利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

36 条记录 (耗时 0.028 秒)

    Thermoplastic polymer composition, molded product, and multilayer structure
    5.
    发明授权
    Thermoplastic polymer composition, molded product, and multilayer structure 有权
    热塑性聚合物组合物，模制产品和多层结构

    公开(公告)号：US07354654B2

    公开(公告)日：2008-04-08

    申请号：US10728991

    申请日：2003-12-08

    申请人： Haruhisa Masuda ,  Hiromichi Nakata ,  Eiji Nakamura ,  Toshiyuki Zento ,  Isamu Okamoto ,  Motohiro Fukuda

    发明人： Haruhisa Masuda ,  Hiromichi Nakata ,  Eiji Nakamura ,  Toshiyuki Zento ,  Isamu Okamoto ,  Motohiro Fukuda

    IPC分类号： C08L53/02

    CPC分类号： C08L53/025 ,  C08L51/006 ,  Y10T428/31909 ,  Y10T428/31913 ,  Y10T428/31917 ,  C08L53/00 ,  C08L2666/02 ,  C08L2666/06

    摘要： A thermoplastic polymer composition having good flexibility and excellent barrier properties with respect to gases and organic liquids, which can be adhesively bonded to a polyolefin resin, this composition comprising an ethylene-vinyl alcohol copolymer (A), a polymer mixture (B) composed of a block copolymer (I) mainly comprising a vinyl aromatic polymer block and a conjugated diene polymer block which may be hydrogenated, and a rubber softener (II), and a polyolefin resin (C), wherein at least part of the block copolymer (I) is modified at a modification ratio of 0.05 wt. % or higher so as to have a functional group capable of reacting with the ethylene-vinyl alcohol copolymer (A), wherein the ISO type A hardness of the thermoplastic polymer composition is not less than 30 and not higher than 90, and the oxygen permeation coefficient is 20,000 mL·20 μm/m2·day·atm or less.

    摘要翻译： 一种热塑性聚合物组合物，其具有良好的柔软性和优异的气体和有机液体的阻隔性，其可以粘合到聚烯烃树脂上，该组合物包含乙烯 - 乙烯醇共聚物（A），聚合物混合物（B） 主要包括乙烯基芳族聚合物嵌段和可被氢化的共轭二烯聚合物嵌段的嵌段共聚物（I）和橡胶软化剂（II）和聚烯烃树脂（C），其中至少部分嵌段共聚物（I ）以0.05重量％的改性比改性。 ％以上，具有能够与乙烯 - 乙烯醇共聚物（A）反应的官能团，其中，热塑性聚合物组合物的ISO A型硬度为30以上且90以下，氧渗透性 系数为20,000mL.20mum / m 2·day.atm或更小。

    CULTURE METHOD, GROUP OF MATURE ADIPOCYTES, DRUG SCREENING METHOD
    6.
    发明申请
    CULTURE METHOD, GROUP OF MATURE ADIPOCYTES, DRUG SCREENING METHOD 审中-公开
    文化方法，成熟组，药物筛选方法

    公开(公告)号：US20140065659A1

    公开(公告)日：2014-03-06

    申请号：US14005508

    申请日：2012-03-16

    申请人： Yoko Itchoda ,  Masaya Hosoda ,  Motohiro Fukuda ,  Masafumi Nagayama

    发明人： Yoko Itchoda ,  Masaya Hosoda ,  Motohiro Fukuda ,  Masafumi Nagayama

    IPC分类号： C12N5/077 ,  G01N33/50

    CPC分类号： C12N5/0653 ,  C12M23/12 ,  C12M25/06 ,  C12N2513/00 ,  G01N33/5044

    摘要： In a culture method for adipocytes, seeded adipocytes are cultured while being allowed to adhere to a culture bottom surface (14) and walls (12) disposed perpendicularly to the culture bottom surface (14), without suspending the adipocytes in a culture solution, thereby obtaining mature adipocytes in which spherical lipid droplets having increased in size are generated within cells. This method uses a culture chamber (10) in which the walls (12) are formed perpendicular to the culture bottom surface (14). Spherical mature adipocytes containing spherical lipid droplets having increased in size within cells are cultured in a state where a cell or an aggregate of cells is allowed to adhere to two or more locations on the walls (12) and the culture bottom surface (14), thereby obtaining adipocytes having a shape similar to that of adipocytes in vivo.

    摘要翻译： 在脂肪细胞的培养方法中，将接种的脂肪细胞培养同时粘附到培养基底表面（14）和垂直于培养物底表面（14）设置的壁（12），而不将脂肪细胞悬浮在培养溶液中，从而 获得其中在细胞内产生尺寸增加的球形脂滴的成熟脂肪细胞。 该方法使用其中壁（12）垂直于培养物底表面（14）形成的培养室（10）。 在允许细胞或细胞聚集体粘附在壁（12）和培养底表面（14）上的两个或更多位置的状态下培养含有细胞内尺寸增加的球形脂滴的球形成熟脂肪细胞， 从而获得具有与体内脂肪细胞相似形状的脂肪细胞。

    CELL CULTURE CONTAINER AND CELL CULTURE METHOD
    7.
    发明申请
    CELL CULTURE CONTAINER AND CELL CULTURE METHOD 有权
    细胞培养容器和细胞培养方法

