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    Genetic analysis and authentication
    2.
    发明授权
    Genetic analysis and authentication 有权
    遗传分析和认证

    公开(公告)号：US07425416B2

    公开(公告)日：2008-09-16

    申请号：US11438189

    申请日：2006-05-22

    Applicant: Ghazala Hashmi ,  Michael Seul ,  Joachim Messing

    Inventor： Ghazala Hashmi ,  Michael Seul ,  Joachim Messing

    IPC: C12Q1/68 ,  C07H21/02 ,  C07H21/04

    CPC classification number: C12Q1/6827 ,  B82Y5/00 ,  B82Y10/00 ,  B82Y20/00 ,  C12Q1/6837 ,  C12Q2565/102 ,  C12Q2563/149 ,  C12Q2537/143

    Abstract: This invention provides compositions and methods for genetic testing of an organism and for correlating the results of the genetic testing with a unique marker that unambiguously identifies the organism. The markers may be internal markers, such as for example single nucleotide polymorphisms (SNPs), short tandem repeats (STRs), or other sites within a genomic locus. Alternatively, the markers may be external, such that they are separately added to the genetic sample before testing.

    Abstract translation: 本发明提供了用于生物体的遗传测试的组合物和方法，并且用于将遗传测试的结果与明确识别生物体的唯一标记相关联。 标记可以是内部标记，例如单核苷酸多态性（SNP），短串联重复序列（STR）或基因组基因座内的其他位点。 或者，标记可以是外部的，使得它们在测试之前分开地添加到遗传样品中。

    Gel-shell beads with adsorbed or bound biomolecules
    3.
    发明授权
    Gel-shell beads with adsorbed or bound biomolecules 失效
    具有吸附或结合的生物分子的凝胶 - 壳珠

    公开(公告)号：US07582488B2

    公开(公告)日：2009-09-01

    申请号：US10973700

    申请日：2004-10-26

    Applicant: Sukanta Banerjee ,  Enqing Tan

    Inventor： Sukanta Banerjee ,  Enqing Tan

    IPC: G01N33/544 ,  G01N33/545 ,  G01N33/546 ,  C08F220/18

    CPC classification number: G01N33/5436

    Abstract: Disclosed are gel-coated beads (including Hydrogel™-coated beads), which are capable of adsorbing, or absorbing, proteins and other biomolecules onto or into the gel coating. The gel-coated beads with absorbed or adsorbed biomolecules are suitable for use in an assays, purification or other purposes. The beads have a core made from any of a number of materials, including latex, coated with the gel shell. The biomolecules can be retained within the gel, following adsorption, by covalent attachment, or, by selection of conditions of ambient pH and/or ionic strength such that they are retained without further reaction. Therefore, adsorbed proteins would retain the ability to bind to their respective ligands.

    Abstract translation: 公开了能够将蛋白质和其他生物分子吸附或吸收到凝胶涂层上或凝胶涂层上的凝胶涂覆的珠粒（包括水凝胶涂覆的珠粒）。 具有吸附或吸附的生物分子的凝胶涂覆的珠粒适合用于测定，纯化或其它目的。 珠粒具有由许多材料制成的芯，包括涂有凝胶壳的胶乳。 生物分子可以保留在凝胶内，吸附后，通过共价连接，或通过选择环境pH和/或离子强度的条件使得它们在没有进一步反应的情况下被保留。 因此，吸附的蛋白质将保留结合其各自配体的能力。

    Directed assembly of functional heterostructures
    5.
    发明授权
    Directed assembly of functional heterostructures 有权
    定向组装功能异质结构

    公开(公告)号：US07262063B2

    公开(公告)日：2007-08-28

    申请号：US10034727

    申请日：2001-12-26

    Applicant: Sukanta Banerjee ,  Kairali Podual ,  Michael Seul

    Inventor： Sukanta Banerjee ,  Kairali Podual ,  Michael Seul

    IPC: G01N33/551

    CPC classification number: C08J3/075 ,  C08J3/28 ,  C08J2333/26 ,  C08J2425/06 ,  C12Q1/6837 ,  G01N33/5005 ,  G01N33/545 ,  G03F7/0047 ,  G03F7/164 ,  Y10T428/249952 ,  Y10T428/25

    Abstract: The present invention relates to a systematic process for the creation of functionally organized, spatially patterned assemblies polymer-microparticle composites including the AC electric field-mediated assembly of patterned, self supporting organic (polymeric) films and organic (polymeric)—microparticle composite films of tailored composition and morphology; the present invention further relates to the incorporation of said assemblies into other structures. The present invention. also relates to the application of such functional assemblies in materials science and biology. Additional areas of application include sensors, catalysts, membranes, micro-reactors, smart materials. Miniaturized format for generation of multifunctional thin films. Provides a simple set-up to synthesize thin films of tailored composition and morphology:

