炎,痛经,多发性硬化,肺炎囊性纤维化,以及 早产儿动脉导管未闭,预防和治疗脑中风,缺氧缺血性脑损伤,老年性痴呆和某些癌症。

    Method for extracting edge in photogrammetry with subpixel accuracy
    7.
    发明授权
    Method for extracting edge in photogrammetry with subpixel accuracy 失效
    用子像素精度提取摄影测量中边缘的方法

    公开(公告)号:US07893947B2

    公开(公告)日:2011-02-22

    申请号:US11880903

    申请日:2007-07-26

    Applicant: Xin Fang

    Inventor: Xin Fang

    Abstract: A method for extracting edge with subpixel accuracy in photogrammetry, comprising steps of: a. capturing into a computer a picture, of which the edge is to be extracted; b. defining as a cell four neighboring pixels that form a square; c. recognizing the type of each cell composed of the four pixels; d. finding out side or sides of the cell that intersect with, the edge and figuring out the subpixel accuracy coordinates of the intersection points by linear interpolation; and e. connecting the intersection points to extract the edge. By this method edge curve is extracted rapidly and accurately. The edge determined in this way can be subpixel accurate.

    Abstract translation: 一种用于在摄影测量中提取具有子像素精度的边缘的方法,包括以下步骤:a。 将计算机中的边缘捕获到图像中; b。 定义为形成正方形的四个相邻像素的单元格; C。 识别由四个像素组成的每个单元的类型; d。 找出与边缘相交的单元格的边或边,并通过线性插值计算交点的子像素精度坐标; 和e。 连接交叉点提取边缘。 通过这种方法,边缘曲线被快速准确地提取。 以这种方式确定的边缘可以是子像素准确。

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