    公开(公告)号：US20110318829A1

    公开(公告)日：2011-12-29

    申请号：US13229087

    申请日：2011-09-09

    申请人： Go TAZAKI ,  Tomoko Kosaka ,  Motohiro Fukuda

    发明人： Go TAZAKI ,  Tomoko Kosaka ,  Motohiro Fukuda

    IPC分类号： C12N5/071 ,  C12N5/077 ,  C12N5/079

    CPC分类号： C12M23/12 ,  B33Y80/00 ,  C12M23/16

    摘要： To provide a cell culture chamber and a cell culture method that are capable of effectively constructing an intercellular network in a culture space. A cell culture chamber (10) according to the present invention is a cell culture chamber (10) including a plurality of microchambers (11) formed on a surface thereof, characterized in that convex portions (side walls 12) that partition the microchambers (11) adjacent to each other are formed to prevent cells from being adhered to upper surfaces of the convex portions. Consequently, cells can be cultured exclusively within the microchambers (11), and an intercellular network can be constructed effectively.

    摘要翻译： 提供能够有效地构建培养空间中的细胞间网络的细胞培养室和细胞培养方法。 根据本发明的细胞培养室（10）是包括形成在其表面上的多个微室（11）的细胞培养室（10），其特征在于，将微型室（11）分隔开的凸部（侧壁12） ）形成为防止细胞粘附到凸部的上表面。 因此，可以在微室（11）内专门培养细胞，并且可以有效地构建细胞间网络。

    CELL STORAGE METHOD AND CELL TRANSPORT METHOD
    8.
    发明申请
    CELL STORAGE METHOD AND CELL TRANSPORT METHOD 审中-公开
    细胞储存方法和细胞运输方法

    公开(公告)号：US20110207215A1

    公开(公告)日：2011-08-25

    申请号：US13125871

    申请日：2009-10-23

    申请人： Yoko Itchoda ,  Go Tazaki ,  Motohiro Fukuda ,  Hitoshi Tsuruta ,  Hideki Taniguchi

    发明人： Yoko Itchoda ,  Go Tazaki ,  Motohiro Fukuda ,  Hitoshi Tsuruta ,  Hideki Taniguchi

    IPC分类号： C12N5/071 ,  C12N5/0735 ,  C12N5/0793 ,  C12N5/077

    CPC分类号： A01N1/0263 ,  C12M23/12 ,  C12M23/24 ,  C12M23/38 ,  C12M23/54 ,  C12M45/22

    摘要： To provide a cell storage method to store living cells while maintaining the functions of the living cells. An aspect of the cell storage method is a method to store living cells (40) by using a cell culture chamber (20) including a plurality of the microchambers (11), the method including: culturing the living cells by being adhered to the surfaces of a plurality of micro spaces; and after the culturing, pouring the culture medium (50) into the cell culture chamber (20) so as to cover the plurality of microchambers (11), and storing the living cells. The living cells are adhered to a cell culture chamber of an appropriate size and cultured to form a three-dimensional structure. This enables maintaining the three-dimensional structure of the living cells and storage of the living cells while maintaining the functions thereof.

    摘要翻译： 提供细胞储存方法来储存活细胞同时保持活细胞的功能。 细胞储存方法的一个方面是通过使用包括多个微室（11）的细胞培养室（20）来储存活细胞（40）的方法，所述方法包括：通过粘附到所述表面上培养活细胞 的多个微空间; 培养后，将培养基（50）注入到细胞培养室（20）中以覆盖多个微室（11），并储存活细胞。 将活细胞粘附到适当尺寸的细胞培养室并进行培养以形成三维结构。 这能够维持活细胞的三维结构并维持活体的功能。

    Microchannel array
    9.
    发明授权
    Microchannel array 有权
    微通道阵列

    公开(公告)号：US07432110B2

    公开(公告)日：2008-10-07

    申请号：US11659952

    申请日：2005-08-04

    申请人： Yuji Kikuchi ,  Mitsutoshi Nakajima ,  Taiji Nishi ,  Motohiro Fukuda

    发明人： Yuji Kikuchi ,  Mitsutoshi Nakajima ,  Taiji Nishi ,  Motohiro Fukuda

    IPC分类号： G01N1/18

    CPC分类号： B01L3/502761 ,  B01F3/0807 ,  B01F5/0453 ,  B01F5/0456 ,  B01F13/0059 ,  B01L3/502707 ,  B01L2200/0668 ,  B01L2300/0816 ,  C12M23/16 ,  Y10T436/25375

    摘要： A microchannel array according to the present invention includes a first substrate 1, and a second substrate 11 bonded to the first substrate 1. Two sets, that is, a set of a first through-hole 9, a first recess 7, and a first groove 8 and a set of a second through-hole 4, a second recess 2, and a second groove 3 are formed on the first substrate 1. The different sets are separated by a partition 5. A cell differentation/proliferation speed after micro-injection can be increased by using such microchannel array.

    摘要翻译： 根据本发明的微通道阵列包括第一基板1和结合到第一基板1的第二基板11。 两组，即一组第一通孔9，第一凹槽7和第一凹槽8以及一组第二通孔4，第二凹槽2和第二凹槽3形成在 第一基板1。 不同的集合由分区5分隔。 通过使用这种微通道阵列可以增加微注射后的细胞分化/增殖速度。