    Abstract translation: 本发明涉及一种用于产生功能组织的空间图案化聚合物 - 聚合物 - 微粒复合材料的系统方法，其包括图案化的自支撑有机（聚合物）膜和有机（聚合） - 微粒复合膜的交流电场介导组装 定制组合和形态; 本发明还涉及将所述组件结合到其它结构中。 本发明。 还涉及这种功能组件在材料科学和生物学中的应用。 其他应用领域包括传感器，催化剂，膜，微反应器，智能材料。 用于生成多功能薄膜的小型化格式。 提供简单的设置来合成定制组合和形态的薄膜：

    Directed assembly of functional heterostructures
    6.
    发明授权
    Directed assembly of functional heterostructures 失效
    定向组装功能异质结构

    公开(公告)号：US07625765B2

    公开(公告)日：2009-12-01

    申请号：US11253452

    申请日：2005-10-19

    Applicant: Sukanta Banerjee ,  Kairali Podual ,  Michael Seul

    Inventor： Sukanta Banerjee ,  Kairali Podual ,  Michael Seul

    IPC: G01N33/551

    CPC classification number: C08J3/075 ,  C08J3/28 ,  C08J2333/26 ,  C08J2425/06 ,  C12Q1/6837 ,  G01N33/5005 ,  G01N33/545 ,  G03F7/0047 ,  G03F7/164 ,  Y10T428/249952 ,  Y10T428/25

    Abstract: The present invention relates to a systematic process for the creation of functionally organized, spatially patterned assemblies polymer-microparticle composites including the AC electric field-mediated assembly of patterned, self supporting organic (polymeric) films and organic (polymeric)-microparticle composite films of tailored composition and morphology; the present invention further relates to the incorporation of said assemblies into other structures. The present invention also relates to the application of such functional assemblies in materials science and biology. Additional areas of application include sensors, catalysts, membranes, micro-reactors, smart materials. Miniaturized format for generation of multifunctional thin films. Provides a simple set-up to synthesize thin films of tailored composition and morphology.

    Abstract translation: 本发明涉及一种用于产生功能组织的空间图案化聚合物 - 聚合物 - 微粒复合材料的系统方法，其包括图案化的自支撑有机（聚合物）膜和有机（聚合） - 微粒复合膜的交流电场介导组装 定制组合和形态; 本发明还涉及将所述组件结合到其它结构中。 本发明还涉及这种功能组件在材料科学和生物学中的应用。 其他应用领域包括传感器，催化剂，膜，微反应器，智能材料。 用于生成多功能薄膜的小型化格式。 提供简单的设置来合成定制组合和形态的薄膜。

    Transfusion registry network providing real-time interaction between users and providers of genetically characterized blood products
    7.
    发明授权
    Transfusion registry network providing real-time interaction between users and providers of genetically characterized blood products 有权
    输血注册网络提供用户和遗传特征的血液制品提供者之间的实时交互

    公开(公告)号：US07363170B2

    公开(公告)日：2008-04-22

    申请号：US11092420

    申请日：2005-03-29

    Applicant: Michael Seul ,  Robert James Danegy

    Inventor： Michael Seul ,  Robert James Danegy

    IPC: G06F17/00 ,  C12Q1/68

    CPC classification number: G06F19/322 ,  G06F19/00 ,  G06F19/18 ,  G06F19/24 ,  G06F19/28 ,  G06F19/3481 ,  G06Q10/10 ,  G06Q50/22 ,  G06Q50/24 ,  G16H10/60 ,  G16H40/20 ,  Y02A90/22 ,  Y02A90/26

    Abstract: Disclosed is a registry system, including member institutions, in which transfusion donors and recipients are registered following genotyping, which would typically take place in a member institution, or a member institution would have access to the genotyping information, if performed outside. The registry database can be accessed and searched by members seeking samples of particular type(s). Systems are disclosed for maintaining economic viability of genotyping in connection with transfusions, by maximizing the number of units placed with the minimal number of candidate donors typed. Genotyping of potential donors, and product supply, is matched to forecasted demand. Genotyping can also be limited to the more clinically relevant markers. The registry system can also be integrated with one format of assay which generates an image for analysis, whereby the imaged results can be analyzed and redacted by experts in a central location, and then transmitted back to the patient or their representative.

    Abstract translation: 披露了一个注册系统，包括成员机构，其中输血捐赠者和接受者在基因分型之后注册，通常在成员机构中进行注册，或者成员机构如果在外部执行，则可以访问基因分型信息。 可以通过搜索特定类型的样本的成员访问和搜索注册表数据库。 公开了系统，用于通过最大限度地利用输入的候选捐赠者的数量最大化来维持与输血相关的基因分型的经济可行性。 潜在捐赠者的基因分型和产品供应与预测需求相匹配。 基因分型也可以限于更临床相关的标记物。 注册系统也可以与生成用于分析的图像的一种形式的测定结合，由此可以在中心位置的专家分析和编辑成像结果，然后传送回患者或其代表。

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